China spat may be threatening Canada's bid to get early access to leading COVID-19 vaccine: experts - Vermilion Standard | Canada News Media
Connect with us

Health

China spat may be threatening Canada's bid to get early access to leading COVID-19 vaccine: experts – Vermilion Standard

Published

 on


Samples of the vaccine candidate have not been approved for shipment to Canada by Chinese customs, one of the researchers confirmed Tuesday

Canada’s first big push for a COVID-19 vaccine may be falling victim to sour relations with Beijing, as Chinese officials continue to hold up a shipment of the drug needed to carry out promised human trials here.

CanSino Biologics of Tianjin, China signed an accord with the federal government in May to have its vaccine tested in Canada, a heavily promoted deal the government said could give Canadians early access to the serum.

But more two-and-a-half months later, the Canadian trials have yet to start, because scientists have nothing to study.

Samples of the vaccine candidate – already one of the world’s most advanced in terms of the trial process – have not been approved for shipment to Canada by Chinese customs, one of the researchers confirmed Tuesday.

David Mulroney, Canada’s ambassador to China from 2009 to 2012, said it’s hard to know why the delivery has been stalled, but he has his suspicions.

“It’s likely that the shipment is being delayed as part of China’s retaliation against Canada over the Meng (Wanzhou) arrest,” he said, referring to the Huawei Technologies CFO held in Vancouver on a U.S. extradition request.

“But it could also be due to the kind of sudden, unexplained delay that routinely happens when you’re dealing with China’s opaque and often uncooperative customs authorities,” Mulroney added. “Either way, it raises the question of why the NRC thought it was a good idea to work with a Chinese partner on such a sensitive project.”

Related

Prime Minister Justin Trudeau announced the agreement between CanSino – a company with extensive Canadian ties – and the National Research Council (NRC) in mid-May, calling it “encouraging news.”

Under the accord, the Canadian Centre for Vaccinology at Dalhousie University would hold a small Phase 1 safety trial, and possibly also Phase 2 and 3 trials. If approved by regulators, it could then be manufactured at an NRC facility in Montreal, making Canadians “among the first in the world to have access to a safe and effective vaccine against COVID-19,” the council has said.

Meanwhile, CanSino has conducted its own Phase 1 and 2 trials in China, and was the first developer to publish study results in a peer-reviewed journal. They indicate the vaccine is generally safe and prompts an immune response in most recipients.

Last month, the company’s co-founder said it was in talks with Russia, Brazil, Chile and Saudi Arabia to conduct Phase 3 trials, which determine whether the vaccine actually protects people against COVID-19 infection.

Back in Canada, “we are continuing to wait for the vaccine,” said Scott Halperin, the Dalhousie scientist heading Canada’s planned Phase-1 trial.

“All we know is that its awaiting customs clearance by the Chinese government for export,” he said. “We have not been able to obtain any projected time lines. Nothing much else I can say, other than we can start the trial as soon as we receive the vaccine.”

It raises the question of why the NRC thought it was a good idea to work with a Chinese partner on such a sensitive project

Asked if political issues might be involved, he said that was “an excellent question to pose to Global Affairs Canada.”

A spokesman for Foreign Affairs Minister François-Philippe Champagne could not be reached by deadline. Nic Defalco, an NRC spokesman, said the council continues to work with CanSino, but did not respond to questions about the reason for the customs delay, or whether geopolitics were involved.

Guy Saint-Jacques, another former Canadian ambassador to China, said Tuesday he does not know what’s behind the delay. But he said it “could well be part of the Chinese arsenal” in the dispute over Meng’s arrest.

In an apparent response to the executive’s detention, Beijing has already imprisoned Michael Kovrig, a Canadian ex-diplomat, and Michael Spavor, a Canadian businessman, under vague espionage charges; increased another Canadian’s drug-dealing sentence from jail to death; and blocked some agricultural imports from Canada.

“It might also be that China would prefer to ensure that any vaccine is developed in China first and not shared with a foreign country, especially Canada,” Saint-Jacques added.


Chinese vaccine maker CanSino Biologics’ sign is pictured on its building in Tianjin, China, Nov. 20, 2018.

Stringer/Reuters/File

The federal government has said it is also looking at pre-ordering other vaccines that are advanced in their testing but, unlike the U.S. and several European countries, has yet to do so. The NRC is also collaborating with a team at the University of Saskatchewan and U.S. company VBI Vaccines on their own coronavirus vaccines, noted Defalco.

The CanSino vaccine candidate – called Ad5-nCoV – uses a different, harmless virus as a delivery system. The “adenovirus” is modified to express part of the SARS-CoV-2 germ that causes COVID, which is meant to trigger the immune system to fend off the coronavirus.

Early studies have not been a total success, with dampened immune response in some people, likely because they’ve been exposed to the vaccine’s adenovirus backbone before and have antibodies that repel it.

For that reason, some experts have questioned Canada’s investment in the product. Others say none of the leading vaccine candidates are likely to be perfectly effective, and any vaccine is better than none.

• Email: tblackwell@postmedia.com | Twitter:

Let’s block ads! (Why?)



Source link

Continue Reading

Health

Canada to donate up to 200,000 vaccine doses to combat mpox outbreaks in Africa

Published

 on

 

The Canadian government says it will donate up to 200,000 vaccine doses to fight the mpox outbreak in Congo and other African countries.

It says the donated doses of Imvamune will come from Canada’s existing supply and will not affect the country’s preparedness for mpox cases in this country.

Minister of Health Mark Holland says the donation “will help to protect those in the most affected regions of Africa and will help prevent further spread of the virus.”

