Connect with us

Health

Doctors seeing resistance to blood transfusions over unfounded COVID vaccine concerns

Published

 on

Alberta physicians are raising the alarm about a dangerous trend — fuelled by misinformation — that could cost lives.

Dr. Stephanie Cooper, an obstetrician specializing in high-risk births at Foothills Medical Centre, said a patient recently refused to consent to a blood transfusion if it came from a donor who had received the COVID-19 vaccine.

“I see people with severe hemorrhage due to childbirth on a regular basis. And for me, the idea that this is out there is somewhat mind-boggling.”

It came up in a routine conversation while she was counselling the patient before a C-section. The patient did not end up needing a blood transfusion.

Genius Dog 336 x 280 - Animated

Shocked by what she’d encountered, Cooper shared her experience on Twitter and was inundated with responses, including from other health-care providers who reached out with similar stories.

“I’m quite concerned about it,” she said, noting Canada’s blood supply does not register the COVID vaccination status of donors.

“There isn’t a choice to receive COVID vaccine-negative blood. So by declining blood, it means you will die.”

Parents request unvaccinated blood

This is not an isolated incident in Alberta.

“We’re seeing it about once or twice a month, at this stage. And the worry is of course that these requests might increase,” said Dr. Dave Sidhu, the southern Alberta medical lead for transfusion and transplant medicine.

That includes parents of sick children.

“We do see a few, certainly in our bone marrow transplant patients in particular. You have to remember these kiddos are immuno-compromised and there’s always more sensitivity around these patients, and some of them can be quite frail,” said Sidhu, who is also an associate professor in the Cumming School of Medicine at the University of Calgary.

“Any caution or questions around that, we encourage our parents to ask.”

Dr. Dave Sidhu, the head of transfusion and transplant medicine in southern Alberta, says he’s been involved in cases where parents request blood from unvaccinated donors for their sick children. (Submitted by Dave Sidhu)

According to Sidhu, requests for so-called directed blood donations, taken from an unvaccinated parent or legal guardian, come with a number of risks and have not been accommodated.

So far, parents have agreed to proceed after he’s talked with them, he said.

And while some adults have ultimately refused blood transfusions, doctors were able to treat them in other ways.

“The real worry is situations where blood is needed and it is life and limb,” he said.

“There is currently no medical or scientific evidence to suggest that there are changes in people’s genetic composition due to these mRNA vaccines or any other issues with safety around blood from either vaccinated or unvaccinated donors.”

Internalized misinformation

According to Timothy Caulfield, a Canada Research Chair in Health Law and Policy at the University of Alberta, these situations are becoming increasingly common.

“It’s happening not just in Canada but really all over the world.… This is a really good example of a behaviour — of a request — that is the direct result of the spread of misinformation,” he said.

“This is based on the idea that either the blood is contaminated, the blood is going to give them COVID, that they believe the risks associated with the COVID vaccines are going to have some adverse impact on them. So basically they’ve embraced and internalized the misinformation associated with the COVID vaccines and fear the blood as a result of that.”

Caulfield said competent adults have the right to refuse treatment even if the decision could harm them.

“This really highlights, I think, how powerful misinformation can be. It can really have an impact in a way that can be dangerous,” he said.

“There is no evidence to support these concerns.”

Tim Caulfield, Canadian author and Canada Research Chair in Health Law and Policy at the University of Alberta, says refusing blood transfusions from people who are vaccinated against COVID-19 is dangerous and highlights the power of misinformation. (Submitted by Tim Caulfield)

Canadian Blood Services, which has an entire page on its website dedicated to this issue, said the health of patients is its top priority.

“Health Canada has not recommended or imposed any restriction on the use of the approved COVID-19 vaccines and blood donation,” a spokesperson said in a statement emailed to CBC News.

“This is because the blood of donors who have received non-live vaccines does not pose a risk to patients who receive a blood transfusion.”

On its website, Canadian Blood Services explains non-live vaccines “do not contain infectious bacteria or virus or other pathogens that can replicate in the vaccine recipient or cause an infection.”

Other such vaccines, including those protecting against tetanus, whooping cough and influenza, do not impact eligibility to donate blood.

