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Investing just $40 million new dollars in lung cancer research related to women has dramatic impact on US economy – Medical Xpress

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Doubling the funding for research focused on women and lung cancer will have enormous economic impacts for families and the nation, according to a new report released today by Women’s Health Access Matters (WHAM), which commissioned The RAND Corporation to create this study on lung cancer in women. According to rigorous modeling based on a number of conservative estimates, even health improvements of 0.1 percent in mortality and quality of life will yield a return on investment of $1,200 for every additional dollar spent. Today’s findings mirror three previous studies from WHAM, which were executed by The RAND Corporation and show similar findings with respect to the power of investment for women’s health research associated with Alzheimer’s disease, heart disease and rheumatoid arthritis.

For , this is particularly critical because in the U.S., lung is the number one cause of cancer death in . More women die of lung cancer (estimated approximately 61,000 in 2022, according to CA: A Cancer Journal for Clinicians) than of breast, ovarian and cervical cancers combined. And non-smoking women are more than two times as likely to get lung cancer as their male counterparts, yet the sex disparities of the disease have yet to be thoroughly examined, and only 15 percent of lung cancer research is focused on women.

Lung cancer research receives the least amount of funding of the major cancers affecting women. The new report is a first-of-its-kind microsimulation model that examines socioeconomic impacts of investments in women’s in the U.S.—revealing critical gaps in the nation’s current research portfolio and the potential gain to the economy through greater funding.

The new research examines the return on investment if the for women and lung cancer were doubled. Assuming that the additional research generates health improvements of only 0.1 percent or less in terms of age incidence, mortality and quality of life, the nation can reliably anticipate the following payoff:

  • For the U.S. population aged 25 and older, more than 22,700 years can be saved across 30 years of extended life, with substantial gains in health-related quality of life.
  • Approximately 2,500 more labor years (valued at $45 million in labor productivity) result from increased work time and longer life.

Overall, doubling the investment would have an expected ROI of more than 1,200 percent.

“These findings are stunning,” said WHAM Founder and CEO Carolee Lee. “Women are sick and dying from a disease that disproportionately affects them, yet research doesn’t acknowledge this fact. And the pain of disease is not just a medical problem by any means. This new data could not be more clear about the economic pain we all pay when women leave the workforce early to manage their own health or serve as caregivers for their loved ones. Women’s health is an economic issue that impacts everyone, and we can’t afford to ignore it.”

“This research shows that very small investments in women’s health can generate outsized returns, in part because women’s health research is still very much under-funded,” said Lori Frank, senior author of the study. “Our modeling suggests that even small investments in women’s lung cancer research could result in significant gains in , health-related and workforce productivity. But it also points to the importance of addressing diseases that hit women harder; equity in medical research leads to meaningful benefits.”

“This report brings important new data to the case that we have been making for years: that lung cancer impacts women differently—both physically and societally—and these disparities must be addressed,” said Laurie Fenton Ambrose, President and CEO of GO2 for Lung Cancer and supporter of the report. “The WHAM findings not only underscore the need for legislation that expands resources to better understand the science of lung cancer in women, but also show how investing in research could result in for women living with the disease.”

The WHAM Report can be a tool to help decisionmakers plan for future research strategies, help funders decide how to allocate their portfolios, and address the for payers and business leaders to invest in women’s health.

The report authors recommend expanding the research agenda to address multiple aspects of sex and gender in lung cancer using the limited evidence base, including:

  • The unknown interactions of sex and gender with lung cancer etiology, and to inform treatment and prevention research.
  • Understudied interactions of gender and race with lung cancer risk, health care and disease progression; in particular, examining obstacles to access to and use of diagnostic technology, including for personalized medicine.
  • Differences by sex and gender in lifestyle impacts on disease.
  • Differences in course and outcomes by sex and gender, based on different patterns of the use of formal and informal caregiving.

“Women are more than half of the population and workforce, control 60 percent of personal wealth, and are responsible for 85 percent of consumer spending and 80 percent of healthcare decisions,” said Lee. “Yet even while diseases impact them disproportionately and differently, pulling many from the workforce too soon, investment in women’s health research lags. This is such an easy win for our country.”

More information:
Report: thewhamreport.org/report/lung/

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Canada to donate up to 200,000 vaccine doses to combat mpox outbreaks in Africa

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The Canadian government says it will donate up to 200,000 vaccine doses to fight the mpox outbreak in Congo and other African countries.

It says the donated doses of Imvamune will come from Canada’s existing supply and will not affect the country’s preparedness for mpox cases in this country.

Minister of Health Mark Holland says the donation “will help to protect those in the most affected regions of Africa and will help prevent further spread of the virus.”

Dr. Madhukar Pai, Canada research chair in epidemiology and global health, says although the donation is welcome, it is a very small portion of the estimated 10 million vaccine doses needed to control the outbreak.

Vaccine donations from wealthier countries have only recently started arriving in Africa, almost a month after the World Health Organization declared the mpox outbreak a public health emergency of international concern.

