Island Health says one case of monkeypox in a person who lives on the south Island has been confirmed through laboratory testing.
Public health teams are conducting follow-up on the case, including managing contacts identified through contact tracing.
In a statement, Island Health says the public health team received confirmation of the case on Thursday, but sent out the notice to the public on Friday.
Island Health says the risk to the public is very low, and the virus is spread through person-to-person contact.
Vaccinations are being provided to high-risk contacts identified through contact tracing in Island Health.
Symptoms can take anywhere between five to 21 days to appear, but typically appear within the first two weeks following exposure.
There are two stages to the disease. The first being flu-like symptoms, followed by a rash usually with sores and blisters.
People are considered infectious from when the symptoms first appear, until the sores crust over, are dry, and new skin is visible.
” Most people with monkeypox have mild symptoms and do not require any specific interventions,” Island Health says in a statement. “Treatment for monkeypox remains supportive and targeted on symptoms (e.g. fever control, hydration support, treat secondary infections).”
Have we been treating depression the wrong way for decades? – CBC News
This is an excerpt from Second Opinion, a weekly analysis of health and medical science news. If you haven’t subscribed yet, you can do that by clicking here.
A new analysis of the cause of depression has seemingly upended what we know about this common condition and challenged the use of antidepressants. But it may also leave patients with more questions than answers as the science evolves.
A systematic umbrella review of 17 studies published in Molecular Psychology on July 20 looked at the decades-old theory that depression is caused by low serotonin, and found there was “no consistent evidence” of “an association between serotonin and depression.”
The theory that depression is caused by a chemical imbalance in the brain has been around since the 1960s. But for years, many experts have doubted this, feeling it oversimplified a complex condition.
“The serotonin theory is very old and has been very popular since the ’90s, when the pharmaceutical industry started promoting it,” said Dr. Joanna Moncrieff, a psychiatry professor at University College London and lead author of the study.
“But since about 2005, probably a bit before then, there’s been sort of rumours that actually the evidence isn’t very strong, or it’s inconsistent. Some studies are positive, some studies are negative, but no one’s really got that evidence together anywhere.”
Moncrieff and her team set out to challenge the serotonin theory in a systematic review of available research. They also went a step further in their conclusion by suggesting that antidepressants are ineffective at treating depression — and have largely worked as a placebo.
“Evidence from placebo-controlled trials show that antidepressants are a little bit better than a sugar tablet,” she said. “And if that little difference is not to do with rectifying a chemical imbalance, improving low serotonin levels, what is it to do with?”
The research paints a compelling picture that depression isn’t caused by low serotonin alone. Many experts say this is already widely accepted and that it’s also true that antidepressants can be extremely beneficial to some patients — even if we don’t know exactly why.
So where does this leave patients and physicians, and could the analysis impact the way we treat depression in the future?
Are antidepressants effective against depression?
Antidepressants are widely believed to affect the behaviour of neurotransmitters, chemical messengers in the brain like serotonin and dopamine, in a way that can alter emotions and mood to help improve the symptoms of depression in some patients.
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People with depression can face a wide range of symptoms, including persistent feelings of sadness and desperation, changes in appetite, sleep deprivation, fatigue, irritability and loss of interest in hobbies and social connections that can impact everyday life.
While it’s unclear exactly how antidepressants work at a biological level to alleviate those symptoms, it’s clear that they can still be hugely helpful to some patients.
“It’s a typical discovery in medicine — you find a drug that works, but you don’t quite know why,” said Dr. Phil Cowen, a professor of psychopharmacology at the University of Oxford.
“[The review] is a debunking exercise and in a way, they’re criticizing older studies that were hard to do,” he said. “These [older] studies, clearly, were very indirect and they’re messy, and I don’t think anyone thought that they were that great.”
Moncrieff’s team found that some depressed patients actually had higher serotonin levels in certain areas of the brain, and in some cases the long-term use of antidepressants could actually lower the amount of serotonin — though the findings were “inconsistent.”
