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Ancient chewing gum reveals reveals identity of chewer and what she ate – CBC.ca

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Discovering old, used chewing gum is rarely a cause for celebration. It’s a little different, though, when that gum is found in a nearly 6,000-year-old archeological site and preserves the genome of the Neolithic woman who was chewing it.  

The gum was found on an island in southern Denmark. The researchers who analyzed it were able to extract DNA from the chewer that had been trapped in the gum 5,700 years ago. The DNA revealed the sex of the chewer, and also some of her physical attributes.  

“She had this really striking combination of dark skin and dark hair and blue eyes. And of course, we also recovered the microbial DNA which added a whole lot more,” said archeologist Hannes Schroeder, in conversation with Quirks & Quarks host Bob McDonald.  Schroeder is an assistant professor of archeology at the University of Copenhagen,

This is the first time ever scientists have extracted an entire ancient genome from anything other than bone or teeth, giving insight into some of Europe’s early inhabitants and their lifestyle. 

“It is quite amazing — 10 to 15 years ago, nobody thought we would get an ancient genome, full stop. And now we’re able to recover ancient genomes from something like an ancient piece of chewing gum,” said Schroeder about his findings. The team’s work was published in the journal Nature Communications

This is interesting because it tells us something about the evolution of lighter skin tones in this part of the world as a way of adapting to these light poor environments.– Hannes Schroeder

This DNA recovered in the gum is just the latest genetic evidence of dark skinned individuals living in Europe thousands of years ago. 

“This is interesting because it tells us something about the evolution of lighter skin tones in this part of the world as a way of adapting to these light-poor environments,” said Schroeder.

DNA reveals hunter gatherer ancestry

When Schroeder and his colleagues analyzed this Stone Age woman’s DNA, they found it very closely resembled the genomes of hunter gatherers who lived in Europe 6,000 to 10,000 years ago.

“And that fit also with the fact that we recovered plant and animal DNA from the gum as well, which we found to be hazelnuts and duck DNA. And these are obviously wild resources,” added Schroeder

He said this is interesting because at the time this female was eating wild duck and hazelnuts in what is now Denmark, there were already farming communities present just a hundred kilometres away in Germany.

“But it looks like she and her community were still genetically hunter gatherers and also living still a hunter gatherer lifestyle.”

An artist’s illustration of what the ancient gum chewer who lived in Scandinavia would have looked like. (Tom Björklund)

Ancient uses for chewing gum

Scientists had previously discovered this gum-like substance on tools from similar Stone Age archeological sites where the gum was used as a glue to help hold the parts of the tools together.

The gum was derived from birch pitch. Schroeder said it was made by boiling birch bark to extract the pitch. The gooey substance solidifies when cooled. 

“Then in order to make it usable, people used to chew it.”

We identified a number of bacterial species, for instance, that are involved in different forms of tooth decay.– Hannes Schroeder, University of Copenhagen

Microbial treasure trove

Schroeder said one of the more exciting aspects of their discovery is that they were also able to extract DNA from microbes that would have been in the woman’s mouth — her oral microbiome.  

Most of the bacterial species they discovered were harmless and very closely resembled modern oral microbiomes.

“But then there are some that are potentially really pathogenic,” he added. 

This suggests another possible reason why the woman would have been chewing the gum. The gum contains antibacterial compounds and might have been used as a way to fight cavities and toothaches.

“We identified a number of bacterial species, for instance, that are involved in different forms of tooth decay,” he said. 

They also discovered a streptococcus species responsible for developing pneumonia, as well as viral DNA from the Epstein-Barr virus that causes glandular fever.

“Through that, we can’t say whether she had pneumonia or glandular fever, but we know that she was infected with these particular pathogens.”

Schroeder said the fact they were able to even recover the microbial DNA from an ancient piece of chewing gum “opens up entirely new avenues of research.”

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Canada to donate up to 200,000 vaccine doses to combat mpox outbreaks in Africa

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The Canadian government says it will donate up to 200,000 vaccine doses to fight the mpox outbreak in Congo and other African countries.

It says the donated doses of Imvamune will come from Canada’s existing supply and will not affect the country’s preparedness for mpox cases in this country.

Minister of Health Mark Holland says the donation “will help to protect those in the most affected regions of Africa and will help prevent further spread of the virus.”

Dr. Madhukar Pai, Canada research chair in epidemiology and global health, says although the donation is welcome, it is a very small portion of the estimated 10 million vaccine doses needed to control the outbreak.

Vaccine donations from wealthier countries have only recently started arriving in Africa, almost a month after the World Health Organization declared the mpox outbreak a public health emergency of international concern.

A few days after the declaration in August, Global Affairs Canada announced a contribution of $1 million for mpox surveillance, diagnostic tools, research and community awareness in Africa.

On Thursday, the Africa Centres for Disease Control and Prevention said mpox is still on the rise and that testing rates are “insufficient” across the continent.

