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1 in 5 deaths globally are due to sepsis, study says — many more than previously estimated – CNN

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The study, published Thursday in the journal the Lancet, found that sepsis has killed fewer people over the last couple decades, but still accounts for 1 in 5 deaths globally.
Florida man has 25% of his skin stripped from his body in his fight against flesh-eating bacteria
The study estimates that in 2017 there were 48.9 million cases of sepsis worldwide and 11 million deaths. That means 19.7% of all deaths globally were sepsis-related. Previous global estimates were significantly lower.
When someone has sepsis, their body essentially overreacts to an infection. This out-of-control immune responses can cause organs to shut down. Deaths from sepsis in 2017 peaked in early childhood, declined in early adulthood and rose again among the elderly.
In 2017, an estimated 20.3 million sepsis cases and 2.9 million deaths worldwide were among children younger than 5 years old. Many were newborns.
Researchers came to these higher numbers looking at more than 109 million individual death records and trends from 1990 through 2017. The data came from the Global Burden of Disease study, which reports on 282 primary causes of deaths in 196 countries and territories.
The researchers used records of people who were hospitalized with sepsis and people with sepsis who were not treated in a hospital. Earlier studies focused on hospital records only, and most past studies did not capture the global scope of the issue.
Man dies after being licked by his dog and contracting rare infectionMan dies after being licked by his dog and contracting rare infection
This new study found that the number of sepsis cases fell 37% and deaths fell more than 52% since 1990, but was still a significant problem in parts of the world such as sub-Saharan Africa, South and East Asia and Oceania.
From 1990 until 2017, the most common underlying cause of sepsis was diarrheal disease, and the the most common underlying cause of sepsis-related deaths was lower respiratory infections. The most common injury that started sepsis was an injury from a car accident. Maternal disorders such as postpartum infections were the most common non-communicable disease that resulted in sepsis. Antimicrobial resistance was also noted as an important driver of sepsis, particularly in hospitals and clinics.
“We are alarmed to find sepsis deaths are much higher than previously estimated, especially as the condition is both preventable and treatable,” author Dr. Mohsen Naghavi, a professor of health metrics sciences at the Institute for Health Metrics and Evaluation at the University of Washington School of Medicine, said in a press release. “We need renewed focus on sepsis prevention among newborns and on tackling antimicrobial resistance, an important driver of the condition.”

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COVID-19 immunization clinics open to B.C. kids ages five to 11 today – Toronto Star

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VICTORIA – Children in British Columbia between five and 11 years old can start getting shots of a pediatric COVID-19 vaccine today.

Provincial health officer Dr. Bonnie Henry said last week that about 350,000 children are eligible to receive the modified dose of the Health Canada-approved Pfizer-BioNTech vaccine.

Health Canada approved the pediatric shot for use in Canada after an independent scientific review confirmed the first vaccine formulated for younger children is safe and effective.

Henry says the same vaccine has been administered to more than three million children in the United States and there have been no “safety signals” as a result.

She says the vaccine will help children and families safely return to activities that benefit physical and mental health.

Dr. Penny Ballem, the executive lead for B.C.’s vaccination drive, has said she expects the full children’s immunization effort including second doses to conclude by the end of January.

This report by The Canadian Press was first published Nov. 29, 2021.

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COVID-19 immunization clinics open to B.C. kids ages five to 11 today – Times Colonist

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VICTORIA — Children in British Columbia between five and 11 years old can start getting shots of a pediatric COVID-19 vaccine today. 

Provincial health officer Dr. Bonnie Henry said last week that about 350,000 children are eligible to receive the modified dose of the Health Canada-approved Pfizer-BioNTech vaccine.

Health Canada approved the pediatric shot for use in Canada after an independent scientific review confirmed the first vaccine formulated for younger children is safe and effective. 

Henry says the same vaccine has been administered to more than three million children in the United States and there have been no “safety signals” as a result.

She says the vaccine will help children and families safely return to activities that benefit physical and mental health.

Dr. Penny Ballem, the executive lead for B.C.’s vaccination drive, has said she expects the full children’s immunization effort including second doses to conclude by the end of January.

This report by The Canadian Press was first published Nov. 29, 2021.

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COVID-19: Children between five and 11 are eligible for vaccinations starting Monday – Vancouver Sun

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Health Canada approved the Pfizer vaccine for children aged five to 11 on Nov. 19. This vaccine uses a lower dose of 10 micrograms — one-third of the dose given to older children and adults

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Children in B.C. between five and 11 years old start receiving the first doses of their COVID-19 vaccines on Monday.

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More than 90,000 out of the 350,000 eligible children, or 26 per cent, in that age category were registered a week before the rollout, according to the B.C. government.

The government’s own surveys show that most parents support getting vaccines for their young children, but there are some whose views might keep the vaccination rate lower for this age category.

Of B.C. parents who responded, 58 per cent will register to vaccinate their children right away, while another 18 per cent planned to wait, and nearly 25 per cent said they are not sure they will do it, according to Penny Ballem, the executive lead for B.C.’s immunization efforts.

A parent or legal guardian has to give verbal consent ahead of a child being vaccinated, according to Ballem.

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Health Canada approved the Pfizer vaccine for children aged five to 11 on Nov. 19. This vaccine uses a lower dose of 10 micrograms that is one-third of the dose given to older children and adults.

COVID-19 information from the B.C. Centre for Disease Control from Nov. 25 shows that 80 per cent of British Columbians at the next age group up, aged 12 to 17, are now fully vaccinated and more than 87 per cent have a first dose.

There are varying rates in different health authorities, however. In Fraser, Vancouver Coastal and Vancouver Island, it is higher at 82 per cent, 89 per cent and 83 per cent, respectively. In Interior, it was 70 per cent and in Northern, it was 59 per cent.

Within authorities, there is also a wide spectrum. As of Nov. 23, Enderby and Kettle Creek in the Interior authority had only 38 per cent of 12- to 17-year-olds double vaccinated, while Kimberley posted 80 per cent. In Vancouver Coastal, Bella Coola Valley had 59 per cent of 12- to 17-year-olds double vaccinated, while North Vancouver was at 93 per cent.

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Between Oct. 27 to Nov. 25, the number of average daily cases per 100,000 people among the double vaccinated for this 12 to 17 age group across B.C. was 2.5. Among those who had one vaccination, the number of average daily cases per 100,000 people was 8.2. And for the unvaccinated, the figure was 46.8 per 100,000.

For that same period, in the category of 0-11 year olds, who are all unvaccinated, the number of average daily cases per 100,000 people was 16.8.

“I think the most important thing is that vaccinations be readily available for all children and families,” said Teri Mooring, president of the B.C. Teachers’ Federation.

“For families where it’s not convenient for them to book an appointment in a separate clinic or perhaps they work long hours or there are other various individual circumstances, we think there should be an option (for COVID-19 vaccination) in schools as well.”

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Mooring said that “it was a concern with the 12- to 17-year-olds as well and what we’re seeing in some parts of the province, where we have vaccine hesitancy, we are still those (vaccination) numbers lag behind. We don’t want that to be the case for the five to 11-year-olds.”

Youth aged 12 to 18 have to carry a B.C. Vaccine card, or have a trusted adult carry one for them, to go to restaurants and attend indoor, organized events. Unlike adults, they don’t have to also show government-issued identification. Children aged five to 11 are not be required to show proof of vaccination.

jlee-young@postmedia.com

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