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Bugworks raises $7.5 m from global investment syndicate – BusinessLine

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Bugworks Research Inc, a biopharma start-up that designs novel broad-spectrum antibiotics, has raised $7.5 million from a global investment syndicate to combat the challenge posed by deadly bacterial superbugs.

The funding was led by University of Tokyo Edge Capital (UTEC) Japan and Global Brain Corporation (Global Brain) Japan, along with Acquipharma Holdings, South Africa. After this round, the start-up has raised $19 million till date with 3one4 Capital as an existing investor.

This investment enables Bugworks to complete Phase-I studies for its GYROX series intravenous drug candidate and advance an oral lead towards clinical development. Bugworks’ drug candidate, a dual-target gyrase-topoisomerase inhibitor supported by CARB-X since 2017, is a novel broad-spectrum agent targeting critical bacterial infections implicated in serious hospital, community and bio-threat indications.

“This new financing is an endorsement of our team and differentiated AMR (antimicrobial resistance) assets, as we bring reputed global investors to aid our mission of pandemic preparedness by defeating superbug infections,” said Anand Anandkumar, CEO of Bugworks.

Tackling viral infections

Elaborating further, he said: “Pandemics that caused millions of deaths on a global scale in the past 500 years have been either bacterial, like the black plague of the middle ages, or viral, like the Spanish flu during the first World War. Both these pandemics caused over 50 million deaths. The current Covid-19 pandemic is of viral origin, however since its primary site of infection is in the lungs, many deaths occur due to secondary bacterial infection, which are often drug-resistant.”

“A preferred response to such a viral infection would be a cocktail of potent antiviral, antibacterial and immune balancing agent. Unfortunately, we are somewhat handicapped in this treatment, which is the main reason for a large number deaths even in this age of modern medicine. We hope that with the current funding and global initiatives around Covid-19, we will get a potent antiviral in the coming years,” he added.

UTEC led the Bugworks Series A in 2018 and facilitated Bugworks’ collaboration with the Japanese ecosystem. “Bugworks has thoroughly impressed us with their scientific rigour, pre-clinical data, business development progress and commitment to saving lives. We are now proud to double-down our investment in Bugworks,” said Tomotaka Goji, Managing Partner & President, UTEC, in a statement.

“As witnessed with Covid-19, infectious diseases are threatening human existence. AMR is a serious issue and Global Brain regards this as a big unmet medical need. We are proud to partner with Bugworks to bring highly differentiated solutions in AMR to the market. We consider India to be an important region, both from innovation and market perspective and are hence accelerating our investment activity in India,” said Yasuhiko Yurimoto, founder, CEO and general partner, Global Brain.

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Economy

S&P/TSX composite up more than 100 points, U.S. stocks also higher

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TORONTO – Canada’s main stock index was up more than 100 points in late-morning trading, helped by strength in the base metal sector, while U.S. stock markets were also higher.

The S&P/TSX composite index was 143.00 points at 24,048.88.

In New York, the Dow Jones industrial average was up 174.22 points at 42,088.97. The S&P 500 index was up 10.23 points at 5,732.49, while the Nasdaq composite was up 30.02 points at 18,112.23.

The Canadian dollar traded for 74.23 cents US compared with 74.28 cents US on Wednesday.

The November crude oil contract was down US$1.68 at US$68.01 per barrel and the November natural gas contract was down six cents at US$2.75 per mmBTU.

The December gold contract was up US$4.40 at US$2,689.10 an ounce and the December copper contract was up 13 cents at US$4.62 a pound.

This report by The Canadian Press was first published Sept. 26, 2024.

Companies in this story: (TSX:GSPTSE, TSX:CADUSD)

The Canadian Press. All rights reserved.

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Investment

Tempted to switch to an online-only bank? Know the perks and drawbacks

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Switching to an online-only bank more than a decade ago was just another way Jessica Morgan was trying to save money at the time as a new grad.

“Saving money was the main motivator,” Morgan, now a financial educator and founder of Canadianbudget.ca, recalled.

“After graduating, you no longer qualify for student rates where you might get free banking and I didn’t want to go back to paying fees for giving the bank my money to hold.”

Digital lenders have grown in popularity in recent years, with more players popping up in the sector and traditional banks beefing up their online offerings. But some Canadians may still be hesitant to bank with a financial firm that doesn’t have physical branches where you can talk to an employee face-to-face.

