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Johnson & Johnson vaccine approved in Canada. How does it compare to the others? – Global News

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Canada has now approved four different coronavirus vaccines after giving the green light to Johnson & Johnson’s COVID-19 shot.

Johnson & Johnson’s single-dose shot joins a growing arsenal of vaccines that include shots from Pfizer, Moderna and AstraZeneca to protect Canadians against COVID-19.

Read more:
Canada approves Johnson & Johnson’s 1-shot COVID-19 vaccine

At this time, we consider all available vaccines to be effective,” said Dr. Supriya Sharma, Health Canada’s chief medical advisor, at a press conference on Friday.

Our advice to Canadians is to get whichever vaccine is available to you.”

Here’s a closer look at all the vaccines that Canada has approved so far:

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Johnson & Johnson

Unlike Pfizer and Moderna’s vaccines, the Johnson & Johnson shot is an adenovirus-based vaccine.

It was built using a kind of virus, which causes colds in chimpanzees.

The adenovirus is altered to carry a gene for the coronavirus protein, which can then train a person’s immune system to recognize the actual coronavirus if it ever enters the body.


Click to play video 'Coronavirus: Health officials urge people to take whichever vaccine available regardless of efficacy rate'



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Coronavirus: Health officials urge people to take whichever vaccine available regardless of efficacy rate


Coronavirus: Health officials urge people to take whichever vaccine available regardless of efficacy rate

It only requires one dose and has been approved for use in individuals aged 18 and older and is effective in older adults, Sharma said.

Almost 20 per cent of the participants in the clinical trials were 65 years of age and older, and no differences in the safety or efficacy were seen compared to the younger groups,” she said.

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Read more:
Is a single COVID-19 vaccine dose enough for those previously infected?

The shot is significantly easier to ship and store, as it can be kept in a refrigerator (between 2 C and 8 C) for at least three months — much longer than the Moderna vaccine — rather than a freezer.

In clinical trials, it showed an overall efficacy of 66 per cent in preventing moderate to severe COVID-19, Sharma said.

Canada has pre-ordered 10 million doses of the vaccine, with options to order up to 28 million more.

AstraZeneca

AstraZeneca’s two-dose shot was approved for use on Feb. 26.

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Like the Johnson & Johnson vaccine, this is also an adenovirus-based vaccine and can be stored at normal fridge temperature — meaning the doses are much easier both to ship and to keep.

The Oxford-AstraZeneca vaccine was found to be 62 per cent effective in a two-dose clinical trial.

Read more:
If AstraZeneca isn’t widely recommended for seniors, who should get the vaccine?

The protocol for giving the booster shot set and used in the clinical trials for AstraZenenca was one month after the first dose.

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The World Health Organization (WHO) has recommended that the AstraZeneca vaccine can be given with an interval of eight to 12 weeks.


Click to play video 'AstraZeneca vaccine arrives in Canada with a shelf life of less than a month'



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AstraZeneca vaccine arrives in Canada with a shelf life of less than a month


AstraZeneca vaccine arrives in Canada with a shelf life of less than a month

Health Canada has approved the shot for all adults — anyone 18 years and older.

But Canada’s National Advisory Committee on Immunization (NACI) is not currently recommending the AstraZeneca vaccine for people 65 or older “due to limited information on the efficacy of this vaccine in this age group at this time.”

The first two phases of AstraZeneca’s trials did not include people over the age of 65.

Canada has purchased 20 million doses — enough to vaccine 10 million Canadians.

Moderna

Moderna’s mRNA vaccine was the second COVID-19 shot approved for use in Canada back on Dec. 23.

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Moderna’s shot was manufactured using mRNA-based technology, a relatively new way to make vaccines.

Instead of injecting a deactivated form of the virus, the mRNA vaccine uses a component of the virus called messenger RNA that basically contains the genetic instructions for the human body to make the specific spike protein of the coronavirus.


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Questions about safety of delaying second COVID-19 vaccine dose


Questions about safety of delaying second COVID-19 vaccine dose

By doing this, the immune system learns to recognize and respond to that specific protein, meaning it can more quickly mount a response if the virus enters the body.

The two doses are supposed to be given four weeks or 28 days apart, but many provinces are now extending that time to up to four months amid shortages, as recommended by NACI.

