Threat posed by H5N1 bird flu deepens, as public health authorities delay action | Canada News Media
Connect with us

Health

Threat posed by H5N1 bird flu deepens, as public health authorities delay action

Published

 on

Since the highly pathogenic avian influenza (H5N1 bird flu) was first detected among dairy cows in late March, a total of 132 herds across 12 states have now officially been impacted. In the last 30 days, an additional 65 infected herds have been confirmed across eight states. Despite repeated assurances given by the federal government that every resource is being utilized to eliminate the threat, scientists are increasingly concerned that far too little is actually being done to protect humanity from another pandemic.

Number of dairy cow herds infected with H5N1 weekly in the US (Source: USDA) [Photo: USDA/WSWS]

To date, the Centers for Disease Control and Prevention (CDC) has only tested 51 people potentially exposed to H5N1, a figure which has remained essentially static since the outbreak was detected. This only confirms in the negative that little has been done to conduct surveillance, testing, and serological studies of communities where people and livestock live in close proximity, which are necessary for epidemiologists to comprehend the scope of the ongoing threat.

More recently, a Michigan initiative is underway with the support of the US Food and Drug Administration (FDA) to begin testing a wider range of dairy products and a human serology study to assess the impact on workers after exposure to sick cows. The CDC stated that the objective of these efforts is to determine the efficacy of antivirals on the circulating clade of the bird flu, understanding infection in people, estimating the incubation period and potential mechanisms to mitigate the possibility of an H5N1 pandemic.

In a recent social media post on Twitter/X, molecular biologist and social science journalist Kai Kupferschmidt commented on research being conducted in a high security lab in Germany where cows were infected with the H5N1 strain circulating in US dairy cows and strains from H5N1-infected wild birds. He wrote, “In both cases they infected the udders directly through the teats and in both cases the animals got sick. They showed clear signs of disease such as a sharp drop in milk production, changes in milk consistency and fever.”

A dairy cow. [Photo: Keith Weller/USDA]

Kupferschmidt noted that the preliminary results imply that wherever H5N1 is circulating, the virus can spill over into cows. The researchers also indicated that transmission among cows may be a result of human activity, in which contaminated equipment is causing transmission through direct contact. However, he said that more research is needed on the potential for cow-to-cow transmission, and he is awaiting the results of the research to be published soon.

In a special report published in STAT News, based on interviews with numerous experts and federal representatives, the authors concluded,

The country still does not have a sufficient testing infrastructure in place, nor a full understanding of how the virus is moving within herds and to new herds, experts say. Government officials also have not secured the cooperation from farmers and dairy workers that would be required to rein in the outbreak.

In another interview, former CDC director in the Trump administration Dr. Robert Redfield said, “I really do think it’s very likely that we will, at some time, it’s not a question of if, it’s more of a question of when we will have a bird flu pandemic.” He added that a bird flu pandemic would have considerably greater mortality than COVID-19, placing the figure at “somewhere between 25 and 50 percent mortality,” while the death rate for COVID-19 has been estimated at 0.6 percent.

As CDC director under Trump, Redfield botched the initial rollout of mass testing and contact tracing and was instrumental in the dismantling of public health infrastructure. He discouraged COVID-19 testing, advocated the deadly reopening of schools in the fall of 2020, lied about the airborne nature of the virus and denigrated masking. One must ask, when the next pandemic ignites, will Redfield call for an elimination strategy or endorse a “forever bird flu” policy?

Redfield’s decades of experience in public health and discussions with experts on flu viruses and the evolution of H5N1 over nearly three decades underscore the significance of his warnings. That this particular virus has insinuated itself into livestock and animals, such as cats and mice, known to habitate homes and farms, indicates the potential ability for the virus to mutate further and potentially evolve to easily infect people via respiratory pathways.

The case of SARS-CoV-2, the virus that causes COVID-19, and its emergence from the wild animal market in Wuhan, underscores these concerns. According to the EcoHealth Alliance’s 2022 study published in Nature, the authors found an abundance of SARS-and SARS-CoV-2-related bat coronaviruses across a broad geographic region in Southern China, home to 300 million people. Their estimates indicated approximately 66,000 people were exposed to these viruses annually.

