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Pfizer’s COVID-19 vaccine effective at preventing severe outcomes from 2 variants: studies – Global News

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Pfizer-BioNTech’s COVID-19 vaccine was found to be extremely effective at preventing severe outcomes — like hospitalization and death — caused by more transmissible or vaccine-resistant variants, according to two recently-published studies.

Published on Wednesday, the two studies which focused on the vaccine’s usage in Israel and Qatar found that Pfizer’s shot gave near-total protection against the worst possible outcomes of contracting the virus from either the B.1.1.7. variant first found in the U.K. and the B.1.351 variant that was discovered in South Africa.

Researchers previously found the B.1.1.7 variant to be as much as 65 per cent more transmissible than the original, dominant version of COVID-19, while the B.1.351 was found to carry mutations that allowed the variant to be more resistant to vaccines.

Read more:
Pfizer COVID-19 vaccine approved for Canadians 12 and over, Health Canada says

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The Qatar-based study, published in the New England Journal of Medicine, used data from the country’s national COVID-19 database, which is comprised of over 265,000 people who received two doses of the Pfizer shot as of March 31.

Around mid-March, about 50 per cent of Qatar’s COVID-19 cases were caused by the B.1.351 variant and 44.5 per cent identified as the B.1.1.7. variant, according to the study.

Overall, the researchers found that the Pfizer shot was 97.4 per cent effective at preventing “severe, critical or fatal disease” from any form of COVID-19, and that it was 100 per cent effective in the same category against both the U.K. and South African variants.






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Global National: May 6


Global National: May 6

In terms of protection against infection, the Pfizer shot was 87 to 89.5 per cent effect at preventing infections from B.1.1.7. for those who were two weeks past their second jab. The vaccine, however, was less effective at preventing infection against the B.1.351 variant, offering as much as 75 per cent protection two weeks after the second jab.

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The other study, which was published in The Lancet and conducted by Israel’s Ministry of Health, found, based on data analyzing Israel’s rollout of the Pfizer shot, that it offered 95 per cent protection against COVID-19 infection seven days after the second jab.

Until the start of April, the analysis used data from more than 5 million people — over 70 per cent of the population — that received two doses of the Pfizer shot.

Read more:
Canada set to receive 2M Pfizer doses this week as company ramps up delivery

Researchers there found that two doses gave over 95 per cent protection against infection from the U.K. variant, and over 96 per cent protection against death one week after getting the second dose. After 14 days, both of those numbers increased to 96.5 per cent and 98 per cent, respectively

It should be noted, however, that during the study’s period, over 232,000 confirmed cases of COVID-19 were found — of which 95 per cent were tested to be just the B.1.1.7. variant.

The researchers said that vaccine effectiveness against the South African variant could not be estimated in their study “because of the small number of B.1.351 infections identified in Israel during the study period.”

The research, however, revealed that protection was found to be significantly lower if recipients were given just a single dose of the Pfizer vaccine instead of two.

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Protection against infection was found to be 57.7 per cent between seven and 14 days after receiving the first dose, while protection against death was 77 per cent during the same period.

“Importantly, the study shows that two doses of the vaccine significantly increase levels of immunity and protection. This is why it is important that people get both doses,” said Dr. Jonathan Ball, a professor of molecular virology at the University of Nottingham via London’s Science Media Centre.

© 2021 Global News, a division of Corus Entertainment Inc.

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Roots sees room for expansion in activewear, reports $5.2M Q2 loss and sales drop

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TORONTO – Roots Corp. may have built its brand on all things comfy and cosy, but its CEO says activewear is now “really becoming a core part” of the brand.

The category, which at Roots spans leggings, tracksuits, sports bras and bike shorts, has seen such sustained double-digit growth that Meghan Roach plans to make it a key part of the business’ future.

“It’s an area … you will see us continue to expand upon,” she told analysts on a Friday call.

The Toronto-based retailer’s push into activewear has taken shape over many years and included several turns as the official designer and supplier of Team Canada’s Olympic uniform.

