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Is a single COVID-19 vaccine dose enough for those previously infected? – Global News

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As coronavirus vaccines continue to roll out to vulnerable populations across Canada, health officials are looking at data about the effectiveness of a single dose in preventing COVID-19 illness.

A new letter by two Canadian experts published in the New England Journal of Medicine (NEJM) last week stated that with a 92.6 per cent efficacy, the first dose of the Pfizer vaccine was “highly protective.”

Read more:
Delaying second dose of coronavirus vaccines is ‘risky gamble,’ experts say

During a news conference on Feb. 18, Dr. Howard Njoo, Canada’s deputy chief public health officer, said that according to early data, the indicators are that there is a “good level of protection” after just one dose.






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How COVID-19 vaccination plans are evolving in Quebec, Ontario


How COVID-19 vaccination plans are evolving in Quebec, Ontario

France’s health authority, H.A.S., has gone one step further in recommending that everyone who has been previously infected with COVID-19 receive a single shot, instead of the two-dose regimen prescribed by vaccine makers Pfizer and Moderna.

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The recommendation made on Feb. 12 says the single booster shot should be given three to six months after COVID-19 infection.

The reasoning, according to H.A.S., is that people who have had a confirmed infection should be considered protected for at least three months by post-infection immunity, whether the disease was symptomatic or not.

“It is an interesting approach to take,” said Rowland Kao, professor of veterinary epidemiology and data science at the University of Edinburgh in Scotland.

“And you would expect that natural immunity will give you .. a more broad response (than the first dose) because it is the original virus that is causing it.”






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Pfizer-BioNTech COVID-19 vaccine 80-90% effective after 1st dose


Pfizer-BioNTech COVID-19 vaccine 80-90% effective after 1st dose

A spokesperson for H.A.S. told Global News that the French health minister has yet to make a decision on the recommendation. For now, France is giving two shots for both the Pfizer and Moderna vaccine.

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Amid shortages in vaccine supplies and a rush to control the pandemic, some experts say this strategy is worth considering as it could potentially save precious doses.

Read more:
Johnson & Johnson one-shot vaccine is safe, prevents COVID-19, U.S. FDA says

Dr. Gerald Evans, chair of infectious diseases at Queen’s University in Kingston, Ont., said a single dose of vaccine in someone previously infected is “reasonable while we continue to have a short supply of vaccine globally.”

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Two small studies in the United States by Mount Sinai and the University of Maryland showed a single dose in people who had COVID-19 provided at least the same amount of protection as two shots in people who haven’t been infected. The data has not yet been peer-reviewed.

You could treat getting COVID-19 as like getting your first dose of vaccine,” said Dr. Zain Chagla, an infectious diseases physician at St. Joseph’s Healthcare in Hamilton.

A single dose could serve as a booster to get the “prime long-term response,” he told Global News.

“You could definitely save on vaccine supply with these mRNA vaccines by only giving those individuals a single dose moving forward.”

Some Canadian provinces have decided to delay giving the second dose, which some experts have called a “risky approach” and “a gamble.”

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Last week, New Brunswick health officials said the province will delay the second dose of the Pfizer-BioNTech vaccine for those who are considered to be at a lower risk.

In mid-January, Quebec announced that it was pushing the time between the two doses to a maximum of three months in an attempt to vaccinate more seniors faster with a first injection.

Vaccine manufacturers Pfizer and Moderna propose intervals of 21 and 28 days, respectively.






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Why is Health Canada taking so long to approve the AstraZeneca vaccine?


Why is Health Canada taking so long to approve the AstraZeneca vaccine?

In its recommendation for the previously infected, France’s H.A.S. says people who have proven immunosuppression, which makes them more vulnerable to severe COVID-19 illness, should be given the two doses.

It also says people who catch the virus in the days after a first dose is given should not receive a second shot within the usual timeframe, but within three to six months after infection.

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Read more:
Booster shots, new clinical trials — What the COVID-19 variants could mean for vaccines

According to the data from the clinical trials, Pfizer’s vaccine, which is 95 per cent effective, can offer partial protection as early as 12 days after the first dose.

Kao said the immediate protection after the first dose and second dose is quite similar.

