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AIDS conference: Experts criticize global monkeypox response – CTV News Montreal

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A panel of scientists and activists at the AIDS 2022 conference in Montreal urged worldwide governments over the weekend to ramp up resources to handle the monkeypox outbreaks.

The plea came as international experts gathered on Sunday to discuss the necessity to avoid reproducing mistakes made during the early HIV response.

Marina Klein, research director and professor of medicine at the division of infectious diseases and chronic viral illnesses service at McGill University in Que., said Montreal could set an example as it becomes crucial to improve the monkeypox global response.

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“There was a very rapid response in Montreal to address the rising infections, with the implementation of a very liberal and open, accessible vaccine,” Klein said in an interview on Sunday.

Montreal was the initial epicentre of outbreaks in Canada, with about 360 confirmed cases as of July 29. There are now more than 800 confirmed cases of monkeypox in the country.

But the rate of infections has started to stabilize and hit a plateau in Montreal, Klein said.

“Part of that has come directly from the Public Health Department but also with the involvement of the community, which has been the key to educating about the importance of the vaccine,” she said.

Klein, however, said she worries other provinces, in particular Saskatchewan, won’t have the same ease to connect with vulnerable communities.

“Although there are only two cases as far as identified … we know that in Saskatchewan there’s been many challenges, both with HIV and sexually transmitted infections, especially among vulnerable populations including Indigenous communities,” Klein said.

She stressed the importance of community engagement and having a vaccine response ready to go, but also the need to study the extent of monkeypox transmission.

“We did respond rapidly, but nowhere in the world responded rapidly enough to address this and get rid of this in the short time frame that we needed to,” she said.

“Now we are going to have to switch our gear and think about how do we control this over the long term.”

Her criticisms were echoed by several other speakers at Sunday’s conference.

Keletso Makofane, a public health researcher at Harvard University, called the monkeypox global response “worse than the initial HIV response.”

Over 19,000 cases of monkeypox have been reported over the last few months from 78 countries, mostly among men who have sex with other men.

“We knew enough to have done a lot better to have contained this thing,” Makofane said in an interview, adding that the general fatigue from fighting COVID-19 made the monkeypox response slower than it should have been.

Makofane also decried thousands of vaccine doses sitting in Denmark while the number of cases continues to climb.

Unlike the numerous companies that made COVID-19 vaccines, Denmark’s Bavarian Nordic is the only maker of the vaccine used against monkeypox.

“It’s scandalous and it’s worse than HIV in the sense that we have the tools to respond,” Makofane said.

Dr. Meg Doherty, director of the World Health Organization’s global HIV, hepatitis and STIs programs, told the attendees an equitable approach is crucial to ensure the tools are available not only to wealthier countries, but also in Africa where monkeypox is traditionally found.

“Thirty-five countries have been accessing or asking to have access to the vaccines … is there a risk that countries who are putting in (requests) for access are coming from rich countries? That’s quite a possible risk,” Doherty said on Sunday.

“We want equity. We can’t have a monkeypox response that is only responding to the U.K., Canada and the United States.”

The international AIDS 2022 conference — from July 29 to Tuesday — is expected to attract more than 9,000 delegates from around the world, with another 2,000 registered to participate remotely.

This report by The Canadian Press was first published July 31, 2022.

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RCMP warn about benzodiazepine-laced fentanyl tied to overdose in Alberta – Edmonton Journal

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April 19, 2024

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Grande Prairie RCMP issued a warning Friday after it was revealed fentanyl linked to a deadly overdose was mixed with a chemical that doesn’t respond to naloxone treatment.

The drugs were initially seized on Feb. 28 after a fatal overdose, and this week, Health Canada reported back to Mounties that the fentanyl had been mixed with Bromazolam, which is a benzodiazepine.

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Mounties say this is the first recorded instance of Bromazolam in Alberta. The drug has previously been linked to nine fatal overdoses in New Brunswick in 2022.

The pills seized in Alberta were oval-shaped and stamped with “20” and “SS,” though Mounties say it can come in other forms.

Naloxone treatment, given in many cases of opioid toxicity, is not effective in reversing the effects of Bromazalam, Mounties said, and therefore, any fentanyl mixed with the benzodiazepine “would see a reduced effectiveness of naloxone, requiring the use of additional doses and may still result in a fatality.”

Photo of benzodiazepine-laced fentanyl seized earlier this year by Grande Prairie RCMP after a fatal overdose. edm

From January to November of last year, there were 1,706 opioid-related deaths in Alberta, and 57 linked to benzodiazepine, up from 1,375 and 43, respectively, in 2022.

Mounties say officers responded to about 1,100 opioid-related calls for service, last year with a third of those proving fatal. RCMP officers also used naloxone 67 times while in the field, a jump of nearly a third over the previous year.

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CFIA continues surveillance for HPAI in cattle, while sticking with original name for disease – RealAgriculture

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April 19, 2024

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The Canada Food Inspection Agency will continue to refer to highly pathogenic avian influenza in cattle as HPAI in cattle, and not refer to it as bovine influenza A virus (BIAV), as suggested by the American Association of Bovine Practitioners earlier this month.

Dr. Martin Appelt, senior director for the Canadian Food Inspection Agency, in the interview below, says at this time Canada will stick with “HPAI in cattle” when referencing the disease that’s been confirmed in dairy cattle in multiple states in the U.S.

The CFIA’s naming policy is consistent with the agency’s U.S. counterparts’, as the U.S. Animal and Plant Health Inspection Service has also said it will continue referring to it as HPAI or H5N1.

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Appelt explains how the CFIA is learning from the U.S. experience to-date, and how it is working with veterinarians across Canada to stay vigilant for signs of the disease in dairy and beef cattle.

As of April 19, there has not been a confirmed case of HPAI in cattle in Canada. Appelt says it’s too soon to say if an eventual positive case will significantly restrict animal movement, as is the case with positive poultry cases.

This is a major concern for the cattle industry, as beef cattle especially move north and south across the U.S. border by the thousands. Appelt says that CFIA will address an infection in each species differently in conjunction with how the disease is spread and the threat to neighbouring farms or livestock.

Currently, provincial dairy organizations have advised producers to postpone any non-essential tours of dairy barns, as a precaution, in addition to other biosecurity measures to reduce the risk of cattle contracting HPAI.

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Toronto reports 2 more measles cases. Use our tool to check the spread in Canada – Toronto Star

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Canada has seen a concerning rise in measles cases in the first months of 2024.

By the third week of March, the country had already recorded more than three times the number of cases as all of last year. Canada had just 12 cases of measles in 2023, up from three in 2022.

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