Clinical trials found Moderna’s vaccine to be 94.1 per cent effective in preventing COVID-19.

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The Moderna doses can be stored in a freezer between -25 C and -15 C. The Moderna doses can be stored in a freezer between -25 C and -15 C. Territories have been guaranteed priority access to this particular vaccine, as it’s easier to safely transport and store compared to Pfizer’s — which was approved first.

Canada’s agreement with Moderna is for 40 million doses — although the feds have the option of purchasing another 16 million in addition to that. The 40 million doses are enough to inoculate 20 million Canadians, over half of the population.

Pfizer

On Dec. 9, Pfizer’s coronavirus vaccine became the first COVID-19 shot to get approval in the country.

Canada has 40 million Pfizer doses secured in its agreement with the manufacturer.

Like Moderna’s jab, this is also an mRNA vaccine and requires two doses — which the company recommends be given three weeks or 21 days apart, as done in clinical trials.

Pfizer’s clinical trials were only conducted on those over the age of 16, which means that until further studies are completed in younger age groups, anyone under 16 years old is ineligible for the jab.

Read more:
Provinces, territories can wait 4 months to administer 2nd COVID-19 shot, NACI says

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Of the four vaccines, Pfizer is the most demanding about temperature. This vaccine requires ultra-cold storage, meaning it has to be transported and stored at -70 C. This makes the vaccine tricky to ship to remote regions, where the appropriate infrastructure is far more difficult to set up.

On Feb. 25, Pfizer-BioNTech requested a change to allow its COVID-19 vaccine to be kept at between -25 C and -15 C instead of the earlier approved storage condition of between -80 C and -60 C.

While Health Canada still endorses ultra-cold storage conditions for the Pfizer-BioNTech vaccine, the department “after conducting a thorough review” said on Wednesday that the doses can now be stored and shipped “at standard freezer temperatures” for up to 14 days.


Click to play video 'Coronavirus: Health Canada rules Pfizer vaccine can be stored at standard temperatures'



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Coronavirus: Health Canada rules Pfizer vaccine can be stored at standard temperatures


Coronavirus: Health Canada rules Pfizer vaccine can be stored at standard temperatures

In terms of effectiveness, Pfizer takes the gold. At 95 per cent, it narrowly edges Moderna for a photo-finish.

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Still, at the end of the day, Canadians should feel confident that any one of the three approved vaccines will cut off COVID-19’s claws and protect them from the worst outcomes of the virus.

“All vaccines will help Canadians to fight the pandemic,” said Health Canada’s Dr. Marc Berthiaume at Friday’s press conference.

“The efficacy rates may vary depending on the design and studies, but we feel that overall these are very good vaccine choices.”

— with files from Global News’ Rachel Gilmore 

© 2021 Global News, a division of Corus Entertainment Inc.

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Transat AT reports $39.9M Q3 loss compared with $57.3M profit a year earlier

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MONTREAL – Travel company Transat AT Inc. reported a loss in its latest quarter compared with a profit a year earlier as its revenue edged lower.

The parent company of Air Transat says it lost $39.9 million or $1.03 per diluted share in its quarter ended July 31.

The result compared with a profit of $57.3 million or $1.49 per diluted share a year earlier.

Revenue in what was the company’s third quarter totalled $736.2 million, down from $746.3 million in the same quarter last year.

On an adjusted basis, Transat says it lost $1.10 per share in its latest quarter compared with an adjusted profit of $1.10 per share a year earlier.

Transat chief executive Annick Guérard says demand for leisure travel remains healthy, as evidenced by higher traffic, but consumers are increasingly price conscious given the current economic uncertainty.

This report by The Canadian Press was first published Sept. 12, 2024.

Companies in this story: (TSX:TRZ)

The Canadian Press. All rights reserved.

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Dollarama keeping an eye on competitors as Loblaw launches new ultra-discount chain

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Dollarama Inc.’s food aisles may have expanded far beyond sweet treats or piles of gum by the checkout counter in recent years, but its chief executive maintains his company is “not in the grocery business,” even if it’s keeping an eye on the sector.

“It’s just one small part of our store,” Neil Rossy told analysts on a Wednesday call, where he was questioned about the company’s food merchandise and rivals playing in the same space.

“We will keep an eye on all retailers — like all retailers keep an eye on us — to make sure that we’re competitive and we understand what’s out there.”