“I think it makes a huge difference, because how [antidepressants] work actually influences whether they work,” she said. “It influences how helpful we think they are.”
The findings have caused a major stir in the media and scientific community, with hundreds of news outlets covering the study — quickly landing it in the top five per cent of all research scored by Altmetric, a company that analyzes where published research is shared.
Findings of this perceived magnitude can have a seismic impact on the way we understand and treat a widespread condition like depression, which affects an estimated one in eight Canadians at some point in their lives.
While the research questions the very nature of what we know about depression, many doctors are hesitant to change the way we treat it.
Antidepressants can be ‘lifesaver’ for some
Dr. David Juurlink, head of clinical pharmacology at Sunnybrook Health Sciences Centre in Toronto, said he’s not surprised by the findings, because the chemical imbalance theory for depression is now widely seen as an “obvious oversimplification” for a complex condition.
“Although I think doctors prescribe serotonin-enhancing antidepressants far too often, in part because of this oversimplification, it’s important to acknowledge that they really do improve the well-being of some patients,” he said in an email.
“How exactly they do that isn’t as clear-cut as we’ve been led to believe.”
Dr. David Gratzer, a psychiatrist and attending physician at the Centre for Addiction and Mental Health (CAMH) in Toronto, said he wasn’t surprised by the findings — just that they got as much attention as they did.
“This suggestion that depression is all about serotonin all the time hasn’t been accepted by psychiatrists for many years, probably many decades,” he said, adding that the researchers are “terribly biased” in their assessment of antidepressants.
“Their paper shows things are much more complicated than serotonin — no surprise — and then they turn around and say, ‘You see, that’s another example of the fact that antidepressants don’t really work.’ One doesn’t necessarily give rise to the other.”
Gratzer said he still prescribes antidepressants regularly as a treatment option for depression, and has no plans to stop doing so based on the research.
“That’s not going to change. These medications work,” he said.
“An antidepressant is not necessarily [recommended] in everyone who has depression — some people might in fact do better with talking therapy — but it is certainly a tool in our tool kit and, to be blunt, it’s a lifesaver for some of our patients.”
Research calls antidepressants into question
Moncrieff said the research found that another way in which antidepressants may function is by desensitizing the brain to negative emotions associated with depression. In theory, that could also impact other feelings.
She said one of the effects previous studies have reported in patients is “emotional numbing,” where they not only don’t have unwanted emotions like depression and anxiety, but positive emotions like joy and happiness.
“There may be some people that feel that that’s an effect they want. But I think generally, people aren’t going to want to be emotionally numbed, not for long periods, anyway, and so I think it totally changes the sorts of decisions people might make about antidepressants,” said Moncrieff.
Chris Davey, the head of the department of psychiatry at the University of Melbourne, said in an email that undermining the confidence that people with depression have in their treatments can be “very damaging.”
“People will stop their medications suddenly, without supervision,” he said, “which can cause dramatic deteriorations in their mental health.”
Davey said he is concerned that the paper diminished a treatment option that can be incredibly beneficial to some patients, especially when alternatives may not always be available to those at risk of severe depression.
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“This [research] shouldn’t make any difference to the treatment of depression. I hope it makes people realize that depression is a very complex condition, and that there are no simple explanations for it,” Davey said.
“Everyone should know that improving their diet, exercising more and paying attention to their sleep can be helpful. Everyone should have access to psychotherapy. And for those people for whom those things don’t help, that’s when we think about medications.”
Gratzer said there are many new areas of research into treatment options for depression that can be beneficial, including novel ways of delivering psychotherapy, emerging medications and discoveries like the use of ketamine.
Ketamine is a general anesthetic first approved in Canada in the 1960s for medical or veterinary surgery, as well as a psychedelic party drug sold on the illicit market. It’s also increasingly being used as a fast-acting and effective treatment for depression in low doses, by working to restore synapses in the brain that are destroyed by stress.
