NEW YORK: Three patients whose lower bodies were left completely paralysed after spinal cord injuries were able to walk, cycle and swim using a nerve-stimulation device controlled by a touchscreen tablet, researchers reported on Monday.
The patients’ injuries to a region called the thoracic spine – below the neck and above the lowest part of the back – were sustained one to nine years before receiving the treatment. They were able to take their first steps within an hour after neurosurgeons first implanted prototypes of a nerve-stimulation device remotely controlled by artificial-intelligence software.
Over the next six months, the patients regained the ability to engage in the more advanced activities – walking, cycling and swimming in community settings outside of the clinic – by controlling the nerve-stimulation devices themselves using a touchscreen tablet, the researchers said.
The patients – men ages 29, 32, and 41 – all were injured in motor bike accidents.
Grégoire Courtine and Jocelyne Bloch of the Swiss Federal Institute of Technology in Lausanne led the study published in the journal Nature Medicine. They helped establish a Netherlands-based technology company called Onward Medical that is working to commercialise the system.
The company expects to launch a trial in about a year involving 70 to 100 patients, primarily in the United States, Courtine said.
There is no existing treatment to enable the spinal cord to heal itself, but researchers have pursued ways to help paralysed people regain mobility through technology.
If this study’s early results are confirmed in larger studies, people immobilised by spinal cord injuries may someday be able to open a smartphone or talk to a smartwatch, select an activity such as “walk” or “sit”, then send a message to an implanted device that will stimulate their nerves and muscles to make the appropriate movements happen, the researchers said.
Normally to initiate movement the brain sends a message to the spinal cord, telling it to stimulate a pool of nerve cells that in turn activate the necessary muscles, Bloch said.
“It’s something we don’t even think about,” Bloch said. “It comes automatically.”
After complete spinal cord injury, messages from the brain cannot reach the nerves. Other researchers have tried to help paralysed patients walk by stimulating nerves through the back of the spine, using broad electrical fields emitted by implanted devices originally designed to control chronic pain, Courtine said.
Courtine and Bloch and their team redesigned the devices so that electrical signals would enter the spine from the sides instead of from the back. This approach allows very specific targeting and activation of spinal cord regions, Courtine said.
They then devised artificial intelligence algorithms that instruct electrodes on the device to emit signals to stimulate, in the proper sequence, the individual nerves that control the trunk and leg muscles needed for various activities such as getting up from a chair, sitting down and walking.
The software is tailored to each patient’s anatomy, Courtine said.
When the device was implanted, patients could “immediately activate their legs and step”, Bloch said.
But because their muscles were weak from disuse, they needed help with weight-bearing, and they needed to learn how to work with the technology, the researchers said.
The researchers noted that while the patients regained the ability to perform various activities, including controlling their truck muscles, for “extensive periods,” they did not regain natural movements.
Still, Bloch said, “The more they train, the more they start lifting their muscles, the more fluid it becomes.”
Another peer-reviewed paper by a separate research team in Israel published on Monday in the journal Advanced Science describes an experimental approach for repairing spinal cord injuries. Researchers at Tel Aviv University attempted to repair the spinal cords in injured mice using adult human cells that had been engineered to behave like embryonic stem cells, which can develop into any type of cell in the body.
The animals’ spinal cords had formed scar tissue, which has impeded any benefit of such cells in earlier studies. The researchers first allowed the stem cells to flourish in a special test tube environment, only transplanting them into the mice after the cells had matured into a small network of nerve cells and after the scar tissue had been surgically removed.
They reported achieving an 80 per cent success rate in restoring movement and sensation to the paralysed mice. The researchers said they aim to launch human trials within a few years.
Efforts to use such stem cells to help the spine repair itself and restore the function of organs and limbs have yet to produce an approved treatment in humans.
“There is a long way to prove that it works also in humans, but this is our goal,” said Tal Dvir, who led the team at the Sagol Center for Regenerative Biotechnology.
2022-06-29 | NDAQ:RKLB | Press Release | Rocket Lab USA Inc. – Stockhouse
Rocket Lab USA, Inc. (Nasdaq: RKLB) (“Rocket Lab” or “the Company”), a leading launch and space systems company, today announced its Lunar Photon spacecraft has successfully completed the third of seven planned orbit raising maneuvers, bringing the CAPSTONE spacecraft closer to the Moon.
