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Ethical requirements of instructions for authors of complementary and alternative medicine journals: a cross-sectional study

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Initially, 30 CAM journals were retrieved from JCR (2021). After reviewing the aims and scope of each journal, PLANTA MEDICA and Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas were excluded because the acceptance scopes of these 2 journals did not include biomedical research involving humans, BMC Complementary and Alternative Medicine was excluded from Q1 section due to the change to BMC Complementary Medicine and Therapies, finally, 27 journals remained.

General information about included journals

The 27 journals originated in eight different nations and areas (Table 1). Ten journals were from the United States, five from England, four from China’s mainland, three from Germany, two from South Korea, and one each from Ireland, the Netherlands, and Taiwan, China (Fig. 2). 27 journals were published by 12 different publishers.

Table 1 General information about included journals
Fig. 2

Countries and regions of 27 CAM journals

The requirements for ethical review in IFAs

Of the 27 journals included in the study, 92.6% (25/27) IFAs contained keywords of “ethic(s)”, “ethical”, or “human” in the subtitles and text words, which represented there were ethical considerations in these journals. Of these, 84.0% (21/25) explicitly mentioned that the manuscript of biomedical research involving human subjects should undergo ethical review; 12.0% (3/25) IFAs’ (Journal of Integrative Medicine, Journal of Herbal Medicine, ACUPUNCTURE & ELECTRO-THERAPEUTICS RESEARCH) content of ethical review regarding the policy of publishing ethics most and authors needed to read IFAs carefully to search for key information; 4.0% (1/25) only mentioned ethics in publication (Holistic Nursing Practice). 7.4% (2/27) IFAs of journals (Phytomedicine, Chinese Journal of Integrative Medicine) had no clear claim to ethical review of medical research involving human subjects in the subtitles or text words of their IFAs, but there was an “ethics disclosures” on the official website page of Chinese Journal of Integrative Medicine, IFA of Phytomedicine declared that “the author should ensure that the manuscript contains a statement that all procedures were performed in compliance with relevant laws and institutional guidelines and that the appropriate institutional committee(s) have approved them”.

Citation situation of the DoH, ICMJE recommendations, and COPE Core Practice

In this study, 81.5% (22/27) of the IFAs mentioned the Declaration of Helsinki (DoH), 70.4% (19/27) of the IFAs mentioned ICMJE recommendations. 21 journals are members of COPE, although 3 journals had not yet become members of COPE, their IFAs also required authors to follow COPE core practice.

In addition to the above international general guidelines for ethical review, the IFAs of Phytomedicine recommended that authors comply with ICH-E6 Good Clinical Practice [17]. Policy Statement on Geopolitical Intrusion on Editorial Decisions issued by the World Association of Medical Editors (WAME), UK’s The Medicines for Human Use (Clinical Trials) Regulations, ICMJE Recommendations for the Protection of Research Participants, NLM’s Research Reporting Guidelines, and Initiatives and Guidelines for the Conduct of Human Embryonic Stem Cell Research established by the International Society for Stem Cell Research (ISSCR) always appeared in IFAs.

The results showed there was no statistical significance in the citation of the DoH, ICMJE recommendations and COPE core practice in any classification of journals (p > 0.05, Table 2). For the factors related to journals that we have taken into account above, they were not influencing factors for CAM journals to make a particular ethical review request. We integrated journals that cited the above three documents (the DoH, ICMJE recommendations, COPE guidelines) at the same time, and calculated their mean value IF: 3.20 (3.05), mean value years of electronic JCR: 8.8 (14.9), median % OA GOLD: 14.97% (5.42%), and the data of journals that do not cite the above three documents are in parentheses.

Table 2 Content of ethical review of journals of Q1 section versus journals of Q2-Q4 section

The requirements of IRB approval, name of IRB, IRB approval number, registration and reporting guidelines

Many journals also requested informations on IRB, but Geographic origin, JCR section, Year of electronic JCR, Types of studies, % of OA Gold were not associated with requirements of IRB approval, name of IRB, IRB approval number, registration and reporting guidelines separately (p > 0.05, Table 2). Some journals required that the authors provide the details (JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE) of the ethical review process and the date of ethical review (American Journal of Chinese Medicine) along with manuscripts.

