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Canadian military prepares to help with COVID-19 vaccine distribution – CTV News

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OTTAWA —
The Canadian military says it is making plans to play a role in the eventual rollout of COVID-19 vaccines nationwide.

As positive news about potential vaccines continues to make headlines, there are already military teams “fully integrated” with the Public Health Agency of Canada on planning for what’s set to be a herculean effort: getting vaccines into the arms of millions of Canadians once Health Canada approves them.

During a House of Commons National Defence Committee meeting on Monday, Canadian Armed Forces Strategic Joint Staff Director of Staff Major Gen. Trevor Cadieu said the military will play a role in that effort.

“We are working with optimism and enthusiasm as part of the COVID-19 vaccine rollout task force. Specifically, the Canadian Armed Forces is assisting with the development of a logistics support plan for the rollout of the vaccine,” Cadieu told MPs.

“We’re helping to establish a national operation centre that will oversee distribution of the vaccine,” he said. “That will be the command and control hub that will coordinate the distribution of a COVID-19 vaccine across the country.”

Cadieu said that Chief of the Defence Staff Gen. Jonathan Vance has dispatched some of his best planners to work on a logistic support plan that: “for all intents and purposes will be the maneuver plan to support the delivery of the vaccine across the country.”

It remains to be seen the degree of involvement the military will have, and whether it’ll be as extensive as it is in the United States. There, a general is leading the “Operation Warp Speed” effort and according to a recent 60 Minutes report, plans are in place to secure the stockpiles with armed guards.

“The chief of defence staff will be prepared to provide advice on how best to use Canadian Armed Forces resources for the actual rollout of the vaccine,” said Cadieu.

On his way in to a cabinet meeting on Monday afternoon, Treasury Board President Jean-Yves Duclos told reporters that once a vaccine, or vaccines are in-hand, the federal government will “use all the resources that Canadians can muster… including the discussions and actions with our armed forces.”

In the last week or so, two vaccine candidates from Pfizer and Moderna have shown high rates of effectiveness in preventing COVID-19 infections in clinical trials, and Prime Minister Justin Trudeau has said the federal government is gearing up for a potential rollout in early 2021.

“It’s not simply enough to have a vaccine discovered, not simply enough to have doses of the vaccines secured… We have to get them into people,” Trudeau said on Nov. 9.

In total, the federal government has allocated $1 billion to go towards vaccine procurement, and to-date has secured access to as many as 414 million doses of vaccine candidates from several producers: Medicago, AstraZeneca, Sanofi and GlaxoSmithKline, Johnson & Johnson, Novavax, Pfizer and Moderna.

HOW FAR FROM CANADIAN APPROVAL?

So far, no COVID-19 vaccine has been authorized safe for use in Canada. Health Canada will need to evaluate each candidate before it can be administered to Canadians.

“We need to see the data from the phase three trials,” said Dr. Caroline Quach-Thanh, chair of the National Advisory Committee on Immunization in an interview on CTV’s Power Play.

“We’re working in parallel to make sure that things move swiftly… so that when it gets approved, our recommendations will be almost ready so that we can start deployment,” she said.

As for how long it could take for Health Canada to approve a vaccine once the data is submitted, Dr. Quach-Thanh said that it depends on how robust the manufacturers’ submissions are. If there are holes, or questions outstanding for regulators, it could take some back and forth she said.

Quach-Thanh also noted that unlike the U.S., Canada does have a form of emergency use authorization to speed things up.

“I think it’s okay because then you know we’re sure that the data has been looked at carefully in terms of efficacy and safety, we don’t want anybody to be shortchanged,” she said.

FOUR-PRONGED PLAN, DETAILS SPARSE

To date, publicly available details around the plan to administer vaccines have been minimal. A number of the vaccine candidates being tested require two doses and must be stored at very cold temperatures, for example.

Last week, Public Services and Procurement Minister Anita Anand called Health Canada’s approval of an eventual vaccine or vaccines a “moving target” and said it was just one part of their four-pronged approach to vaccine deployment.

