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COVID news: Hope for those having symptoms years later

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TORONTO –

Four years ago, Sonja Mally was a busy tattoo artist with a photographic memory and penchant for long hikes.

Now, the 38-year-old Toronto woman considers it a good day if she can do a small drawing, muster the energy to walk around the block or “perform very basic tasks.”

“It’s a hard thing to have to explain to people why maybe one day you might be doing fine and the next day you can’t find the words to complete a sentence,” Mally said.

Debilitating long-COVID symptoms ended the career she loved and forced her to go on Ontario government disability payments, which she supplements with some part-time administrative work.

Mally’s world changed in March 2020, when she got what she thought was a mild cold – “nothing that I thought was going to slow me down.”

“It was what happened afterwards that was devastating for me.”

That COVID-19 infection led to respiratory problems and extreme fatigue. Then came more terrifying symptoms, including brain fog so severe that the artist couldn’t draw a clock during a neurology exam, as well as “excruciating pain” that “felt like my veins were on fire.”

The biggest difference between now and then, Mally said, is that the health-care community now recognizes long COVID is real.

“I don’t have to have that battle with medical practitioners (anymore) trying to convince them that this condition that I have exists.”

A recent Statistics Canada report estimated 3.5 million people in Canada, or 11.7 per cent of the adult population, reported “long-term symptoms” lasting at least three months after COVID-19 infection as of June 2023.

Many of those meet the World Health Organization’s definition of long COVID – also called post-COVID-19 condition – which is “the continuation or development of new symptoms three months after the initial SARS-CoV-2 infection, with these symptoms lasting for at least two months with no other explanation.”

Forty-two per cent of the people in Canada reporting lasting symptoms had them for a year or more – and for many, they haven’t resolved, StatCan’s report said.

But Canadian doctors and scientists want long COVID patients to know that research is accelerating.

Long COVID Web, a research network of close to 600 health-care practitioners, scientists and patients across Canada, aims to not only help manage symptoms, but also find “solutions to get rid of long COVID,” said Dr. Angela Cheung, the network’s lead and a senior physician-scientist at University Health Network in Toronto.

Long COVID affects many different systems in the body, Cheung said, with the most common symptoms including fatigue, brain fog, cardiovascular problems and shortness of breath.

Cheung has seen many patients improve, and “quite a few” have even returned to their “baseline” functioning before COVID.

“Why some can return to baseline and others cannot, I’m not sure. But certainly it’s something that we need to better understand,” she said.

Susie Goulding of Cambridge, Ont., got infected around the same time as Mally back in 2020 and said she could barely function with similarly life-changing symptoms.

She gradually improved enough to run her flower shop and care for her 15-year-old son, but she still struggles with lingering brain fog.

“I think I’ve healed to a plateau,” said Goulding, 56.

“I have a lot of issues with word-finding and with the stamina of my brain. I can only do so much.”

A few months into her illness, Goulding started a Facebook group called COVID Long-Haulers Support Group Canada. Three and a half years later, there are close to 20,000 members, she said.

“It just kills me when people join our group and they said they had no idea (this could happen to them). You know, it’s sad,” she said.

Many long COVID patients live in fear of getting reinfected with COVID-19, or any other virus, because it can wipe out any recovery gains they’ve made, said Goulding.

“It’s really like the world has forgotten about COVID and has moved on and all of the safety precautions that were meant to keep people safe are no longer there,” she said.

“And so we have to navigate through the world as best as we can with our safety parameters in mind.”

Mally had a glimpse of hope last year, when she was “finally able to walk, go for little hikes again … I was just functioning on a much more normal kind of level.”

But she was only able to enjoy it for a couple of months before she caught a cold, despite taking precautions such as masking.

“I lost all that progress. I was in bed again for months and unable to do anything,” she said. “I’m still trying to work my way back from that.”

One dangerous misconception is that long COVID only happened to people who were infected earlier in the pandemic, said researchers.

Cheung said it’s possible the Omicron variant carries a smaller risk of long COVID than the previous Alpha or Delta variants did, but the risk is still significant because so many more people are infected with Omicron.

“This variant can and does cause long COVID,” said Dr. Jim Russell, a professor of medicine at the University of British Columbia and another researcher for Long COVID Web.

There’s growing evidence that vaccinations not only protect against dying and hospitalizations but against long COVID too, Russell said.

Like Cheung, Russell is hopeful they will find ways to treat long COVID by getting at the root of what causes it.

“I can’t help but believe that between Europe, U.S., Australia, Canada, we’re going to start seeing breakthroughs within the next year,” he said.

One of the main theories Russell is studying is overactive or sustained inflammation.

“When you get infected, your body turns on an inflammatory response to kill the virus … and you need that inflammatory response to recover,” Russell said.

“(But) this inflammation, unfortunately, doesn’t turn off in some people, and it keeps going for months,” likely damaging organs including the lungs and the brain that lead to long COVID symptoms, he said.

