Lifestyle changes may combat a dementia that strikes people in their 40s and 50s - CNN | Canada News Media
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Lifestyle changes may combat a dementia that strikes people in their 40s and 50s – CNN

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The first symptom is likely a loss of interest in life and the well-being of others. A person might ignore their spouse or children’s feelings, get uncharacteristically frustrated and say or do inappropriate things — such as laugh at a funeral.
Even worse, they’ll likely have no idea they have changed.
“It’s a pretty devastating disease that impacts people in the prime of their lives,” said neurologist Kaitlin Casaletto, an assistant professor in the Memory and Aging Center at the University of California, San Francisco. “It’s especially hard on family members who can see the changes in their loved one they themselves often can’t see.”
Science has struggled to provide interventions to help these patients. Now, a new study published Wednesday suggests that lifestyle changes may help slow the disease progression.
Casaletto and her colleagues followed the activity levels of 105 people with the inherited form of the disease, the first study to do so in this population. They found people who ranked highest in levels of mental and physical activity slowed their functional decline from the disease by half.
“This is an extremely important study providing the strongest evidence yet that lifestyle factors can positively impact brain health, not only for Alzheimer’s disease, but frontotemporal lobar dementia as well,” said neurologist Dr. Richard Isaacson, director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine.
“The study is even more impactful in that patients had a gene that would definitely cause dementia, but they were still able to impact cognitive decline by over 55%,” Isaacson said.
“It was a remarkable effect to see so early on,” Casaletto said. “If this were a drug, we would be giving it to all of our patients.”

A devastating disease

An estimated 50,000 to 60,000 Americans live with FTD or frontotemporal dementia, Casaletto said. About 30% of all cases are inherited. In comparison, only about 1% of Alzheimer’s cases are passed on via a familial gene, she said.
In the most common form of FTD, called “behavioral variant,” the executive (frontal) and emotive (temporal) parts of the brain are affected, thus impacting a person’s ability to control their thinking and emotions.
“The connection between the two is critically important,” Casaletto said. “So if you think of the frontal lobe as the start-stop inhibition control center, with the temporal lobe in charge of empathy and anger, you can imagine that when those start to degenerate how wildly unregulated one can become.”
In two other variants, the disease attacks areas of the frontal lobe responsible for names of objects and pronouncing words, leading to difficulty with reading, writing and speaking.
As the diseases progress, people have trouble concentrating, planning, making decisions and understanding conversations. They begin overeating, or forget to bathe. They may become compulsive buyers, steal from neighbors or rummage in their garbage, even shoplift at stores. Sometimes, they might begin to walk more slowly, show less muscle strength and have trouble swallowing.
There is no cure, and little science can do. Antidepressants called selective serotonin reuptake inhibitors may help with irritability, agitation and apathy. Life span after diagnosis is only six to 10 years.

The role of mental and physical activity

Ongoing research in Alzheimer’s suggests lifestyle factors such as adequate sleep, a healthy diet, and physical and mental exercises can improve brain health. In fact, a recent study on Alzheimer’s found personalized lifestyle interventions not only stopped cognitive decline in people at risk for Alzheimer’s, but actually increased their memory and thinking skills within 18 months.
But no one had ever studied those interventions in frontotemporal dementia.
“There’s incredible variability in FTD, even among people with the same genetic mutations driving their disease. Some people are just more resilient than others for reasons we still don’t understand,” Casaletto said. The study was designed to explore the role of lifestyle in those differences.
People with FTD in the study were mostly asymptomatic or had only mild, early-stage symptoms. Caregivers were asked to rate their loved one’s cognitive and physical activity over several years. The type of physical activity wasn’t critical — it could be walking, jogging, even doing heavy housework or yard chores.
“Studies show even walking is associated with better cognitive outcomes,” Casaletto said. “It seems that every movement counts.”
A cognitively active lifestyle was defined as reading, writing, going to a concert, socializing, doing games, puzzles and hobbies, she said, anything that challenges the brain.
MRIs recorded disease levels in the brain at the start of the study; participants were given tests of thinking and memory and then rechecked annually. The results at the end of two years were surprising: Despite continued degeneration of brain tissue on scans, the people who scored in the top 25% of either mental or physical activity performed twice as well on cognitive tests as those in the lowest 5% of activity.
“Our results suggest that even people with a genetic predisposition for FTD can still take actions to increase their chances of living a long and productive life,” Casaletto said. “Their fate may not be set in stone.”
The study will continue and researchers plan to outfit participants with activity trackers to better understand which type of physical activity may be most beneficial. They also plan to tease out other factors that might be involved; at this time, the results are only a correlation.
Despite this study’s limitations, this small but growing pool of research should be a wake-up call to anyone facing a diagnosis of dementia, Isaacson said.
“It is essential for people at risk for dementia and their physicians to change their thinking from, ‘There is nothing we can do,'” Isaacson said. “People at risk should feel empowered and hopeful that they can take some degree of control of their brain health.”

