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COVID-related diabetes may be temporary; racial disparities widen with Omicron infections

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The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that has yet to be certified by peer review.

COVID-related diabetes may be temporary

Patients with severe COVID-19 who develop diabetes while hospitalized may have only a temporary form of the disease and their blood sugar levels may return to normal afterward, according to new findings.

Researchers studied 594 patients who showed signs of diabetes while hospitalized for COVID-19, including 78 with no previous diagnosis of diabetes. Compared to patients with pre-existing diabetes, many of the newly diagnosed patients had less severe blood sugar issues but more serious COVID-19. Roughly a year after leaving the hospital, 40% of the newly diagnosed patients had gone back to blood sugar levels below the cutoff for diabetes, researchers reported in the Journal of Diabetes and Its Complications. “This suggests to us that newly diagnosed diabetes may be a transitory condition related to the acute stress of COVID-19 infection,” study coauthor Dr. Sara Cromer of the Massachusetts General Hospital in Boston said in a statement.

“Our results suggest that … insulin deficiency, if it occurs at all, is generally not permanent,” Cromer said. “These patients may only need insulin or other medications for a short time, and it’s therefore critical that physicians closely follow them to see if and when their conditions improve.”

COVID-19 racial disparities widen with Omicron

New data illustrate the jumps in U.S. coronavirus infection rates caused by the Omicron variant and the heavier toll it has taken on minorities in the latest example of racial disparity in the pandemic.

Overall, for every 2,000 people in the United States, roughly one per day caught a first-time infection when the Delta variant was dominant, compared to about 8 to 10 per day in January after Omicron took over, researchers found. Racial disparities further widened with Omicron, the researchers reported on Tuesday on medRxiv https:// ahead of peer review. During the Delta period, the infection rate in Black patients was 1.3 to 1.4 times higher than for white patients. With Omicron, it jumped to 3 to 4 times higher. The Delta infection rate of 1.6 to 1.8 times higher in Hispanics versus non-Hispanics grew to 3 times higher with Omicron. Children were also hit hard by Omicron infections. The rate in January was highest in children under age 5, at 22 a day per 2,000 in that age-group.

The findings were drawn from 733,509 Delta infections and 147,964 Omicron cases. Omicron was associated with significantly lower rates of emergency department visits, hospitalizations, intensive care unit admissions, and need for mechanical ventilation. However, emergency department visits and need for intensive care was higher among Blacks and Hispanics. The researchers noted that the study subjects might not be representative of all U.S. patients.

Cancer treatments do not impair COVID-19 survival

Powerful cancer therapies do not increase the risk of death for cancer patients with COVID-19, according to research based on data from the UK Coronavirus Cancer Monitoring Project.

Researchers looked at 2,515 adults with COVID-19 who were receiving – or had recently received – systemic cancer treatments such as chemotherapy, immunotherapy, hormonal therapy, or certain targeted drugs. Within a week after COVID-19 diagnosis, 38% of the patients had died. Half the patients in the study were older than 72. Overall, patients with lung cancer or blood cancers were at higher risk for death. Chemotherapy, however, did not affect patients’ risk of death from the virus, and immunotherapy actually improved the odds of survival, according to a report published on Monday in JAMA Network Open.

Earlier studies of COVID-19 patients have found that those with cancer have poorer outcomes, but that may be due to “age, sex, comorbidities, and cancer subtype rather than anticancer treatments,” the research team concluded.

 

For a Reuters graphic on vaccines in development:

 

(Reporting by Nancy Lapid; Editing by Bill Berkrot)

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Some Ontario docs now offering RSV shot to infants with Quebec rollout set for Nov.

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Some Ontario doctors have started offering a free shot that can protect babies from respiratory syncytial virus while Quebec will begin its immunization program next month.

The new shot called Nirsevimab gives babies antibodies that provide passive immunity to RSV, a major cause of serious lower respiratory tract infections for infants and seniors, which can cause bronchiolitis or pneumonia.

Ontario’s ministry of health says the shot is already available at some doctor’s offices in Ontario with the province’s remaining supply set to arrive by the end of the month.

Quebec will begin administering the shots on Nov. 4 to babies born in hospitals and delivery centers.

