Pfizer says we need a 3rd COVID-19 vaccine. But experts aren’t so sure - Global News | Canada News Media
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Pfizer says we need a 3rd COVID-19 vaccine. But experts aren’t so sure – Global News

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As vaccine coverage blankets the country, ushering in hope for a return to normal, Pfizer announced Thursday that it’s prepping a COVID-19 booster shot to make sure things keep trending in the right direction.

There’s just one problem, according to experts. We might not actually need it.

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Preventing severe outcomes is the key to quashing COVID-19’s impact on our daily lives, according to the experts. Lockdowns and restrictions come into play when hospitalizations start to push the health care system’s capacity to its outer limits.

But with vaccines proving highly effective at preventing severe outcomes, experts say any conversations about boosters are still premature.

“I don’t think there’s good clinical evidence,” said Dr. Zain Chagla, an infectious disease specialist, on whether there’s data to back up Pfizer’s booster shot claims.






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Chagla added people “shouldn’t necessarily worry that these two shots are going to be useless in a few years.”

“These are the shots that are going to keep people out of hospital and health care from dying,” he said.

Chagla isn’t alone in his skepticism.

“The general feeling that it is not the right time for a third dose of the mRNA vaccines,” said John Moore, a virologist at Weill Cornell Medicine in New York.

“We’re not saying it should never happen, but now is not the time.”

While there are few studies showing how long protection provided by COVID-19 vaccines lasts, the early research is promising.

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A study published in the journal Nature in late June found mRNA-based vaccines create a more “persistent” germinal centre B cell response, which means that a person’s immune response to the jab is stronger and longer-lasting.

The researchers examined participants four months after they received their first Pfizer dose and found that the germinal centres in their lymph nodes, likened to a boot camp for immune cells, kept pumping out said cells to protect against the virus that causes COVID-19.

Despite this research, Pfizer is maintaining that it is “likely” that a third dose “may be needed within 6 to 12 months after full vaccination,” according to the company’s Thursday press release.

“While protection against severe disease remained high across the full 6 months, a decline in efficacy against symptomatic disease over time and the continued emergence of variants are expected.”






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The United States’ FDA and CDC released a joint statement responding to Pfizer’s claims this week — and in it, they said there’s currently no evidence supporting a recommendation of a booster shot.

“Americans who have been fully vaccinated do not need a booster shot at this time. FDA, CDC, and NIH are engaged in a science-based, rigorous process to consider whether or when a booster might be necessary,” the organizations wrote in the statement.

They said this process will look at laboratory data, clinical trial data and, potentially, data from specific pharmaceutical companies — but the research will “not rely on those data exclusively.”

“We continue to review any new data as it becomes available and will keep the public informed. We are prepared for booster doses if and when the science demonstrates that they are needed,” the statement read.

Health Canada struck a similar tone in their own statement about the issue, which they sent to Global News.

“Currently, people who are fully vaccinated are protected from severe disease and death, including from the variants currently circulating,” read the statement.

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But Health Canada is open to the possibility of booster shots if the evidence supports it, they said, adding that the longevity of the immune response to existing vaccines is “currently being studied.”

And while Pfizer’s vaccine efforts have been hugely helpful in quashing the spread of COVID-19, they’ve also proven to be extremely lucrative for the company.

In the first three months of 2021 alone, the COVID-19 vaccine raked in $3.5 billion USD ($4.3 billion CAD) in revenue for the pharmaceutical giant, according to their reported first quarter earnings.






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Some experts wonder if Pfizer’s arguments in favour of a booster shot could have a financial motivation.

“It’s being (said) that Pfizer is being somewhat opportunistic,” said Moore.

“Pushing the idea of vaccine boosters will, of course, greatly increase vaccine sales.”

Chagla added that these vaccines are some of “the most valuable assets on Earth right now” and that keeping them in the “limelight” likely “plays a role” in what’s happening here.

There may be a need for a booster eventually, Chagla added, but “there is something to be said about the fact that we’re talking about boosters for variants, without a global vaccine plan.”


The threat of vaccine inequality

As for Pfizer’s claims that the “continued emergence of variants are expected,” experts say there’s a much bigger threat when it comes to deadly mutations of the virus: the lack of vaccine coverage around the world.

It comes down to how variants emerge, according to Chagla.

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As a virus spreads, it replicates. With each opportunity the virus has to replicate, it has more and more chances to make a mistake. Sometimes, those mistakes end up being advantageous for the virus — either allowing it to spread more easily, or potentially making the virus more severe.

