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Cause of grey hair may be ‘stuck’ cells, say scientists

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US scientists believe they may have uncovered why hair turns grey as we age, citing pigment-making cells which lose the ability to mature.

The arrested development impacts immature cells which would otherwise have developed into melanocytes which give hair its natural colour or shade.

The team from New York University (NYU) studied the process in mice, which have identical cells for fur colour.

They say the work could provide a basis for reversing the greying process.

According to the British Association of Dermatologists (BAD), work on melanocytes might also help our understanding and treatment of certain cancers and other medical conditions too.

How does hair turn grey?

We grow and shed hair all the time – it’s a normal cycle that happens throughout life.

New hair grows from hair follicles, found in the skin, where the pigment-producing melanocytes also reside.

Melanocytes continuously decay and renew too. New ones are made from stem cells and it’s these cells that the researchers believe become “stuck” in limbo in people whose hair has turned grey.

NYU Langone Health team used special scans and lab techniques to study the cell-ageing process.

As hair ages, sheds and then repeatedly grows back, increasing numbers of the melanocyte stem cells become sluggish at their job.

The stem cells stop roaming around the follicle and become fixed, thereby failing to mature into fully-fledged melanocytes. With no pigment being produced, the hair turns grey, white or silver.

“Our study adds to our basic understanding of how melanocyte stem cells work to colour hair,” study lead investigator Dr Qi Sun, a post-doctoral fellow at NYU Langone Health, told Nature journal.

“The newfound mechanisms raise the possibility that the same fixed-positioning of melanocyte stem cells may exist in humans. If so, it presents a potential pathway for reversing or preventing the greying.”

 

It is not the first time scientists have suggested that greying hair might be a partially reversible process.

Poor nutrition is one possible, treatable cause of premature greying.

Some researchers claim stress might contribute to human hair turning white, and have suggested removing anxiety might restore the pigmentation process – at least for a while.

Other research suggests genetics, or our DNA, partly determines when we go grey.

 

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While some prefer to hide grey hair with dye, others embrace it. Some even choose to get ahead of nature, and prematurely colour hair silver, white or grey.

According to Glamour Magazine, silver hair is “the spring hair colour trend that the cool girls are rocking”.

“We’ve spotted one shade, in particular, taking off. Oyster grey is the fresh, breezy, pearlescent colour trend that’s cropping up all over Instagram,” the article says.

One hairstylist, Luke Hersheson, recently told British Vogue: “At one point it was a big no-no to have grey hair, but now we don’t equate grey hair with being ‘old’ – so many people are doing it.

“Post-lockdown, there is a feeling of liberty – many got into a grey hair rut because they couldn’t see their colourists, but came out of the other side and actually enjoyed the change.”

Experts advise against plucking out ‘rogue’ grey hairs. It won’t stop the next one that grows from the same follicle from being grey. If you damage the hair follicle, it may be hard for new hair to grow, meaning you could be left with less hair or even bald patches.

Dr Leila Asfour from the British Association of Dermatologists told the BBC work on hair colour was big business: “The global hair colour market is projected to attain a value of $33.7bn by 2030. Clearly there’s a demand.

“The obvious implication of this research, when it comes to the general public, is that it means being one step closer to finding a way to reverse our grey hairs.

“But this study’s results help the medical field understand better other conditions where these stem cells may have a role – for example, understand the underlying nature of the deadliest skin cancer we treat called melanoma.”

It might help with a medical condition called alopecia areata too, where the immune system attacks the hair and causes it to fall out. Sometimes the hair grows back white in these patients, she explained.

And it could give more clues about vitiligo – a skin condition where patients develop white skin patches. Scientists have tried surgically placing hair follicles in the affected areas to help regenerate the colour from the pigment found in the hair follicle.

“More research is needed,” Dr Asfour says.

Dr Yusur Al-Nuaimi from the British Hair and Nail Society said scalp health was important for supporting good head hair growth, especially as we age.

“The recent study in mice adds to our understanding of the hair follicle and how the pigment-producing cells function. We are already discovering more about the potential of stem cell therapies for conditions including hair loss and studies such as this one, with new findings about the colour-producing cells, may lead to an array of future treatment options for our patients.”

 

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The body of a Ugandan Olympic athlete who was set on fire by her partner is received by family

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NAIROBI, Kenya (AP) — The body of Ugandan Olympic athlete Rebecca Cheptegei — who died after being set on fire by her partner in Kenya — was received Friday by family and anti-femicide crusaders, ahead of her burial a day later.

Cheptegei’s family met with dozens of activists Friday who had marched to the Moi Teaching and Referral Hospital’s morgue in the western city of Eldoret while chanting anti-femicide slogans.

She is the fourth female athlete to have been killed by her partner in Kenya in yet another case of gender-based violence in recent years.

Viola Cheptoo, the founder of Tirop Angels – an organization that was formed in honor of athlete Agnes Tirop, who was stabbed to death in 2021, said stakeholders need to ensure this is the last death of an athlete due to gender-based violence.

“We are here to say that enough is enough, we are tired of burying our sisters due to GBV,” she said.

