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China's coronavirus 'could share 89% of its DNA with Sars' – supporting the theory it started in bats – Yahoo Sports

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People wear masks in the Mass Transit Railway in Hong Kong, China. (May James/Echoes Wire/Barcroft Media via Getty Images)
<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="Since the new coronavirus emerged little over a month ago, experts have wondered where it came from and how deadly it could be.” data-reactid=”31″>Since the new coronavirus emerged little over a month ago, experts have wondered where it came from and how deadly it could be.

The first human to have caught the virus is thought to have done so at a seafood and live animal market in the Chinese city of Wuhan, capital of Hubei province.

Of the six coronavirus strains previously known to infect humans, the new one initially appeared most genetically similar to severe acute respiratory syndrome (Sars), which killed 774 people during its 2004 outbreak.

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="READ MORE: Coronavirus vaccine ‘will not be available until mid-2020’, pharma exec warns” data-reactid=”34″>READ MORE: Coronavirus vaccine ‘will not be available until mid-2020’, pharma exec warns

Scientists from Fudan University in Shanghai have since found it appears to be 89.1% genetically similar to “a group of Sars-like coronaviruses”.

With Sars having started in bats, this suggests the nocturnal creatures may also be responsible for the new coronavirus, which has killed at least 361 people in China so far.

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Security staff check on the temperature of students entering a university n Manila, Philippines, as public fear over the new Ccronavirus grows. (Ezra Acayan/Getty Images)

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="Authorities have confirmed 17,485 cases of the new coronavirus in mainland China alone, according to John Hopkins University.” data-reactid=”57″>Authorities have confirmed 17,485 cases of the new coronavirus in mainland China alone, according to John Hopkins University.

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="The Lancet journal has reported, however, that 75,000 people could have battled the infection just in Wuhan.” data-reactid=”58″>The Lancet journal has reported, however, that 75,000 people could have battled the infection just in Wuhan.

Most of those who initially became ill worked at or visited the market, which was promptly shut.

The Fudan scientists analysed one of the workers, a 41-year-old man who was admitted to hospital on 26 December after battling a fever, tight chest and cough for a week.

A “cluster” of patients were first reported to the World Health Organziation on 31 December.

A “lung sample” taken from the worker allowed the virus – called 2019-nCoV – to be genetically screened, revealing its similarity to Sars.

“The identification of multiple Sars-like-coronaviruses in bats led to the idea these animals act as the natural reservoir hosts of these viruses,” the scientists wrote in the journal Nature.

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="READ MORE: Coronavirus ‘may have infected seven times more people than reported” data-reactid=”64″>READ MORE: Coronavirus ‘may have infected seven times more people than reported

A team from the Chinese Academy of Sciences in Wuhan also analysed the viral DNA of five coronavirus patients.

They found the new strain seems to share 79.5% of its genetics with Sars.

Results, also published in Nature, further show the virus is 96% “identical” to a coronavirus that infects bats.

“These two scientific papers provide the formal evidence for what is already widely known,” said Professor Ian Jones of the University of Reading. 

“2019-nCoV is a bat virus and Sars is the closest relative seen previously in people. 

“In essence, it’s a version of Sars that spreads more easily but causes less damage. 

“The virus also uses the same receptor, the door used to get into human cells, which explains transmission and why it causes pneumonia. 

“Most encouragingly though, this indicates treatments and vaccines developed for Sars should work for the Wuhan virus.”

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="Scientists from Peking University in Beijing have previously traced&nbsp;2019-nCoV to snakes, namely the Chinese krait and cobra.” data-reactid=”75″>Scientists from Peking University in Beijing have previously traced 2019-nCoV to snakes, namely the Chinese krait and cobra.

They compared the DNA of the virus to that of other pathogens from various places and species.

Results suggested 2019-nCoV is a “combination of a coronavirus found in bats and another coronavirus of unknown origin”.

The virus is thought to contain a mix of proteins that bind to cell receptors, allowing it to enter and trigger disease.

The team found snakes that were likely the “intermediate host” between bats and humans, with the mix of proteins facilitating the species “jump”.

The masked palm civet, a mammal native to the Indian subcontinent and south-east Asia, was an intermediate host for Sars between bats and humans.

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="READ MORE: WHO declares coronavirus a ‘global health emergency’” data-reactid=”81″>READ MORE: WHO declares coronavirus a ‘global health emergency’

Another coronavirus strain is Middle East respiratory syndrome (Mers), which killed 858 during its 2012 outbreak.

