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Asteroid Samples Brought to Earth Contain Key Molecules for Life – Gizmodo

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A canister containing a sample from Ryugu, given to NASA by Japanese space agency JAXA.
Photo: NASA/Robert Markowitz

Japan’s education ministry says that more than 20 types of amino acids were detected in samples of an asteroid that were brought to Earth in December 2020, The Japan Times reports. The detection is the first evidence that amino acids exist on asteroids in space and has implications for understanding how such vital organic molecules arrived on Earth.

The Hayabusa2 spacecraft collected the samples from an asteroid named Ryugu. The Japan Aerospace Exploration Agency (JAXA) probe landed on Ryugu—nearly 200 million miles from Earth—in 2019, and it collected about 5.4 grams of samples from the asteroid’s surface and subsurface.

Ryugu is a carbon-rich fragment of a larger asteroid that formed from the same gas and dust that gave way to our solar system. Because of their age, dust and rocks from Ryugu’s surface offer scientists a look at what material was floating around in the early solar system over 4 billion years ago.

At the Lunar and Planetary Science Conference held in Texas in March, Hisayoshi Yurimoto, a geoscientist at Hokkaido University in Japan and a member of the Hayabusa2 team, described the distant asteroid as “the most primitive material in the solar system we have ever studied,” according to Space.com.

Today’s news reveals the sizable number of amino acids on the distant space rock, which members of the Hayabusa2 team believe could spread through the solar system in the form of interplanetary dust.

Amino acids are the building blocks of proteins, making them essential organic molecules for life. Ancient rocks on Earth have offered evidence that similar molecules to those found on Ryugu arrived here billions of years ago.

“Our final objective is to understand how organic compounds formed in the extraterrestrial environment,” said Hiroshi Naraoka, a geochemist at Kyushu University in Japan, and a member of the Hayabusa2 team, in a 2020 NASA release. “So we want to analyze many organic compounds, including amino acids, sulfur compounds, and nitrogen compounds, to build a story of the types of organic synthesis that happens in asteroids.”

It’s possible that such essential organic molecules first arrived on Earth through impacts from comets and asteroids, and the Ryugu samples have now proven that these molecules exist on asteroids in space. That’s important, because asteroid and cometary impacts on Earth are almost immediately contaminated with terrestrial matter, which can make it difficult for scientists to separate what was always on the rock from what newly tainted it.

As more data from Ryugu samples are analyzed, we’ll get more information about the asteroid’s composition and how it formed. By comparing results from the Ryugu material to the samples collected from Bennu, an asteroid visited by NASA in 2020, we’ll get a better understanding of the various chemical cocktails in the cosmos, and perhaps how life arose from it all.

More: Asteroid Sample Brought to Earth Exposes Ryugu’s Hidden Interior

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Astronaut study reveals effects of space travel on human bones – Euronews

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By Will Dunham

WASHINGTON – A study of bone loss in 17 astronauts who flew aboard the International Space Station is providing a fuller understanding of the effects of space travel on the human body and steps that can mitigate it, crucial knowledge ahead of potential ambitious future missions.

The research amassed new data on bone loss in astronauts caused by the microgravity conditions of space and the degree to which bone mineral density can be regained on Earth. It involved 14 male and three female astronauts, average age 47, whose missions ranged from four to seven months in space, with an average of about 5-1/2 months.

A year after returning to Earth, the astronauts on average exhibited 2.1% reduced bone mineral density at the tibia – one of the bones of the lower leg – and 1.3% reduced bone strength. Nine did not recover bone mineral density after the space flight, experiencing permanent loss.

“We know that astronauts lose bone on long-duration spaceflight. What’s novel about this study is that we followed astronauts for one year after their space travel to understand if and how bone recovers,” said University of Calgary professor Leigh Gabel, an exercise scientist who was the lead author of the research published this week in the journal Scientific Reports https://www.nature.com/articles/s41598-022-13461-1.

“Astronauts experienced significant bone loss during six-month spaceflights – loss that we would expect to see in older adults over two decades on Earth, and they only recovered about half of that loss after one year back on Earth,” Gabel said.

The bone loss occurs because bones that typically would be weight-bearing on Earth do not carry weight in space. Space agencies are going to need to improve countermeasures – exercise regimes and nutrition – to help prevent bone loss, Gabel said.

“During spaceflight, fine bone structures thin, and eventually some of the bone rods disconnect from one another. Once the astronaut comes back to Earth, the remaining bone connections can thicken and strengthen, but the ones that disconnected in space can’t be rebuilt, so the astronaut’s overall bone structure permanently changes,” Gabel said.

The study’s astronauts flew on the space station in the past seven years. The study did not give their nationalities but they were from the U.S. space agency NASA, Canadian Space Agency, European Space Agency and Japan Aerospace Exploration Agency.

Space travel poses various challenges to the human body – key concerns for space agencies as they plan new explorations. For instance, NASA is aiming to send astronauts back to the moon, a mission now planned for 2025 at the earliest. That could be a prelude to future astronaut missions to Mars or a longer-term presence on the lunar surface.

“Microgravity affects a lot of body systems, muscle and bone being among them,” Gabel said.

“The cardiovascular system also experiences many changes. Without gravity pulling blood towards our feet, astronauts experience a fluid shift that causes more blood to pool in the upper body. This can affect the cardiovascular system and vision.

“Radiation is also a large health concern for astronauts as the further they travel from Earth the greater exposure to the sun’s radiation and increased cancer risk,” Gabel said.

The study showed that longer space missions resulted both in more bone loss and a lower likelihood of recovering bone afterward. In-flight exercise – resistance training on the space station – proved important for preventing muscle and bone loss. Astronauts who performed more deadlifts compared to what they usually did on Earth were found to be more likely to recover bone after the mission.