But consumers have had plenty of choice when it comes to workout gear and other apparel suited to their sporting needs. On top of the slew of athletic brands like Nike and Adidas, shoppers have also gravitated toward Lululemon Athletica Inc., Alo and Vuori, ramping up competition in the activewear category.

Roach feels Roots’ toehold in the category stems from the fit, feel and following its merchandise has cultivated.

“Our product really resonates with (shoppers) because you can wear it through multiple different use cases and occasions,” she said.

“We’ve been seeing customers come back again and again for some of these core products in our activewear collection.”

Her remarks came the same day as Roots revealed it lost $5.2 million in its latest quarter compared with a loss of $5.3 million in the same quarter last year.

The company said the second-quarter loss amounted to 13 cents per diluted share for the quarter ended Aug. 3, the same as a year earlier.

In presenting the results, Roach reminded analysts that the first half of the year is usually “seasonally small,” representing just 30 per cent of the company’s annual sales.

Sales for the second quarter totalled $47.7 million, down from $49.4 million in the same quarter last year.

The move lower came as direct-to-consumer sales amounted to $36.4 million, down from $37.1 million a year earlier, as comparable sales edged down 0.2 per cent.

The numbers reflect the fact that Roots continued to grapple with inventory challenges in the company’s Cooper fleece line that first cropped up in its previous quarter.

Roots recently began to use artificial intelligence to assist with daily inventory replenishments and said more tools helping with allocation will go live in the next quarter.

Beyond that time period, the company intends to keep exploring AI and renovate more of its stores.

It will also re-evaluate its design ranks.

Roots announced Friday that chief product officer Karuna Scheinfeld has stepped down.

Rather than fill the role, the company plans to hire senior level design talent with international experience in the outdoor and activewear sectors who will take on tasks previously done by the chief product officer.

This report by The Canadian Press was first published Sept. 13, 2024.

Companies in this story: (TSX:ROOT)

The Canadian Press. All rights reserved.

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Talks on today over HandyDART strike affecting vulnerable people in Metro Vancouver

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VANCOUVER – Mediated talks between the union representing HandyDART workers in Metro Vancouver and its employer, Transdev, are set to resume today as a strike that has stopped most services drags into a second week.

No timeline has been set for the length of the negotiations, but Joe McCann, president of the Amalgamated Transit Union Local 1724, says they are willing to stay there as long as it takes, even if talks drag on all night.

About 600 employees of the door-to-door transit service for people unable to navigate the conventional transit system have been on strike since last Tuesday, pausing service for all but essential medical trips.

Hundreds of drivers rallied outside TransLink’s head office earlier this week, calling for the transportation provider to intervene in the dispute with Transdev, which was contracted to oversee HandyDART service.

Transdev said earlier this week that it will provide a reply to the union’s latest proposal on Thursday.

A statement from the company said it “strongly believes” that their employees deserve fair wages, and that a fair contract “must balance the needs of their employees, clients and taxpayers.”

This report by The Canadian Press was first published Sept. 12, 2024.

The Canadian Press. All rights reserved.

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Transat AT reports $39.9M Q3 loss compared with $57.3M profit a year earlier

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MONTREAL – Travel company Transat AT Inc. reported a loss in its latest quarter compared with a profit a year earlier as its revenue edged lower.

The parent company of Air Transat says it lost $39.9 million or $1.03 per diluted share in its quarter ended July 31.

The result compared with a profit of $57.3 million or $1.49 per diluted share a year earlier.

Revenue in what was the company’s third quarter totalled $736.2 million, down from $746.3 million in the same quarter last year.

On an adjusted basis, Transat says it lost $1.10 per share in its latest quarter compared with an adjusted profit of $1.10 per share a year earlier.

Transat chief executive Annick Guérard says demand for leisure travel remains healthy, as evidenced by higher traffic, but consumers are increasingly price conscious given the current economic uncertainty.

This report by The Canadian Press was first published Sept. 12, 2024.

Companies in this story: (TSX:TRZ)

The Canadian Press. All rights reserved.

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