Given that 16 million people were engaged in the wild animal trade industry in China at that time, estimated at $73 billion by the Chinese Academy of Engineering, brings to the fore the connection between economics, human activity, the need for sources of alternative proteins given the prohibitive cost of basic foods and the threat of pandemics.

That SARS-CoV-2 has the ability to infect a wide array of animals besides humans suggests that the virus had already been well established in intermediary hosts before it had erupted in a self-sustaining outbreak in December 2019. Such is the case with H5N1 clade 2.3.4.4b, which emerged in 2020 when the virus reassorted between wild birds and poultry and has led to the mass killing of hundreds of millions of birds, as well as dozens of animal species.

As the STAT News report highlights, private dairy farms and agricultural businesses see the need for a thorough public health investigation into the outbreak of H5N1 as an intrusion into their profit-making. That is why the statement by the USDA—“The actions we have taken to limit movements, improve biosecurity and encourage testing are expected to establish the foundation for eliminating this virus from the dairy herd”—must be taken with a massive grain of salt. While the USDA advocates for a sound scientific approach, it is ultimately invested in the corporate structure.

It is precisely because the US cattle industry is struggling to break even that the call to investigate H5N1 on their farms and among their workers and livestock is met with trepidation. According to the Federal Reserve Bank of Kansas City, cattle inventories are at historic lows. A March 29, 2024 report notes:

Cattle producers may face challenges maintaining or restocking herds, as higher interest expenses on cattle and input purchases in 2022-23 have constrained profit margins. Although feed costs have decreased slightly, higher costs for financing and other operating expenses could continue to put pressure on cattle production and profitability.

The STAT News piece indicates the cool response from farmers to public health measures that might cut into their profits, noting:

But the government’s own data indicate the efforts have holes large enough for the virus to run through. In one USDA survey, 60 percent of farms acknowledged moving cows within a state even after the animals had started showing symptoms of infection. Federal officials have acknowledged they’re not getting much cooperation from dairy producers and workers.

Despite the clear and growing dangers of a bird flu pandemic, there is now a repeated refrain that the threat posed thus far remains low. However, one should recall a report from 2010 by influenza virologist Professor Yoshihiro Kawaoka and colleagues from the School of Veterinary Medicine at the University of Wisconsin-Madison, studying potential reassortments between co-circulating H5N1 and human H3N2 influenza viruses, which noted:

Our data demonstrate that the gene segments of these two viruses are largely compatible, resulting in 184 reassortant viruses with different replicative abilities. Pathogenicity experiments performed with 75 H5 reassortant viruses showed that 22 viruses were more pathogenic for mice than the parental SK06 virus. Strikingly, three viruses exhibited substantial lethality for mice.

As H5N1 continues to spread deeper into US dairy farms, one can ask how might the flu season evolve if these two flu viruses co-circulate, thereby allowing H5N1 to gain respiratory transmission potential with its pathogenicity intact? Are such possibilities being considered, and what preparations should US and World Health Organization (WHO) authorities undertake to prevent such a catastrophic development?

To suggest, as many political mouthpieces have, that the US and the world will somehow be prepared to vaccinate their way out of a pandemic scenario is utterly depraved and dangerous. As Rick Bright, former director of the Biomedical Advanced R&D Authority, recently told Fortune, “A head-in-the-sand approach to influenza readiness will not serve the public well when there is a need to respond to an influenza pandemic. The time to commence serious action is now, not when the country is staring down the barrel of a full pandemic.”

Source link

Continue Reading

Health

Women in states with bans are getting abortions at similar rates as under Roe, report says

Published

 on

 

Women living in states with abortion bans obtained the procedure in the second half of 2023 at about the same rate as before the U.S. Supreme Court overturned Roe v. Wade, according to a report released Tuesday.

Women did so by traveling out of state or by having prescription abortion pills mailed to them, according to the #WeCount report from the Society of Family Planning, which advocates for abortion access. They increasingly used telehealth, the report found, as medical providers in states with laws intended to protection them from prosecution in other states used online appointments to prescribe abortion pills.

“The abortion bans are not eliminating the need for abortion,” said Ushma Upadhyay, a University of California, San Francisco public health social scientist and a co-chair of the #WeCount survey. “People are jumping over these hurdles because they have to.”