Anand said on Nov. 9 alongside Trudeau that preparations have been underway for months and that in terms of the involvement of the military, “all options are indeed on the table.”

“We are working always with the provinces and the territories to ensure a seamless distribution system is established,” Anand said at the time. “We are going to establish in a very complex environment an efficient and effective distribution system for these vaccines once they are approved.”

In addition to the needed regulatory approval, Canada needs to figure out how to biomanufacture elements of the vaccine, how to distribute those millions of vials, and how to oversee the on-the-ground administration of the vaccine.

In terms of biomanufacturing, Anand said that contracts have been signed to set up what are called “fill and finish” machines to mass-produce doses in Canada.

In terms of distribution, the contract tender for a national shipping plan has been issued and already 70 companies. including major cargo and airline brands. have expressed interest in playing a role. Part of the government’s criteria is to have the ability for cold storage to preserve the millions of doses coming our way, and the ability to deliver to all regions in Canada.

As for the administration of the vaccine, the government is procuring millions of syringes, vials, needles, alcohol swabs, gauze, and containers for discarded needles that will all be essential.

If the vaccine is a two-dose process, Chief Public Health Officer Dr. Theresa Tam has recently spoken about the need for some form of computer system to keep track who has been vaccinated and whether they’ve received both doses.

PRIORITIZATION AND GAPS

It’s expected that once a vaccine or vaccines are ready to be administered to Canadians, the initial supplies will be rationed and given to the highest-risk populations, such as seniors as well as health-care and essential workers.

According to the preliminary guidance issued by the National Advisory Committee on Immunization, prioritization will be based on three factors: the state of the pandemic when the vaccine is available; the supply available and number of doses required; and the risk-benefit analysis of key populations such as those who are at higher risk for adverse outcomes if they contract the novel coronavirus.

During Monday’s committee meeting, Canadian Armed Forces Surgeon Gen. Marc Bilodeau told MPs that “discussion is ongoing” as to where members of the military would fall in the order of precedence for getting immunized for COVID-19, and whether it will be mandatory for the military to be vaccinated.

As well, Quach-Thanh noted on Monday that not all sectors of the population will be able to access initial vaccines due to the lack of research into the potential impacts on them, such as children and people who are pregnant.

“It’s not that the vaccine is not made for children, it’s just that children have not been recruited in any of the trials and so we have no data on children, which is a little bit normal. When we study new drugs or new medication we always start with adults and when it’s safe and efficacious and adult then we go down to children just because that’s how it’s done. Same thing for pregnancy,” Quach-Thanh said.

She said it’s possible that Canada could be waiting between approved vaccines to have access to enough doses to give to everyone who wants to be vaccinated. That would be the case if the government is not able to secure additional doses of what would be a hotly in-demand effective vaccine.

“But, as we’re speaking, you know we’re expecting that it’s going to be rolled out over the next year or so, before everybody in Canada is vaccinated,” she said.

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STD epidemic slows as new syphilis and gonorrhea cases fall in US

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NEW YORK (AP) — The U.S. syphilis epidemic slowed dramatically last year, gonorrhea cases fell and chlamydia cases remained below prepandemic levels, according to federal data released Tuesday.

The numbers represented some good news about sexually transmitted diseases, which experienced some alarming increases in past years due to declining condom use, inadequate sex education, and reduced testing and treatment when the COVID-19 pandemic hit.

Last year, cases of the most infectious stages of syphilis fell 10% from the year before — the first substantial decline in more than two decades. Gonorrhea cases dropped 7%, marking a second straight year of decline and bringing the number below what it was in 2019.

“I’m encouraged, and it’s been a long time since I felt that way” about the nation’s epidemic of sexually transmitted infections, said the CDC’s Dr. Jonathan Mermin. “Something is working.”

More than 2.4 million cases of syphilis, gonorrhea and chlamydia were diagnosed and reported last year — 1.6 million cases of chlamydia, 600,000 of gonorrhea, and more than 209,000 of syphilis.

