Canadian manufacturers, supply chain gearing up for distribution of future COVID-19 vaccine - CTV News | Canada News Media
Connect with us

Business

Canadian manufacturers, supply chain gearing up for distribution of future COVID-19 vaccine – CTV News

Published

 on


TORONTO —
With a second large pharmaceutical company announcing promising trial results for a potential COVID-19 vaccine, Canadian companies are gearing up to pitch in to the logistical challenges of storing millions of doses in hyper-cold temperatures.

Guelph, Ont.-based Danby, maker of compact appliances such as fridges, freezers, microwaves, and air conditioners, will soon announce the production of a new line of -80 C freezers, company CEO and owner Jim Estill told CTVNews.ca in a phone interview.

He said the company is finalizing specifications and will officially announce the new line next week. He said full production will take about 120 days, “which is not out of line with the timing of the need.”  

Estill expects super-cold storage will be required in hospitals, pharmacies and courier hubs across Canada to handle an estimated 70 million vials of vaccines that require two doses for each recipient.

360 Medical, which provides cold storage equipment to labs, clinics, hospitals and pharmacies, is seeing a “massive increase in demand” for -80 C freezers, president Paul Greco told CTVNews.ca in a phone interview.

The Schomberg, Ont.-based distributer is fielding inquiries from doctor’s offices, hospitals and the Red Cross, he said.

The freezers range from about $8,500 to $20,000, but Greco says even small units can hold about 20,000 doses.

360 Medical’s supplier Haier Biomedical, which is based in China, has reassured that supply of hyper-cold storage equipment won’t be an issue, said Greco.

Moderna made headlines Monday with its reports that preliminary clinical trial data of its vaccine candidate show 94.5 per cent effectiveness in preventing COVID-19.

Last week, competitor Pfizer Inc. announced similar results for its vaccine candidate.

Both companies are developing what are called mRNA vaccines, a new technology that doesn’t include any of the coronavirus itself, but instead contains a piece of genetic code that trains the immune system to recognize the virus. Both need cold storage, but the requirements vary.

“mRNA vaccines are essentially brand new, but they are the vaccines of the future. The need now is for the coronavirus, but it will be used for other vaccines, too,” said Estill.

Moderna and Pfizer both said they would seek permission for emergency use from U.S. regulators within weeks.

The news provides some hope while COVID-19 cases surge in Canada, the U.S. and many parts of the world. But the challenge of producing and distributing a future vaccine to millions in this large country with a highly dispersed population looms large.

Never mind that every country in the world will be vying for vaccine supply at the same time.

Moderna president Dr. Stephen Hoge said Monday that “many vaccines” will be needed to meet global demand.

Canada has signed deals with seven vaccine developers, including Pfizer and Moderna, to reserve millions of doses of approved vaccines.

Purolator CEO John Ferguson said Canada has the necessary supply chain infrastructure in place to handle the challenge and his company is ready, too, to deliver a vaccine to hospitals, clinics, pharmacies, and long-term care facilities.

“We are used to shipping across Canada to every nook and cranny, every city, every suburb and every rural area,” he said in a phone interview from Toronto.

“This is on a big scale but I feel confident Canada is in good shape.”

Extreme cold storage will be required at central distribution hubs, where vaccine vials may stay for days or weeks. But during the “last mile” courier delivery that Purolator specializes in, temperatures can be maintained by ice packs, dry ice or other packaging, said Ferguson.

The distribution system is already in place to handle flu vaccines and other immunizations, along with a wide range of time-sensitive cancer therapeutics and other drugs, said Ferguson.

Distributing a COVID-19 vaccine will build on that experience, with Purolator adding dedicated workers, equipment and trucks.

“This is going to take governments, manufacturers and supply chain all pulling together to make sure this is done right.”

Danby, which has been in operation in Canada since 1947 and also owns a subsidiary in the United States, launched a medical refrigerator last year and has been ramping up its engineering since the emergence of COVID-19, said Estill.

“We are pulling out all the stops. It’s a top priority of the company,” said Estill, who has owned Danby since 2015.

“This can make a very meaningful impact in the world. A vaccine is no good if it can’t be distributed or stored.”

Danby has also pivoted into building ventilators in partnership with Canadian medical device maker Baylis Medical, and has built about 6,500 of an intended 10,000. The company has also donated 500 UV-light air purifiers to the Toronto District School Board.

An ongoing challenge of production geared to COVID-19 response is securing the necessary components, which are in short supply, said Estill.

Danby’s first hyper-cold freezer will be about 10 cubic feet, or roughly half the size of a large consumer chest freezer, and will cost C$10,000. That size will be easily shipped and will plug in to a normal wall outlet, said Estill, but future production will include a range of sizes.

“The complexity of building an -80 C freezer is massively huge. It’s not at all a simple freezer, but we make half a million freezers a year, so we can do it.”