However, it still remains to be seen what the long-term immune response will be after the first dose.

We really don’t know how long that protection is going to last,“ said Kao.

The second dose is really there to give you that long-lasting immunity.”






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Quebec public health experts support delaying second COVID-19 dose


Quebec public health experts support delaying second COVID-19 dose

Data analysis by Canadian experts published in the NEJM found a 68.5 per cent vaccine efficacy beginning seven days after Pfizer’s first dose and a 92.6 percent efficacy two weeks after a single shot.

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Based on the evidence so far, Chagla says it is premature to roll out the single-dose strategy on a wide scale and that more research was needed on that front.

“If you could prove that works, you really do save a significant amount of vaccine … and you really can change your vaccine strategy almost overnight if you can implement something like that.”

— With files from Global News’ Linda Boyle

© 2021 Global News, a division of Corus Entertainment Inc.

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Telus prioritizing ‘most important customers,’ avoiding ‘unprofitable’ offers: CFO

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Telus Corp. says it is avoiding offering “unprofitable” discounts as fierce competition in the Canadian telecommunications sector shows no sign of slowing down.

The company said Friday it had fewer net new customers during its third quarter compared with the same time last year, as it copes with increasingly “aggressive marketing and promotional pricing” that is prompting more customers to switch providers.

Telus said it added 347,000 net new customers, down around 14.5 per cent compared with last year. The figure includes 130,000 mobile phone subscribers and 34,000 internet customers, down 30,000 and 3,000, respectively, year-over-year.

The company reported its mobile phone churn rate — a metric measuring subscribers who cancelled their services — was 1.09 per cent in the third quarter, up from 1.03 per cent in the third quarter of 2023. That included a postpaid mobile phone churn rate of 0.90 per cent in its latest quarter.

Telus said its focus is on customer retention through its “industry-leading service and network quality, along with successful promotions and bundled offerings.”

“The customers we have are the most important customers we can get,” said chief financial officer Doug French in an interview.

“We’ve, again, just continued to focus on what matters most to our customers, from a product and customer service perspective, while not loading unprofitable customers.”

Meanwhile, Telus reported its net income attributable to common shares more than doubled during its third quarter.

The telecommunications company said it earned $280 million, up 105.9 per cent from the same three-month period in 2023. Earnings per diluted share for the quarter ended Sept. 30 was 19 cents compared with nine cents a year earlier.

It reported adjusted net income was $413 million, up 10.7 per cent year-over-year from $373 million in the same quarter last year. Operating revenue and other income for the quarter was $5.1 billion, up 1.8 per cent from the previous year.

Mobile phone average revenue per user was $58.85 in the third quarter, a decrease of $2.09 or 3.4 per cent from a year ago. Telus said the drop was attributable to customers signing up for base rate plans with lower prices, along with a decline in overage and roaming revenues.

It said customers are increasingly adopting unlimited data and Canada-U.S. plans which provide higher and more stable ARPU on a monthly basis.

“In a tough operating environment and relative to peers, we view Q3 results that were in line to slightly better than forecast as the best of the bunch,” said RBC analyst Drew McReynolds in a note.

Scotiabank analyst Maher Yaghi added that “the telecom industry in Canada remains very challenging for all players, however, Telus has been able to face these pressures” and still deliver growth.

The Big 3 telecom providers — which also include Rogers Communications Inc. and BCE Inc. — have frequently stressed that the market has grown more competitive in recent years, especially after the closing of Quebecor Inc.’s purchase of Freedom Mobile in April 2023.

Hailed as a fourth national carrier, Quebecor has invested in enhancements to Freedom’s network while offering more affordable plans as part of a set of commitments it was mandated by Ottawa to agree to.

The cost of telephone services in September was down eight per cent compared with a year earlier, according to Statistics Canada’s most recent inflation report last month.

“I think competition has been and continues to be, I’d say, quite intense in Canada, and we’ve obviously had to just manage our business the way we see fit,” said French.

Asked how long that environment could last, he said that’s out of Telus’ hands.

“What I can control, though, is how we go to market and how we lead with our products,” he said.

“I think the conditions within the market will have to adjust accordingly over time. We’ve continued to focus on digitization, continued to bring our cost structure down to compete, irrespective of the price and the current market conditions.”