Researchers are also looking at immune system dysregulation, disruption of the microbiome in the gut, damage to endothelial cells in organs and unusual persistence of the virus in the body as other plausible theories for causes of long COVID.

Goulding, who joined the patient advisory group for Long COVID Web, said these are encouraging developments for long COVID sufferers.

“Don’t give up hope yet,” she said.

“When the research is just getting rolling, you know, there are going to be interventions that are going to help people.”

This report by The Canadian Press was first published Dec.15, 2023.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

 

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With grief lingering, Blue Jackets GM Waddell places focus on hockey in wake of Gaudreau’s death

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BUFFALO, N.Y. (AP) — Hearing the familiar sounds of clacking sticks and pucks banging off the boards and glass while watching Columbus Blue Jackets prospects from the stands of a cold rink on a warm late-summer afternoon was not enough to wash away the lingering residuals of grief for Don Waddell on Saturday.

That, the Blue Jackets’ general manager acknowledged, will take more time than anyone can guess — weeks, months, perhaps an entire season and beyond.

What mattered is how spending the weekend attending the Sabres Prospects Challenge represented a start to what Waddell called among the first steps in refocusing on hockey and the future in the aftermath of the deaths of Columbus star Johnny Gaudreau and his brother, Matthew, who were struck by a suspected drunken driver while riding bicycles on Aug 29.

“We got to play hockey,” Waddell said. “We’re not going to forget about Johnny and his family, the Gaudreau family.”

He then reflected on the speech Johnny Gaudreau’s wife, Meredith, made during the brothers’ funeral on Monday, by urging those in mourning to move forward as she will while focusing on raising their children.

“Everybody knows that Johnny wants them to play hockey,” Waddell said. “And everybody’s rallying around that.”

The resumption of hockey in Columbus began last week, when most Blue Jackets players returned to their facility to be together and lean on each other at the urging of Waddell and team captain Boone Jenner. And it will continue on Thursday, when the team opens training camp, exactly three weeks since the Gaudreaus were killed.

“Tragic. Senseless. But now we got to focus on trying to get our team ready to play hockey this year,” Waddell said. “We all mourn and heal differently, but I think as a team being together like that is going to be critical for them to get moving forward.”

Tragedy is no stranger to Waddell or the Blue Jackets.

Waddell was general manager of the then-Atlanta Thrashers in 2003 when Dany Heatley lost control of his car and struck a wall, with the crash killing passenger and teammate Dan Snyder. In 2021, Blue Jackets goalie Matiss Kivlenieks died during a July Fourth fireworks accident.

Waddell placed the emphasis on himself and coach Dean Evason — both newcomers to Columbus this offseason — to guide the team through what will be an emotional season.

“Now, do I think there’s going to be some dark days? I won’t be surprised,” Waddell said.

Reminders of the Gaudreaus’ deaths remain apparent, and reflected in Buffalo on Friday night. A moment of silence was held in tribute to the brothers before the opening faceoff of a game between the Blue Jackets and Sabres.

Afterward, Columbus prospect Gavin Brindley recalled the times he spent with Johnny Gaudreau in Columbus and as teammates representing the United States at the world hockey championships in the Czech Republic in May.

“He was one of the biggest mentors for me at the world championships,” Brindley said. “I couldn’t tell you how many times we hung out with Meredith, pictures on my phone. It’s just so hard to look back and see that kind of stuff.”

The NHL and NHL Players’ Association are providing the Blue Jackets help in the form of grief counseling, crowd security at vigils and addressing hockey issues, such as potentially altering the league’s salary cap rules to provide Columbus relief from having to reach the NHL minimum payroll because of the void left by Gaudreau’s contract.

“The Blue Jackets, I don’t think anybody’s focused from an organizational standpoint, from a hockey standpoint as to what comes next, because I think everybody’s still in shock,” NHL Commissioner Gary Bettman told The Associated Press last week. “I don’t think anybody’s focused right now other than on the grieving part, which is understandable.”

Much of the burden has fallen to Waddell, who has been in discussions with the NHL and the NHLPA and dealing with outreach programs with the Blue Jackets’ partner OhioHealth, while also overseeing preparations for training camp and gauging his prospects in Buffalo.

There’s also his roster to attend to, which he said has two openings at forward, one involving Justin Danforth, who may miss the start of the season because of a wrist injury. Waddell didn’t have to mention the second opening.

Tiring and emotional as it’s been, Waddell found comfort being in his element, a rink, and looking ahead to the start of training camp.

“The guys are in really good shape. We’ve done a lot of testing already and they’re eager to get going,” Waddell said. “We have a reason to play for. And we’ll make the best of it.”

The Blue Jackets later Sunday signed veteran winger James van Riemsdyk to a one-year contract worth $900,000.

“James van Riemsdyk has been a very consistent, productive player throughout his career,” Waddell said. “Bringing him to Columbus will not only provide depth to our group up front, but also valuable leadership and another veteran presence in our dressing room.”

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AP Hockey Writer Stephen Whyno in New York contributed to this report.