Syphilis is a particular concern. For centuries, it was a common but feared infection that could deform the body and end in death. New cases plummeted in the U.S. starting in the 1940s when infection-fighting antibiotics became widely available, and they trended down for a half century after that. By 2002, however, cases began rising again, with men who have sex with other men being disproportionately affected.

The new report found cases of syphilis in their early, most infectious stages dropped 13% among gay and bisexual men. It was the first such drop since the agency began reporting data for that group in the mid-2000s.

However, there was a 12% increase in the rate of cases of unknown- or later-stage syphilis — a reflection of people infected years ago.

Cases of syphilis in newborns, passed on from infected mothers, also rose. There were nearly 4,000 cases, including 279 stillbirths and infant deaths.

“This means pregnant women are not being tested often enough,” said Dr. Jeffrey Klausner, a professor of medicine at the University of Southern California.

What caused some of the STD trends to improve? Several experts say one contributor is the growing use of an antibiotic as a “morning-after pill.” Studies have shown that taking doxycycline within 72 hours of unprotected sex cuts the risk of developing syphilis, gonorrhea and chlamydia.

In June, the CDC started recommending doxycycline as a morning-after pill, specifically for gay and bisexual men and transgender women who recently had an STD diagnosis. But health departments and organizations in some cities had been giving the pills to people for a couple years.

Some experts believe that the 2022 mpox outbreak — which mainly hit gay and bisexual men — may have had a lingering effect on sexual behavior in 2023, or at least on people’s willingness to get tested when strange sores appeared.

Another factor may have been an increase in the number of health workers testing people for infections, doing contact tracing and connecting people to treatment. Congress gave $1.2 billion to expand the workforce over five years, including $600 million to states, cities and territories that get STD prevention funding from CDC.

Last year had the “most activity with that funding throughout the U.S.,” said David Harvey, executive director of the National Coalition of STD Directors.

However, Congress ended the funds early as a part of last year’s debt ceiling deal, cutting off $400 million. Some people already have lost their jobs, said a spokeswoman for Harvey’s organization.

Still, Harvey said he had reasons for optimism, including the growing use of doxycycline and a push for at-home STD test kits.

Also, there are reasons to think the next presidential administration could get behind STD prevention. In 2019, then-President Donald Trump announced a campaign to “eliminate” the U.S. HIV epidemic by 2030. (Federal health officials later clarified that the actual goal was a huge reduction in new infections — fewer than 3,000 a year.)

There were nearly 32,000 new HIV infections in 2022, the CDC estimates. But a boost in public health funding for HIV could also also help bring down other sexually transmitted infections, experts said.

“When the government puts in resources, puts in money, we see declines in STDs,” Klausner said.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

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World’s largest active volcano Mauna Loa showed telltale warning signs before erupting in 2022

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WASHINGTON (AP) — Scientists can’t know precisely when a volcano is about to erupt, but they can sometimes pick up telltale signs.

That happened two years ago with the world’s largest active volcano. About two months before Mauna Loa spewed rivers of glowing orange molten lava, geologists detected small earthquakes nearby and other signs, and they warned residents on Hawaii‘s Big Island.

Now a study of the volcano’s lava confirms their timeline for when the molten rock below was on the move.

“Volcanoes are tricky because we don’t get to watch directly what’s happening inside – we have to look for other signs,” said Erik Klemetti Gonzalez, a volcano expert at Denison University, who was not involved in the study.

Upswelling ground and increased earthquake activity near the volcano resulted from magma rising from lower levels of Earth’s crust to fill chambers beneath the volcano, said Kendra Lynn, a research geologist at the Hawaiian Volcano Observatory and co-author of a new study in Nature Communications.

When pressure was high enough, the magma broke through brittle surface rock and became lava – and the eruption began in late November 2022. Later, researchers collected samples of volcanic rock for analysis.

The chemical makeup of certain crystals within the lava indicated that around 70 days before the eruption, large quantities of molten rock had moved from around 1.9 miles (3 kilometers) to 3 miles (5 kilometers) under the summit to a mile (2 kilometers) or less beneath, the study found. This matched the timeline the geologists had observed with other signs.