There’s “an understanding that certain life experiences might be more connected, and so research is very active. Maybe at the end of the day, we’ll understand depression isn’t one illness,” Gratzer said.
“As is often the case with mental health care, these are early days.”
Polio virus found in New York City wastewater, suggesting local transmission – CBC News
Health officials identified the virus that causes polio in New York City’s wastewater, suggesting local transmission of the virus, state authorities said on Friday, urging unvaccinated New Yorkers to get vaccinated.
“The NYC Heath Department and the New York State Department of Health have identified poliovirus in sewage in NYC,
suggesting local transmission of the virus,” the city’s health department said in a statement on Friday.
“Polio can lead to paralysis and even death. We urge unvaccinated New Yorkers to get vaccinated now.”
The identification comes weeks after a case of polio in an adult was made public on July 21 in Rockland County, marking the nation’s first confirmed case in nearly 10 years.
Earlier this month, health officials said the virus was found in wastewater in the New York City suburb a month before health officials there announced the Rockland County case.
The U.S. Centers for Disease Control and Prevention (CDC) said at the time that it was not clear whether the virus was actively spreading in New York or elsewhere in the United States.
Evidence of virus in London
There is no cure for polio, which can cause irreversible paralysis in some cases, but it can be prevented by a vaccine made available in 1955.
New York officials have said they are opening vaccine clinics to help unvaccinated residents get their shots.
Inactivated polio vaccine (IPV) is the only polio vaccine that has been given in the United States since 2000, according to the CDC. It is given by shot in the leg or arm, depending on the patient’s age.
On Wednesday, British health authorities announced they will offer a polio booster dose to children aged one to nine in London, after finding evidence the virus has been spreading in multiple regions of the capital. Britain’s Health Security Agency said polio virus samples were found in sewage water from eight boroughs of London, but there were no confirmed infections.
Polio is often asymptomatic and people can transmit the virus even when they do not appear sick. But it can produce
mild, flu-like symptoms that can take as long as 30 days to appear, officials said.
It can strike at any age but the majority of those affected are children aged three and younger.
Monkeypox: gov’t has no plans to call public health emergency – CTV News
Canada’s chief public health officer Dr. Theresa Tam says there are no plans at the moment to declare monkeypox a public health emergency.
While the World Health Organization and the United States have both recently done so, Tam said there is little benefit to declaring a federal public health emergency in Canada, because of the structure of regional and provincial public health authorities.
She said a federal emergency declaration would involve the Emergencies Act — which hasn’t even been invoked to address the nearly two-and-a-half-year COVID-19 pandemic in Canada. Tam said thus far, Canada has already been able to mobilize vaccines, therapeutics, and funding to tackle monkeypox.
Tam also said local and provincial authorities have more flexibility, and have been able to respond to the rise in monkeypox cases. Local and provincial authorities could also decide to declare the virus a public health emergency at those levels, as many did with COVID-19.
“To date our discussions have focused on testing, working with community organizations to raise awareness on ways to limit spread the virus, and deployment of the Imvamune vaccine and therapeutics,” Tam said. “As the global monkeypox outbreak continues to be a serious concern, focusing efforts on the impacted communities in Canada and worldwide, including with vaccinations, we have an opportunity to contain the spread.”
To day, approximately 99,000 doses of Imvamune have been deployed to the provinces and territories, and more than 50,000 people have been vaccinated, Tam said.
Canada’s Deputy Chief Public Health Officer Dr. Howard Njoo said the approach continues to be vaccinating higher risk communities first, and there are currently enough doses to do so.
Tam says there have been approximately 31,000 cases of monkeypox reported globally, with 1,059 in Canada, mostly in Ontario.
While cases of the virus first started popping up in Quebec, Ontario has since surpassed it in its number of infections.
To date, there have been 28 hospitalizations — two in intensive care — from monkeypox in Canada, and no deaths. Tam said it’s too soon to tell whether the number of cases has plateaued in Canada.
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