A Manitoba mother says a routine appointment for her and her three-year-old to get flu shots ended in frustration and mixed messages after they were each mistakenly given an adult dose of a COVID-19 vaccine.
Jenna Bardarson is calling for policy changes at the province’s vaccination centres to make sure that doesn’t happen to another family.
The shots were administered on Nov. 24 at the Keystone Centre in Brandon.
Bardarson says that shortly after she and her daughter, Dali, got their shots, the health worker who had given them excused herself to speak with a supervisor. When the worker returned, she told them she had made a mistake and given them both the adult Pfizer-BioNTech vaccine.
“I was shocked. I didn’t know what to say. My immediate concerns were, of course, would my daughter be OK and also who could I speak to about this,” Bardarson said in online social media messages Friday to The Canadian Press.
Once she got home, Bardarson made multiple calls to different departments with the regional medical authority, hoping to speak with someone about the error and her concerns, she said.
She said no one was able to provide her with the answers or information she needed. “The conversations with various Prairie Mountain Health members have been frustrating, to say the least.”
Bardarson said she already had two doses of a COVID-19 vaccine and was due for her booster shot next month. Her daughter is too young to be eligible.
Health Canada last month approved a pediatric version of the Pfizer shot for children ages five to 11, but it has not yet approved a vaccine for those under five.
Bardarson said she and her daughter had headaches and sore arms the following day. Her daughter had no appetite and was throwing up.
Manitoba Health confirmed the mistake in a statement and said staff from Prairie Mountain have reached out to the mother to discuss what happened as well as to provide an update on an investigation.
“Patient safety is a critical aspect of all health-care services in Manitoba. We are constantly reviewing our processes to ensure that our systems support our staff in preventing errors,” it said.
“In this case … our team reviewed the existing processes to make adjustments that would help avoid a similar error from occurring in the future.”
Bardarson said the health region has not provided her with updated information on the investigation and would not discuss any consequences the health worker may have faced.
Manitoba Health said no further action would be taken against the worker, because she immediately recognized the error and told a supervisor.
For Bardarson, that’s not enough.
“I by no means want her fired; however, there should be some sort of measures in place for harm reduction.”
Bardarson suggested taking away the worker’s injection privileges or enhanced supervision during vaccinations.
She said she would also like to see areas at vaccination centres separated by vaccine types, instead of having different vaccines offered in the same booth.
Manitoba Health could not say if others have been given a COVID-19 vaccine by mistake, but acknowledged that medication errors, although rare, do occur. It added that Bardarson was provided with information about the risks of the COVID-19 vaccine, which in this case it says are low.
Health Canada said it is not in charge of immunization monitoring and could not comment on whether similar mistakes have occurred in other parts of the country.
– Brittany Hobson, The Canadian Press
Mexican president has cardiac catheterization, health said to be good
Mexican President Andres Manuel Lopez Obrador underwent a cardiac catheterization in hospital on Friday and was found to be in good health, the interior ministry said in a statement.
“In this procedure, the heart and the arteries of the president were found to be healthy and functioning appropriately,” the statement said.
Lopez Obrador, 68, who had a serious heart attack in 2013 and recently recovered from his second coronavirus infection, underwent the procedure as part of a check-up every six months that include lab tests, electrocardiograms, stress tests and CT scans, the government said.
The medical team said the latest results indicated the need for a cardiac catheterization, without providing further details on why they performed what they described as a 30-minute procedure.
The government said “no other type of intervention” was needed and that Lopez Obrador was in “perfect health.”
The procedure inserts a thin tube into a large blood vessel leading to the heart and can detect how well the heart is working.
Lopez Obrador said he had mild symptoms from both bouts of COVID-19. In the most recent case earlier this month, he went into isolation for a week before returning to public activities, including lengthy daily news conferences.
On his first day back, he praised honey, pain reliever paracetamol and VapoRub, a topical ointment popular in Mexico, for helping ease his symptoms.
(Reporting by Daina Beth Solomon, Dave Graham and Miguel Angel Gutierrez; Editing by William Mallard)
Small children getting less sick from Omicron; Genetic mutation protects against severe COVID
The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that has yet to be certified by peer review.
