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New nursing home cluster amid rising COVID-19 deaths and economic gloom – Canoe

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TORONTO — The COVID-19 death toll in Quebec more than doubled on Friday as the growing case load of infections in Canada surpassed 4,000 amid questions about how pandemic fatalities are counted and gloomy economic predictions.

Quebec saw 10 more people succumb to the virus in 24 hours, bringing the total number of reported deaths to 18. The province now has more than 2,000 cases — about twice as many as Ontario, which has recorded 18 COVID deaths among 993 cases. British Columbia has had 16 deaths, most elderly, while Manitoba saw its first, a woman in her 60s, on Friday.

Overall, 55 people have died in Canada as a result of COVID-19, health authorities reported. But the true number could be obscured.

Two residents of a nursing home in Bobcaygeon, Ont., who had symptoms of the flu-like illness, have died. Although neither was tested for the coronavirus, both deaths were assumed to be from COVID-19. Pinecrest Nursing Home said only three other residents were tested and confirmed positive, but 35 had symptoms.

The contagious virus is known to be particularly dangerous for the elderly and those with compromised health. Deadly outbreak clusters in nursing homes have also been reported in B.C. As at other long-term care facilities, residents at Pinecrest share rooms, making isolation difficult.

“This is truly a horrible time for the families and friends of the residents as well as our staff,” said Mary Carr, administrator of Pinecrest.

Tending to the ill has also stressed the system. B.C. has seen dozens of infections among nursing home staff. At least 14 staff at Pinecrest have tested positive; results for 16 others were pending, the local health unit said.

Governments and experts have urged people — in some cases backed by the threat of fines or jail time — to keep their distance from others. Travellers entering Canada must quarantine for 14 days. To drive home the message, Ontario residents received an emergency alert on their cellphones, radios and TVs at 2 p.m. Friday: “DO NOT visit stores, family or friends.”

Meanwile, members of the Canadian Armed Forces were told to be ready to respond immediately in a five-page letter from chief of the defence staff Gen. Jonathan Vance. The main message was for troops to stay healthy in advance of a possible call for help.

One glimmer of hope emerged from B.C., where data indicates the province’s COVID experience will likely resemble South Korea’s rather than brutally hit Italy. Dr. Bonnie Henry, B.C.’s provincial health officer, said she thinks the social distancing strategy is working and urged residents to keep at it.

However, experts aren’t saying the tide has turned. In Ontario, the associate chief medical officer of health said recovery numbers were expected to rise in the coming days.

Canada’s deputy chief public health officer also said he expected cases to keep rising for now. The anti-pandemic battle, Dr. Howard Njoo said, is far from over and could include a second wave.

“We’re in it for the long haul,” Njoo said. “It’s definitely months. Many months.”

The grim reality of the pandemic — only Nunavut has no confirmed infections — has meant a shrivelling economy and a sharply higher federal deficit as the government prepares to inject multiple billions to cushion the impact on workers.

Toronto-based Indigo Books and Music Inc. said it was now laying off 5,200 retail employees. The company, with around 8,000 employees, had been paying idled workers after it closed its stores last week.

Prime Minister Justin Trudeau said on Friday the government would cover 75 per cent of salaries for workers of qualifying small businesses affected by COVID-19, up from the 10 per cent announced earlier that critics said was too simply far too little.

The spending surge will turbo-charge the federal deficit, now projected to quadruple to $112.7 billion in the coming fiscal year. Parliament’s budget watchdog also predicted a 5.1 per cent contraction in this year’s economy, potentially the worst showing since 1962.

In an effort to keep cash flowing in the system, the Bank of Canada cut its key interest rate by 50 points to a minimalist 0.25 per cent.

The crisis has given police some unusual work. Officers in Hamilton charged a teenaged McDonald’s employee with fraud, mischief and uttering a forged document for allegedly faking a doctor’s note saying she had the virus. The outlet closed for several days for disinfecting. In New Brunswick, Kennebecasis regional police charged two men with assault for allegedly “purposely coughing in someone’s face while feeling ill.”

The latest numbers on COVID-19 in Canada

The latest numbers of confirmed and presumptive COVID-19 cases in Canada as of 10:08 p.m. ET on March 27, 2020:

There are 4,757 confirmed and presumptive cases in Canada.