Dr. Stephanie Cooper, a high-risk obstetrician at Foothills Hospital, is worried more patients will start refusing blood transfusions, sparking legal and ethical concerns for physicians. (Submitted by Dr. Stephanie Cooper)

It also addresses concerns vaccine-generated spike proteins, in an immunized donor, could be harmful to those receiving their blood.

“These claims are unproven and not substantiated by the safety studies required for regulatory approval of these vaccines, or from ongoing Canadian and international vaccine and blood safety monitoring,” the website states.

Meanwhile, David Evans, a professor in the department of medical microbiology and immunology at the University of Alberta, believes improving scientific literacy may be the best way, in the long run, to combat the wave of misinformation that is leading to these potentially life-threatening decisions.

“The reality is these vaccines have an incredibly good safety record,” he said.

“Maybe we should start looking at our biology curriculum and starting to ask, ‘what are we teaching our kids, what do we want them to know by the time they get out of Grade 12 about the way our biology works?’ Just enough to help you put into perspective what we’re talking about when something like this comes along.”

Source link

Continue Reading

Health

Flu shots are now free for everyone in Quebec due to overwhelmed hospital ERs

Published

 on

 

While the campaign for flu shots has already been underway in Quebec for several weeks, the provincial government announced on Friday that immunization will now be free of charge for any Quebecer over the age of six months.

Previously, only people who met certain criteria (babies, seniors, the chronically ill, etc) were able to get the influenza immunization free of charge, and the vaccination sites set up for COVID-19 were only handling free flu shots. Meanwhile, the general population in Quebec was previously only able to get vaccinated at pharmacies, for a fee.

The decision was made due to the critical state of hospital ERs in the province, particularly at children’s hospitals in Montreal, where kids are being brought in by parents in larger numbers than usual due to rising rates of flu, COVID-19 and RSV infections.

Genius Dog 336 x 280 - Animated

“With the trio of viruses currently circulating, the influenza vaccine is now available free of charge to all Quebecers who wish to take advantage of it. It’s one more tool to limit the pressure on our network.”

—Quebec Health Minister Christian Dubé

To schedule an appointment for a flu shot and/or a COVID-19 shot, please visit the Clic Santé website.

Source link

Continue Reading

Health

Deadly Bird Flu Outbreak Is The Worst In U.S. History

Published

 on

An ongoing outbreak of a deadly strain of bird flu has now killed more birds than any past flare-up in U.S. history.

The virus, known as highly pathogenic avian influenza, has led to the deaths of 50.54 million domestic birds in the country this year, according to Agriculture Department data reported by Reuters on Thursday. That figure represents birds like chickens, ducks and turkeys from commercial poultry farms, backyard flocks and facilities such as petting zoos.

The count surpasses the previous record of 50.5 million dead birds from a 2015 outbreak, according to Reuters.

Separately, USDA data shows at least 3,700 confirmed cases among wild birds.

Genius Dog 336 x 280 - Animated
Turkeys in a barn on a poultry farm.
Turkeys in a barn on a poultry farm.

Turkeys in a barn on a poultry farm.

On farms, some birds die from the flu directly, while in other cases, farmers kill their entire flocks to prevent the virus from spreading after one bird tests positive. Such farmers have occasionally drawn condemnation from animal welfare advocates for using a culling method known as “ventilation shutdown plus,” which involves sealing off the airways to a barn and pumping in heat to kill the animals.

The virus has raged through Europe and North America since 2021. A variety of wild birds have been affected worldwide, including bald eagles, vultures and seabirds. This month, Peru reported its first apparent outbreak of highly pathogenic avian influenza after 200 dead pelicans were found on a beach.

Pelicans suspected to have died from highly pathogenic avian influenza are seen on a beach in Lima, Peru, on Nov. 24.Pelicans suspected to have died from highly pathogenic avian influenza are seen on a beach in Lima, Peru, on Nov. 24.
Pelicans suspected to have died from highly pathogenic avian influenza are seen on a beach in Lima, Peru, on Nov. 24.

Pelicans suspected to have died from highly pathogenic avian influenza are seen on a beach in Lima, Peru, on Nov. 24.

The migration of infected wild birds has been a major cause of the spread. Health and wildlife officials urge anyone who keeps domestic birds to prevent contact with their wild counterparts.