The more COVID-19 spreads, the more opportunities it has to replicate and mutate. That means the biggest risk for the creation of variants is the large pockets of the world where uncontrolled spread is still occurring, Chagla explained.

“The big things that lead to variants are large unvaccinated populations, particularly ones where health systems are really poor and patients with immune conditions,” he said.

And while Canada’s current levels of vaccine coverage are sufficient to stave off the worst outcomes of the pandemic, Moore noted that many countries in the world aren’t so privileged.

“There is an ethical concern about prioritizing dose three for Americans over doses one and two for the rest of the world,” he said.

The WHO has warned that vaccine coverage in some parts of the world remains worryingly low.

“In some parts of the world, the vaccination rates, even at one dose, are one per cent, two per cent, three per cent, five per cent,” said Dr. Peter Singer, an advisor with the WHO, in a Wednesday interview with Global News.

“To be safe is for this fire to be put out everywhere in the world, because otherwise, if it’s burning anywhere, it’s going to be casting off embers that are going to ignite flames everywhere.”






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Chagla said that as long as the world prioritizes new variant-focused vaccines over getting those first and second doses rolled out around the world, we’ll all be playing catch-up in preventing COVID-19’s spread.

“We can build vaccines to make ourselves more protected against the evolution of this virus,” Chagla said.

“But if we’re not addressing the root cause of the evolution of this virus, then we’re going to be left with chasing our tails over and over and over again.”

— with files from Global News’ David Lao and Mike Le Couteur

© 2021 Global News, a division of Corus Entertainment Inc.

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Telus prioritizing ‘most important customers,’ avoiding ‘unprofitable’ offers: CFO

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Telus Corp. says it is avoiding offering “unprofitable” discounts as fierce competition in the Canadian telecommunications sector shows no sign of slowing down.

The company said Friday it had fewer net new customers during its third quarter compared with the same time last year, as it copes with increasingly “aggressive marketing and promotional pricing” that is prompting more customers to switch providers.

Telus said it added 347,000 net new customers, down around 14.5 per cent compared with last year. The figure includes 130,000 mobile phone subscribers and 34,000 internet customers, down 30,000 and 3,000, respectively, year-over-year.

The company reported its mobile phone churn rate — a metric measuring subscribers who cancelled their services — was 1.09 per cent in the third quarter, up from 1.03 per cent in the third quarter of 2023. That included a postpaid mobile phone churn rate of 0.90 per cent in its latest quarter.

Telus said its focus is on customer retention through its “industry-leading service and network quality, along with successful promotions and bundled offerings.”

“The customers we have are the most important customers we can get,” said chief financial officer Doug French in an interview.

“We’ve, again, just continued to focus on what matters most to our customers, from a product and customer service perspective, while not loading unprofitable customers.”

Meanwhile, Telus reported its net income attributable to common shares more than doubled during its third quarter.

The telecommunications company said it earned $280 million, up 105.9 per cent from the same three-month period in 2023. Earnings per diluted share for the quarter ended Sept. 30 was 19 cents compared with nine cents a year earlier.

It reported adjusted net income was $413 million, up 10.7 per cent year-over-year from $373 million in the same quarter last year. Operating revenue and other income for the quarter was $5.1 billion, up 1.8 per cent from the previous year.

Mobile phone average revenue per user was $58.85 in the third quarter, a decrease of $2.09 or 3.4 per cent from a year ago. Telus said the drop was attributable to customers signing up for base rate plans with lower prices, along with a decline in overage and roaming revenues.

It said customers are increasingly adopting unlimited data and Canada-U.S. plans which provide higher and more stable ARPU on a monthly basis.

“In a tough operating environment and relative to peers, we view Q3 results that were in line to slightly better than forecast as the best of the bunch,” said RBC analyst Drew McReynolds in a note.

Scotiabank analyst Maher Yaghi added that “the telecom industry in Canada remains very challenging for all players, however, Telus has been able to face these pressures” and still deliver growth.

The Big 3 telecom providers — which also include Rogers Communications Inc. and BCE Inc. — have frequently stressed that the market has grown more competitive in recent years, especially after the closing of Quebecor Inc.’s purchase of Freedom Mobile in April 2023.

Hailed as a fourth national carrier, Quebecor has invested in enhancements to Freedom’s network while offering more affordable plans as part of a set of commitments it was mandated by Ottawa to agree to.

The cost of telephone services in September was down eight per cent compared with a year earlier, according to Statistics Canada’s most recent inflation report last month.

