This is an excerpt from Second Opinion, a weekly roundup of health and medical science news emailed to subscribers every Saturday morning. If you haven’t subscribed yet, you can do that by clicking here.
Omicron is ramping up the push for widespread boosters in Canada, shifting the conversation away from providing added protection to the most vulnerable and toward giving everyone eligible an additional shot to stave off potential spread of the highly transmissible variant.
Canada has seen dozens of omicron cases emerge in the two weeks since the variant was first identified, and new data from around the world has public health officials on high alert for signs of wider spread here.
But while there is growing concern about the threat of omicron as we learn more about it in real time, there are also early, hopeful signs that it may not cause as severe illness as previous variants and that boosters may be effective at slowing its spread.
A new report from the U.S. Centers for Disease Control and Prevention found that out of the 43 omicron cases identified in 22 states in early December, just one person needed a brief hospital stay, and there were no reported deaths from the variant.
WATCH | Omicron spreading faster than delta but may be milder, early data suggests:
Omicron more transmissible but milder than delta variant, initial research suggests
4 days ago
Duration 1:59
Initial evidence about the omicron variant seems to suggest that the strain is more transmissible but less severe than the delta variant. But scientists studying omicron caution that understanding the full threat of omicron will take more time. 1:59
“We are seeing fewer symptoms so far with omicron, and it almost certainly has a lot to do with the fact that people have some degree of immunity,” said Deepta Bhattacharya, an immunologist at the University of Arizona.
“But I don’t think there’s any doubt that omicron has more immune-evasive properties than delta … so you can imagine that omicron would have more of an advantage spreading in places where people already have some immunity than with delta.”
South Africa reported a near-record high in daily infections this week, but scientists have not yet seen evidence that omicron is causing more serious illness, which could either be a sign of things to come or a delay in the true impact it will have there.
“The severity does not look very high, which is good, but the infected population is skewing young and so would be expected to have milder infections,” said Bill Hanage, an epidemiologist at the Harvard T.H. Chan School of Public Health in Boston.
A shopper passes graffiti on a wall in London on Dec. 3. New measures to combat the new omicron COVID-19 variant came into force in the U.K. on Tuesday, with face coverings again mandatory in shops and on public transport. (Kirsty Wigglesworth/The Associated Press)
Yet the report also found booster shots provided an estimated 70 to 75 per cent protection against mild disease from omicron, giving the first real-world glimpse at the benefit offered by third doses in the face of the fast-spreading variant.
“While the data isn’t perfect, and of course there’s still a lot of questions that remain, all the arrows are pointing in the direction that two doses of a vaccine will still be very helpful — but three doses of a vaccine will be better,” said Dr. Isaac Bogoch, an infectious diseases physician and member of Ontario’s COVID-19 vaccine task force.
“There should be a sense of urgency to roll out third doses, especially now as we have a holiday season upon us and we’re going to have a growing number of omicron cases in the country.”
Omicron spreading rapidly in Canada
The Public Health Agency of Canada (PHAC) released new modelling data Friday showing COVID-19 levels could spike in the coming weeks amid an ongoing wave of delta infections and the growing threat of omicron as the holidays rapidly approach.
In Quebec, officials are investigating two potential omicron exposures at a gym and community centre in Montreal — with 14 cases of the variant detected in the city so far — but have said there is no evidence yet of wider community transmission.
British Columbia announced plans to expand its booster-shot program this week as officials reported several new cases of omicron, while Saskatchewan recently expanded shots to those 50 and over, as four omicron cases emerged there.
But as new data pours in from Canada and globally on omicron’s ability to rapidly transmit and partially evade immunity from vaccination and prior infections, early signals hint that vaccines will still provide significant protection from hospitalization and death.
WATCH | Pfizer says booster shots effective against omicron variant in early findings:
Pfizer says 3 shots neutralize omicron variant in early findings
3 days ago
Duration 2:30
Pfizer-BioNTech have reported early findings that show three doses of their COVID-19 vaccine are more effective than two when it comes to neutralizing the omicron variant in lab settings. The World Health Organization cautioned against jumping to conclusions, saying the unvaccinated should get their first doses before worrying about third shots. 2:30
But what gained far less attention was the fact that two doses of the vaccine still offered strong protection against severe COVID-19, meaning a surge in omicron cases in highly vaccinated countries, like Canada, may not lead to an overwhelmed health-care system.
