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Covid Vaccine Does Not Increase Pre-Term Birth Risk, Says Study – NDTV

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One barrier to vaccine acceptance is the concern that it might disrupt pregnancy

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COVID-19 vaccination during pregnancy is not associated with complications such as preterm birth or smaller than normal weight of babies, according to a study.

The researchers at the Yale University in the US noted that pregnant people who contract COVID-19 have an increased risk of disease severity and death.

One barrier to vaccine acceptance is the concern that vaccination might disrupt pregnancy, they said.

The findings, published on Tuesday in a report by the US Centers for Disease Control and Prevention (CDC), is based on more than 40,000 pregnant individuals.

It shows that COVID-19 vaccination during pregnancy was not associated with preterm birth or small-for-gestational-age (SGA) when comparing vaccinated with unvaccinated pregnant people.

The trimester when the vaccination was received and the number of COVID-19 vaccine doses received were also not associated with increased risk of preterm birth or SGA, the researchers found.

“Getting vaccinated against COVID-19 is important for preventing severe illness in pregnant people,” said Heather Lipkind, associate professor at the Yale School of Medicine and lead author of the study.

Preterm birth — where babies are delivered earlier than 37 weeks — and SG, in which babies are delivered smaller in size than normal for the gestational age, have been associated with a higher risk for infant death and disability.

The researchers used data from eight health care organisations to investigate the risk for preterm birth or SGA among vaccinated and unvaccinated pregnant women aged 16 to 49 years.

Among those included in the study, 10,064 individuals, or nearly 22 per cent, received at least one COVID-19 vaccine dose during pregnancy, researchers said.

As many as 98.3 per cent received vaccination during their second or third trimester while rest received it during their first trimester of pregnancy.

Almost 96 per cent of those vaccinated received an mRNA vaccine developed by Pfizer or Moderna.

The new findings add to the evidence that COVID-19 vaccination is safe during pregnancy, the researchers said.

Research into the drivers behind low vaccine acceptance among pregnant people has found that the most common concerns have been a lack of information about COVID-19 vaccine safety in pregnant people and potential harm to the foetus, they added.

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RCMP warn about benzodiazepine-laced fentanyl tied to overdose in Alberta – Edmonton Journal

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Grande Prairie RCMP issued a warning Friday after it was revealed fentanyl linked to a deadly overdose was mixed with a chemical that doesn’t respond to naloxone treatment.

The drugs were initially seized on Feb. 28 after a fatal overdose, and this week, Health Canada reported back to Mounties that the fentanyl had been mixed with Bromazolam, which is a benzodiazepine.

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Mounties say this is the first recorded instance of Bromazolam in Alberta. The drug has previously been linked to nine fatal overdoses in New Brunswick in 2022.

The pills seized in Alberta were oval-shaped and stamped with “20” and “SS,” though Mounties say it can come in other forms.

Naloxone treatment, given in many cases of opioid toxicity, is not effective in reversing the effects of Bromazalam, Mounties said, and therefore, any fentanyl mixed with the benzodiazepine “would see a reduced effectiveness of naloxone, requiring the use of additional doses and may still result in a fatality.”

Photo of benzodiazepine-laced fentanyl seized earlier this year by Grande Prairie RCMP after a fatal overdose. edm

From January to November of last year, there were 1,706 opioid-related deaths in Alberta, and 57 linked to benzodiazepine, up from 1,375 and 43, respectively, in 2022.

Mounties say officers responded to about 1,100 opioid-related calls for service, last year with a third of those proving fatal. RCMP officers also used naloxone 67 times while in the field, a jump of nearly a third over the previous year.

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CFIA continues surveillance for HPAI in cattle, while sticking with original name for disease – RealAgriculture

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The Canada Food Inspection Agency will continue to refer to highly pathogenic avian influenza in cattle as HPAI in cattle, and not refer to it as bovine influenza A virus (BIAV), as suggested by the American Association of Bovine Practitioners earlier this month.

Dr. Martin Appelt, senior director for the Canadian Food Inspection Agency, in the interview below, says at this time Canada will stick with “HPAI in cattle” when referencing the disease that’s been confirmed in dairy cattle in multiple states in the U.S.

The CFIA’s naming policy is consistent with the agency’s U.S. counterparts’, as the U.S. Animal and Plant Health Inspection Service has also said it will continue referring to it as HPAI or H5N1.

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Appelt explains how the CFIA is learning from the U.S. experience to-date, and how it is working with veterinarians across Canada to stay vigilant for signs of the disease in dairy and beef cattle.

As of April 19, there has not been a confirmed case of HPAI in cattle in Canada. Appelt says it’s too soon to say if an eventual positive case will significantly restrict animal movement, as is the case with positive poultry cases.

This is a major concern for the cattle industry, as beef cattle especially move north and south across the U.S. border by the thousands. Appelt says that CFIA will address an infection in each species differently in conjunction with how the disease is spread and the threat to neighbouring farms or livestock.

Currently, provincial dairy organizations have advised producers to postpone any non-essential tours of dairy barns, as a precaution, in addition to other biosecurity measures to reduce the risk of cattle contracting HPAI.

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Toronto reports 2 more measles cases. Use our tool to check the spread in Canada – Toronto Star

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Canada has seen a concerning rise in measles cases in the first months of 2024.

By the third week of March, the country had already recorded more than three times the number of cases as all of last year. Canada had just 12 cases of measles in 2023, up from three in 2022.

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