Dr. Madhukar Pai, Canada research chair in epidemiology and global health, says although the donation is welcome, it is a very small portion of the estimated 10 million vaccine doses needed to control the outbreak.

Vaccine donations from wealthier countries have only recently started arriving in Africa, almost a month after the World Health Organization declared the mpox outbreak a public health emergency of international concern.

A few days after the declaration in August, Global Affairs Canada announced a contribution of $1 million for mpox surveillance, diagnostic tools, research and community awareness in Africa.

On Thursday, the Africa Centres for Disease Control and Prevention said mpox is still on the rise and that testing rates are “insufficient” across the continent.

Jason Kindrachuk, Canada research chair in emerging viruses at the University of Manitoba, said donating vaccines, in addition to supporting surveillance and diagnostic tests, is “massively important.”

But Kindrachuk, who has worked on the ground in Congo during the epidemic, also said that the international response to the mpox outbreak is “better late than never (but) better never late.”

“It would have been fantastic for us globally to not be in this position by having provided doses a much, much longer time prior than when we are,” he said, noting that the outbreak of clade I mpox in Congo started in early 2023.

Clade II mpox, endemic in regions of West Africa, came to the world’s attention even earlier — in 2022 — as that strain of virus spread to other countries, including Canada.

Two doses are recommended for mpox vaccination, so the donation may only benefit 100,000 people, Pai said.

Pai questioned whether Canada is contributing enough, as the federal government hasn’t said what percentage of its mpox vaccine stockpile it is donating.

“Small donations are simply not going to help end this crisis. We need to show greater solidarity and support,” he said in an email.

“That is the biggest lesson from the COVID-19 pandemic — our collective safety is tied with that of other nations.”

This report by The Canadian Press was first published Sept. 13, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

The Canadian Press. All rights reserved.

Source link

Continue Reading

Health

How many Nova Scotians are on the doctor wait-list? Number hit 160,000 in June

Published

 on

 

HALIFAX – The Nova Scotia government says it could be months before it reveals how many people are on the wait-list for a family doctor.

The head of the province’s health authority told reporters Wednesday that the government won’t release updated data until the 160,000 people who were on the wait-list in June are contacted to verify whether they still need primary care.

Karen Oldfield said Nova Scotia Health is working on validating the primary care wait-list data before posting new numbers, and that work may take a matter of months. The most recent public wait-list figures are from June 1, when 160,234 people, or about 16 per cent of the population, were on it.

“It’s going to take time to make 160,000 calls,” Oldfield said. “We are not talking weeks, we are talking months.”

The interim CEO and president of Nova Scotia Health said people on the list are being asked where they live, whether they still need a family doctor, and to give an update on their health.

A spokesperson with the province’s Health Department says the government and its health authority are “working hard” to turn the wait-list registry into a useful tool, adding that the data will be shared once it is validated.

Nova Scotia’s NDP are calling on Premier Tim Houston to immediately release statistics on how many people are looking for a family doctor. On Tuesday, the NDP introduced a bill that would require the health minister to make the number public every month.

“It is unacceptable for the list to be more than three months out of date,” NDP Leader Claudia Chender said Tuesday.

Chender said releasing this data regularly is vital so Nova Scotians can track the government’s progress on its main 2021 campaign promise: fixing health care.

The number of people in need of a family doctor has more than doubled between the 2021 summer election campaign and June 2024. Since September 2021 about 300 doctors have been added to the provincial health system, the Health Department said.

“We’ll know if Tim Houston is keeping his 2021 election promise to fix health care when Nova Scotians are attached to primary care,” Chender said.

This report by The Canadian Press was first published Sept. 11, 2024.

The Canadian Press. All rights reserved.

Source link

Continue Reading

Health

Newfoundland and Labrador monitoring rise in whooping cough cases: medical officer

Published

 on

 

ST. JOHN’S, N.L. – Newfoundland and Labrador‘s chief medical officer is monitoring the rise of whooping cough infections across the province as cases of the highly contagious disease continue to grow across Canada.

Dr. Janice Fitzgerald says that so far this year, the province has recorded 230 confirmed cases of the vaccine-preventable respiratory tract infection, also known as pertussis.

Late last month, Quebec reported more than 11,000 cases during the same time period, while Ontario counted 470 cases, well above the five-year average of 98. In Quebec, the majority of patients are between the ages of 10 and 14.

Meanwhile, New Brunswick has declared a whooping cough outbreak across the province. A total of 141 cases were reported by last month, exceeding the five-year average of 34.

The disease can lead to severe complications among vulnerable populations including infants, who are at the highest risk of suffering from complications like pneumonia and seizures. Symptoms may start with a runny nose, mild fever and cough, then progress to severe coughing accompanied by a distinctive “whooping” sound during inhalation.

“The public, especially pregnant people and those in close contact with infants, are encouraged to be aware of symptoms related to pertussis and to ensure vaccinations are up to date,” Newfoundland and Labrador’s Health Department said in a statement.

Whooping cough can be treated with antibiotics, but vaccination is the most effective way to control the spread of the disease. As a result, the province has expanded immunization efforts this school year. While booster doses are already offered in Grade 9, the vaccine is now being offered to Grade 8 students as well.

Public health officials say whooping cough is a cyclical disease that increases every two to five or six years.

Meanwhile, New Brunswick’s acting chief medical officer of health expects the current case count to get worse before tapering off.

A rise in whooping cough cases has also been reported in the United States and elsewhere. The Pan American Health Organization issued an alert in July encouraging countries to ramp up their surveillance and vaccination coverage.

This report by The Canadian Press was first published Sept. 10, 2024.

The Canadian Press. All rights reserved.

Source link

Continue Reading

Trending

Exit mobile version