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Acceleration Consortium announces $1.2 million in funding for projects that accelerate scientific discovery

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Canada’s population is aging, and with that comes a host of new stressors on the health-care system — including an increasing number of hip and knee replacements. In a best-case scenario using current materials, a hip or knee replacement can last a maximum of 25 years. With average life expectancies trending upwards, the rate of subsequent surgeries to replace or fix hip and knee replacements is poised to grow as well — adding even more stress on the system. New materials are needed to help solve this problem.

Enter self-driving labs (SDLs). SDLs combine artificial intelligence, robotics and advanced computing to discover new materials and molecules for commercial, clinical and industrial use in a fraction of the usual time and cost.

Professor Yu Zou (MSE) will be using the tools SDLs offer in his quest to speed up the development of improved materials for hip and knee replacements. Zou and his team will leverage an SDL to rapidly test combinations of elements to find the alloys required for longer-lasting joint-replacements.

Zou’s work is but one example of the problems being tackled head-on by scientists who have received funding from the Acceleration Consortium’s (AC’s) Accelerate Grants. These 12 new research projects — including the one led by Zou — are either developing technologies that will support the development of SDLs or using SDL technologies to accelerate discovery. The AC is funding a diverse array of research efforts across nine departments in the Faculty of Applied Science & Engineering, the Faculty of Arts & Science, the Leslie Dan Faculty of Pharmacy and the University of Toronto Scarborough.

These research projects are made possible by the almost $200 million grant from the Canada First Research Excellence Fund (CFREF) awarded to the AC last April, the largest federal research grant ever awarded to a Canadian university. The projects being enabled by the grant promise innovative advances in fields ranging from health care and climate change to sustainable materials design and food waste-management.

“Using AI and automation to carry out more laboratory experiments in a smarter way, we’ve supercharged the process of scientific discovery,” says Professor Alán Aspuru-Guzik¸ director of the Acceleration Consortium and professor in the Departments of Chemistry and Computer Science in the Faculty of Arts & Science. “These 12 Accelerate Grants are not only an investment in science but are an investment in our future. The creativity and the diversity of thought shown by the researchers on these projects tells me that the materially different future that the Acceleration Consortium is striving for is achievable in our lifetime.”‍

The Acceleration Consortium awarded the 12 grants in three categories — Accelerate Seed, Accelerate Moonshot and Accelerate Translation:

  • Accelerate Seed grants build accelerated discovery capacity at U of T by helping faculty enter the field or collaborate with those already doing accelerated discovery.
  • Accelerate Moonshot grants support high-risk, high-reward grants that will make significant contributions to the development or use of SDLs.
  • Accelerate Translation grants support accelerated discovery projects with clear commercialization goals and justified/demonstrated market potential, as well as the implementation or scaling of knowledge mobilization activities, training, and community engagement.

Recipients of Accelerate Seed grants include:

  • Professor Eugenia Kumacheva, Department of Chemistry, Faculty of Arts & Science
    “Self-Driving Lab for the Synthesis of Upconversion Nanoparticles for Bioanalytical Sensing”
  • Professor Jay Werber, Department of Chemical Engineering & Applied Chemistry, Faculty of Applied Science & Engineering
    “Self-Driving Labs for the Development of Next-Generation Membranes for Pressure-Driven Separations”
  • Professor Leo Chou, Institute of Biomedical Engineering, Faculty of Applied Science & Engineering
    “High throughput discovery of peptoid-DNA nanocarriers for antisense oligonucleotide therapies”
  • Professor Nandita Vijaykumar, Department of Computer and Mathematical Sciences, University of Toronto Scarborough
    “An Efficient and Versatile Software Framework for AI-based Automation of Materials Discovery”
  • Professor Emily Moore, Institute for Studies in Transdisciplinary Engineering Education & Practice (ISTEP), Faculty of Applied Science & Engineering
    “Integrating environmental, social and economic factors into SDL processes”
  • Professor Joseph Williams, Department of Computer Science, Faculty of Arts & Science
    “Comparison of Traditional and Adaptive Experiment to Accelerate the Identification of MicroRNA in a High Through-put Acute Respiratory Disease Syndrome In Vitro Model”
  • Professor Kai Huang, Department of Materials Science & Engineering, Faculty of Applied Science & Engineering
    “Automated and AI-driven Fluidic Synthesis of Lanthanide-Based Nanocrystals”

Accelerate Moonshot grants have been awarded to:

  • Professor Yu Zou, Department of Materials Science & Engineering, Faculty of Applied Science & Engineering
    “Accelerated Discovery of Revolutionary Materials for Biomedical Implants”
  • Professor David Sinton, Department of Mechanical & Industrial Engineering, Faculty of Applied Science & Engineering
    “Enabling self-driving electrocatalyst discovery: From A3MDs high-throughput electrocatalysis to the inorganic SDL1”
  • Professor Milica Radisic, Institute of Biomedical Engineering and Department of Chemical Engineering & Applied Chemistry, Faculty of Applied Science & Engineering
    “Self-driving platform technology for vascularized human organ mimicry”
  • Professor Christopher Lawson, Department of Chemical Engineering & Applied Chemistry, Faculty of Applied Science & Engineering
    “Accelerated design and assembly of synthetic microbial communities for sustainable chemicals manufacturing”

‍Professor Bowen Li, at the Leslie Dan Faculty of Pharmacy and cross-appointed to the Institute of Biomedical Engineering, is the recipient of an Accelerate Translation grant to support his project “Self-Driving LNP Discovery Lab: An AI and Robotics-Powered Platform Facilitating mRNA Therapy Delivery.”