“The fact that the two-dose regimen of Pfizer holds up against what really counts — serious disease — that’s really good news,” said Dr. Amesh Adalja, an infectious disease physician and a senior scholar at the Johns Hopkins Center for Health Security in Baltimore.
“People have gotten very focused on cases and preventing all infections, but I think it’s really important to prevent severe infections.”
Pfizer’s early data analyzed the blood of vaccinated individuals against omicron and found a 40-fold decrease in the level of neutralizing antibodies, which prevent the virus from entering cells. A third dose increased them by a factor of 25.
“When you hear about a 40-fold drop in neutralizing antibodies, that doesn’t mean a 40-fold drop in how well the vaccines are going to work — I would be shocked if that were the case,” said Bhattacharya.
“So will two doses, in all likelihood, substantially reduce the likelihood you will get really sick? Yes. But is there room for improvement? Yes, definitely.”
‘Rapid pivot’ to widespread boosters needed
The National Advisory Committee on Immunization (NACI) strongly recommended earlier this month that all Canadians over 50 get a booster, while those aged 18 to 49 can be offered one six months out from their second shot.
But while most provinces and territories have expanded the rollout of boosters to more age groups, only a handful have gone below the age of 50 — including Manitoba, the Northwest Territories, Yukon and soon, Ontario.
“A rapid pivot is needed in the context of growing omicron cases in the country and what we’re seeing all the data point to from around the world,” said Bogoch. “We need to roll out third doses faster.”
Canada has an opportunity to get “two steps ahead” of an omicron-driven surge by expanding boosters to all Canadians over 18 who are six months out from their second dose, Bogoch said, which would help “blunt the size of another wave.”
“How bad is it going to be here? I think we should be prepared for another wave — an omicron-driven wave of infection,” said Anne-Claude Gingras, a professor of molecular genetics at the University of Toronto.
“I have no idea if that’s going to be a wave of hospitalization and an increase in the death rate as well — but at least in terms of spread, I think if we let it in, it will.”
A patient receives a dose of the Pfizer COVID-19 vaccine at a vaccination centre in London on Dec. 4. The U.K. says it will offer all adults a booster dose of vaccine within two months, to bolster the nation’s immunity as omicron spreads. (Alberto Pezzali/The Associated Press)
Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine and co-director of the Texas Children’s Hospital Center for Vaccine Development, says we’ll no doubt see a rise in omicron cases that could be made worse by delta.
“I think, at least for a while, we will have sort of a twin epidemic of delta and omicron,” he said. “But whether you’re worried about delta or omicron — the approach you take is the same.”
Getting a booster when it’s available to you, not relying on previous COVID-19 infection for protection and getting kids vaccinated will help protect people from the spread of omicron, he said, in addition to masking, increasing ventilation and limiting gatherings.
But experts agree boosters alone won’t spare Canada from the threat of omicron — even if they will likely have some added benefit to stopping spread.
“If you boosted everybody that needed to be boosted, it wouldn’t change the trajectory of the pandemic,” said Adalja. “It’s first and second doses that change the trajectory of the pandemic.”
More than 20 per cent of eligible Canadians still aren’t doubly vaccinated — and that number sits at closer to 40 per cent in the U.S., meaning large swaths of the population remain unprotected if omicron does take off.
“We’re not going to boost our way out of the pandemic,” said Bogoch. “But if you can blunt transmission with a third dose, you’d be doing something very helpful.”
WASHINGTON (AP) — An Alaska man accused of sending graphic threats to injure and kill six Supreme Court justices and some of their family members has been indicted on federal charges, authorities said Thursday.
Panos Anastasiou, 76, is accused of sending more than 465 messages through a public court website, including graphic threats of assassination and torture coupled with racist and homophobic rhetoric.