The last time Mauna Loa erupted was in 1984. Most of the U.S. volcanoes that scientists consider to be active are found in Hawaii, Alaska and the West Coast.

Worldwide, around 585 volcanoes are considered active.

Scientists can’t predict eruptions, but they can make a “forecast,” said Ben Andrews, who heads the global volcano program at the Smithsonian Institution and who was not involved in the study.

Andrews compared volcano forecasts to weather forecasts – informed “probabilities” that an event will occur. And better data about the past behavior of specific volcanos can help researchers finetune forecasts of future activity, experts say.

(asterisk)We can look for similar patterns in the future and expect that there’s a higher probability of conditions for an eruption happening,” said Klemetti Gonzalez.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

The Canadian Press. All rights reserved.

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Waymo’s robotaxis now open to anyone who wants a driverless ride in Los Angeles

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Waymo on Tuesday opened its robotaxi service to anyone who wants a ride around Los Angeles, marking another milestone in the evolution of self-driving car technology since the company began as a secret project at Google 15 years ago.

The expansion comes eight months after Waymo began offering rides in Los Angeles to a limited group of passengers chosen from a waiting list that had ballooned to more than 300,000 people. Now, anyone with the Waymo One smartphone app will be able to request a ride around an 80-square-mile (129-square-kilometer) territory spanning the second largest U.S. city.

After Waymo received approval from California regulators to charge for rides 15 months ago, the company initially chose to launch its operations in San Francisco before offering a limited service in Los Angeles.

Before deciding to compete against conventional ride-hailing pioneers Uber and Lyft in California, Waymo unleashed its robotaxis in Phoenix in 2020 and has been steadily extending the reach of its service in that Arizona city ever since.

Driverless rides are proving to be more than just a novelty. Waymo says it now transports more than 50,000 weekly passengers in its robotaxis, a volume of business numbers that helped the company recently raise $5.6 billion from its corporate parent Alphabet and a list of other investors that included venture capital firm Andreesen Horowitz and financial management firm T. Rowe Price.

“Our service has matured quickly and our riders are embracing the many benefits of fully autonomous driving,” Waymo co-CEO Tekedra Mawakana said in a blog post.

Despite its inroads, Waymo is still believed to be losing money. Although Alphabet doesn’t disclose Waymo’s financial results, the robotaxi is a major part of an “Other Bets” division that had suffered an operating loss of $3.3 billion through the first nine months of this year, down from a setback of $4.2 billion at the same time last year.

But Waymo has come a long way since Google began working on self-driving cars in 2009 as part of project “Chauffeur.” Since its 2016 spinoff from Google, Waymo has established itself as the clear leader in a robotaxi industry that’s getting more congested.

Electric auto pioneer Tesla is aiming to launch a rival “Cybercab” service by 2026, although its CEO Elon Musk said he hopes the company can get the required regulatory clearances to operate in Texas and California by next year.

Tesla’s projected timeline for competing against Waymo has been met with skepticism because Musk has made unfulfilled promises about the company’s self-driving car technology for nearly a decade.

Meanwhile, Waymo’s robotaxis have driven more than 20 million fully autonomous miles and provided more than 2 million rides to passengers without encountering a serious accident that resulted in its operations being sidelined.

That safety record is a stark contrast to one of its early rivals, Cruise, a robotaxi service owned by General Motors. Cruise’s California license was suspended last year after one of its driverless cars in San Francisco dragged a jaywalking pedestrian who had been struck by a different car driven by a human.

Cruise is now trying to rebound by joining forces with Uber to make some of its services available next year in U.S. cities that still haven’t been announced. But Waymo also has forged a similar alliance with Uber to dispatch its robotaxi in Atlanta and Austin, Texas next year.

Another robotaxi service, Amazon’s Zoox, is hoping to begin offering driverless rides to the general public in Las Vegas at some point next year before also launching in San Francisco.

The Canadian Press. All rights reserved.

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