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No, the coronavirus was not genetically engineered in a Wuhan lab, expert says – National Post

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A scientist at the forefront of an international effort to track the deadly coronavirus outbreak has shot down claims about the disease’s origins, including that it escaped from a Wuhan laboratory after being genetically engineered.

Trevor Bedford, of the Fred Hutchinson Cancer Research Center in Seattle, rubbished stories circulating on social media that Covid-19 was created at Wuhan Institute of Virology or elsewhere in China, rumours that prompted the World Health Organization to warn of an “infodemic” of false news on the outbreak.

“There is no evidence whatsoever of genetic engineering that we can find,” he said at the American Association for the Advancement of Science meeting in Seattle. “The evidence we have is that the mutations (in the virus) are completely consistent with natural evolution.”

One source of rumours was a paper posted by scientists in India claiming that short insertions in the viral genome had an “uncanny similarity” to HIV. Although the paper was quickly withdrawn, its allegations live on in social media.

The research was “wrong on many levels,” said Dr. Bedford, whose lab studies the evolution of viruses. The genes it shares with HIV are extremely short sequences naturally shared by other organisms and “repeated again and again throughout the tree of life.”

He also disputed claims that Covid-19 might have infected humans from snakes or even fish. The most likely scenario, based on genetic analysis, was that the virus was transmitted by a bat to another mammal between 20-70 years ago.

This intermediary animal — not yet identified — passed it on to its first human host in the city of Wuhan in late November or early December 2019.

Dr. Bedford is a leader of the worldwide Nextstrain collaboration that began to analyze Covid-19 genomes when they were released in January by Fudan University and the Chinese Centre for Disease Control. By now scientists around the world have published the genetic sequence of virus taken from about 100 patients.


This file photo taken on January 25, 2020 shows medical staff members wearing protective clothing, walking at the Wuhan Red Cross Hospital in Wuhan.

HECTOR RETAMAL/AFP via Getty Images

They show mutations taking place at a slow pace as the infection passes from person to person.

Typically the virus in one patient today is different in around five of the 30,000 biochemical letters of its genetic code, but these are random changes rather than any sign that it is becoming more virulent or infectious, Dr. Bedford said.

By comparing virus taken from different patients and knowing its mutation rate, he and his colleagues can also estimate the total number of cases so far. He said the result was similar to that produced by more conventional epidemiology.

There is no evidence whatsoever of genetic engineering that we can find

“We get upwards of 200,000 total infections, which fits with the estimates already published by Neil Ferguson and colleagues at Imperial College London,” Dr Bedford said. But he was reluctant to forecast the future course of the epidemic.

The death toll from the virus was on Friday approaching 1,500 with more than 64,000 case identified, according to Chinese state media. But medical experts and frontline health workers in China have warned that Beijing is under-reporting the severity of the outbreak.

Copyright The Financial Times Limited 2020
© 2020 The Financial Times Ltd. All rights reserved. Please do not copy and paste FT articles and redistribute by email or post to the web.

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Canada to donate up to 200,000 vaccine doses to combat mpox outbreaks in Africa

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The Canadian government says it will donate up to 200,000 vaccine doses to fight the mpox outbreak in Congo and other African countries.

It says the donated doses of Imvamune will come from Canada’s existing supply and will not affect the country’s preparedness for mpox cases in this country.

Minister of Health Mark Holland says the donation “will help to protect those in the most affected regions of Africa and will help prevent further spread of the virus.”

Dr. Madhukar Pai, Canada research chair in epidemiology and global health, says although the donation is welcome, it is a very small portion of the estimated 10 million vaccine doses needed to control the outbreak.

Vaccine donations from wealthier countries have only recently started arriving in Africa, almost a month after the World Health Organization declared the mpox outbreak a public health emergency of international concern.

A few days after the declaration in August, Global Affairs Canada announced a contribution of $1 million for mpox surveillance, diagnostic tools, research and community awareness in Africa.

On Thursday, the Africa Centres for Disease Control and Prevention said mpox is still on the rise and that testing rates are “insufficient” across the continent.

Jason Kindrachuk, Canada research chair in emerging viruses at the University of Manitoba, said donating vaccines, in addition to supporting surveillance and diagnostic tests, is “massively important.”

But Kindrachuk, who has worked on the ground in Congo during the epidemic, also said that the international response to the mpox outbreak is “better late than never (but) better never late.”

