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Alberta study shows DNA may not actually be good predictor of disease, health – Global News

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A new study conducted at the University of Alberta suggests that genes have less to do with developing diseases than previously thought.

The study, which involved scientists examining two decades of data, concluded that DNA contribution to disease development is only about five to 10 per cent.

The data they examined looked at the relationship between common gene mutations (also known as single nucleotide polymorphisms, or SNPs) and different diseases.


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“Simply put, DNA is not your destiny, and SNPs are duds for disease prediction,” said David Wishart, a professor of biological science and computing science at the U of A.

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Throughout the study, the U of A team put the data through simulations and modelling systems, looking for correlations in genes and disease.

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“We looked at around 220 different diseases and about 590 different studies, and tried to put all that information together and determine just how much do your genes, or these SNPs, effect your likelihood or risk of getting a disease,” Wishart said.


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The study did highlight some exceptions: Crohn’s disease, celiac disease and macular degeneration have a genetic contribution of approximately 40 to 50 per cent.

“Despite these rare exceptions, it is becoming increasingly clear that the risk for getting most diseases arise from your metabolism, your environment, your lifestyle, or your exposure to various kinds of nutrients, chemicals, bacteria or viruses,” Wishart said.

“You can’t change your genes. But you can change what you eat, you can change your exercise and lifestyle.”

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Wishart said that he believes that genetic testing companies like 23andMe and AncestryDNA are still reliable for finding out ancestry but that they aren’t reliable for disease risks.

“[Disease prediction] has to be taken very lightly,” Wishart said. “Our data tells us that these [DNA factors] are not important risk factors. The projected risk that they’re arguing or suggesting is often highly inflated.”






1:44
DNA test connected 10 siblings but how reliable are tests?


DNA test connected 10 siblings but how reliable are tests?

© 2019 Global News, a division of Corus Entertainment Inc.

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Quebec reports 698 new COVID-19 cases, seven more deaths – Wiarton Echo

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That’s the highest single-day count since May 21.

Quebec has recorded 698 new cases of COVID-19 — the highest single-day count since May 21 — bringing the province’s total to 71,005 as of Saturday.

Seven new deaths have been reported, all of which occurred between Sept. 19 and 24. The province’s death toll now stands at 5,821.

The number of hospitalizations increased by 18, for a total of 217. Of those, 33 were in intensive care.

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19 new coronavirus cases reported in Saskatchewan, hits single-day testing record – Global News

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Winnipeg police say a woman has died and several other people have been injured in a collision involving a vehicle that was fleeing police.

The crash happened at about 1:30 p.m. Saturday in the area of Salter Street and Boyd Avenue, police said in a statement.

According to police, officers tried to pull over a vehicle for a traffic stop but the driver “took off at a high rate of speed.”

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Seconds later, the vehicle hit another car in the nearby intersection of Andrews Street and Boyd Avenue.

Four people in the vehicle that was struck — including an infant and a child — were sent to hospital.  A woman who was in that vehicle has died from her injuries, police said.

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Two people from the vehicle that had fled police were also transported to hospital.






0:24
No injuries reported after school bus crashes into hydro pole in downtown Winnipeg


No injuries reported after school bus crashes into hydro pole in downtown Winnipeg

The Independent Investigation Unit of Manitoba, which investigates serious incidents involving police, has been called to investigate.

In a press conference Saturday evening, Winnipeg Police Const. Rob Carver said that almost everyone in the collision was in either serious or critical condition.

“Incredibly tragic, we’ve got an infant in the vehicle, a child in the vehicle, a woman who was killed in this crash, tragic all around,” said Carver, who also stressed that the incident was not a result of a police pursuit.

A photo of the crash scene near Salter Street and Boyd Avenue.


A photo of the crash scene near Salter Street and Boyd Avenue.


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“We pulled up, we attempted to have this vehicle spoken to, and the vehicle fled. We did not pursue it.”

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For the two people in the fleeing vehicle, Carver said he does not have an idea on their injuries, but that they will at some point be taken into custody “when their medical condition allows for that.”

“In the space of less than half a minute … what started out as a routine incident ended up with multiple people in the hospital and a woman killed, and these people were not connected at all.”

— With files from Global News’ David Lao

© 2020 Global News, a division of Corus Entertainment Inc.

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Possible COVID-19 exposure at three Saskatoon businesses: SHA – CTV News Saskatoon

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SASKATOON —
The Saskatchewan Health Authority (SHA) is warning of a possible COVID-19 exposure at three Saskatoon businesses in the last week. 

The SHA said a person or persons attended the following locations while likely infectious:

• Sept. 19 – Walmart Supercentre at 225 Betts Ave. in Saskatoon from 4 to 6 p.m.

• Sept. 22 – Planet Fitness at Market Mall on 2325 Preston Ave. S in Saskatoon from 4 to 6 p.m.

• Sept. 23 – KFC at 1808 McOrmond Drive in Saskatoon from 5 to 10 p.m.

The SHA is advising anyone who was at these locations on the specified dates and times to self monitor for 14 days or immediately self isolate and call HealthLine 811 if they develop symptoms of COVID-19. 

People may develop symptoms between two and 14 days after getting exposed to the virus, according to the SHA.

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