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The CAPSTONE satellite integrated onto Rocket Lab’s Lunar Photon spacecraft before launch on the Electron rocket. (Photo: Business Wire)
Owned and operated by Advanced Space on behalf of NASA, the Cislunar Autonomous Positioning System Technology Operations and Navigation Experiment (CAPSTONE) CubeSat will be the first spacecraft to test the Near Rectilinear Halo Orbit (NRHO) around the Moon. This is the same orbit intended for NASA’s Gateway, a multipurpose Moon-orbiting station that will provide essential support for long-term astronaut lunar missions as part of the Artemis program.
The orbit raising maneuvers come after Rocket Lab successfully launched CAPSTONE to an initial parking orbit on June 28 with an Electron rocket from Launch Complex 1 in New Zealand. With Electron’s role in the mission now complete, Lunar Photon has taken over the reins, providing power, communications and in-space transportation to CAPSTONE for the next five-day mission phase.
Over these days, Lunar Photon’s HyperCurie engine will perform a series of orbit raising maneuvers by igniting periodically to increase Photon’s velocity, stretching its orbit into a prominent ellipse around Earth. Six days after launch, HyperCurie will ignite one final time, accelerating Photon Lunar to 24,500 mph (39,500 km/h) and setting it on a ballistic lunar transfer. Within 20 minutes of this final burn, Photon will release CAPSTONE into space for the first leg of the CubeSat’s solo flight. CAPSTONE’s journey to NRHO is expected to take around four months from this point. Assisted by the Sun’s gravity, CAPSTONE will reach a distance of 963,000 miles from Earth – more than three times the distance between Earth and the Moon – before being pulled back towards the Earth-Moon system.
Rocket Lab founder and CEO Peter Beck said the launch of the CAPSTONE mission was the culmination of two and a half years of work and it pushed the Electron launch vehicle to the limit. “Electron lifted its heaviest payload yet at 300 kg – the combined mass of Lunar Photon and CAPSTONE. We pushed the Rutherford engines harder than we ever have before and deployed Lunar Photon and CAPSTONE exactly where they needed to go to begin the next mission phase. Now it’s Lunar Photon’s show and we’re immensely proud of its performance so far. We’re really pushing the boundaries of what’s possible for interplanetary smallsat missions with CAPSTONE and it’s exciting to think about the possibilities it opens up for more cost-effective missions to Mars, Venus and beyond.”
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Founded in 2006, Rocket Lab is an end-to-end space company with an established track record of mission success. We deliver reliable launch services, satellite manufacture, spacecraft components, and on-orbit management solutions that make it faster, easier and more affordable to access space. Headquartered in Long Beach, California, Rocket Lab designs and manufactures the Electron small orbital launch vehicle and the Photon satellite platform and is developing the Neutron 8-ton payload class launch vehicle. Since its first orbital launch in January 2018, Rocket Lab’s Electron launch vehicle has become the second most frequently launched U.S. rocket annually and has delivered 147 satellites to orbit for private and public sector organizations, enabling operations in national security, scientific research, space debris mitigation, Earth observation, climate monitoring, and communications. Rocket Lab’s Photon spacecraft platform has been selected to support NASA missions to the Moon and Mars, as well as the first private commercial mission to Venus. Rocket Lab has three launch pads at two launch sites, including two launch pads at a private orbital launch site located in New Zealand and a second launch site in Virginia, USA which is expected to become operational in 2022. To learn more, visit www.rocketlabusa.com.
Get hype for the first images from NASA’s James Webb Space Telescope – Yahoo Movies Canada
Very soon, humanity will get to view the deepest images of the universe that have ever been captured. In two weeks, the $10 billion James Webb Space Telescope (JWST) — NASA’s super expensive, super powerful deep space optical imager — will release its first full-color images, and agency officials today suggested that they could just be the beginning.
“This is farther than humanity has ever looked before,” NASA Administrator Bill Nelson said during a media briefing Wednesday (he was calling in, as he had tested positive for COVID-19 the night before). “We’re only beginning to understand what Webb can and will do.”
NASA launched James Webb last December; ever since, it’s been conducting a specialized startup process that involves delicately tuning all 18 of its huge mirror segments. A few months ago, NASA shared a “selfie” marking the successful operations of the IR camera and primary mirrors. Earlier this month, the agency said the telescope’s first images will be ready for public debut at 10:30 AM ET on July 12.