Still, Canada’s telecom regulator continues to warn providers about customers facing more charges on their cellphone and internet bills.

On Tuesday, CRTC vice-president of consumer, analytics and strategy Scott Hutton called on providers to ensure they clearly inform their customers of charges such as early cancellation fees.

That followed statements from the regulator in recent weeks cautioning against rising international roaming fees and “surprise” price increases being found on their bills.

Hutton said the CRTC plans to launch public consultations in the coming weeks that will focus “on ensuring that information is clear and consistent, making it easier to compare offers and switch services or providers.”

“The CRTC is concerned with recent trends, which suggest that Canadians may not be benefiting from the full protections of our codes,” he said.

“We will continue to monitor developments and will take further action if our codes are not being followed.”

French said any initiative to boost transparency is a step in the right direction.

“I can’t say we are perfect across the board, but what I can say is we are absolutely taking it under consideration and trying to be the best at communicating with our customers,” he said.

“I think everyone looking in the mirror would say there’s room for improvement.”

This report by The Canadian Press was first published Nov. 8, 2024.

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TC Energy cuts cost estimate for Southeast Gateway pipeline project in Mexico

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CALGARY – TC Energy Corp. has lowered the estimated cost of its Southeast Gateway pipeline project in Mexico.

It says it now expects the project to cost between US$3.9 billion and US$4.1 billion compared with its original estimate of US$4.5 billion.

The change came as the company reported a third-quarter profit attributable to common shareholders of C$1.46 billion or $1.40 per share compared with a loss of C$197 million or 19 cents per share in the same quarter last year.

Revenue for the quarter ended Sept. 30 totalled C$4.08 billion, up from C$3.94 billion in the third quarter of 2023.

TC Energy says its comparable earnings for its latest quarter amounted to C$1.03 per share compared with C$1.00 per share a year earlier.

The average analyst estimate had been for a profit of 95 cents per share, according to LSEG Data & Analytics.

This report by The Canadian Press was first published Nov. 7, 2024.

Companies in this story: (TSX:TRP)

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BCE reports Q3 loss on asset impairment charge, cuts revenue guidance

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BCE Inc. reported a loss in its latest quarter as it recorded $2.11 billion in asset impairment charges, mainly related to Bell Media’s TV and radio properties.

The company says its net loss attributable to common shareholders amounted to $1.24 billion or $1.36 per share for the quarter ended Sept. 30 compared with a profit of $640 million or 70 cents per share a year earlier.

On an adjusted basis, BCE says it earned 75 cents per share in its latest quarter compared with an adjusted profit of 81 cents per share in the same quarter last year.

“Bell’s results for the third quarter demonstrate that we are disciplined in our pursuit of profitable growth in an intensely competitive environment,” BCE chief executive Mirko Bibic said in a statement.

“Our focus this quarter, and throughout 2024, has been to attract higher-margin subscribers and reduce costs to help offset short-term revenue impacts from sustained competitive pricing pressures, slow economic growth and a media advertising market that is in transition.”

Operating revenue for the quarter totalled $5.97 billion, down from $6.08 billion in its third quarter of 2023.

BCE also said it now expects its revenue for 2024 to fall about 1.5 per cent compared with earlier guidance for an increase of zero to four per cent.

The company says the change comes as it faces lower-than-anticipated wireless product revenue and sustained pressure on wireless prices.

BCE added 33,111 net postpaid mobile phone subscribers, down 76.8 per cent from the same period last year, which was the company’s second-best performance on the metric since 2010.

It says the drop was driven by higher customer churn — a measure of subscribers who cancelled their service — amid greater competitive activity and promotional offer intensity. BCE’s monthly churn rate for the category was 1.28 per cent, up from 1.1 per cent during its previous third quarter.

The company also saw 11.6 per cent fewer gross subscriber activations “due to more targeted promotional offers and mobile device discounting compared to last year.”

Bell’s wireless mobile phone average revenue per user was $58.26, down 3.4 per cent from $60.28 in the third quarter of the prior year.

This report by The Canadian Press was first published Nov. 7, 2024.

Companies in this story: (TSX:BCE)

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