While health experts do not generally consider highly pathogenic avian influenza to be a major risk to mammals, a black bear cub in Alaska was euthanized earlier this month after contracting the virus. Wildlife veterinarian Dr. Kimberlee Beckmen told the Juneau Empire newspaper that the young cub had a weak immune system.

Over the summer, avian flu also spread among seals in Maine, which the National Oceanic and Atmospheric Administration believed contributed to an unusually high number of seal deaths.

The Centers for Disease Control and Prevention states that the risk “to the general public” from the bird flu outbreak is low. However, the agency recommends precautions like wearing personal protective equipment and thoroughly washing hands for people who have prolonged contact with birds that may be infected.

In April, a Colorado prisoner working at a commercial farm became the first person in the U.S. to test positive for the new strain, though he was largely asymptomatic.

Source link

Continue Reading

Health

Successful tests in animal models pave way for strategy for universal flu vaccine

Published

 on

 

An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus provided broad protection from otherwise lethal flu strains in initial tests, according to a study.

This could serve one day as a general preventative measure against future flu pandemics, the researchers from University of Pennsylvania, US, said.

According to the study, tests in animal models showed that the vaccine dramatically reduced signs of illness and protected from death, even when the animals were exposed to flu strains different from those used in making the vaccine.

Genius Dog 336 x 280 - Animated

The “multivalent” vaccine, which the researchers described in a paper published in the journal Science, used the same messenger ribonucleic acid (mRNA) technology employed in the Pfizer and Moderna SARS-CoV-2 vaccines, the study said.

This mRNA technology that enabled those Covid-19 vaccines was pioneered at Penn, the study said.

“The idea here is to have a vaccine that will give people a baseline level of immune memory to diverse flu strains, so that there will be far less disease and death when the next flu pandemic occurs,” said study senior author Scott Hensley.

Influenza viruses periodically cause pandemics with enormous death tolls. The best known of these was the 1918-19 “Spanish flu” pandemic, which killed at least tens of millions of people worldwide.

Flu viruses can circulate in birds, pigs, and other animals, and pandemics can start when one of these strains jumps to humans and acquires mutations that adapt it better for spreading among humans.

Current flu vaccines are merely “seasonal” vaccines that protect against recently circulating strains, but would not be expected to protect against new, pandemic strains. The strategy employed by the Penn researchers is to vaccinate using immunogens – a type of antigen that stimulates immune responses – from all known influenza subtypes in order to elicit broad protection, the study said.

The vaccine is not expected to provide “sterilizing” immunity that completely prevents viral infections. Instead, the new study showed that the vaccine elicited a memory immune response that can be quickly recalled and adapted to new pandemic viral strains, significantly reducing severe illness and death from infections.

“It would be comparable to first-generation SARS-CoV-2 mRNA vaccines, which were targeted to the original Wuhan strain of the coronavirus.

“Against later variants such as Omicron, these original vaccines did not fully block viral infections, but they continue to provide durable protection against severe disease and death,” said Hensley.

The experimental vaccine, when injected and taken up by the cells of recipients, started producing copies of a key flu virus protein, the hemagglutinin protein, for all twenty influenza hemagglutinin subtypes—H1 through H18 for influenza A viruses, and two more for influenza B viruses.

“For a conventional vaccine, immunizing against all these subtypes would be a major challenge, but with mRNA technology it’s relatively easy,” Hensley said.

In mice, the mRNA vaccine elicited high levels of antibodies, which stayed elevated for at least four months, and reacted strongly to all 20 flu subtypes. Moreover, the vaccine seemed relatively unaffected by prior influenza virus exposures, which can skew immune responses to conventional influenza vaccines.

The researchers observed that the antibody response in the mice was strong and broad, whether or not the animals had been exposed to flu virus before.

Hensley and his colleagues currently are designing human clinical trials, he said. The researchers envision that, if those trials are successful, the vaccine may be useful for eliciting long-term immune memory against all influenza subtypes in people of all age groups, including young children.

“We think this vaccine could significantly reduce the chances of ever getting a severe flu infection,” Hensley said.

In principle, he added, the same multivalent mRNA strategy can be used for other viruses with pandemic potential, including coronaviruses.

Source link

Continue Reading

Trending