Jason Kindrachuk, Canada research chair in emerging viruses at the University of Manitoba, said donating vaccines, in addition to supporting surveillance and diagnostic tests, is “massively important.”

But Kindrachuk, who has worked on the ground in Congo during the epidemic, also said that the international response to the mpox outbreak is “better late than never (but) better never late.”

“It would have been fantastic for us globally to not be in this position by having provided doses a much, much longer time prior than when we are,” he said, noting that the outbreak of clade I mpox in Congo started in early 2023.

Clade II mpox, endemic in regions of West Africa, came to the world’s attention even earlier — in 2022 — as that strain of virus spread to other countries, including Canada.

Two doses are recommended for mpox vaccination, so the donation may only benefit 100,000 people, Pai said.

Pai questioned whether Canada is contributing enough, as the federal government hasn’t said what percentage of its mpox vaccine stockpile it is donating.

“Small donations are simply not going to help end this crisis. We need to show greater solidarity and support,” he said in an email.

“That is the biggest lesson from the COVID-19 pandemic — our collective safety is tied with that of other nations.”

This report by The Canadian Press was first published Sept. 13, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

The Canadian Press. All rights reserved.

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How many Nova Scotians are on the doctor wait-list? Number hit 160,000 in June

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HALIFAX – The Nova Scotia government says it could be months before it reveals how many people are on the wait-list for a family doctor.

The head of the province’s health authority told reporters Wednesday that the government won’t release updated data until the 160,000 people who were on the wait-list in June are contacted to verify whether they still need primary care.

Karen Oldfield said Nova Scotia Health is working on validating the primary care wait-list data before posting new numbers, and that work may take a matter of months. The most recent public wait-list figures are from June 1, when 160,234 people, or about 16 per cent of the population, were on it.

“It’s going to take time to make 160,000 calls,” Oldfield said. “We are not talking weeks, we are talking months.”

The interim CEO and president of Nova Scotia Health said people on the list are being asked where they live, whether they still need a family doctor, and to give an update on their health.

A spokesperson with the province’s Health Department says the government and its health authority are “working hard” to turn the wait-list registry into a useful tool, adding that the data will be shared once it is validated.

Nova Scotia’s NDP are calling on Premier Tim Houston to immediately release statistics on how many people are looking for a family doctor. On Tuesday, the NDP introduced a bill that would require the health minister to make the number public every month.

“It is unacceptable for the list to be more than three months out of date,” NDP Leader Claudia Chender said Tuesday.

Chender said releasing this data regularly is vital so Nova Scotians can track the government’s progress on its main 2021 campaign promise: fixing health care.

The number of people in need of a family doctor has more than doubled between the 2021 summer election campaign and June 2024. Since September 2021 about 300 doctors have been added to the provincial health system, the Health Department said.

“We’ll know if Tim Houston is keeping his 2021 election promise to fix health care when Nova Scotians are attached to primary care,” Chender said.

This report by The Canadian Press was first published Sept. 11, 2024.

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Newfoundland and Labrador monitoring rise in whooping cough cases: medical officer

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ST. JOHN’S, N.L. – Newfoundland and Labrador‘s chief medical officer is monitoring the rise of whooping cough infections across the province as cases of the highly contagious disease continue to grow across Canada.

Dr. Janice Fitzgerald says that so far this year, the province has recorded 230 confirmed cases of the vaccine-preventable respiratory tract infection, also known as pertussis.

Late last month, Quebec reported more than 11,000 cases during the same time period, while Ontario counted 470 cases, well above the five-year average of 98. In Quebec, the majority of patients are between the ages of 10 and 14.

Meanwhile, New Brunswick has declared a whooping cough outbreak across the province. A total of 141 cases were reported by last month, exceeding the five-year average of 34.

The disease can lead to severe complications among vulnerable populations including infants, who are at the highest risk of suffering from complications like pneumonia and seizures. Symptoms may start with a runny nose, mild fever and cough, then progress to severe coughing accompanied by a distinctive “whooping” sound during inhalation.

“The public, especially pregnant people and those in close contact with infants, are encouraged to be aware of symptoms related to pertussis and to ensure vaccinations are up to date,” Newfoundland and Labrador’s Health Department said in a statement.

Whooping cough can be treated with antibiotics, but vaccination is the most effective way to control the spread of the disease. As a result, the province has expanded immunization efforts this school year. While booster doses are already offered in Grade 9, the vaccine is now being offered to Grade 8 students as well.

Public health officials say whooping cough is a cyclical disease that increases every two to five or six years.

Meanwhile, New Brunswick’s acting chief medical officer of health expects the current case count to get worse before tapering off.

A rise in whooping cough cases has also been reported in the United States and elsewhere. The Pan American Health Organization issued an alert in July encouraging countries to ramp up their surveillance and vaccination coverage.

This report by The Canadian Press was first published Sept. 10, 2024.

The Canadian Press. All rights reserved.

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