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Unvaccinated people 11 times more likely to die from COVID – CDC report – Barrie 360

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Alexander Tin – CBS News

Unvaccinated people were 11 times more likely to die from COVID-19 compared to those who were fully vaccinated, the Centers for Disease Control and Prevention reported in a new study Friday, providing more evidence of the vaccines’ effectiveness at preventing severe disease, even as protection from mild breakthrough cases appears to be waning in the face of the Delta variant.

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“Looking at cases over the past two months when the Delta variant was the predominant variant circulating in this country, those who were unvaccinated were about four and a half times more likely to get COVID-19, over 10 times more likely to be hospitalized, and 11 times more likely to die from the disease,”  CDC Director Rochelle Walensky said at a briefing Friday.

The CDC’s latest data, published as three studies Friday in the agency’s Morbidity and Mortality Weekly Report, are also the latest sign that booster shots could become necessary in the coming months for many. 

Examining the incidence of COVID-19 across 13 jurisdictions in the United States, the CDC reported that the odds of fully vaccinated people becoming sick with the virus rose as the Delta variant surged across the country.

Scientists expected fully vaccinated people to make up some 10% of cases from late June through July, if the shots retained peak effectiveness at preventing any infection. Instead, vaccinated persons accounted for 18% of observed cases — a finding the study’s authors said “were consistent with a potential decline in vaccine protection against confirmed SARS-CoV-2 infection.”

However, while protection against hospitalization and death remained relatively high in the study through mid-July, the CDC also published new data showing further evidence of waning protection against severe disease in the oldest Americans.

In data collected from the agency’s “VISION Network” cohort of hundreds of hospitals and urgent care clinics, the agency reported that vaccine effectiveness against hospitalization in adults 75 and older “was significantly lower” than in younger patients through August. A handful of Veterans Affairs Medical Centers reached a similar conclusion in their data, estimating effectiveness against hospitalization for adults 65 and older at 80%.

Both studies reported that their findings of declining effectiveness against hospitalization had not been previously observed in their cohorts.

The CDC has previously reported vaccine effectiveness against hospitalization appearing to drop over time in other cohorts, though still remaining above 80% through July. 

The new results come as federal health officials say they are moving ahead with plans to roll out booster shots nationwide, pending approval from the Food and Drug Administration and formal recommendations from a panel of the CDC’s expert vaccine advisers.

Pfizer is expected to be first to win approval from the FDA for a booster shot. The regulator plans to convene its panel of vaccine experts to deliberate over the company’s booster shot data next week, ahead of the administration’s planned rollout the week of September 20th.

Federal health officials say they also hope to allow for booster shots for recipients of Moderna and Johnson & Johnson’s vaccines in the coming weeks, pending more data from the drugmakers.

The Biden administration has also pointed to data collected abroad to underscore the need to roll out additional doses of the vaccine for those most at-risk; Israel, for example, has already begun administering booster shots.

“Israel has been a very interesting phenomenon to observe, because they seem to be ahead, certainly of the United States, in every element of the outbreak, including response to vaccines,” Dr. Anthony Fauci, the president’s chief medical adviser, told a virtual event hosted by the London School of Hygiene and Tropical Medicine on Wednesday.

Yale University researchers, in a federally-funded preprint study that has yet to be peer-reviewed, recently reported the early booster shot rollout there appeared to reduce the odds of infection by up to 68%.

Israeli health officials have also briefed the Biden administration on additional unpublished data from their booster program. The country’s prime minister recently urged President Biden to speed the U.S. booster strategy, which currently plans for Americans to get their additional shots 8 months after completing their initial regimen.

“Although earlier studies showed that hospitalization protection, most recent studies, in my personal communication with Israeli health authorities, indicate that there’s even now a significant diminution,” added Fauci.

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Measles case reported locally turns out to be negative: health unit

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NEWS RELEASE
SIMCOE MUSKOKA DISTRICT HEALTH UNIT
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On March 26, the Simcoe Muskoka District Health Unit (SMDHU) was notified by Public Health Ontario’s (PHO) laboratory that due to laboratory error, the case of measles that had been lab-confirmed positive on March 12, based on symptoms and a positive urine measles laboratory result by PHO’s laboratory, is in fact negative for the measles virus.

“With this new information of the negative lab result, we believe that that individual was not infected with measles and that there has not been any public exposure to measles resulting from this individual’s illness,” said Dr. Charles Gardner, medical officer of health. “We recognize that notifying the public of what we believed to be a positive measles case in our area created worry, anxiety and disruption for some, and we regret this.

“We do know that, despite best efforts, on rare occasions laboratory errors can occur. We are working closely with the PHO’s laboratory to do all that we can to ensure that such an incident does not occur again.”

Measles is a highly contagious viral infection that spreads very easily through airborne transmission. The measles virus can live in the air or on surfaces for up to two hours.

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Symptoms of measles begin seven to 21 days after exposure and include fever, runny nose, cough, drowsiness, and red eyes. Small white spots appear on the inside of the mouth and throat but are not always present. Three to seven days after symptoms begin, a red, blotchy rash appears on the face and then progresses down the body.

The risk of transmission to those vaccinated with two doses is low, and when it does occur tends to show a reduction in the severity of these symptoms.

“Although we are relieved for the individual involved, and for all Simcoe-Muskoka residents, that this case has now been confirmed as negative, we know that measles is still active in Ontario at this time and the potential remains for new cases to arise, especially given the increase in Ontarians travelling to areas in the world that have higher numbers of measles cases,” said Dr. Gardner. “This is why we continue to advise individuals to keep up to date with their routine immunizations, including measles, mumps and rubella (MMR) vaccination.”

The risk of measles is low for people who have been fully immunized with two doses of measles vaccine or those born before 1970; however, many children have been delayed in receiving their routine childhood immunizations and people who have not had two doses of measles vaccine are at higher risk of contracting the disease.