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What’s the greatest holiday gift: lips, hair, skin? Give the gift of great skin this holiday season

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Give the gift of great skin this holiday season

Skinstitut Holiday Gift Kits take the stress out of gifting

Toronto, October 31, 2024 – Beauty gifts are at the top of holiday wish lists this year, and Laser Clinics Canada, a leader in advanced beauty treatments and skincare, is taking the pressure out of seasonal shopping. Today, Laser Clincs Canada announces the arrival of its 2024 Holiday Gift Kits, courtesy of Skinstitut, the exclusive skincare line of Laser Clinics Group.

In time for the busy shopping season, the limited-edition Holiday Gifts Kits are available in Laser Clinics locations in the GTA and Ottawa. Clinics are conveniently located in popular shopping centers, including Hillcrest Mall, Square One, CF Sherway Gardens, Scarborough Town Centre, Rideau Centre, Union Station and CF Markville. These limited-edition Kits are available on a first come, first served basis.

“These kits combine our best-selling products, bundled to address the most relevant skin concerns we’re seeing among our clients,” says Christina Ho, Senior Brand & LAM Manager at Laser Clinics Canada. “With several price points available, the kits offer excellent value and suit a variety of gift-giving needs, from those new to cosmeceuticals to those looking to level up their skincare routine. What’s more, these kits are priced with a savings of up to 33 per cent so gift givers can save during the holiday season.

There are two kits to select from, each designed to address key skin concerns and each with a unique theme — Brightening Basics and Hydration Heroes.

Brightening Basics is a mix of everyday essentials for glowing skin for all skin types. The bundle comes in a sleek pink, reusable case and includes three full-sized products: 200ml gentle cleanser, 50ml Moisture Defence (normal skin) and 30ml1% Hyaluronic Complex Serum. The Brightening Basics kit is available at $129, a saving of 33 per cent.

Hydration Heroes is a mix of hydration essentials and active heroes that cater to a wide variety of clients. A perfect stocking stuffer, this bundle includes four deluxe products: Moisture 15 15 ml Defence for normal skin, 10 ml 1% Hyaluronic Complex Serum, 10 ml Retinol Serum and 50 ml Expert Squalane Cleansing Oil. The kit retails at $59.

In addition to the 2024 Holiday Gifts Kits, gift givers can easily add a Laser Clinic Canada gift card to the mix. Offering flexibility, recipients can choose from a wide range of treatments offered by Laser Clinics Canada, or they can expand their collection of exclusive Skinstitut products.

 

Brightening Basics 2024 Holiday Gift Kit by Skinstitut, available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

Hydration Heroes 2024 Holiday Gift Kit by Skinstitut – available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

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Here is how to prepare your online accounts for when you die

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LONDON (AP) — Most people have accumulated a pile of data — selfies, emails, videos and more — on their social media and digital accounts over their lifetimes. What happens to it when we die?

It’s wise to draft a will spelling out who inherits your physical assets after you’re gone, but don’t forget to take care of your digital estate too. Friends and family might treasure files and posts you’ve left behind, but they could get lost in digital purgatory after you pass away unless you take some simple steps.

Here’s how you can prepare your digital life for your survivors:

Apple

The iPhone maker lets you nominate a “ legacy contact ” who can access your Apple account’s data after you die. The company says it’s a secure way to give trusted people access to photos, files and messages. To set it up you’ll need an Apple device with a fairly recent operating system — iPhones and iPads need iOS or iPadOS 15.2 and MacBooks needs macOS Monterey 12.1.

For iPhones, go to settings, tap Sign-in & Security and then Legacy Contact. You can name one or more people, and they don’t need an Apple ID or device.

You’ll have to share an access key with your contact. It can be a digital version sent electronically, or you can print a copy or save it as a screenshot or PDF.

Take note that there are some types of files you won’t be able to pass on — including digital rights-protected music, movies and passwords stored in Apple’s password manager. Legacy contacts can only access a deceased user’s account for three years before Apple deletes the account.

Google

Google takes a different approach with its Inactive Account Manager, which allows you to share your data with someone if it notices that you’ve stopped using your account.

When setting it up, you need to decide how long Google should wait — from three to 18 months — before considering your account inactive. Once that time is up, Google can notify up to 10 people.

You can write a message informing them you’ve stopped using the account, and, optionally, include a link to download your data. You can choose what types of data they can access — including emails, photos, calendar entries and YouTube videos.

There’s also an option to automatically delete your account after three months of inactivity, so your contacts will have to download any data before that deadline.

Facebook and Instagram

Some social media platforms can preserve accounts for people who have died so that friends and family can honor their memories.

When users of Facebook or Instagram die, parent company Meta says it can memorialize the account if it gets a “valid request” from a friend or family member. Requests can be submitted through an online form.

The social media company strongly recommends Facebook users add a legacy contact to look after their memorial accounts. Legacy contacts can do things like respond to new friend requests and update pinned posts, but they can’t read private messages or remove or alter previous posts. You can only choose one person, who also has to have a Facebook account.