Mers is also thought to have originated in bats, with camels being the intermediate host.

Not all experts are convinced by the role of snakes in 2019-nCoV’s outbreak, however.

Speaking when the Peking University results were released, Professor Paul Hunter of the University of East Anglia said: “It is still not known with certainty and it may never be definitively proved.

“There are initial, although contested, reports the virus has already been detected in both bats and snakes, and the strains in both bats and snakes are similar to each other, and to the strains from human cases.

“There is still much more to find out about the virus and there is a real possibility the exact origin may not be found.

“The big question is no longer where it came from, but how and where it is spreading in human populations.”

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="Coronaviruses are “RNA viruses”, which means they “mutate all the time”, Yahoo UK reported.” data-reactid=”93″>Coronaviruses are “RNA viruses”, which means they “mutate all the time”, Yahoo UK reported.

In simple terms, RNA is a “precursor” to the more well-known DNA.

Exposure to live animals at the market likely enabled the virus to “jump” from its origin species into humans.

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A woman wears a face mask in Manila, Philippines. (Ezra Acayan/Getty Images)

Like all coronaviruses, the new strain initially causes flu-like symptoms.

China’s National Health Commission confirmed the virus can spread person-to-person, via sneezing, coughing or shaking contaminated hands.

In the most severe cases, victims are succumbing to pneumonia.

This comes about when a respiratory infection causes the alveoli (air sacs) in the lungs to become inflamed and filled with fluid or pus, according to the American Lung Association.

The lungs then struggle to draw in air, resulting in reduced oxygen in the bloodstream.

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="“Without treatment the end is inevitable,”&nbsp;said the charity Médecins Sans Frontières.” data-reactid=”122″>“Without treatment the end is inevitable,” said the charity Médecins Sans Frontières.

“Deaths occurs because of asphyxiation.”

Pneumonia is usually caused by bacteria, which tend to respond to antibiotics.

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="When a virus is to blame, pneumonia may be treated via “antiviral medication”, according to the&nbsp;American Lung Association.” data-reactid=”125″>When a virus is to blame, pneumonia may be treated via “antiviral medication”, according to the American Lung Association.

<p class="canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm" type="text" content="The US Centers for Disease Control and Prevention&nbsp;have warned&nbsp;there is no specific treatment for coronaviruses.” data-reactid=”126″>The US Centers for Disease Control and Prevention have warned there is no specific treatment for coronaviruses.

Professor Peter Horby from the University of Oxford added there is “no effective anti-viral” at the moment, with treatment being “supportive”.

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Canada to donate up to 200,000 vaccine doses to combat mpox outbreaks in Africa

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The Canadian government says it will donate up to 200,000 vaccine doses to fight the mpox outbreak in Congo and other African countries.

It says the donated doses of Imvamune will come from Canada’s existing supply and will not affect the country’s preparedness for mpox cases in this country.

Minister of Health Mark Holland says the donation “will help to protect those in the most affected regions of Africa and will help prevent further spread of the virus.”

Dr. Madhukar Pai, Canada research chair in epidemiology and global health, says although the donation is welcome, it is a very small portion of the estimated 10 million vaccine doses needed to control the outbreak.

Vaccine donations from wealthier countries have only recently started arriving in Africa, almost a month after the World Health Organization declared the mpox outbreak a public health emergency of international concern.

A few days after the declaration in August, Global Affairs Canada announced a contribution of $1 million for mpox surveillance, diagnostic tools, research and community awareness in Africa.

On Thursday, the Africa Centres for Disease Control and Prevention said mpox is still on the rise and that testing rates are “insufficient” across the continent.

Jason Kindrachuk, Canada research chair in emerging viruses at the University of Manitoba, said donating vaccines, in addition to supporting surveillance and diagnostic tests, is “massively important.”

But Kindrachuk, who has worked on the ground in Congo during the epidemic, also said that the international response to the mpox outbreak is “better late than never (but) better never late.”

“It would have been fantastic for us globally to not be in this position by having provided doses a much, much longer time prior than when we are,” he said, noting that the outbreak of clade I mpox in Congo started in early 2023.

Clade II mpox, endemic in regions of West Africa, came to the world’s attention even earlier — in 2022 — as that strain of virus spread to other countries, including Canada.