“There is a lot we still do not know regarding how microgravity affects human health, particularly on space missions longer than six months, and on the long-term health consequences,” Gabel said. “We really hope that bone loss eventually plateaus on longer missions, that people will stop losing bone, but we don’t know.”

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Understanding Plants Is Key to Finding a Cure for Cancer – SciTechDaily

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The scientists state that if they can understand unchecked plant growth, they believe they can find a cure for cancer.

If scientists can fully understand plant growth, they might be able to find a cancer cure

In order to increase agricultural yields, it is important to understand how plants process light. Plants use light to determine when to grow and bloom. Plants find light using proteins called photoreceptors. However, understanding plants have impacts in fields other than agriculture.  Ullas Pedmale, an assistant professor at Cold Spring Harbor Laboratory (CSHL), and his colleagues have discovered how the proteins UBP12 and UBP13 regulate the activity of a CRY2 photoreceptor. Their finding could make new growth-control strategies apparent, with potential implications well beyond agriculture.

There are CRY photoreceptors in both plants and people. They are connected to a number of conditions including diabetes, cancer, and several brain disorders.  CRY2 helps in regulating growth in both people and plants. Uncontrolled development in plants reduces their viability, whereas it causes cancer in humans. “If we understand growth,” Pedmale says, “we can cure cancer.”

Plant CRY2 Protein

Manipulating the levels of CRY2 and UBP12 and UBP13 proteins in Arabidopsis thaliana plants affects growth. The first plant from the left shows normal growth. The second plant is missing CRY2 and grew too much. The third plant lacked UBP12 and UBP13 and grew shorter. The fourth plant had high levels of UBP12 and UBP13, and the fifth had high levels of CRY2. Credit: Pedmale lab/CSHL, 2022

Plants need the right amount of CRY2 to know when to grow and flower. Pedmale and former postdoctoral fellow Louise Lindbäck discovered that manipulating UBP12 and UBP13 can change the amount of CRY2 in plants. They found that increasing UBP12 and UBP13 reduces CRY2 levels. This made plants think there wasn’t enough light. In response, they grew longer, abnormal stems to reach more. Pedmale says:

“We have a way to understand growth here—and we could manipulate growth just by manipulating two proteins. We have found a way we can actually increase flower output. You need flowering for food. If there’s no flower, there is no grain, no rice, no wheat, no maize.”

Pedmale and Lindbäck didn’t know exactly how UBP12 and UBP13 regulated CRY2. When the researchers took a closer look, they made a surprising discovery. In humans and other organisms, versions of UBP12 and UBP13 protect CRY photoreceptors from degradation. But in plants, the team saw the opposite. UBP12 and UBP13 were actually helping degrade CRY2 instead. Lindbäck, who is currently a research and developmental engineer at Nordic Biomarker in Sweden, explains:

“From literature, it’s known that if you find an interaction like this, it will protect from degradation. Initially, we saw the opposite, and we thought, ‘okay, maybe I did something wrong,’ but then when I did it a few times, we realized, ‘okay, this is true.’ Instead of protecting CRY2, it causes CRY2 to degrade.”

Pedmale hopes their discovery will help plant researchers and plant breeders improve crop yields. He also hopes his work helps inform cancer research. “My colleagues at CSHL are working hard trying to understand cancer,” he says. “We are coming at it from a different angle with plants.”

The study was funded by the National Institutes of Health. 

Reference: “UBP12 and UBP13 deubiquitinases destabilize the CRY2 blue light receptor to regulate Arabidopsis growth” by Louise N. Lindbäck, Yuzhao Hu, Amanda Ackermann, Oliver Artz and Ullas V. Pedmale, 13 June 2022, Current Biology. 
DOI: 10.1016/j.cub.2022.05.046

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Rocket Lab's Lunar Photon Completes Sixth Orbit Raise for NASA's CAPSTONE Mission to The Moon – Parabolic Arc – Parabolic Arc

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CAPSTONE (Credit: Terran Orbital)

LONG BEACH, Calif. (Rocket Lab PR) — Rocket Lab USA, Inc. (Nasdaq: RKLB) (“Rocket Lab” or “the Company”), a leading launch and space systems company, today confirmed its Photon Lunar spacecraft successfully completed a sixth on-orbit burn of the HyperCurie engine, bringing the CAPSTONE satellite closer to the Moon. Lunar Photon’s apogee – the point at which the spacecraft is farthest from Earth during its orbit – is now 43,297 miles (69,680 km).

This sixth burn was originally scheduled to be two burns, but Rocket Lab’s space systems team determined the HyperCurie engine would be capable of performing a single maneuver to accomplish the same delta-v, so combined the two.

The next and final burn is designed to set CAPSTONE on a ballistic lunar transfer trajectory to the Moon travelling at 24,500 mph (39,400 km/h) to break free of Earth’s orbit. This final maneuver is currently scheduled to take place as early as July 4th. After separating from Lunar Photon, CAPSTONE will use its own propulsion and the Sun’s gravity to navigate the rest of the way to the Moon, a four-month journey that will have CAPSTONE arriving to its lunar orbit on Nov. 13.

ABOUT CAPSTONE:

Designed and built Terran Orbital, and owned and operated by Advanced Space on behalf of NASA, the Cislunar Autonomous Positioning System Technology Operations and Navigation Experiment (CAPSTONE) satellite will be the first spacecraft to test the Near Rectilinear Halo Orbit (NRHO) around the Moon. This is the same orbit intended for NASA’s Gateway, a multipurpose Moon-orbiting station that will provide essential support for long-term astronaut lunar missions as part of the Artemis program. CAPSTONE was successfully launched to space on Rocket Lab’s Electron launch vehicle on June 28.

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