You can also ask Facebook or Instagram to delete a deceased user’s account if you’re a close family member or an executor. You’ll need to send in documents like a death certificate.

TikTok

The video-sharing platform says that if a user has died, people can submit a request to memorialize the account through the settings menu. Go to the Report a Problem section, then Account and profile, then Manage account, where you can report a deceased user.

Once an account has been memorialized, it will be labeled “Remembering.” No one will be able to log into the account, which prevents anyone from editing the profile or using the account to post new content or send messages.

X

It’s not possible to nominate a legacy contact on Elon Musk’s social media site. But family members or an authorized person can submit a request to deactivate a deceased user’s account.

Passwords

Besides the major online services, you’ll probably have dozens if not hundreds of other digital accounts that your survivors might need to access. You could just write all your login credentials down in a notebook and put it somewhere safe. But making a physical copy presents its own vulnerabilities. What if you lose track of it? What if someone finds it?

Instead, consider a password manager that has an emergency access feature. Password managers are digital vaults that you can use to store all your credentials. Some, like Keeper,Bitwarden and NordPass, allow users to nominate one or more trusted contacts who can access their keys in case of an emergency such as a death.

But there are a few catches: Those contacts also need to use the same password manager and you might have to pay for the service.

___

Is there a tech challenge you need help figuring out? Write to us at onetechtip@ap.org with your questions.

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Pediatric group says doctors should regularly screen kids for reading difficulties

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The Canadian Paediatric Society says doctors should regularly screen children for reading difficulties and dyslexia, calling low literacy a “serious public health concern” that can increase the risk of other problems including anxiety, low self-esteem and behavioural issues, with lifelong consequences.

New guidance issued Wednesday says family doctors, nurses, pediatricians and other medical professionals who care for school-aged kids are in a unique position to help struggling readers access educational and specialty supports, noting that identifying problems early couldhelp kids sooner — when it’s more effective — as well as reveal other possible learning or developmental issues.

The 10 recommendations include regular screening for kids aged four to seven, especially if they belong to groups at higher risk of low literacy, including newcomers to Canada, racialized Canadians and Indigenous Peoples. The society says this can be done in a two-to-three-minute office-based assessment.

Other tips encourage doctors to look for conditions often seen among poor readers such as attention-deficit hyperactivity disorder; to advocate for early literacy training for pediatric and family medicine residents; to liaise with schools on behalf of families seeking help; and to push provincial and territorial education ministries to integrate evidence-based phonics instruction into curriculums, starting in kindergarten.

Dr. Scott McLeod, one of the authors and chair of the society’s mental health and developmental disabilities committee, said a key goal is to catch kids who may be falling through the cracks and to better connect families to resources, including quicker targeted help from schools.

“Collaboration in this area is so key because we need to move away from the silos of: everything educational must exist within the educational portfolio,” McLeod said in an interview from Calgary, where he is a developmental pediatrician at Alberta Children’s Hospital.

“Reading, yes, it’s education, but it’s also health because we know that literacy impacts health. So I think that a statement like this opens the window to say: Yes, parents can come to their health-care provider to get advice, get recommendations, hopefully start a collaboration with school teachers.”

McLeod noted that pediatricians already look for signs of low literacy in young children by way of a commonly used tool known as the Rourke Baby Record, which offers a checklist of key topics, such as nutrition and developmental benchmarks, to cover in a well-child appointment.

But he said questions about reading could be “a standing item” in checkups and he hoped the society’s statement to medical professionals who care for children “enhances their confidence in being a strong advocate for the child” while spurring partnerships with others involved in a child’s life such as teachers and psychologists.

The guidance said pediatricians also play a key role in detecting and monitoring conditions that often coexist with difficulty reading such as attention-deficit hyperactivity disorder, but McLeod noted that getting such specific diagnoses typically involves a referral to a specialist, during which time a child continues to struggle.

He also acknowledged that some schools can be slow to act without a specific diagnosis from a specialist, and even then a child may end up on a wait list for school interventions.

“Evidence-based reading instruction shouldn’t have to wait for some of that access to specialized assessments to occur,” he said.

“My hope is that (by) having an existing statement or document written by the Canadian Paediatric Society … we’re able to skip a few steps or have some of the early interventions present,” he said.

McLeod added that obtaining specific assessments from medical specialists is “definitely beneficial and advantageous” to know where a child is at, “but having that sort of clear, thorough assessment shouldn’t be a barrier to intervention starting.”

McLeod said the society was partly spurred to act by 2022’s “Right to Read Inquiry Report” from the Ontario Human Rights Commission, which made 157 recommendations to address inequities related to reading instruction in that province.

He called the new guidelines “a big reminder” to pediatric providers, family doctors, school teachers and psychologists of the importance of literacy.

“Early identification of reading difficulty can truly change the trajectory of a child’s life.”

This report by The Canadian Press was first published Oct. 23, 2024.

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