It was a somber mood at the morgue as athletes and family members viewed Cheptegei’s body which sustained 80% of burns after she was doused with gasoline by her partner Dickson Ndiema. Ndiema sustained 30% burns on his body and later succumbed.

Ndiema and Cheptegei were said to have quarreled over a piece of land that the athlete bought in Kenya, according to a report filed by the local chief.

Cheptegei competed in the women’s marathon at the Paris Olympics less than a month before the attack. She finished in 44th place.

Cheptegei’s father, Joseph, said that the body will make a brief stop at their home in the Endebess area before proceeding to Bukwo in eastern Uganda for a night vigil and burial on Saturday.

“We are in the final part of giving my daughter the last respect,” a visibly distraught Joseph said.

He told reporters last week that Ndiema was stalking and threatening Cheptegei and the family had informed police.

Kenya’s high rates of violence against women have prompted marches by ordinary citizens in towns and cities this year.

Four in 10 women or an estimated 41% of dating or married Kenyan women have experienced physical or sexual violence perpetrated by their current or most recent partner, according to the Kenya Demographic and Health Survey 2022.

The Canadian Press. All rights reserved.

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The ancient jar smashed by a 4-year-old is back on display at an Israeli museum after repair

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TEL AVIV, Israel (AP) — A rare Bronze-Era jar accidentally smashed by a 4-year-old visiting a museum was back on display Wednesday after restoration experts were able to carefully piece the artifact back together.

Last month, a family from northern Israel was visiting the museum when their youngest son tipped over the jar, which smashed into pieces.

Alex Geller, the boy’s father, said his son — the youngest of three — is exceptionally curious, and that the moment he heard the crash, “please let that not be my child” was the first thought that raced through his head.

The jar has been on display at the Hecht Museum in Haifa for 35 years. It was one of the only containers of its size and from that period still complete when it was discovered.

The Bronze Age jar is one of many artifacts exhibited out in the open, part of the Hecht Museum’s vision of letting visitors explore history without glass barriers, said Inbal Rivlin, the director of the museum, which is associated with Haifa University in northern Israel.

It was likely used to hold wine or oil, and dates back to between 2200 and 1500 B.C.

Rivlin and the museum decided to turn the moment, which captured international attention, into a teaching moment, inviting the Geller family back for a special visit and hands-on activity to illustrate the restoration process.

Rivlin added that the incident provided a welcome distraction from the ongoing war in Gaza. “Well, he’s just a kid. So I think that somehow it touches the heart of the people in Israel and around the world,“ said Rivlin.

Roee Shafir, a restoration expert at the museum, said the repairs would be fairly simple, as the pieces were from a single, complete jar. Archaeologists often face the more daunting task of sifting through piles of shards from multiple objects and trying to piece them together.

Experts used 3D technology, hi-resolution videos, and special glue to painstakingly reconstruct the large jar.

Less than two weeks after it broke, the jar went back on display at the museum. The gluing process left small hairline cracks, and a few pieces are missing, but the jar’s impressive size remains.

The only noticeable difference in the exhibit was a new sign reading “please don’t touch.”

The Canadian Press. All rights reserved.

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B.C. sets up a panel on bear deaths, will review conservation officer training

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VICTORIA – The British Columbia government is partnering with a bear welfare group to reduce the number of bears being euthanized in the province.

Nicholas Scapillati, executive director of Grizzly Bear Foundation, said Monday that it comes after months-long discussions with the province on how to protect bears, with the goal to give the animals a “better and second chance at life in the wild.”

Scapillati said what’s exciting about the project is that the government is open to working with outside experts and the public.

“So, they’ll be working through Indigenous knowledge and scientific understanding, bringing in the latest techniques and training expertise from leading experts,” he said in an interview.

B.C. government data show conservation officers destroyed 603 black bears and 23 grizzly bears in 2023, while 154 black bears were killed by officers in the first six months of this year.

Scapillati said the group will publish a report with recommendations by next spring, while an independent oversight committee will be set up to review all bear encounters with conservation officers to provide advice to the government.

Environment Minister George Heyman said in a statement that they are looking for new ways to ensure conservation officers “have the trust of the communities they serve,” and the panel will make recommendations to enhance officer training and improve policies.

Lesley Fox, with the wildlife protection group The Fur-Bearers, said they’ve been calling for such a committee for decades.

“This move demonstrates the government is listening,” said Fox. “I suspect, because of the impending election, their listening skills are potentially a little sharper than they normally are.”

Fox said the partnership came from “a place of long frustration” as provincial conservation officers kill more than 500 black bears every year on average, and the public is “no longer tolerating this kind of approach.”

“I think that the conservation officer service and the B.C. government are aware they need to change, and certainly the public has been asking for it,” said Fox.

Fox said there’s a lot of optimism about the new partnership, but, as with any government, there will likely be a lot of red tape to get through.

“I think speed is going to be important, whether or not the committee has the ability to make change and make change relatively quickly without having to study an issue to death, ” said Fox.

This report by The Canadian Press was first published Sept. 9, 2024.

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