Two doses are recommended for mpox vaccination, so the donation may only benefit 100,000 people, Pai said.

Pai questioned whether Canada is contributing enough, as the federal government hasn’t said what percentage of its mpox vaccine stockpile it is donating.

“Small donations are simply not going to help end this crisis. We need to show greater solidarity and support,” he said in an email.

“That is the biggest lesson from the COVID-19 pandemic — our collective safety is tied with that of other nations.”

This report by The Canadian Press was first published Sept. 13, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

The Canadian Press. All rights reserved.

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How many Nova Scotians are on the doctor wait-list? Number hit 160,000 in June

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HALIFAX – The Nova Scotia government says it could be months before it reveals how many people are on the wait-list for a family doctor.

The head of the province’s health authority told reporters Wednesday that the government won’t release updated data until the 160,000 people who were on the wait-list in June are contacted to verify whether they still need primary care.

Karen Oldfield said Nova Scotia Health is working on validating the primary care wait-list data before posting new numbers, and that work may take a matter of months. The most recent public wait-list figures are from June 1, when 160,234 people, or about 16 per cent of the population, were on it.

“It’s going to take time to make 160,000 calls,” Oldfield said. “We are not talking weeks, we are talking months.”

The interim CEO and president of Nova Scotia Health said people on the list are being asked where they live, whether they still need a family doctor, and to give an update on their health.

A spokesperson with the province’s Health Department says the government and its health authority are “working hard” to turn the wait-list registry into a useful tool, adding that the data will be shared once it is validated.

Nova Scotia’s NDP are calling on Premier Tim Houston to immediately release statistics on how many people are looking for a family doctor. On Tuesday, the NDP introduced a bill that would require the health minister to make the number public every month.

“It is unacceptable for the list to be more than three months out of date,” NDP Leader Claudia Chender said Tuesday.

Chender said releasing this data regularly is vital so Nova Scotians can track the government’s progress on its main 2021 campaign promise: fixing health care.

The number of people in need of a family doctor has more than doubled between the 2021 summer election campaign and June 2024. Since September 2021 about 300 doctors have been added to the provincial health system, the Health Department said.

“We’ll know if Tim Houston is keeping his 2021 election promise to fix health care when Nova Scotians are attached to primary care,” Chender said.

This report by The Canadian Press was first published Sept. 11, 2024.

The Canadian Press. All rights reserved.

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Newfoundland and Labrador monitoring rise in whooping cough cases: medical officer

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ST. JOHN’S, N.L. – Newfoundland and Labrador‘s chief medical officer is monitoring the rise of whooping cough infections across the province as cases of the highly contagious disease continue to grow across Canada.

Dr. Janice Fitzgerald says that so far this year, the province has recorded 230 confirmed cases of the vaccine-preventable respiratory tract infection, also known as pertussis.

Late last month, Quebec reported more than 11,000 cases during the same time period, while Ontario counted 470 cases, well above the five-year average of 98. In Quebec, the majority of patients are between the ages of 10 and 14.

Meanwhile, New Brunswick has declared a whooping cough outbreak across the province. A total of 141 cases were reported by last month, exceeding the five-year average of 34.

The disease can lead to severe complications among vulnerable populations including infants, who are at the highest risk of suffering from complications like pneumonia and seizures. Symptoms may start with a runny nose, mild fever and cough, then progress to severe coughing accompanied by a distinctive “whooping” sound during inhalation.

“The public, especially pregnant people and those in close contact with infants, are encouraged to be aware of symptoms related to pertussis and to ensure vaccinations are up to date,” Newfoundland and Labrador’s Health Department said in a statement.

Whooping cough can be treated with antibiotics, but vaccination is the most effective way to control the spread of the disease. As a result, the province has expanded immunization efforts this school year. While booster doses are already offered in Grade 9, the vaccine is now being offered to Grade 8 students as well.

Public health officials say whooping cough is a cyclical disease that increases every two to five or six years.

Meanwhile, New Brunswick’s acting chief medical officer of health expects the current case count to get worse before tapering off.

A rise in whooping cough cases has also been reported in the United States and elsewhere. The Pan American Health Organization issued an alert in July encouraging countries to ramp up their surveillance and vaccination coverage.

This report by The Canadian Press was first published Sept. 10, 2024.

The Canadian Press. All rights reserved.

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