A few days after the declaration in August, Global Affairs Canada announced a contribution of $1 million for mpox surveillance, diagnostic tools, research and community awareness in Africa.

On Thursday, the Africa Centres for Disease Control and Prevention said mpox is still on the rise and that testing rates are “insufficient” across the continent.

Jason Kindrachuk, Canada research chair in emerging viruses at the University of Manitoba, said donating vaccines, in addition to supporting surveillance and diagnostic tests, is “massively important.”

But Kindrachuk, who has worked on the ground in Congo during the epidemic, also said that the international response to the mpox outbreak is “better late than never (but) better never late.”

“It would have been fantastic for us globally to not be in this position by having provided doses a much, much longer time prior than when we are,” he said, noting that the outbreak of clade I mpox in Congo started in early 2023.

Clade II mpox, endemic in regions of West Africa, came to the world’s attention even earlier — in 2022 — as that strain of virus spread to other countries, including Canada.

Two doses are recommended for mpox vaccination, so the donation may only benefit 100,000 people, Pai said.

Pai questioned whether Canada is contributing enough, as the federal government hasn’t said what percentage of its mpox vaccine stockpile it is donating.

“Small donations are simply not going to help end this crisis. We need to show greater solidarity and support,” he said in an email.

“That is the biggest lesson from the COVID-19 pandemic — our collective safety is tied with that of other nations.”

This report by The Canadian Press was first published Sept. 13, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

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How many Nova Scotians are on the doctor wait-list? Number hit 160,000 in June

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HALIFAX – The Nova Scotia government says it could be months before it reveals how many people are on the wait-list for a family doctor.

The head of the province’s health authority told reporters Wednesday that the government won’t release updated data until the 160,000 people who were on the wait-list in June are contacted to verify whether they still need primary care.

Karen Oldfield said Nova Scotia Health is working on validating the primary care wait-list data before posting new numbers, and that work may take a matter of months. The most recent public wait-list figures are from June 1, when 160,234 people, or about 16 per cent of the population, were on it.

“It’s going to take time to make 160,000 calls,” Oldfield said. “We are not talking weeks, we are talking months.”

The interim CEO and president of Nova Scotia Health said people on the list are being asked where they live, whether they still need a family doctor, and to give an update on their health.

A spokesperson with the province’s Health Department says the government and its health authority are “working hard” to turn the wait-list registry into a useful tool, adding that the data will be shared once it is validated.

Nova Scotia’s NDP are calling on Premier Tim Houston to immediately release statistics on how many people are looking for a family doctor. On Tuesday, the NDP introduced a bill that would require the health minister to make the number public every month.

“It is unacceptable for the list to be more than three months out of date,” NDP Leader Claudia Chender said Tuesday.

Chender said releasing this data regularly is vital so Nova Scotians can track the government’s progress on its main 2021 campaign promise: fixing health care.

The number of people in need of a family doctor has more than doubled between the 2021 summer election campaign and June 2024. Since September 2021 about 300 doctors have been added to the provincial health system, the Health Department said.

“We’ll know if Tim Houston is keeping his 2021 election promise to fix health care when Nova Scotians are attached to primary care,” Chender said.

This report by The Canadian Press was first published Sept. 11, 2024.

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Newfoundland and Labrador monitoring rise in whooping cough cases: medical officer

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ST. JOHN’S, N.L. – Newfoundland and Labrador‘s chief medical officer is monitoring the rise of whooping cough infections across the province as cases of the highly contagious disease continue to grow across Canada.

Dr. Janice Fitzgerald says that so far this year, the province has recorded 230 confirmed cases of the vaccine-preventable respiratory tract infection, also known as pertussis.

Late last month, Quebec reported more than 11,000 cases during the same time period, while Ontario counted 470 cases, well above the five-year average of 98. In Quebec, the majority of patients are between the ages of 10 and 14.

Meanwhile, New Brunswick has declared a whooping cough outbreak across the province. A total of 141 cases were reported by last month, exceeding the five-year average of 34.

The disease can lead to severe complications among vulnerable populations including infants, who are at the highest risk of suffering from complications like pneumonia and seizures. Symptoms may start with a runny nose, mild fever and cough, then progress to severe coughing accompanied by a distinctive “whooping” sound during inhalation.

“The public, especially pregnant people and those in close contact with infants, are encouraged to be aware of symptoms related to pertussis and to ensure vaccinations are up to date,” Newfoundland and Labrador’s Health Department said in a statement.

Whooping cough can be treated with antibiotics, but vaccination is the most effective way to control the spread of the disease. As a result, the province has expanded immunization efforts this school year. While booster doses are already offered in Grade 9, the vaccine is now being offered to Grade 8 students as well.

Public health officials say whooping cough is a cyclical disease that increases every two to five or six years.

Meanwhile, New Brunswick’s acting chief medical officer of health expects the current case count to get worse before tapering off.

A rise in whooping cough cases has also been reported in the United States and elsewhere. The Pan American Health Organization issued an alert in July encouraging countries to ramp up their surveillance and vaccination coverage.

This report by The Canadian Press was first published Sept. 10, 2024.

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