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PSG says defender Nuno Mendes target of racial abuse after a French league game

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PARIS (AP) — Paris Saint-Germain defender Nuno Mendes was the target of abusive and racist comments on social media after a French league game.

The club condemned the abuse and expressed its “full support” Sunday for the Portugal left back, who was targeted following PSG’s 3-1 win against Brest on Saturday.

Mendes, who is Black, shared on his Instagram account a racist message he received.

During the match, Mendes brought down Ludovic Ajorque in the box for a penalty that Romain Del Castillo converted to give Brest the lead.

“Paris Saint-Germain doesn’t tolerate racism, antisemitism or any other form of discrimination,” the club said. “The racial insults directed at Nuno Mendes are totally unacceptable … we are working with the relevant authorities and associations to ensure those responsible are held accountable for their actions.”

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Slovenia’s Tadej Pogacar wins Grand Prix Cycliste de Montreal

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MONTREAL – Tadej Pogacar was so dominant on Sunday, Canada’s Michael Woods called it a race for second.

Pogacar, a three-time Tour de France champion from Slovenia, pedalled to a resounding victory at the Grand Prix Cycliste de Montreal.

The UAE Team Emirates leader crossed the finish line 24 seconds ahead of Spain’s Pello Bilbao of Bahrain — Victorious to win the demanding 209.1-kilometre race on a sunny, 28 C day in Montreal. France’s Julian Alaphilippe of Soudal Quick-Step was third.

“He’s the greatest rider of all time, he’s a formidable opponent,” said Woods, who finished 45 seconds behind the leader in eighth. “If you’re not at your very, very best, then you can forget racing with him, and today was kind of representative of that.

“He’s at such a different level that if you follow him, it can be lights out.”

Pogacar slowed down before the last turn to celebrate with the crowd, high-five fans on Avenue du Parc and cruise past the finish line with his arms in the air after more than five hours on the bike.

The 25-year-old joined Belgium’s Greg Van Avermaet as the only multi-time winners in Montreal after claiming the race in 2022. He also redeemed a seventh-place finish at the Quebec City Grand Prix on Friday.

“I was disappointed, because I had such good legs that I didn’t do better than seventh,” Pogacar said. “To bounce back after seventh to victory here, it’s just an incredible feeling.”

It’s Pogacar’s latest win in a dominant year that includes victories at the Tour de France and Giro d’Italia.

Ottawa’s Woods (Israel Premier-Tech) tied a career-best in front of the home crowd in Montreal, but hoped for more after claiming a stage at the Spanish Vuelta two weeks ago.

“I wanted a better result,” the 37-year-old rider said. “My goal was a podium, but at the same time I’m happy with the performance. In bike racing, you can’t always get the result you want and I felt like I raced really well, I animated the race, I felt like I was up there.”

Pogacar completed the 17 climbs up and down Mount Royal near downtown in five hours 28 minutes 15 seconds.

He made his move with 23.3 kilometres to go, leaving the peloton in his dust as he pedalled into the lead — one he never relinquished.

Bilbao, Alaphilippe, Alex Aranburu (Movistar Team) and Bart Lemmen (Visma–Lease) chased in a group behind him, with Bilbao ultimately separating himself from the pack. But he never came close to catching Pogacar, who built a 35-second lead with one lap left to go.

“It was still a really hard race today, but the team was on point,” Pogacar said. “We did really how we planned, and the race situation was good for us. We make it hard in the last final laps, and they set me up for a (takeover) two laps to go, and it was all perfect.”

Ottawa’s Derek Gee, who placed ninth in this year’s Tour de France, finished 48th in Montreal, and called it a “hard day” in the heat.

“I think everyone knows when you see Tadej on the start line that it’s just going to be full gas,” Gee said.

Israel Premier-Tech teammate Hugo Houle of Sainte-Perpétue, Que., was 51st.

Houle said he heard Pogacar inform his teammates on the radio that he was ready to attack with two laps left in the race.

“I said then, well, clearly it’s over for me,” Houle said. “You see, cycling isn’t that complicated.”

Australia’s Michael Matthews won the Quebec City GP for a record third time on Friday, but did not finish in Montreal. The two races are the only North American events on the UCI World Tour.

Michael Leonard of Oakville, Ont., and Gil Gelders and Dries De Bondt of Belgium broke away from the peloton during the second lap. Leonard led the majority of the race before losing pace with 45 kilometres to go.

Only 89 of 169 riders from 24 teams — including the Canadian national team — completed the gruelling race that features 4,573 metres in total altitude.

Next up, the riders will head to the world championships in Zurich, Switzerland from Sept. 21 to 29.

Pogacar will try to join Eddy Merckx (1974) and Stephen Roche (1987) as the only men to win three major titles in a season — known as the Triple Crown.

“Today gave me a lot of confidence, motivation,” Pogacar said. “I think we are ready for world championships.”

This report by The Canadian Press was first published Sept. 15, 2024.



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