— Quebec: 2,021 confirmed (including 18 deaths, 1 resolved)

— Ontario: 993 confirmed (including 18 deaths, 8 resolved)

— British Columbia: 792 confirmed (including 16 deaths, 275 resolved)

— Alberta: 542 confirmed (including 2 deaths, 33 resolved)

— Saskatchewan: 104 confirmed (including 3 resolved)

— Newfoundland and Labrador: 102 confirmed

— Nova Scotia: 90 confirmed

— New Brunswick: 45 confirmed

— Manitoba: 25 confirmed (including 1 death), 14 presumptive

— Repatriated Canadians: 13 confirmed

— Prince Edward Island: 11 confirmed

— Yukon: 4 confirmed

— Northwest Territories: 1 confirmed

— Nunavut: No confirmed cases

— Total: 4,757 (14 presumptive, 4,743 confirmed including 55 deaths, 320 resolved)

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Whooping cough is at a decade-high level in US

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MILWAUKEE (AP) — Whooping cough is at its highest level in a decade for this time of year, U.S. health officials reported Thursday.

There have been 18,506 cases of whooping cough reported so far, the Centers for Disease Control and Prevention said. That’s the most at this point in the year since 2014, when cases topped 21,800.

The increase is not unexpected — whooping cough peaks every three to five years, health experts said. And the numbers indicate a return to levels before the coronavirus pandemic, when whooping cough and other contagious illnesses plummeted.

Still, the tally has some state health officials concerned, including those in Wisconsin, where there have been about 1,000 cases so far this year, compared to a total of 51 last year.

Nationwide, CDC has reported that kindergarten vaccination rates dipped last year and vaccine exemptions are at an all-time high. Thursday, it released state figures, showing that about 86% of kindergartners in Wisconsin got the whooping cough vaccine, compared to more than 92% nationally.

Whooping cough, also called pertussis, usually starts out like a cold, with a runny nose and other common symptoms, before turning into a prolonged cough. It is treated with antibiotics. Whooping cough used to be very common until a vaccine was introduced in the 1950s, which is now part of routine childhood vaccinations. It is in a shot along with tetanus and diphtheria vaccines. The combo shot is recommended for adults every 10 years.

“They used to call it the 100-day cough because it literally lasts for 100 days,” said Joyce Knestrick, a family nurse practitioner in Wheeling, West Virginia.

Whooping cough is usually seen mostly in infants and young children, who can develop serious complications. That’s why the vaccine is recommended during pregnancy, to pass along protection to the newborn, and for those who spend a lot of time with infants.

But public health workers say outbreaks this year are hitting older kids and teens. In Pennsylvania, most outbreaks have been in middle school, high school and college settings, an official said. Nearly all the cases in Douglas County, Nebraska, are schoolkids and teens, said Justin Frederick, deputy director of the health department.

That includes his own teenage daughter.

“It’s a horrible disease. She still wakes up — after being treated with her antibiotics — in a panic because she’s coughing so much she can’t breathe,” he said.

It’s important to get tested and treated with antibiotics early, said Dr. Kris Bryant, who specializes in pediatric infectious diseases at Norton Children’s in Louisville, Kentucky. People exposed to the bacteria can also take antibiotics to stop the spread.

“Pertussis is worth preventing,” Bryant said. “The good news is that we have safe and effective vaccines.”

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AP data journalist Kasturi Pananjady contributed to this report.

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The Associated Press Health and Science Department receives support from the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

The Canadian Press. All rights reserved.

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Scientists show how sperm and egg come together like a key in a lock

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How a sperm and egg fuse together has long been a mystery.

New research by scientists in Austria provides tantalizing clues, showing fertilization works like a lock and key across the animal kingdom, from fish to people.

“We discovered this mechanism that’s really fundamental across all vertebrates as far as we can tell,” said co-author Andrea Pauli at the Research Institute of Molecular Pathology in Vienna.

The team found that three proteins on the sperm join to form a sort of key that unlocks the egg, allowing the sperm to attach. Their findings, drawn from studies in zebrafish, mice, and human cells, show how this process has persisted over millions of years of evolution. Results were published Thursday in the journal Cell.

Scientists had previously known about two proteins, one on the surface of the sperm and another on the egg’s membrane. Working with international collaborators, Pauli’s lab used Google DeepMind’s artificial intelligence tool AlphaFold — whose developers were awarded a Nobel Prize earlier this month — to help them identify a new protein that allows the first molecular connection between sperm and egg. They also demonstrated how it functions in living things.

It wasn’t previously known how the proteins “worked together as a team in order to allow sperm and egg to recognize each other,” Pauli said.

Scientists still don’t know how the sperm actually gets inside the egg after it attaches and hope to delve into that next.

Eventually, Pauli said, such work could help other scientists understand infertility better or develop new birth control methods.

The work provides targets for the development of male contraceptives in particular, said David Greenstein, a genetics and cell biology expert at the University of Minnesota who was not involved in the study.

The latest study “also underscores the importance of this year’s Nobel Prize in chemistry,” he said in an email.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

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