One aspect of the universe that JWST will unveil is exoplanets, or planets outside our Solar System — specifically, their atmospheres. This is key to understanding whether there are other planets similar to ours in the universe, or if life can be found on planets under atmospheric conditions that differ from those found on Earth. And Thomas Zurbuchen, associate administrator for NASA’s Science Mission Directorate, confirmed that images of an exoplanet’s atmospheric spectrum will be shared with the public on July 12.
Essentially, James Webb’s extraordinary capacity to capture the infrared spectrum means that it will be able to detect small molecules like carbon dioxide. This will enable scientists to actually examine whether and how atmospheric compositions shape the capacity for life to emerge and develop on a planet.
NASA officials also shared more good news: The agency’s estimates of the excess fuel capability of the telescope were spot on, and JWST will be able to capture images of space for around 20 years.
“Not only will those 20 years allow us to go deeper into history and time, but we will go deeper into science because we will have the opportunity to learn and grow and make new observations,” NASA deputy administrator Pam Melroy said.
JWST has not had an easy ride to deep space. The entire project came very close to not happening at all, Nelson said, after it started running out of money and Congress considered canceling it entirely. It also faced numerous delays due to technical issues. Then, when it reached space, it was promptly pinged by a micrometeoroid, an event that surely made every NASA official shudder.
But overall, “it’s been an amazing six months,” Webb project manager Bill Ochs confirmed.
The Rings of Uranus and Neptune Could Help map Their Interiors – Universe Today
Mapping the interior of the ice giants is difficult, to say the least. Not only are they far away and therefore harder to observe, but their constant ice cover makes it extremely hard to detect what lies underneath. So scientists must devise more ingenious ways to see what’s inside them. A team from the University of Idaho, Cal Tech, Reed College, and the University of Arizona think they might have come up with a way – to look at the structure of Neptunes’ and Uranus’ rings.
This isn’t the first technique scientists have used, though. Previous efforts have attempted to use the common technique of photometry to detect oscillations on the planet’s surface. Those oscillations can then be correlated to the density of particular parts of the planet’s interior. While the technique worked well for Jupiter, the photometry data we have of the ice giants so far have proved insufficient to determine the same density profiles.
An alternative is using gravitational oscillations within the planet’s surface. In particular, there is a type of oscillation pattern known as a “normal mode.” This oscillation pattern happens when all parts of a system begin oscillating with the same sinusoidal frequency. And the gravitational effects of normal mode oscillations in the planet’s interior can be felt outside and reflected in the rings themselves.
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It also isn’t the first time patterns in a planet’s rings have been used to calculate its internal density. Saturn has a better-understood ring system than Uranus or Neptune, the two ice giants with known ring systems. Scientists have been performing seismological analyses on the Saturnian ring system for years using data from Voyager and Cassini. The result is a better understanding of some of the normal modes of the planet’s interior and, therefore, an estimate of the makeup of the planet’s core and the rotation rate of the bulk of its material.
Neptune and Uranus each have a series of different rings, though they are not as well studied as Saturn’s. Some of those rings of which are corralled by shepherd moons. But according to the new paper, the same density reflections of resonance waves evident in Saturn’s rings are likely present in the ice giant’s ring systems as well.
What’s more, the inner shepherd moons themselves might be affected by the same resonances. Some of the moons can even create their own resonances, such as one known as a Lindblad resonance. More typically seen on the scale of galaxies, Lindblad resonances are known for driving spiral density waves, which cause the “arms” that can be seen in many spiral galaxies. But at a much smaller scale, the same effect happens on planetary ring systems, including Saturn’s, and most likely, Neptune’s and Uranus’.
The problem with using these resonances reflected in the rings is one that often faces science – there’s not enough data. So far, no probe has stayed long enough to map out the details needed to see the full scope of the ring system. The paper’s authors and plenty of other researchers suggest that it’s time to send a probe to the ice giants to effectively map the ring systems, moons, and myriad other recently discovered objects that are so hard to observe from the Earth. But for now, that mission is still on the drawing board, so we’ll have to wait to fully understand the interiors and ring system of these cold, barren worlds. At least when we finally do send a probe out that way, we’ll have the mathematical framework to help shed light on these dark places.
A’Hearn et al – Ring Seismology of the Ice Giants Uranus and Neptune
UT – The Rings of Neptune
UT – Which Planets Have Rings?
UT – How Many Rings Does Uranus Have?
Artist impression of Uranus and its rings.
Credit – NRAO / AUI / NSF / S. Dagnello
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2022-06-29 | NDAQ:RKLB | Press Release | Rocket Lab USA Inc. – Stockhouse
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