Small children are getting less sick from Omicron
In very young children, the Omicron variant of the coronavirus causes less severe disease than the Delta variant, according to a new study.
Researchers reviewed data on nearly 80,000 U.S. children under age 5 with a first infection, including 7,201 infected in late December or early January when Omicron was causing more than 90% of cases. After accounting for other risk factors, including medical conditions and socioeconomic circumstances, researchers found children infected during the Omicron surge had a 29% lower risk of emergency department visits, a 67% lower risk of hospitalization, a 68% lower risk of needing intensive care, and a 71% lower risk of needing machines to breathe, compared to children infected with Delta. However, “because of Omicron’s increased transmissibility, the overall number of emergency department visits, hospitalizations, ICU admissions, and mechanical ventilator use in children may still be greater” with Omicron than with Delta, according to a report posted on medRxiv ahead of peer review.
The investigators have also observed that infection rates were disproportionately higher in Black and Hispanic children for both Omicron and Delta for this age group, and the gap widened for infections with Omicron, said study leader Rong Xu of Case Western Reserve University School of Medicine. Not yet published data shows that “children under 5 had the highest infection rate with Omicron” compared to older children and adults in all age groups, she said.
Genetic mutation protects against severe COVID-19
New findings add to evidence that people with a certain version of a gene are less likely to develop severe COVID-19.
Earlier research had identified a specific group of genes, called the OAS1/2/3 gene cluster, as being involved in the risk for severe COVID-19. One version of a gene in that cluster – passed down from Neanderthals – appeared to protect against severe disease, reducing the risk by about 23%. The earlier research was done mainly in people of European ancestry. According to a report published in Nature Genetics, researchers now see the same association of this genetic variant with less severe COVID-19 in people of African ancestry.
“The fact that individuals of African descent had the same protection allowed us to identify the unique variant in the DNA that actually protects from COVID-19 infection,” coauthor Dr. Jennifer Huffman of said in a statement. OAS genes are involved in a cascade of effects that help cells fight viruses, the researchers said. Understanding of these genes and their effect on COVID-19 risks could aid development of future drugs, they added.
Fewer Delta breakthroughs with Moderna vs Pfizer/BioNTech
When the Delta variant of the coronavirus was prevalent in the United States, recipients of two doses of Moderna’s mRNA vaccine were less likely to experience a breakthrough infection – and if they did, were slightly less likely to be hospitalized – than recipients of two doses of the mRNA vaccine from Pfizer and BioNTech, a large study found.
Researchers analyzed health records of more than 637,000 vaccine recipients who were not previously infected with the virus and had not gotten a booster shot. As reported on Thursday in JAMA, breakthrough infections steadily increased every month from July to November 2021, with higher rates in the Pfizer/BioNTech group. In November, there were 2.8 cases among every thousand people vaccinated with the Pfizer/BioNTech shots, compared to 1.6 cases per thousand recipients of the Moderna vaccines. The vaccines protected equally well against death, but the hospitalization rate was 12.7% for infected Moderna recipients and 13.3% for Pfizer/BioNTech recipients. When the researchers compared 62,584 Moderna recipients to a closely-matched equal-sized group of Pfizer/BioNTech recipients, the risk for breakthrough infection was 15% lower in the Moderna group.
“Although there is a difference in breakthrough infections, both vaccines are highly protective against SARS-COV2 infection and especially against the most severe consequences of infection,” said coauthor Pamela Davis of Case Western Reserve University School of Medicine in a statement.
Click for a Reuters graphic on vaccines in development.
(Reporting by Nancy Lapid; Editing by Bill Berkrot)
FDA expands use of remdesivir to patients with high risk of hospitalization
The U.S. health regulator on Friday expanded its approval for the use of Gilead Sciences’ antiviral drug remdesivir to treat non-hospitalized patients 12 years and older for the treatment of mild-to-moderate COVID-19 disease with high risk of hospitalization.
Previously, the use of Veklury was limited to patients requiring hospitalization.
(Reporting by Leroy Leo in Bengaluru; editing by Diane Craft)
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