Policies of IC, images privacy and data sharing

In addition to adhering to the international guidelines mentioned above, some journals emphasized the principles of IC and patient privacy. 81.5% (22/27) of journals mentioned obtaining IC from patients, some of the journals (Journal of Traditional and Complementary Medicine, COMPLEMENTARY THERAPIES IN MEDICINE, INTEGRATIVE CANCER THERAPIES) required that patients’ handwritten IC be retained and backed up, some of the journals (Complementary Medicine Research, JOURNAL OF MANIPULATIVE AND PHYSIOLOGICAL THERAPEUTICS) required authors to provide a statement of detailed procedure in obtaining IC. Among these journals, 50.0% (11/22) of them proposed protecting patient privacy as well. As for the use of patients’ images and photographs, 51.9% (14/27) of the journals emphasized the need to obtain IC from patients before using their photos, and that some identifying information should be hidden, but there were no more separate and specific consent was required. 77.8% (21/27) of journals promoted data sharing and make research more transparent, these journals encouraged authors to share their research data, which refers to the “results of observations or experimentation that validate research findings”, but there were no policies relevant for personal data protection.

We integrated journals which had a requirement of IRB approval, name of IRB, IRB approval number, registration, reporting guidelines along with IC, and calculated their mean value IF: 2.96 (3.19), mean value years of electronic JCR: 6.7 (13.7), median % OA GOLD: 98.71% (7.03%), and the data of journals that do not have the requirements above are in parentheses.

It seems that CAM journals which were included in electronic JCR in recent years, and the higher the % OA GOLD, will have more comprehensive requirements for ethical review.

The actual situation of ethical requirement in published manuscripts

We also browsed the manuscripts regarding randomized controlled trials (RCT) published by CAM journals in Q1 and Q2 section from January to June, 2023, to check the actual situation of ethical requirement. There were 68 manuscripts (20 from Q1 section, 48 from Q2 section) in total (Table 3). Of the 20 randomized controlled studies included in Q1, 11 studies were from China, 4 from Korea, 2 from Iran, and 1 from Brazil, Australia, and the United States, respectively. 95.00% (19/20) manuscripts mentioned that their research had been registered on the website, 90.00% (18/20) of which also gave registration numbers, and only one [18] did not mention any registration information about the clinical trial. Of the 48 randomized controlled studies included in Q2, 95.83% (46/48) manuscripts mentioned that their research had been registered on the website, 91.67% (44/48) of which gave registration numbers, 4.17% (2/48) manuscripts [19, 20] did not contain the information about trial registration. In Q1 section, all the manuscripts mentioned the name of the REC/IRB, and 95% (19/20) of the studies also clearly indicated the ethics review number, while one study, from China [21] published in Chinese Medicine did not specify the ethics review number, which is actually not in accordance with the requirements of the journal. In Q2 section, 6.25% (3/48) manuscripts did not mention any information of REC/IRB and ethics review number. Of the remaining 45 studies, 3 studies published in Complementary Therapies in Clinical Practice and 1 study published in COMPLEMENTARY THERAPIES IN MEDICINE only had the name of the ethics review committee, which was not requested by either journal, and 2 studies published in INTEGRATIVE CANCER THERAPIES and 3 studies published in BMC Complementary Medicine and Therapies only had the name of the ethics review committee without mentioning the ethics review number either, although both journals made clear requests for the provision of the ethics review number.

Table 3 Actual situation of ethical requirement in published manuscripts in Q1 and Q2 section

As for obtaining IC forms from patients, it was obtained from study subjects in all 68 studies, 95% (19/20) studies in Q1 section and 72.92% (35/48) studies in Q2 section mentioned that it was signing an IC form, the others were unknown.

Of all 68 manuscripts, only 4 manuscripts in Q1 section mentioned compliance with the DoH, while 28 manuscripts in Q2 section mentioned the DoH. Beyond that, there was no reference to other internationally recognized guiding principles mentioned.

 

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Here’s how Helene and other storms dumped a whopping 40 trillion gallons of rain on the South

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More than 40 trillion gallons of rain drenched the Southeast United States in the last week from Hurricane Helene and a run-of-the-mill rainstorm that sloshed in ahead of it — an unheard of amount of water that has stunned experts.

That’s enough to fill the Dallas Cowboys’ stadium 51,000 times, or Lake Tahoe just once. If it was concentrated just on the state of North Carolina that much water would be 3.5 feet deep (more than 1 meter). It’s enough to fill more than 60 million Olympic-size swimming pools.