Abortion patterns have shifted

The #WeCount report began surveying abortion providers across the country monthly just before Roe was overturned, creating a snapshot of abortion trends. In some states, a portion of the data is estimated. The effort makes data public with less than a six-month lag, giving a picture of trends far faster than the U.S. Centers for Disease Control and Prevention, whose most recent annual report covers abortion in 2021.

The report has chronicled quick shifts since the Supreme Court’s Dobbs v. Jackson Women’s Health Organization ruling that ended the national right to abortion and opened the door to enforcement of state bans.

The number of abortions in states with bans at all stages of pregnancy fell to near zero. It also plummeted in states where bans kick in around six weeks of pregnancy, which is before many women know they’re pregnant.

But the nationwide total has been about the same or above the level from before the ruling. The study estimates 99,000 abortions occurred each month in the first half of 2024, up from the 81,000 monthly from April through December 2022 and 88,000 in 2023.

One reason is telehealth, which got a boost when some Democratic-controlled states last year began implementing laws to protect prescribers. In April 2022, about 1 in 25 abortions were from pills prescribed via telehealth, the report found. In June 2024, it was 1 in 5.

The newest report is the first time #WeCount has broken down state-by-state numbers for abortion pill prescriptions. About half the telehealth abortion pill prescriptions now go to patients in states with abortion bans or restrictions on telehealth abortion prescriptions.

In the second half of last year, the pills were sent to about 2,800 women each month in Texas, more than 1,500 in Mississippi and nearly 800 in Missouri, for instance.

Travel is still the main means of access for women in states with bans

Data from another group, the Guttmacher Institute, shows that women in states with bans still rely mostly on travel to get abortions.

By combining results of the two surveys and comparing them with Guttmacher’s counts of in-person abortions from 2020, #WeCount found women in states with bans throughout pregnancy were getting abortions in similar numbers as they were in 2020. The numbers do not account for pills obtained from outside the medical system in the earlier period, when those prescriptions most often came from abroad. They also do not tally people who received pills but did not use them.

West Virginia women, for example, obtained nearly 220 abortions monthly in the second half of 2023, mostly by traveling — more than in 2020, when they received about 140 a month. For Louisiana residents, the monthly abortion numbers were about the same, with just under 700 from July through December 2023, mostly through shield laws, and 635 in 2020. However, Oklahoma residents obtained fewer abortions in 2023, with the monthly number falling to under 470 from about 690 in 2020.

Telehealth providers emerged quickly

One of the major providers of the telehealth pills is the Massachusetts Abortion Access Project. Cofounder Angel Foster said the group prescribed to about 500 patients a month, mostly in states with bans, from its September 2023 launch through last month.

The group charged $250 per person while allowing people to pay less if they couldn’t afford that. Starting this month, with the help of grant funding that pays operating costs, it’s trying a different approach: Setting the price at $5 but letting patients know they’d appreciate more for those who can pay it. Foster said the group is on track to provide 1,500 to 2,000 abortions monthly with the new model.

Foster called the Supreme Court’s 2020 decision “a human rights and social justice catastrophe” while also saying that “there’s an irony in what’s happened in the post-Dobbs landscape.”

“In some places abortion care is more accessible and affordable than it was,” she said.

There have no major legal challenges of shield laws so far, but abortion opponents have tried to get one of the main pills removed from the market. Earlier this year, the U.S. Supreme Court unanimously preserved access to the drug, mifepristone, while finding that a group of anti-abortion doctors and organizations did not have the legal right to challenge the 2000 federal approval of the drug.

This month, three states asked a judge for permission to file a lawsuit aimed at rolling back federal decisions that allowed easier access to the pill — including through telehealth.

Source link

Continue Reading

Health

How many smoke-related deaths from wildfires are linked to climate change every year?

Published

 on

 

Climate change may be contributing to thousands more wildfire smoke-related deaths every year than in previous decades, a new study suggests — results a Canadian co-author says underline the urgency of reducing planet-warming emissions.

The international study published Monday is one of the most rigorous yet in determining just how much climate change can be linked to wildfire smoke deaths around the world, said Sian Kou-Giesbrecht, an assistant professor at Dalhousie University.