“This suite of Acceleration Grants is an excellent example of how the Acceleration Consortium is advancing the globally recognized strategic research mission of the University of Toronto in a way that’s critical for Canada to remain competitive on the international stage,” says Leah Cowen, U of T’s vice-president of research and innovation, and strategic initiatives.

“By enabling the next generation of scientists to use self-driving labs and fostering research collaboration and partnerships between departments and institutions, these grants will enable the recipients to conduct high-impact, interdisciplinary accelerated research to discover materials that will improve our world.

“I congratulate the principal investigators and their teams who are leading these varied investigations, and I look forward to seeing their results in the accelerated timeline now made possible in part by CFREF and the remarkable demonstration of support for their work.”

While the CFREF funding will help to further advancements made by several researchers who are recognized as leaders in their fields, most support is going to early-career scientists who are pioneering new discoveries just as SDL technology is emerging as a revolutionary approach to knowledge. Projects dedicated to the continuous improvement of SDL technology are also being funded. As an example, Vijaykumar’s project will develop software that can better manage the fast-flowing data streams SDLs create as well as the resources required to run the experiments.

“The work our grant recipients are doing will help us ensure that the Greater Toronto Area and Canada remain world leaders in AI-frontier discovery,” says Aspuru-Guzik.

“And we’re doing so with innovative contributions from people at every stage of their career, with an eye to developing the next generation of groundbreaking researchers along the way. No one is resting on their laurels; each grant recipient and member of the AC is pushing the edge of what is possible and is working towards a materially better future.”

The Acceleration Consortium opens its next funding competition in summer 2024 to welcome proposals for new research projects.

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Ottawa orders TikTok’s Canadian arm to be dissolved

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The federal government is ordering the dissolution of TikTok’s Canadian business after a national security review of the Chinese company behind the social media platform, but stopped short of ordering people to stay off the app.

Industry Minister François-Philippe Champagne announced the government’s “wind up” demand Wednesday, saying it is meant to address “risks” related to ByteDance Ltd.’s establishment of TikTok Technology Canada Inc.

“The decision was based on the information and evidence collected over the course of the review and on the advice of Canada’s security and intelligence community and other government partners,” he said in a statement.

The announcement added that the government is not blocking Canadians’ access to the TikTok application or their ability to create content.

However, it urged people to “adopt good cybersecurity practices and assess the possible risks of using social media platforms and applications, including how their information is likely to be protected, managed, used and shared by foreign actors, as well as to be aware of which country’s laws apply.”

Champagne’s office did not immediately respond to a request for comment seeking details about what evidence led to the government’s dissolution demand, how long ByteDance has to comply and why the app is not being banned.

A TikTok spokesperson said in a statement that the shutdown of its Canadian offices will mean the loss of hundreds of well-paying local jobs.

“We will challenge this order in court,” the spokesperson said.

“The TikTok platform will remain available for creators to find an audience, explore new interests and for businesses to thrive.”

The federal Liberals ordered a national security review of TikTok in September 2023, but it was not public knowledge until The Canadian Press reported in March that it was investigating the company.

At the time, it said the review was based on the expansion of a business, which it said constituted the establishment of a new Canadian entity. It declined to provide any further details about what expansion it was reviewing.

A government database showed a notification of new business from TikTok in June 2023. It said Network Sense Ventures Ltd. in Toronto and Vancouver would engage in “marketing, advertising, and content/creator development activities in relation to the use of the TikTok app in Canada.”

Even before the review, ByteDance and TikTok were lightning rod for privacy and safety concerns because Chinese national security laws compel organizations in the country to assist with intelligence gathering.

Such concerns led the U.S. House of Representatives to pass a bill in March designed to ban TikTok unless its China-based owner sells its stake in the business.

Champagne’s office has maintained Canada’s review was not related to the U.S. bill, which has yet to pass.

Canada’s review was carried out through the Investment Canada Act, which allows the government to investigate any foreign investment with potential to might harm national security.

While cabinet can make investors sell parts of the business or shares, Champagne has said the act doesn’t allow him to disclose details of the review.

Wednesday’s dissolution order was made in accordance with the act.

The federal government banned TikTok from its mobile devices in February 2023 following the launch of an investigation into the company by federal and provincial privacy commissioners.

— With files from Anja Karadeglija in Ottawa

This report by The Canadian Press was first published Nov. 6, 2024.

The Canadian Press. All rights reserved.

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Here is how to prepare your online accounts for when you die

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LONDON (AP) — Most people have accumulated a pile of data — selfies, emails, videos and more — on their social media and digital accounts over their lifetimes. What happens to it when we die?