To compare how cold that is, Health Canada recommends that home freezers be set at -18 C or lower to keep food safe. Dry ice, which is solid state carbon dioxide, also freezes to a temperature of -80 C. Touching items frozen at those temperatures with bare hands for more than a second or so can result in frostbite that could require hospital treatment.

Pfizer Canada spokesperson Christina Antoniou said in a statement provided to CTVNews.ca that the company is “working with urgency” with governments, and public health authorities to “determine the logistics of the vaccine distribution in Canada, pending regulatory approval.”

She said the company will manufacture a vaccine at multiple sites in the U.S. and Europe and will transport on a “just in time” system.

“For Canada, our distribution approach will be to largely ship from our manufacturing sites direct to the point of use.”

Pfizer will use dry ice in to maintain storage temperatures for up to 15 days, along with GPS-enabled thermal sensors in each “thermal shipper” that can be tracked at each stage of delivery.

“These GPS-enabled devices will allow Pfizer to proactively prevent unwanted deviations and act before they happen,” she wrote.

Depending on their formulation, vaccines could have different storage requirements.

Moderna says its COVID-19 vaccine candidate can be stored at normal refrigerator temperatures (2 C to 8 C) for up to 30 days and at -20 C for up to six months. It’s also stable at room temperature for up to 12 hours, company data has shown.

Pfizer’s candidate will require long-term deep freeze, says the company. That has led to a run on ultra-cold freezers in the U.S., but is raising concerns that rural hospitals won’t be able to afford the units, which cost up to US$15,000 each. 

Medical news site STAT says the Centers for Disease Control and Prevention has advised state health departments against purchasing ultra-cold freezers, with the idea that other vaccines with less demanding storage requirements will be available soon. 

Let’s block ads! (Why?)



Source link

Continue Reading

Business

Telus prioritizing ‘most important customers,’ avoiding ‘unprofitable’ offers: CFO

Published

 on

 

Telus Corp. says it is avoiding offering “unprofitable” discounts as fierce competition in the Canadian telecommunications sector shows no sign of slowing down.

The company said Friday it had fewer net new customers during its third quarter compared with the same time last year, as it copes with increasingly “aggressive marketing and promotional pricing” that is prompting more customers to switch providers.

Telus said it added 347,000 net new customers, down around 14.5 per cent compared with last year. The figure includes 130,000 mobile phone subscribers and 34,000 internet customers, down 30,000 and 3,000, respectively, year-over-year.

The company reported its mobile phone churn rate — a metric measuring subscribers who cancelled their services — was 1.09 per cent in the third quarter, up from 1.03 per cent in the third quarter of 2023. That included a postpaid mobile phone churn rate of 0.90 per cent in its latest quarter.

Telus said its focus is on customer retention through its “industry-leading service and network quality, along with successful promotions and bundled offerings.”

“The customers we have are the most important customers we can get,” said chief financial officer Doug French in an interview.

“We’ve, again, just continued to focus on what matters most to our customers, from a product and customer service perspective, while not loading unprofitable customers.”

Meanwhile, Telus reported its net income attributable to common shares more than doubled during its third quarter.

The telecommunications company said it earned $280 million, up 105.9 per cent from the same three-month period in 2023. Earnings per diluted share for the quarter ended Sept. 30 was 19 cents compared with nine cents a year earlier.

It reported adjusted net income was $413 million, up 10.7 per cent year-over-year from $373 million in the same quarter last year. Operating revenue and other income for the quarter was $5.1 billion, up 1.8 per cent from the previous year.

Mobile phone average revenue per user was $58.85 in the third quarter, a decrease of $2.09 or 3.4 per cent from a year ago. Telus said the drop was attributable to customers signing up for base rate plans with lower prices, along with a decline in overage and roaming revenues.

It said customers are increasingly adopting unlimited data and Canada-U.S. plans which provide higher and more stable ARPU on a monthly basis.

“In a tough operating environment and relative to peers, we view Q3 results that were in line to slightly better than forecast as the best of the bunch,” said RBC analyst Drew McReynolds in a note.

Scotiabank analyst Maher Yaghi added that “the telecom industry in Canada remains very challenging for all players, however, Telus has been able to face these pressures” and still deliver growth.

The Big 3 telecom providers — which also include Rogers Communications Inc. and BCE Inc. — have frequently stressed that the market has grown more competitive in recent years, especially after the closing of Quebecor Inc.’s purchase of Freedom Mobile in April 2023.

Hailed as a fourth national carrier, Quebecor has invested in enhancements to Freedom’s network while offering more affordable plans as part of a set of commitments it was mandated by Ottawa to agree to.

The cost of telephone services in September was down eight per cent compared with a year earlier, according to Statistics Canada’s most recent inflation report last month.