“That’s an astronomical amount of precipitation,” said Ed Clark, head of the National Oceanic and Atmospheric Administration’s National Water Center in Tuscaloosa, Alabama. “I have not seen something in my 25 years of working at the weather service that is this geographically large of an extent and the sheer volume of water that fell from the sky.”

The flood damage from the rain is apocalyptic, meteorologists said. More than 100 people are dead, according to officials.

Private meteorologist Ryan Maue, a former NOAA chief scientist, calculated the amount of rain, using precipitation measurements made in 2.5-mile-by-2.5 mile grids as measured by satellites and ground observations. He came up with 40 trillion gallons through Sunday for the eastern United States, with 20 trillion gallons of that hitting just Georgia, Tennessee, the Carolinas and Florida from Hurricane Helene.

Clark did the calculations independently and said the 40 trillion gallon figure (151 trillion liters) is about right and, if anything, conservative. Maue said maybe 1 to 2 trillion more gallons of rain had fallen, much if it in Virginia, since his calculations.

Clark, who spends much of his work on issues of shrinking western water supplies, said to put the amount of rain in perspective, it’s more than twice the combined amount of water stored by two key Colorado River basin reservoirs: Lake Powell and Lake Mead.

Several meteorologists said this was a combination of two, maybe three storm systems. Before Helene struck, rain had fallen heavily for days because a low pressure system had “cut off” from the jet stream — which moves weather systems along west to east — and stalled over the Southeast. That funneled plenty of warm water from the Gulf of Mexico. And a storm that fell just short of named status parked along North Carolina’s Atlantic coast, dumping as much as 20 inches of rain, said North Carolina state climatologist Kathie Dello.

Then add Helene, one of the largest storms in the last couple decades and one that held plenty of rain because it was young and moved fast before it hit the Appalachians, said University of Albany hurricane expert Kristen Corbosiero.

“It was not just a perfect storm, but it was a combination of multiple storms that that led to the enormous amount of rain,” Maue said. “That collected at high elevation, we’re talking 3,000 to 6000 feet. And when you drop trillions of gallons on a mountain, that has to go down.”

The fact that these storms hit the mountains made everything worse, and not just because of runoff. The interaction between the mountains and the storm systems wrings more moisture out of the air, Clark, Maue and Corbosiero said.

North Carolina weather officials said their top measurement total was 31.33 inches in the tiny town of Busick. Mount Mitchell also got more than 2 feet of rainfall.

Before 2017’s Hurricane Harvey, “I said to our colleagues, you know, I never thought in my career that we would measure rainfall in feet,” Clark said. “And after Harvey, Florence, the more isolated events in eastern Kentucky, portions of South Dakota. We’re seeing events year in and year out where we are measuring rainfall in feet.”

Storms are getting wetter as the climate change s, said Corbosiero and Dello. A basic law of physics says the air holds nearly 4% more moisture for every degree Fahrenheit warmer (7% for every degree Celsius) and the world has warmed more than 2 degrees (1.2 degrees Celsius) since pre-industrial times.

Corbosiero said meteorologists are vigorously debating how much of Helene is due to worsening climate change and how much is random.

For Dello, the “fingerprints of climate change” were clear.

“We’ve seen tropical storm impacts in western North Carolina. But these storms are wetter and these storms are warmer. And there would have been a time when a tropical storm would have been heading toward North Carolina and would have caused some rain and some damage, but not apocalyptic destruction. ”

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Follow AP’s climate coverage at https://apnews.com/hub/climate

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Follow Seth Borenstein on Twitter at @borenbears

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Associated Press climate and environmental coverage receives support from several private foundations. See more about AP’s climate initiative here. The AP is solely responsible for all content.

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‘Big Sam’: Paleontologists unearth giant skull of Pachyrhinosaurus in Alberta

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It’s a dinosaur that roamed Alberta’s badlands more than 70 million years ago, sporting a big, bumpy, bony head the size of a baby elephant.

On Wednesday, paleontologists near Grande Prairie pulled its 272-kilogram skull from the ground.

They call it “Big Sam.”

The adult Pachyrhinosaurus is the second plant-eating dinosaur to be unearthed from a dense bonebed belonging to a herd that died together on the edge of a valley that now sits 450 kilometres northwest of Edmonton.