Parents in Quebec with babies under six months or those who are older but more vulnerable to infection can also book immunization appointments online.

The injection will be available in Nunavut and Yukon this fall and winter, though administration start dates have not yet been announced.

This report by The Canadian Press was first published Oct. 21, 2024.

-With files from Nicole Ireland

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

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Polio is rising in Pakistan ahead of a new vaccination campaign

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ISLAMABAD (AP) — Polio cases are rising ahead of a new vaccination campaign in Pakistan, where violence targeting health workers and the police protecting them has hampered years of efforts toward making the country polio-free.

Since January, health officials have confirmed 39 new polio cases in Pakistan, compared to only six last year, said Anwarul Haq of the National Emergency Operation Center for Polio Eradication.

The new nationwide drive starts Oct. 28 with the aim to vaccinate at least 32 million children. “The whole purpose of these campaigns is to achieve the target of making Pakistan a polio-free state,” he said.

Pakistan regularly launches campaigns against polio despite attacks on the workers and police assigned to the inoculation drives. Militants falsely claim the vaccination campaigns are a Western conspiracy to sterilize children.

Most of the new polio cases were reported in the southwestern Balochistan and southern Sindh province, following by Khyber Pakhtunkhwa province and eastern Punjab province.

The locations are worrying authorities since previous cases were from the restive northwest bordering Afghanistan, where the Taliban government in September suddenly stopped a door-to-door vaccination campaign.

Afghanistan and Pakistan are the two countries in which the spread of the potentially fatal, paralyzing disease has never been stopped. Authorities in Pakistan have said that the Taliban’s decision will have major repercussions beyond the Afghan border, as people from both sides frequently travel to each other’s country.

The World Health Organization has confirmed 18 polio cases in Afghanistan this year, all but two in the south of the country. That’s up from six cases in 2023. Afghanistan used a house-to-house vaccination strategy this June for the first time in five years, a tactic that helped to reach the majority of children targeted, according to WHO.

Health officials in Pakistan say they want the both sides to conduct anti-polio drives simultaneously.

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White House says health insurance needs to fully cover condoms, other over-the-counter birth control

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WASHINGTON (AP) — Millions of people with private health insurance would be able to pick up over-the-counter methods like condoms, the “morning after” pill and birth control pills for free under a new rule the White House proposed on Monday.

Right now, health insurers must cover the cost of prescribed contraception, including prescription birth control or even condoms that doctors have issued a prescription for. But the new rule would expand that coverage, allowing millions of people on private health insurance to pick up free condoms, birth control pills, or “morning after” pills from local storefronts without a prescription.

The proposal comes days before Election Day, as Vice President Kamala Harris affixes her presidential campaign to a promise of expanding women’s health care access in the wake of the U.S. Supreme Court’s decision to undo nationwide abortion rights two years ago. Harris has sought to craft a distinct contrast from her Republican challenger, Donald Trump, who appointed some of the judges who issued that ruling.

“The proposed rule we announce today would expand access to birth control at no additional cost for millions of consumers,” Health and Human Services Secretary Xavier Becerra said in a statement. “Bottom line: women should have control over their personal health care decisions. And issuers and providers have an obligation to comply with the law.”

The emergency contraceptives that people on private insurance would be able to access without costs include levonorgestrel, a pill that needs to be taken immediately after sex to prevent pregnancy and is more commonly known by the brand name “Plan B.”

Without a doctor’s prescription, women may pay as much as $50 for a pack of the pills. And women who delay buying the medication in order to get a doctor’s prescription could jeopardize the pill’s effectiveness, since it is most likely to prevent a pregnancy within 72 hours after sex.

If implemented, the new rule would also require insurers to fully bear the cost of the once-a-day Opill, a new over-the-counter birth control pill that the U.S. Food and Drug Administration approved last year. A one-month supply of the pills costs $20.

Federal mandates for private health insurance to cover contraceptive care were first introduced with the Affordable Care Act, which required plans to pick up the cost of FDA-approved birth control that had been prescribed by a doctor as a preventative service.

The proposed rule would not impact those on Medicaid, the insurance program for the poorest Americans. States are largely left to design their own rules around Medicaid coverage for contraception, and few cover over-the-counter methods like Plan B or condoms.

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