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COVID-19 shots for school? What needs to happen to get kids in Canada immunized

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Parents and children wanting to know when COVID-19 vaccines could roll out to Canada’s youngest people recently got a glimpse at the answers.

Dr. Supriya Sharma, Health Canada’s chief medical adviser, said it is “likely that Pfizer, if all the data is fine, may be the first” vaccine that children and teens could receive.

Pfizer and BioNTech said in a media release on Wednesday that their COVID-19 vaccine, BNT162b2, is safe with “demonstrated 100 per cent efficacy” in preventing the disease in teens aged 12 to 15.

The data hasn’t been peer reviewed or scrutinized by regulators like the U.S. Food and Drug Administration and Health Canada.

In the trial of 2,260 adolescents, there were 18 cases of COVID-19 in the group that got a placebo shot and none among those who received the vaccine.

Side-effects were similar to those reported in clinical trials in adults, such as pain at the injection site, headaches, fever and fatigue.

 

Pfizer-BioNTech says its vaccine is safe and showed 100 per cent efficacy in a clinical trial of 12- to 15-year-olds. Health officials say more data is needed, but parents are optimistic about the results. 2:03

Sharma said Health Canada will review Pfizer-BioNTech’s COVID-19 vaccine data on younger teens “in a couple of weeks.” Full data, including on children aged six to 12, is expected in months.

Any approvals will only come after the regulator checks the data for safety, efficacy and quality.

Pfizer’s vaccine has been cleared for people as young as 16 in Canada.

Dr. Noni MacDonald, a pediatric infectious diseases specialist at Dalhousie University in Halifax who researches vaccine safety, said Pfizer’s research is a “bridging study.”

In a bridging study, researchers check if antibody and cell-based immune responses are equivalent to what’s seen in adults. For Pfizer, they were.

“The results are really very encouraging,” MacDonald said.

Protection for all Canadians

Moderna is also conducting a clinical trial in Canada for children aged five to 11. The results are expected early in 2022. The company also launched a trial in those aged six months to less than 12 in the U.S. in March.

Johnson & Johnson, which recently won approval for its vaccine in adults in Canada and the U.S., expanded its Phase 2 trial for those aged 12 to 17 and plans to include younger children.

AstraZeneca launched in similar trial in February.

But it’s only when vaccines roll out in the real world to children with diabetes, heart disease and other underlying conditions that answers on effectiveness will be clearer.

“We want to protect everybody in our community, even those who cannot be immunized or will not respond to the vaccine,” MacDonald said. “To do that, we need children, we need teenagers, we need young adults, we need middle-aged adults and we need older people.”

Alyson Kelvin, an assistant professor at Dalhousie working on COVID-19 vaccines at the VIDO lab in Saskatoon, said she’s excited about how the vaccines could help children return to school and sports.

“Children can be infected with the virus and pass on the virus,” Kelvin said. “Even though we might not see clinical disease in kids or the clinical disease might not be as severe as in adults, it’s really important that children are not able to be part of the transmission chain.”

MacDonald hopes vaccines could be ready for younger teens by September, in time for mass immunization programs in school.

Source:- CBC.ca

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Japan’s SoftBank returns to profit after gains at Vision Fund and other investments

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TOKYO (AP) — Japanese technology group SoftBank swung back to profitability in the July-September quarter, boosted by positive results in its Vision Fund investments.

Tokyo-based SoftBank Group Corp. reported Tuesday a fiscal second quarter profit of nearly 1.18 trillion yen ($7.7 billion), compared with a 931 billion yen loss in the year-earlier period.

Quarterly sales edged up about 6% to nearly 1.77 trillion yen ($11.5 billion).

SoftBank credited income from royalties and licensing related to its holdings in Arm, a computer chip-designing company, whose business spans smartphones, data centers, networking equipment, automotive, consumer electronic devices, and AI applications.

The results were also helped by the absence of losses related to SoftBank’s investment in office-space sharing venture WeWork, which hit the previous fiscal year.

WeWork, which filed for Chapter 11 bankruptcy protection in 2023, emerged from Chapter 11 in June.

SoftBank has benefitted in recent months from rising share prices in some investment, such as U.S.-based e-commerce company Coupang, Chinese mobility provider DiDi Global and Bytedance, the Chinese developer of TikTok.

SoftBank’s financial results tend to swing wildly, partly because of its sprawling investment portfolio that includes search engine Yahoo, Chinese retailer Alibaba, and artificial intelligence company Nvidia.