It’s wise to draft a will spelling out who inherits your physical assets after you’re gone, but don’t forget to take care of your digital estate too. Friends and family might treasure files and posts you’ve left behind, but they could get lost in digital purgatory after you pass away unless you take some simple steps.

Here’s how you can prepare your digital life for your survivors:

Apple

The iPhone maker lets you nominate a “ legacy contact ” who can access your Apple account’s data after you die. The company says it’s a secure way to give trusted people access to photos, files and messages. To set it up you’ll need an Apple device with a fairly recent operating system — iPhones and iPads need iOS or iPadOS 15.2 and MacBooks needs macOS Monterey 12.1.

For iPhones, go to settings, tap Sign-in & Security and then Legacy Contact. You can name one or more people, and they don’t need an Apple ID or device.

You’ll have to share an access key with your contact. It can be a digital version sent electronically, or you can print a copy or save it as a screenshot or PDF.

Take note that there are some types of files you won’t be able to pass on — including digital rights-protected music, movies and passwords stored in Apple’s password manager. Legacy contacts can only access a deceased user’s account for three years before Apple deletes the account.

Google

Google takes a different approach with its Inactive Account Manager, which allows you to share your data with someone if it notices that you’ve stopped using your account.

When setting it up, you need to decide how long Google should wait — from three to 18 months — before considering your account inactive. Once that time is up, Google can notify up to 10 people.

You can write a message informing them you’ve stopped using the account, and, optionally, include a link to download your data. You can choose what types of data they can access — including emails, photos, calendar entries and YouTube videos.

There’s also an option to automatically delete your account after three months of inactivity, so your contacts will have to download any data before that deadline.

Facebook and Instagram

Some social media platforms can preserve accounts for people who have died so that friends and family can honor their memories.

When users of Facebook or Instagram die, parent company Meta says it can memorialize the account if it gets a “valid request” from a friend or family member. Requests can be submitted through an online form.

The social media company strongly recommends Facebook users add a legacy contact to look after their memorial accounts. Legacy contacts can do things like respond to new friend requests and update pinned posts, but they can’t read private messages or remove or alter previous posts. You can only choose one person, who also has to have a Facebook account.

You can also ask Facebook or Instagram to delete a deceased user’s account if you’re a close family member or an executor. You’ll need to send in documents like a death certificate.

TikTok

The video-sharing platform says that if a user has died, people can submit a request to memorialize the account through the settings menu. Go to the Report a Problem section, then Account and profile, then Manage account, where you can report a deceased user.

Once an account has been memorialized, it will be labeled “Remembering.” No one will be able to log into the account, which prevents anyone from editing the profile or using the account to post new content or send messages.

X

It’s not possible to nominate a legacy contact on Elon Musk’s social media site. But family members or an authorized person can submit a request to deactivate a deceased user’s account.

Passwords

Besides the major online services, you’ll probably have dozens if not hundreds of other digital accounts that your survivors might need to access. You could just write all your login credentials down in a notebook and put it somewhere safe. But making a physical copy presents its own vulnerabilities. What if you lose track of it? What if someone finds it?

Instead, consider a password manager that has an emergency access feature. Password managers are digital vaults that you can use to store all your credentials. Some, like Keeper,Bitwarden and NordPass, allow users to nominate one or more trusted contacts who can access their keys in case of an emergency such as a death.

But there are a few catches: Those contacts also need to use the same password manager and you might have to pay for the service.

___

Is there a tech challenge you need help figuring out? Write to us at onetechtip@ap.org with your questions.

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Google’s partnership with AI startup Anthropic faces a UK competition investigation

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LONDON (AP) — Britain’s competition watchdog said Thursday it’s opening a formal investigation into Google’s partnership with artificial intelligence startup Anthropic.

The Competition and Markets Authority said it has “sufficient information” to launch an initial probe after it sought input earlier this year on whether the deal would stifle competition.

The CMA has until Dec. 19 to decide whether to approve the deal or escalate its investigation.

“Google is committed to building the most open and innovative AI ecosystem in the world,” the company said. “Anthropic is free to use multiple cloud providers and does, and we don’t demand exclusive tech rights.”

San Francisco-based Anthropic was founded in 2021 by siblings Dario and Daniela Amodei, who previously worked at ChatGPT maker OpenAI. The company has focused on increasing the safety and reliability of AI models. Google reportedly agreed last year to make a multibillion-dollar investment in Anthropic, which has a popular chatbot named Claude.

Anthropic said it’s cooperating with the regulator and will provide “the complete picture about Google’s investment and our commercial collaboration.”

“We are an independent company and none of our strategic partnerships or investor relationships diminish the independence of our corporate governance or our freedom to partner with others,” it said in a statement.

The U.K. regulator has been scrutinizing a raft of AI deals as investment money floods into the industry to capitalize on the artificial intelligence boom. Last month it cleared Anthropic’s $4 billion deal with Amazon and it has also signed off on Microsoft’s deals with two other AI startups, Inflection and Mistral.

The Canadian Press. All rights reserved.

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