“What stands out to me is that this proportion is increasing just so much. I think that it really kind of attests to just how much we need to take targeted action to reducing greenhouse-gas emissions,” she said in an interview.

The study estimates, using mathematical modeling, that about 12,566 annual wildfire smoke-related deaths in the 2010s were linked to climate change, up from about 669 in the 1960s, when far less carbon dioxide was concentrated in the atmosphere.

Translated to a proportion of wildfire smoke mortality overall, the study estimates about 13 per cent of estimated excessdeaths in the 2010s were linked to climate change, compared to about 1.2 per cent in the 1960s.

“Adapting to the critical health impacts of fires is required,” read the study, published in the peer-reviewed journal Nature Climate Change.

While wildfires are a natural part of the boreal forest ecosystem, a growing number of studies have documented how climate change, driven by the burning of fossil fuels, is making them larger and more intense — and contributing more to air pollution.

The same research group is behind another study published in the same journal Monday that suggests climate change increased the global area burned by wildfire by about 16 per cent from 2003 to 2019.

Those climate-fuelled fires then churn out more fine particle pollution, known as PM2.5, that’s tiny enough to get deep into the lungs — and in the long run can have serious health effects.

The study that estimated the scale of those effects is based on modeling, not historical data about reported deaths from air pollution.

Researchers used established public-health metrics for when pollution is thought to contribute to mortality, then figured out the extent to which wildfire smoke may have played a role in that overall exposure to arrive at the estimates.

Meanwhile, Health Canada estimates that between 2013 and 2018, up to 240 Canadians died every year due to short-term exposure to wildfire air pollution.

Kou-Giesbrecht said Monday’s study did not find that climate change had a major influence on the number of smoke-related deaths from Canada’s boreal wildfires.

She suggested that’s likely due to the country’s relatively small population size, and how tricky it is to model forest fires in the region, given its unique mix of shrubs and peat.

But she also noted that a stretch of devastating Canadian wildfire seasons over the past several years was not captured in the study, and she expects future research could find a bigger increase in deaths and public-health problems linked to climate change.

The most affected regions in the study were South America, Australia and Europe.

Kou-Giesbrecht said the more studies that uncover the link between climate change and disasters as “tangible” as wildfires, the more the case for “drastic climate action” will be bolstered.

“I think that the more and more evidence that we have to support the role of climate change in shaping the past 100 years, and knowing that it will continue to shape the next 100 years, is really important,” she said.

“And I find that personally interesting, albeit scary.”

The study used three highly complex models to estimate the relationship between climate change, land use and fire.

The models, which each contain thousands upon thousands of equations, compare what wildfires look like in the current climate to what they may have looked like in pre-industrial times, before humans started to burn vast amounts of fossil fuels.

The researchers used the models to calculate gas and aerosol emissions from wildfires between 1960 and 2019, and then make estimates about annual smoke-related deaths.

The type of methodology used by Monday’s studies, known as attribution science, is considered one of the fastest-growing fields of climate science. It is bolstered in part by major strides in computing power.

This report by The Canadian Press was first published Oct. 21, 2024.

Source link

Continue Reading

Health

Some Ontario docs now offering RSV shot to infants with Quebec rollout set for Nov.

Published

 on

 

Some Ontario doctors have started offering a free shot that can protect babies from respiratory syncytial virus while Quebec will begin its immunization program next month.

The new shot called Nirsevimab gives babies antibodies that provide passive immunity to RSV, a major cause of serious lower respiratory tract infections for infants and seniors, which can cause bronchiolitis or pneumonia.

Ontario’s ministry of health says the shot is already available at some doctor’s offices in Ontario with the province’s remaining supply set to arrive by the end of the month.

Quebec will begin administering the shots on Nov. 4 to babies born in hospitals and delivery centers.

Parents in Quebec with babies under six months or those who are older but more vulnerable to infection can also book immunization appointments online.

The injection will be available in Nunavut and Yukon this fall and winter, though administration start dates have not yet been announced.

This report by The Canadian Press was first published Oct. 21, 2024.

-With files from Nicole Ireland

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

The Canadian Press. All rights reserved.

Source link

Continue Reading

Trending

Exit mobile version