SoftBank makes investments in a variety of companies that it groups together in a series of Vision Funds.

The company’s founder, Masayoshi Son, is a pioneer in technology investment in Japan. SoftBank Group does not give earnings forecasts.

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Yuri Kageyama is on X:

The Canadian Press. All rights reserved.

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Trump campaign promises unlikely to harm entrepreneurship: Shopify CFO

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Shopify Inc. executives brushed off concerns that incoming U.S. President Donald Trump will be a major detriment to many of the company’s merchants.

“There’s nothing in what we’ve heard from Trump, nor would there have been anything from (Democratic candidate) Kamala (Harris), which we think impacts the overall state of new business formation and entrepreneurship,” Shopify’s chief financial officer Jeff Hoffmeister told analysts on a call Tuesday.

“We still feel really good about all the merchants out there, all the entrepreneurs that want to start new businesses and that’s obviously not going to change with the administration.”

Hoffmeister’s comments come a week after Trump, a Republican businessman, trounced Harris in an election that will soon return him to the Oval Office.

On the campaign trail, he threatened to impose tariffs of 60 per cent on imports from China and roughly 10 per cent to 20 per cent on goods from all other countries.

If the president-elect makes good on the promise, many worry the cost of operating will soar for companies, including customers of Shopify, which sells e-commerce software to small businesses but also brands as big as Kylie Cosmetics and Victoria’s Secret.

These merchants may feel they have no choice but to pass on the increases to customers, perhaps sparking more inflation.

If Trump’s tariffs do come to fruition, Shopify’s president Harley Finkelstein pointed out China is “not a huge area” for Shopify.

However, “we can’t anticipate what every presidential administration is going to do,” he cautioned.

He likened the uncertainty facing the business community to the COVID-19 pandemic where Shopify had to help companies migrate online.

“Our job is no matter what comes the way of our merchants, we provide them with tools and service and support for them to navigate it really well,” he said.

Finkelstein was questioned about the forthcoming U.S. leadership change on a call meant to delve into Shopify’s latest earnings, which sent shares soaring 27 per cent to $158.63 shortly after Tuesday’s market open.

The Ottawa-based company, which keeps its books in U.S. dollars, reported US$828 million in net income for its third quarter, up from US$718 million in the same quarter last year, as its revenue rose 26 per cent.

Revenue for the period ended Sept. 30 totalled US$2.16 billion, up from US$1.71 billion a year earlier.

Subscription solutions revenue reached US$610 million, up from US$486 million in the same quarter last year.

Merchant solutions revenue amounted to US$1.55 billion, up from US$1.23 billion.

Shopify’s net income excluding the impact of equity investments totalled US$344 million for the quarter, up from US$173 million in the same quarter last year.

Daniel Chan, a TD Cowen analyst, said the results show Shopify has a leadership position in the e-commerce world and “a continued ability to gain market share.”

In its outlook for its fourth quarter of 2024, the company said it expects revenue to grow at a mid-to-high-twenties percentage rate on a year-over-year basis.

“Q4 guidance suggests Shopify will finish the year strong, with better-than-expected revenue growth and operating margin,” Chan pointed out in a note to investors.

This report by The Canadian Press was first published Nov. 12, 2024.

Companies in this story: (TSX:SHOP)

The Canadian Press. All rights reserved.

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RioCan cuts nearly 10 per cent staff in efficiency push as condo market slows

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TORONTO – RioCan Real Estate Investment Trust says it has cut almost 10 per cent of its staff as it deals with a slowdown in the condo market and overall pushes for greater efficiency.

The company says the cuts, which amount to around 60 employees based on its last annual filing, will mean about $9 million in restructuring charges and should translate to about $8 million in annualized cash savings.

The job cuts come as RioCan and others scale back condo development plans as the market softens, but chief executive Jonathan Gitlin says the reductions were from a companywide efficiency effort.

RioCan says it doesn’t plan to start any new construction of mixed-use properties this year and well into 2025 as it adjusts to the shifting market demand.

The company reported a net income of $96.9 million in the third quarter, up from a loss of $73.5 million last year, as it saw a $159 million boost from a favourable change in the fair value of investment properties.

RioCan reported what it says is a record-breaking 97.8 per cent occupancy rate in the quarter including retail committed occupancy of 98.6 per cent.

This report by The Canadian Press was first published Nov. 12, 2024.

Companies in this story: (TSX:REI.UN)

The Canadian Press. All rights reserved.

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