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A Person Can Carry And Transmit COVID-19 Without Showing Symptoms, Scientists Confirm – ScienceAlert

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Chinese researchers have confirmed a case of asymptomatic transmission of the new coronavirus: A 20-year-old woman from Wuhan passed it to five of her family members but never got physically sick herself.

The case study is the first concrete evidence that a person showing no symptoms can pass the coronavirus to others – a fact that could make curbing the outbreak even more challenging.

The researchers behind the finding said the 20-year-old woman was isolated and closely observed at the Fifth People’s Hospital of Anyang. She never become physically ill, even after her family members developed fevers. Two of them got severe pneumonia.

For now, the woman’s asymptomatic transmission appears to be an anomaly, but health experts have documented other instances in which people tested positive for the virus without showing symptoms.

A report from the Chinese Centre for Disease Control and Prevention analysed records of all of China’s reported cases of the virus from December 8 to February 11 and found that 1.2 percent of patients confirmed to be infected showed no symptoms.

A far higher portion of asymptomatic cases was found on the Diamond Princess cruise ship, where 322 of 621 people tested positive but showed no symptoms.

“It’s very clear that the people who are getting caught in that umbrella of reporting are the people that present themselves to a hospital,” Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said at a briefing on February 6.

“There’s another whole cohort that is either asymptomatic or minimally symptomatic.”

The Chinese woman tested positive for the virus, but never got sick

The 20-year-old woman in the new case study lives in Wuhan – the city where the outbreak started – but travelled to Anyang on January 10. Three days later, she went with five family members to visit a sick patient (who did not have the coronavirus) at the Anyang District Hospital.

On January 17, one of the woman’s family members came down with a fever and sore throat. The following week, the other four relatives developed a fever and respiratory symptoms. Those relatives were admitted to the Fifth People’s Hospital on January 26.

All of the family members tested positive for the coronavirus. The only person they’d had contact with who had been in Wuhan was their 20-year-old relative.

When doctors initially tested the young woman for the coronavirus, the results came back negative. Her CT scan was normal, too. But a day later, she tested positive for the virus even though she wasn’t showing any symptoms. By February 11, the woman still had no fever, cough, sore throat, or gastrointestinal issues.

(Bai et al., New England Journal of Medicine, 2020)

Doctors concluded that the woman’s incubation period – the time during which she was infectious – was 19 days.

Chinese health officials previously estimated that the incubation period for the virus ranged from one to 14 days, but recent research suggests it could be as long as 24 days.

The US and many other countries have established quarantine rules for travellers from Wuhan based on that 14-day window.

Asymptomatic transmission in Germany?

Most of the coronavirus cases so far have been mild, but the virus has killed more than 2,200 people and infected more than 76,000. Though the majority of cases are on the Chinese mainland, the virus has spread to 29 other countries.

A case of asymptomatic transmission similar to the one described in the new case study was previously identified in Germany. But that research turned out to be flawed.

According to a letter published in the New England Journal of Medicine, a woman from Shanghai transmitted the virus to a 33-year-old German businessman in January. Three days later, he felt better and went back to work, then infected at least two of his colleagues. But the researchers had not spoken with the woman, who had in fact experienced mild symptoms at the time of transmission.

That left scientists unsure as to whether people who never experience any symptoms can transmit the disease – until today.

This article was originally published by Business Insider.

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Canada to donate up to 200,000 vaccine doses to combat mpox outbreaks in Africa

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The Canadian government says it will donate up to 200,000 vaccine doses to fight the mpox outbreak in Congo and other African countries.

It says the donated doses of Imvamune will come from Canada’s existing supply and will not affect the country’s preparedness for mpox cases in this country.

Minister of Health Mark Holland says the donation “will help to protect those in the most affected regions of Africa and will help prevent further spread of the virus.”

Dr. Madhukar Pai, Canada research chair in epidemiology and global health, says although the donation is welcome, it is a very small portion of the estimated 10 million vaccine doses needed to control the outbreak.

Vaccine donations from wealthier countries have only recently started arriving in Africa, almost a month after the World Health Organization declared the mpox outbreak a public health emergency of international concern.

A few days after the declaration in August, Global Affairs Canada announced a contribution of $1 million for mpox surveillance, diagnostic tools, research and community awareness in Africa.

On Thursday, the Africa Centres for Disease Control and Prevention said mpox is still on the rise and that testing rates are “insufficient” across the continent.

Jason Kindrachuk, Canada research chair in emerging viruses at the University of Manitoba, said donating vaccines, in addition to supporting surveillance and diagnostic tests, is “massively important.”

But Kindrachuk, who has worked on the ground in Congo during the epidemic, also said that the international response to the mpox outbreak is “better late than never (but) better never late.”