Natasha Macmillan, director of everyday banking at Ratehub.ca, says some of that hesitancy to switch to an online lender is loyalty.

“There’s a large portion of Canadians who have had the same bank account for many years … they’re just hesitant to switch because it’s what they know.”

Tedious paperwork to switch banks can also discourage many Canadians from making the move despite the ease of opening online-only bank accounts, Macmillan added.

“There’s that aspect of you still need to sit down, do your research and then pick that online-only bank,” she said.

Data security concerns have also sowed seeds of doubt among many who are contemplating the switch, and prefer to continue to work with traditional banks with long-established reputations, Macmillan said.

Morgan said she often hears concerns from her clients — “What if I need help? Is this bank safe to use?” or more logistical questions, such as having access to an ATM or getting certified cheques.

One of the only major snags she personally recalls running into with her online lender was when she was purchasing a home.

“I needed to get a certified cheque, like, right away if I was going to put in an offer,” Morgan said. “You can get a certified cheque but it takes three days or so. They courier it to you.” She ended up going to her husband’s traditional bank to get day-of service.

Most online-only banks tend to offer banking products, such as savings accounts, with higher interest rates compared with traditional banks. Many also offer access to cash through any bank ATM without charge.

“Digital banks have generally a lower cost structure than a traditional bank and those savings will be passed on to the customer,” said Mahima Poddar, group head of personal banking at EQ Bank. For example, EQ offers a high-interest chequing account with no fees on everyday banking and unlimited transactions.

But customers should be aware they can’t deposit cash into their account and they can only withdraw bills, not coins.

“We don’t offer depositing of cash, but all of our research has shown that the use of cash is really diminishing,” Poddar said. “There are very few reasons why you need to urgently deposit.”

Customers also have to get used to doing all their banking by phone or through the company’s website or app.

Poddar added she thinks Canadians are more open to change, especially after the COVID-19 pandemic, which accelerated the need for better online banking services.

While trust in traditional institutions plays a strong role in choosing a bank, Poddar said EQ has the same level of protection and is governed by the same regulators as the big six banks in the country.

Lisa Brandt, 61, switched to online-only Manulife Bank more than five years ago. She says she has benefited from the move and has saved a lot of money over time on various banking fees.

“It puts me in the driver’s seat,” she said.

However, she did run into an issue once with depositing a cheque after she sold her home.

“If you’re going to deposit a couple hundred thousand dollars from a house sale, you’ll have to courier (the cheque) to them,” she said.

“It’s not quite as simple as walking into a branch and saying, ‘Give me my money.'”

While many online-only banks have been growing their consumer banking product offerings, traditional banks tend to have more financial product options, not only for individuals but also for small businesses.

“What we have heard from some Canadians is while they might be moving their chequing, savings and GIC accounts to those (online-only) spaces, they’re still maintaining a mortgage with the big players,” Macmillan said.

It’s not about moving all assets to one bank but weighing options on an individual basis, such as picking a bank with the lowest fee on a chequing account but moving investments to another bank for a better return, she explained.

“We’re starting to see that flexibility where people are shopping around for the best opportunity that can give them the most bang for their buck,” Macmillan said.

She added it is important for people to identify why they’re thinking of switching and find an online-only bank that aligns with their goals.

“It’s finding that happy medium where you do feel trust and security, that lower cost and fees and also the convenience and accessibility,” Macmillan said.

This report by The Canadian Press was first published Sept. 26, 2024.

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Economy

S&P/TSX composite up in late-morning trading, U.S. stocks also higher

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TORONTO – Strength in the energy and base metal stocks lifted Canada’s main stock index higher in late-morning trading, while U.S. stock markets also climbed higher.

The S&P/TSX composite index was up 78.80 points at 23,973.51.

In New York, the Dow Jones industrial average was up 89.81 points at 42,214.46. The S&P 500 index was up 2.55 points at 5,721.12, while the Nasdaq composite was up 21.24 points at 17,995.51.

The Canadian dollar traded for 74.24 cents US compared with 74.02 cents US on Monday.

The November crude oil contract was up US$1.06 at US$71.43 per barrel and the November natural gas contract was down two cents at US$2.83 per mmBTU.

The December gold contract was up US$18.10 at US$2,670.60 an ounce and the December copper contract was up 15 cents at US$4.49 a pound.

This report by The Canadian Press was first published Sept. 24, 2024.

Companies in this story: (TSX:GSPTSE, TSX:CADUSD)

The Canadian Press. All rights reserved.

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