Over the last decade and as consumers have more recently sought deals, Dollarama’s food merchandise has expanded to include bread and pantry staples like cereal, rice and pasta sold at prices on par or below supermarkets.

However, the competition in the discount segment of the market Dollarama operates in intensified recently when the country’s biggest grocery chain began piloting a new ultra-discount store.

The No Name stores being tested by Loblaw Cos. Ltd. in Windsor, St. Catharines and Brockville, Ont., are billed as 20 per cent cheaper than discount retail competitors including No Frills. The grocery giant is able to offer such cost savings by relying on a smaller store footprint, fewer chilled products and a hearty range of No Name merchandise.

Though Rossy brushed off notions that his company is a supermarket challenger, grocers aren’t off his radar.

“All retailers in Canada are realistic about the fact that everyone is everyone’s competition on any given item or category,” he said.

Rossy declined to reveal how much of the chain’s sales would overlap with Loblaw or the food category, arguing the vast variety of items Dollarama sells is its strength rather than its grocery products alone.

“What makes Dollarama Dollarama is a very wide assortment of different departments that somewhat represent the old five-and-dime local convenience store,” he said.

The breadth of Dollarama’s offerings helped carry the company to a second-quarter profit of $285.9 million, up from $245.8 million in the same quarter last year as its sales rose 7.4 per cent.

The retailer said Wednesday the profit amounted to $1.02 per diluted share for the 13-week period ended July 28, up from 86 cents per diluted share a year earlier.

The period the quarter covers includes the start of summer, when Rossy said the weather was “terrible.”

“The weather got slightly better towards the end of the summer and our sales certainly increased, but not enough to make up for the season’s horrible start,” he said.

Sales totalled $1.56 billion for the quarter, up from $1.46 billion in the same quarter last year.

Comparable store sales, a key metric for retailers, increased 4.7 per cent, while the average transaction was down2.2 per cent and traffic was up seven per cent, RBC analyst Irene Nattel pointed out.

She told investors in a note that the numbers reflect “solid demand as cautious consumers focus on core consumables and everyday essentials.”

Analysts have attributed such behaviour to interest rates that have been slow to drop and high prices of key consumer goods, which are weighing on household budgets.

To cope, many Canadians have spent more time seeking deals, trading down to more affordable brands and forgoing small luxuries they would treat themselves to in better economic times.

“When people feel squeezed, they tend to shy away from discretionary, focus on the basics,” Rossy said. “When people are feeling good about their wallet, they tend to be more lax about the basics and more willing to spend on discretionary.”

The current economic situation has drawn in not just the average Canadian looking to save a buck or two, but also wealthier consumers.

“When the entire economy is feeling slightly squeezed, we get more consumers who might not have to or want to shop at a Dollarama generally or who enjoy shopping at a Dollarama but have the luxury of not having to worry about the price in some other store that they happen to be standing in that has those goods,” Rossy said.

“Well, when times are tougher, they’ll consider the extra five minutes to go to the store next door.”

This report by The Canadian Press was first published Sept. 11, 2024.

Companies in this story: (TSX:DOL)

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U.S. regulator fines TD Bank US$28M for faulty consumer reports

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TORONTO – The U.S. Consumer Financial Protection Bureau has ordered TD Bank Group to pay US$28 million for repeatedly sharing inaccurate, negative information about its customers to consumer reporting companies.

The agency says TD has to pay US$7.76 million in total to tens of thousands of victims of its illegal actions, along with a US$20 million civil penalty.

It says TD shared information that contained systemic errors about credit card and bank deposit accounts to consumer reporting companies, which can include credit reports as well as screening reports for tenants and employees and other background checks.

CFPB director Rohit Chopra says in a statement that TD threatened the consumer reports of customers with fraudulent information then “barely lifted a finger to fix it,” and that regulators will need to “focus major attention” on TD Bank to change its course.

TD says in a statement it self-identified these issues and proactively worked to improve its practices, and that it is committed to delivering on its responsibilities to its customers.

The bank also faces scrutiny in the U.S. over its anti-money laundering program where it expects to pay more than US$3 billion in monetary penalties to resolve.

This report by The Canadian Press was first published Sept. 11, 2024.

Companies in this story: (TSX:TD)

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