“I think competition has been and continues to be, I’d say, quite intense in Canada, and we’ve obviously had to just manage our business the way we see fit,” said French.

Asked how long that environment could last, he said that’s out of Telus’ hands.

“What I can control, though, is how we go to market and how we lead with our products,” he said.

“I think the conditions within the market will have to adjust accordingly over time. We’ve continued to focus on digitization, continued to bring our cost structure down to compete, irrespective of the price and the current market conditions.”

Still, Canada’s telecom regulator continues to warn providers about customers facing more charges on their cellphone and internet bills.

On Tuesday, CRTC vice-president of consumer, analytics and strategy Scott Hutton called on providers to ensure they clearly inform their customers of charges such as early cancellation fees.

That followed statements from the regulator in recent weeks cautioning against rising international roaming fees and “surprise” price increases being found on their bills.

Hutton said the CRTC plans to launch public consultations in the coming weeks that will focus “on ensuring that information is clear and consistent, making it easier to compare offers and switch services or providers.”

“The CRTC is concerned with recent trends, which suggest that Canadians may not be benefiting from the full protections of our codes,” he said.

“We will continue to monitor developments and will take further action if our codes are not being followed.”

French said any initiative to boost transparency is a step in the right direction.

“I can’t say we are perfect across the board, but what I can say is we are absolutely taking it under consideration and trying to be the best at communicating with our customers,” he said.

“I think everyone looking in the mirror would say there’s room for improvement.”

This report by The Canadian Press was first published Nov. 8, 2024.

Companies in this story: (TSX:T)

Source link

Continue Reading

Business

TC Energy cuts cost estimate for Southeast Gateway pipeline project in Mexico

Published

 on

 

CALGARY – TC Energy Corp. has lowered the estimated cost of its Southeast Gateway pipeline project in Mexico.

It says it now expects the project to cost between US$3.9 billion and US$4.1 billion compared with its original estimate of US$4.5 billion.

The change came as the company reported a third-quarter profit attributable to common shareholders of C$1.46 billion or $1.40 per share compared with a loss of C$197 million or 19 cents per share in the same quarter last year.

Revenue for the quarter ended Sept. 30 totalled C$4.08 billion, up from C$3.94 billion in the third quarter of 2023.

TC Energy says its comparable earnings for its latest quarter amounted to C$1.03 per share compared with C$1.00 per share a year earlier.

The average analyst estimate had been for a profit of 95 cents per share, according to LSEG Data & Analytics.

This report by The Canadian Press was first published Nov. 7, 2024.

Companies in this story: (TSX:TRP)

The Canadian Press. All rights reserved.

Source link

Continue Reading

Business

BCE reports Q3 loss on asset impairment charge, cuts revenue guidance

Published

 on

 

BCE Inc. reported a loss in its latest quarter as it recorded $2.11 billion in asset impairment charges, mainly related to Bell Media’s TV and radio properties.

The company says its net loss attributable to common shareholders amounted to $1.24 billion or $1.36 per share for the quarter ended Sept. 30 compared with a profit of $640 million or 70 cents per share a year earlier.

On an adjusted basis, BCE says it earned 75 cents per share in its latest quarter compared with an adjusted profit of 81 cents per share in the same quarter last year.

“Bell’s results for the third quarter demonstrate that we are disciplined in our pursuit of profitable growth in an intensely competitive environment,” BCE chief executive Mirko Bibic said in a statement.

“Our focus this quarter, and throughout 2024, has been to attract higher-margin subscribers and reduce costs to help offset short-term revenue impacts from sustained competitive pricing pressures, slow economic growth and a media advertising market that is in transition.”

Operating revenue for the quarter totalled $5.97 billion, down from $6.08 billion in its third quarter of 2023.

BCE also said it now expects its revenue for 2024 to fall about 1.5 per cent compared with earlier guidance for an increase of zero to four per cent.

The company says the change comes as it faces lower-than-anticipated wireless product revenue and sustained pressure on wireless prices.

BCE added 33,111 net postpaid mobile phone subscribers, down 76.8 per cent from the same period last year, which was the company’s second-best performance on the metric since 2010.

It says the drop was driven by higher customer churn — a measure of subscribers who cancelled their service — amid greater competitive activity and promotional offer intensity. BCE’s monthly churn rate for the category was 1.28 per cent, up from 1.1 per cent during its previous third quarter.

The company also saw 11.6 per cent fewer gross subscriber activations “due to more targeted promotional offers and mobile device discounting compared to last year.”

Bell’s wireless mobile phone average revenue per user was $58.26, down 3.4 per cent from $60.28 in the third quarter of the prior year.

This report by The Canadian Press was first published Nov. 7, 2024.

Companies in this story: (TSX:BCE)

The Canadian Press. All rights reserved.

Source link

Continue Reading

Trending

Exit mobile version