People who do get sick usually recover without treatment, but measles can be more severe for infants, pregnant women, and those with compromised immune systems. Possible complications include middle-ear infections, pneumonia, diarrhea, or encephalitis (swelling of the brain) and occasionally death in the very young. Even individuals who are up to date with the measles vaccine should watch for symptoms of measles for 21 days after exposure.

For more information about measles, please visit smdhu.org or call Health Connection at 705-721-7520 or 1-877-721-7520, Monday to Friday between 8:30 a.m. and 4:30 p.m. to speak with a public health professional.

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Kate Middleton Not Alone. Cancer On Rise For People Under 50, Say Experts

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Kate Middleton revealed on Friday that her cancer was discovered after she received abdominal surgery

London:

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When Catherine, Princess of Wales, revealed she was being treated for cancer last week, part of the shock was that an otherwise healthy 42-year-old has a disease that mostly plagues older people.

However, researchers have been increasingly sounding the alarm that more and more people under 50 are getting cancer — and no one knows why.

Across the world, the rate of under-50s diagnosed with 29 common cancers surged by nearly 80 percent between 1990 and 2019, a large study in BMJ Oncology found last year.

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The researchers predicted the number of new cancer cases among younger adults will rise another 30 percent by the end of this decade, with wealthy countries particularly affected.

The increase in cases — and soaring global population — means that the number of deaths among under 50s from cancer has risen by nearly 28 percent over the last 30 years.

This occurred even as the odds of people of all ages surviving cancer have roughly doubled over the last half century.

Shivan Sivakumar, a cancer researcher at the UK’s University of Birmingham, called it an “epidemic” of young adult cancer.

Since Kate Middleton revealed on Friday that her cancer was discovered after she received abdominal surgery earlier this year, Sivakumar and other doctors have spoken out about the uptick in younger cancer patients they have been seeing at their clinics.

While breast cancer remains the most common for people under 50, the researchers expressed particular concern about the rise of gastrointestinal cancers — such as of the colon, pancreas, liver and oesophagus — in younger adults.

Colon cancer is now the leading cause of cancer deaths in men under 50 in the United States, according to the American Cancer Society. For women, it is number two — behind only breast cancer.

One high profile case of colorectal cancer was “Black Panther” actor Chadwick Boseman, who died at the age of 43 in 2020.

Why is this happening?

“We just don’t have the evidence yet” to say exactly what is causing this rise, Sivakumar told AFP, adding it was likely a combination of factors.

Helen Coleman, a cancer epidemiology professor at Queen’s University Belfast who has studied early onset cancer in Northern Ireland, told AFP there were two potential explanations.

One is that people in their 40s were exposed to factors known to cause cancer — such tobacco smoke, alcohol or being obese — at an earlier age than previous generations.

She pointed out that the “obesity epidemic” did not start until the 1980s.

Sivakumar felt that at least part of the puzzle could be explained by obesity.

However, there is “another wave” of under-50 patients who are neither obese nor genetically predisposed still getting cancer, he emphasised, adding that this could not be put down to “statistical chance”.

The other theory, Coleman said, is that “something different” has been going on with her generation.

Fingers have been pointed out a range of possible culprits — including chemicals, new drugs and microplastics — but none have been proven.

Some have suggested that so-called ultra-processed foods could be to blame. “But there’s very little data to back any of that up,” Coleman said.

Another theory is that the food we eat could be changing our gut microbiome.

While there is nothing conclusive yet, Coleman said her own research suggested that cancer causes changes to the microbiome, not the other way around.

Anti-vaxx conspiracy theorists have even tried to blame Covid-19 vaccines.

This is easily disproven, because the rise in young adult cancer has taken place over decades, but the vaccines have only been around for a few years.

What can be done?

To address the rise in younger colorectal cancer, in 2021 the US lowered the recommended age for screening to 45. Other countries have yet to follow suit.

But the researchers hoped that Catherine’s experience would remind people at home that they should consult their doctor if they sense anything is wrong.

“People know their bodies really well,” Sivakumar said.

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“If you really feel that something isn’t right, don’t delay — just get yourself checked out.”

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Almost 3,000 students suspended in Waterloo Region over immunization issues

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Close to 3,000 children attending elementary school across Waterloo Region were suspended from school on Wednesday morning for not having up-to-date immunization records.

The region says Waterloo Public Health suspended 2,969 students under the Immunization of School Pupils Act (ISPA).

For several months, the region has been campaigning for people to get their children’s vaccinations up to date, including sending letters home to parents on a couple of occasions, warning that students’ records needed to be up to date or they would be suspended.

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It announced in January that 32,000 students did not have up-to-date records: 22,000 elementary students and 10,000 high school students.


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“We have made remarkable progress from the original 27,567 immunization notices we sent to parents in November and December 2023,” Dr. Hsiu-Li Wang, medical officer of health, stated.

“Since that time, we have resolved more than 24,500 outdated vaccination records, providing students with valuable protection against these serious and preventable diseases.”

The high school students still have a few weeks to get their records up to date or else face suspension.

The ISPA requires students to have proof-of-vaccination records for diphtheria, polio, tetanus, pertussis, measles, mumps, rubella, varicella (chickenpox) and meningitis, which must be on file with public health.

Public health says caregivers whose children are suspended will need to book an appointment at regionofwaterloo.ca/vaccines for clinics, which will be held in Cambridge and Waterloo on weekdays.

“Given the high number of suspensions, it may take several days before you can be seen at an appointment and return your child to school,” a release from the region warns.

“Record submission and questions must be done in person to ensure immediate resolution.”

The last time suspensions over immunizations were issued was in 2019, when 1,032 students were suspended.

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