It didn’t die alone.

“We have hundreds of juvenile bones in the bonebed, so we know that there are many babies and some adults among all of the big adults,” Emily Bamforth, a paleontologist with the nearby Philip J. Currie Dinosaur Museum, said in an interview on the way to the dig site.

She described the horned Pachyrhinosaurus as “the smaller, older cousin of the triceratops.”

“This species of dinosaur is endemic to the Grand Prairie area, so it’s found here and nowhere else in the world. They are … kind of about the size of an Indian elephant and a rhino,” she added.

The head alone, she said, is about the size of a baby elephant.

The discovery was a long time coming.

The bonebed was first discovered by a high school teacher out for a walk about 50 years ago. It took the teacher a decade to get anyone from southern Alberta to come to take a look.

“At the time, sort of in the ’70s and ’80s, paleontology in northern Alberta was virtually unknown,” said Bamforth.

When paleontogists eventually got to the site, Bamforth said, they learned “it’s actually one of the densest dinosaur bonebeds in North America.”

“It contains about 100 to 300 bones per square metre,” she said.

Paleontologists have been at the site sporadically ever since, combing through bones belonging to turtles, dinosaurs and lizards. Sixteen years ago, they discovered a large skull of an approximately 30-year-old Pachyrhinosaurus, which is now at the museum.

About a year ago, they found the second adult: Big Sam.

Bamforth said both dinosaurs are believed to have been the elders in the herd.

“Their distinguishing feature is that, instead of having a horn on their nose like a triceratops, they had this big, bony bump called a boss. And they have big, bony bumps over their eyes as well,” she said.

“It makes them look a little strange. It’s the one dinosaur that if you find it, it’s the only possible thing it can be.”

The genders of the two adults are unknown.

Bamforth said the extraction was difficult because Big Sam was intertwined in a cluster of about 300 other bones.

The skull was found upside down, “as if the animal was lying on its back,” but was well preserved, she said.

She said the excavation process involved putting plaster on the skull and wooden planks around if for stability. From there, it was lifted out — very carefully — with a crane, and was to be shipped on a trolley to the museum for study.

“I have extracted skulls in the past. This is probably the biggest one I’ve ever done though,” said Bamforth.

“It’s pretty exciting.”

This report by The Canadian Press was first published Sept. 25, 2024.

The Canadian Press. All rights reserved.

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The ancient jar smashed by a 4-year-old is back on display at an Israeli museum after repair

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TEL AVIV, Israel (AP) — A rare Bronze-Era jar accidentally smashed by a 4-year-old visiting a museum was back on display Wednesday after restoration experts were able to carefully piece the artifact back together.

Last month, a family from northern Israel was visiting the museum when their youngest son tipped over the jar, which smashed into pieces.

Alex Geller, the boy’s father, said his son — the youngest of three — is exceptionally curious, and that the moment he heard the crash, “please let that not be my child” was the first thought that raced through his head.

The jar has been on display at the Hecht Museum in Haifa for 35 years. It was one of the only containers of its size and from that period still complete when it was discovered.

The Bronze Age jar is one of many artifacts exhibited out in the open, part of the Hecht Museum’s vision of letting visitors explore history without glass barriers, said Inbal Rivlin, the director of the museum, which is associated with Haifa University in northern Israel.

It was likely used to hold wine or oil, and dates back to between 2200 and 1500 B.C.

Rivlin and the museum decided to turn the moment, which captured international attention, into a teaching moment, inviting the Geller family back for a special visit and hands-on activity to illustrate the restoration process.

Rivlin added that the incident provided a welcome distraction from the ongoing war in Gaza. “Well, he’s just a kid. So I think that somehow it touches the heart of the people in Israel and around the world,“ said Rivlin.

Roee Shafir, a restoration expert at the museum, said the repairs would be fairly simple, as the pieces were from a single, complete jar. Archaeologists often face the more daunting task of sifting through piles of shards from multiple objects and trying to piece them together.

Experts used 3D technology, hi-resolution videos, and special glue to painstakingly reconstruct the large jar.

Less than two weeks after it broke, the jar went back on display at the museum. The gluing process left small hairline cracks, and a few pieces are missing, but the jar’s impressive size remains.

The only noticeable difference in the exhibit was a new sign reading “please don’t touch.”

The Canadian Press. All rights reserved.

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