The indictment does not specify which justices Anastasiou targeted, but Attorney General Merrick Garland said he made the graphic threats as retaliation for decisions he disagreed with.
“Our democracy depends on the ability of public officials to do their jobs without fearing for their lives or the safety of their families,” he said.
Anastasiou has been indicted on 22 counts, including nine counts of making threats against a federal judge and 13 counts of making threats in interstate commerce.
He was released from detention late Thursday by a federal magistrate in Anchorage with a a list of conditions, including that he not directly or indirectly contact any of the six Supreme Court justices he allegedly threatened or any of their family members.
During the hearing that lasted more than hour, Magistrate Kyle Reardon noted some of the messages Anastasiou allegedly sent between March 2023 and mid-July 2024, including calling for the assassination of two of the Republican-appointed Supreme Court justices so the current Democratic president could appoint their successors.
Instead of toning down his rhetoric after receiving a visit from FBI agents last year, Anastasiou increased the frequency of his messages and their vitriolic language, Reardon said.
Gray-haired and shackled at the ankles above his salmon-colored plastic slippers, Anastasiou wore a yellow prison outfit with ACC printed in black on the back, the initials for the Anchorage Correctional Facility, at the hearing. Born in Greece, he moved to Anchorage 67 years ago. Reardon allowed him to contact his elected officials on other matters like global warming, but said the messages must be reviewed by his lawyers.
Defense attorney Jane Imholte noted Anastasiou is a Vietnam veteran who is undergoing treatment for throat cancer and has no financial means other than his Social Security benefits.
She told the judge that Anastaiou, who signed his own name to the emails, worried about his pets while being detained. She said he only wanted to return home to care for his dogs, Freddie, Buddy and Cutie Pie.
He faces a maximum of 10 years in prison for each count of making threats against a federal judge and up to five years for each count of making threats in interstate commerce if convicted.
Threats targeting federal judges overall have more than doubled in recent years amid a surge of similar violent messages directed at public officials around the country, the U.S. Marshals Service previously said.
In 2022, shortly after the leak of a draft opinion overturning Roe v. Wade, a man was stopped near the home of Justice Brett Kavanaugh with weapons and zip ties.
ROME (AP) — Canadian and Italian dignitaries on Thursday marked the successful recovery of a photo portrait of Winston Churchill known as “The Roaring Lion,” stolen in Canada and recovered in Italy after a two-year search by police.
At a ceremony at the Canadian Embassy in Rome, Italian carabinieri police handed over the portrait to the Canadian ambassador to Italy, Elissa Goldberg, who praised the cooperation between Italian and Canadian investigators that led to the recovery.
The 1941 portrait of the British leader taken by Ottawa photographer Yousuf Karsh is now ready for the last step of its journey home to the Fairmont Château Laurier, the hotel in Ottawa where it was stolen and will once again be displayed as a notable historic portrait.
Canadian police said the portrait was stolen from the hotel sometime between Christmas 2021 and Jan. 6, 2022, and replaced with a forgery. The swap was only uncovered months later, in August, when a hotel worker noticed the frame was not hung properly and looked different than the others.
Nicola Cassinelli, a lawyer in Genoa, Italy, purchased the portrait in May 2022 at an online Sotheby’s auction for 5,292 British pounds. He says he got a phone call from the auction house that October advising him not to sell or otherwise transfer the portrait due to an investigation into the Ottawa theft.
Cassinelli, who attended Thursday’s ceremony, said he thought he was buying a regular print and quickly agreed to send the iconic Churchill photograph home when he learned its true story.
“I immediately decided to return it to the Chateau Laurier, because I think that if Karsh donated it to the hotel, it means he really wanted it to stay there, for the particular significance this hotel had for him, and for his wife too,” Cassinelli told The Associated Press.
The famous image was taken by Karsh during Churchill’s wartime visit to the Canadian Parliament in December 1941. It helped launch Karsh’s career, who photographed some of the 20th century’s most famed icons, including Nelson Mandela, Albert Einstein and Queen Elizabeth.