“I think competition has been and continues to be, I’d say, quite intense in Canada, and we’ve obviously had to just manage our business the way we see fit,” said French.

Asked how long that environment could last, he said that’s out of Telus’ hands.

“What I can control, though, is how we go to market and how we lead with our products,” he said.

“I think the conditions within the market will have to adjust accordingly over time. We’ve continued to focus on digitization, continued to bring our cost structure down to compete, irrespective of the price and the current market conditions.”

Still, Canada’s telecom regulator continues to warn providers about customers facing more charges on their cellphone and internet bills.

On Tuesday, CRTC vice-president of consumer, analytics and strategy Scott Hutton called on providers to ensure they clearly inform their customers of charges such as early cancellation fees.

That followed statements from the regulator in recent weeks cautioning against rising international roaming fees and “surprise” price increases being found on their bills.

Hutton said the CRTC plans to launch public consultations in the coming weeks that will focus “on ensuring that information is clear and consistent, making it easier to compare offers and switch services or providers.”

“The CRTC is concerned with recent trends, which suggest that Canadians may not be benefiting from the full protections of our codes,” he said.

“We will continue to monitor developments and will take further action if our codes are not being followed.”

French said any initiative to boost transparency is a step in the right direction.

“I can’t say we are perfect across the board, but what I can say is we are absolutely taking it under consideration and trying to be the best at communicating with our customers,” he said.

“I think everyone looking in the mirror would say there’s room for improvement.”

This report by The Canadian Press was first published Nov. 8, 2024.

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TC Energy cuts cost estimate for Southeast Gateway pipeline project in Mexico

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CALGARY – TC Energy Corp. has lowered the estimated cost of its Southeast Gateway pipeline project in Mexico.

It says it now expects the project to cost between US$3.9 billion and US$4.1 billion compared with its original estimate of US$4.5 billion.

The change came as the company reported a third-quarter profit attributable to common shareholders of C$1.46 billion or $1.40 per share compared with a loss of C$197 million or 19 cents per share in the same quarter last year.

Revenue for the quarter ended Sept. 30 totalled C$4.08 billion, up from C$3.94 billion in the third quarter of 2023.

TC Energy says its comparable earnings for its latest quarter amounted to C$1.03 per share compared with C$1.00 per share a year earlier.

The average analyst estimate had been for a profit of 95 cents per share, according to LSEG Data & Analytics.

This report by The Canadian Press was first published Nov. 7, 2024.

Companies in this story: (TSX:TRP)

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BCE reports Q3 loss on asset impairment charge, cuts revenue guidance

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BCE Inc. reported a loss in its latest quarter as it recorded $2.11 billion in asset impairment charges, mainly related to Bell Media’s TV and radio properties.

The company says its net loss attributable to common shareholders amounted to $1.24 billion or $1.36 per share for the quarter ended Sept. 30 compared with a profit of $640 million or 70 cents per share a year earlier.

On an adjusted basis, BCE says it earned 75 cents per share in its latest quarter compared with an adjusted profit of 81 cents per share in the same quarter last year.

“Bell’s results for the third quarter demonstrate that we are disciplined in our pursuit of profitable growth in an intensely competitive environment,” BCE chief executive Mirko Bibic said in a statement.

“Our focus this quarter, and throughout 2024, has been to attract higher-margin subscribers and reduce costs to help offset short-term revenue impacts from sustained competitive pricing pressures, slow economic growth and a media advertising market that is in transition.”

Operating revenue for the quarter totalled $5.97 billion, down from $6.08 billion in its third quarter of 2023.

BCE also said it now expects its revenue for 2024 to fall about 1.5 per cent compared with earlier guidance for an increase of zero to four per cent.

The company says the change comes as it faces lower-than-anticipated wireless product revenue and sustained pressure on wireless prices.

BCE added 33,111 net postpaid mobile phone subscribers, down 76.8 per cent from the same period last year, which was the company’s second-best performance on the metric since 2010.

It says the drop was driven by higher customer churn — a measure of subscribers who cancelled their service — amid greater competitive activity and promotional offer intensity. BCE’s monthly churn rate for the category was 1.28 per cent, up from 1.1 per cent during its previous third quarter.

The company also saw 11.6 per cent fewer gross subscriber activations “due to more targeted promotional offers and mobile device discounting compared to last year.”

Bell’s wireless mobile phone average revenue per user was $58.26, down 3.4 per cent from $60.28 in the third quarter of the prior year.

This report by The Canadian Press was first published Nov. 7, 2024.

Companies in this story: (TSX:BCE)

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