“It would have been fantastic for us globally to not be in this position by having provided doses a much, much longer time prior than when we are,” he said, noting that the outbreak of clade I mpox in Congo started in early 2023.

Clade II mpox, endemic in regions of West Africa, came to the world’s attention even earlier — in 2022 — as that strain of virus spread to other countries, including Canada.

Two doses are recommended for mpox vaccination, so the donation may only benefit 100,000 people, Pai said.

Pai questioned whether Canada is contributing enough, as the federal government hasn’t said what percentage of its mpox vaccine stockpile it is donating.

“Small donations are simply not going to help end this crisis. We need to show greater solidarity and support,” he said in an email.

“That is the biggest lesson from the COVID-19 pandemic — our collective safety is tied with that of other nations.”

This report by The Canadian Press was first published Sept. 13, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

The Canadian Press. All rights reserved.

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How many Nova Scotians are on the doctor wait-list? Number hit 160,000 in June

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HALIFAX – The Nova Scotia government says it could be months before it reveals how many people are on the wait-list for a family doctor.

The head of the province’s health authority told reporters Wednesday that the government won’t release updated data until the 160,000 people who were on the wait-list in June are contacted to verify whether they still need primary care.

Karen Oldfield said Nova Scotia Health is working on validating the primary care wait-list data before posting new numbers, and that work may take a matter of months. The most recent public wait-list figures are from June 1, when 160,234 people, or about 16 per cent of the population, were on it.

“It’s going to take time to make 160,000 calls,” Oldfield said. “We are not talking weeks, we are talking months.”

The interim CEO and president of Nova Scotia Health said people on the list are being asked where they live, whether they still need a family doctor, and to give an update on their health.

A spokesperson with the province’s Health Department says the government and its health authority are “working hard” to turn the wait-list registry into a useful tool, adding that the data will be shared once it is validated.

Nova Scotia’s NDP are calling on Premier Tim Houston to immediately release statistics on how many people are looking for a family doctor. On Tuesday, the NDP introduced a bill that would require the health minister to make the number public every month.

“It is unacceptable for the list to be more than three months out of date,” NDP Leader Claudia Chender said Tuesday.

Chender said releasing this data regularly is vital so Nova Scotians can track the government’s progress on its main 2021 campaign promise: fixing health care.

The number of people in need of a family doctor has more than doubled between the 2021 summer election campaign and June 2024. Since September 2021 about 300 doctors have been added to the provincial health system, the Health Department said.

“We’ll know if Tim Houston is keeping his 2021 election promise to fix health care when Nova Scotians are attached to primary care,” Chender said.

This report by The Canadian Press was first published Sept. 11, 2024.

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Newfoundland and Labrador monitoring rise in whooping cough cases: medical officer

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ST. JOHN’S, N.L. – Newfoundland and Labrador‘s chief medical officer is monitoring the rise of whooping cough infections across the province as cases of the highly contagious disease continue to grow across Canada.

Dr. Janice Fitzgerald says that so far this year, the province has recorded 230 confirmed cases of the vaccine-preventable respiratory tract infection, also known as pertussis.

Late last month, Quebec reported more than 11,000 cases during the same time period, while Ontario counted 470 cases, well above the five-year average of 98. In Quebec, the majority of patients are between the ages of 10 and 14.

Meanwhile, New Brunswick has declared a whooping cough outbreak across the province. A total of 141 cases were reported by last month, exceeding the five-year average of 34.

The disease can lead to severe complications among vulnerable populations including infants, who are at the highest risk of suffering from complications like pneumonia and seizures. Symptoms may start with a runny nose, mild fever and cough, then progress to severe coughing accompanied by a distinctive “whooping” sound during inhalation.

“The public, especially pregnant people and those in close contact with infants, are encouraged to be aware of symptoms related to pertussis and to ensure vaccinations are up to date,” Newfoundland and Labrador’s Health Department said in a statement.

Whooping cough can be treated with antibiotics, but vaccination is the most effective way to control the spread of the disease. As a result, the province has expanded immunization efforts this school year. While booster doses are already offered in Grade 9, the vaccine is now being offered to Grade 8 students as well.

Public health officials say whooping cough is a cyclical disease that increases every two to five or six years.

Meanwhile, New Brunswick’s acting chief medical officer of health expects the current case count to get worse before tapering off.

A rise in whooping cough cases has also been reported in the United States and elsewhere. The Pan American Health Organization issued an alert in July encouraging countries to ramp up their surveillance and vaccination coverage.

This report by The Canadian Press was first published Sept. 10, 2024.

The Canadian Press. All rights reserved.

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