“It would have been fantastic for us globally to not be in this position by having provided doses a much, much longer time prior than when we are,” he said, noting that the outbreak of clade I mpox in Congo started in early 2023.

Clade II mpox, endemic in regions of West Africa, came to the world’s attention even earlier — in 2022 — as that strain of virus spread to other countries, including Canada.

Two doses are recommended for mpox vaccination, so the donation may only benefit 100,000 people, Pai said.

Pai questioned whether Canada is contributing enough, as the federal government hasn’t said what percentage of its mpox vaccine stockpile it is donating.

“Small donations are simply not going to help end this crisis. We need to show greater solidarity and support,” he said in an email.

“That is the biggest lesson from the COVID-19 pandemic — our collective safety is tied with that of other nations.”

This report by The Canadian Press was first published Sept. 13, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

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How many Nova Scotians are on the doctor wait-list? Number hit 160,000 in June

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HALIFAX – The Nova Scotia government says it could be months before it reveals how many people are on the wait-list for a family doctor.

The head of the province’s health authority told reporters Wednesday that the government won’t release updated data until the 160,000 people who were on the wait-list in June are contacted to verify whether they still need primary care.

Karen Oldfield said Nova Scotia Health is working on validating the primary care wait-list data before posting new numbers, and that work may take a matter of months. The most recent public wait-list figures are from June 1, when 160,234 people, or about 16 per cent of the population, were on it.

“It’s going to take time to make 160,000 calls,” Oldfield said. “We are not talking weeks, we are talking months.”

The interim CEO and president of Nova Scotia Health said people on the list are being asked where they live, whether they still need a family doctor, and to give an update on their health.

A spokesperson with the province’s Health Department says the government and its health authority are “working hard” to turn the wait-list registry into a useful tool, adding that the data will be shared once it is validated.

Nova Scotia’s NDP are calling on Premier Tim Houston to immediately release statistics on how many people are looking for a family doctor. On Tuesday, the NDP introduced a bill that would require the health minister to make the number public every month.

“It is unacceptable for the list to be more than three months out of date,” NDP Leader Claudia Chender said Tuesday.

Chender said releasing this data regularly is vital so Nova Scotians can track the government’s progress on its main 2021 campaign promise: fixing health care.

The number of people in need of a family doctor has more than doubled between the 2021 summer election campaign and June 2024. Since September 2021 about 300 doctors have been added to the provincial health system, the Health Department said.

“We’ll know if Tim Houston is keeping his 2021 election promise to fix health care when Nova Scotians are attached to primary care,” Chender said.

This report by The Canadian Press was first published Sept. 11, 2024.

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Newfoundland and Labrador monitoring rise in whooping cough cases: medical officer

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ST. JOHN’S, N.L. – Newfoundland and Labrador‘s chief medical officer is monitoring the rise of whooping cough infections across the province as cases of the highly contagious disease continue to grow across Canada.

Dr. Janice Fitzgerald says that so far this year, the province has recorded 230 confirmed cases of the vaccine-preventable respiratory tract infection, also known as pertussis.

Late last month, Quebec reported more than 11,000 cases during the same time period, while Ontario counted 470 cases, well above the five-year average of 98. In Quebec, the majority of patients are between the ages of 10 and 14.

Meanwhile, New Brunswick has declared a whooping cough outbreak across the province. A total of 141 cases were reported by last month, exceeding the five-year average of 34.

The disease can lead to severe complications among vulnerable populations including infants, who are at the highest risk of suffering from complications like pneumonia and seizures. Symptoms may start with a runny nose, mild fever and cough, then progress to severe coughing accompanied by a distinctive “whooping” sound during inhalation.

“The public, especially pregnant people and those in close contact with infants, are encouraged to be aware of symptoms related to pertussis and to ensure vaccinations are up to date,” Newfoundland and Labrador’s Health Department said in a statement.

Whooping cough can be treated with antibiotics, but vaccination is the most effective way to control the spread of the disease. As a result, the province has expanded immunization efforts this school year. While booster doses are already offered in Grade 9, the vaccine is now being offered to Grade 8 students as well.

Public health officials say whooping cough is a cyclical disease that increases every two to five or six years.

Meanwhile, New Brunswick’s acting chief medical officer of health expects the current case count to get worse before tapering off.

A rise in whooping cough cases has also been reported in the United States and elsewhere. The Pan American Health Organization issued an alert in July encouraging countries to ramp up their surveillance and vaccination coverage.

This report by The Canadian Press was first published Sept. 10, 2024.

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