Karsh and his wife Estrellita gifted an original signed print to the Fairmont Chateau Laurier in 1998. The couple had lived and operated a studio inside the hotel for nearly two decades.
Geneviève Dumas, general manager of the Fairmont Château Laurier, said on Thursday she felt immensely grateful.
“I would like to extend my deepest gratitude to everybody involved in solving this case, and ensuring the safe return of this priceless piece of history.”
Police arrested a 43-year-old man from Powassan, Ontario, in April and have charged him with stealing and trafficking the portrait. The man, whose name is protected by a publication ban, faces charges that include forgery, theft over $5,000 and trafficking in property obtained by crime exceeding $5,000.
CULIACAN, Mexico (AP) — Mexican President Andrés Manuel López Obrador blamed the United States in part on Thursday for the surge in cartel violence terrorizing the northern state of Sinaloa which has left at least 30 people dead in the past week.
Two warring factions of the Sinaloa cartel have clashed in the state capital of Culiacan in what appears to be a fight for power since two of its leaders were arrested in the United States in late July. Teams of gunmen have shot at each other and the security forces.
Meanwhile, dead bodies continued to pop up around the city. On one busy street corner, cars drove by pools of the blood leading to a body in a car mechanic shop, while heavily armed police in black masks loaded up another body stretched out on a side street of the Sinaloan city.
Asked at his morning briefing if the U.S. government was “jointly responsible” for this violence in Sinaloa, the president said, “Yes, of course … for having carried out this operation.”
The recent surge in cartel warfare had been expected after Joaquín Guzmán López, a son of former Sinaloa cartel leader Joaquín “El Chapo” Guzmán, landed near El Paso, Texas on July 25 in a small plane with Ismael “El Mayo” Zambada.
Zambada was the cartel’s elder figure and reclusive leader. After his arrest, he said in a letter circulated by his lawyer that he had been abducted by the younger Guzmán and taken to the U.S. against his will.
On Thursday afternoon, another military operation covered the north of Culiacan with military and circling helicopters.
Traffic was heavy in Culiacan and most schools were open, even though parents were still not sending their children to classes. Businesses continue to close early and few people venture out after dark. While the city has slowly reopened and soldiers patrol the streets, many families continue to hide away, with parents and teachers fearing they’ll be caught in the crossfire.
“Where is the security for our children, for ourselves too, for all citizens? It’s so dangerous here, you don’t want to go outside,” one Culiacan mother told the Associated Press.
The mother, who didn’t want to share her name out of fear of the cartels, said that while some schools have recently reopened, she hasn’t allowed her daughter to go for two weeks. She said she was scared to do so after armed men stopped a taxi they were traveling in on their way home, terrifying her child.
During his morning press briefing, López Obrador had claimed American authorities “carried out that operation” to capture Zambada and that “it was totally illegal, and agents from the Department of Justice were waiting for Mr. Mayo.”
“If we are now facing instability and clashes in Sinaloa, it is because they (the American government) made that decision,” he said.
He added that there “cannot be a cooperative relationship if they take unilateral decisions” like this. Mexican prosecutors have said they were considering bringing treason charges against those involved in the plan to nab Zambada.
He was echoed by President-elect Claudia Sheinbaum, who said later in the day that “we can never accept that there is no communication or collaboration.”
It’s the latest escalation of tensions in the U.S.-Mexico relationship. Last month, the Mexican president said he was putting relations with the U.S. and Canadian embassies “on pause” after ambassadors criticized his controversial plan to overhaul Mexico’s judiciary by requiring all judges to stand for election.
Still, the Zambada capture has fueled criticisms of López Obrador, who has throughout his administration refused to confront cartels in a strategy he refers to as “hugs not bullets.” On previous occasions, he falsely stated that cartels respect Mexican citizens and largely fight amongst themselves.
While the president, who is set to leave office at the end of the month, has promised his plan would reduce cartel violence, such clashes continue to plague Mexico. Cartels employ an increasing array of tactics, including roadside bombs or IEDs, trenches, home-made armored vehicles and bomb-dropping drones.
