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Approved COVID-19 vaccines not enough to inoculate all Canadians by September: Anand – Medicine Hat News

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By Mia Rabson, The Canadian Press on January 8, 2021.

Dr. Supriya Sharma, chief medical adviser at Health Canada, speaks during a press conference to announce that Health Canada has authorized the Moderna COVID-19 vaccine, at the Sir John A. Macdonald Building in Ottawa on Wednesday, Dec. 23, 2020. THE CANADIAN PRESS/David Kawai

OTTAWA – Federal procurement minister Anita Anand says Canada will do “whatever it takes” to get more vaccine doses delivered to Canada faster but there hasn’t yet been any change to the number of doses Canada is expecting to receive this winter and approvals for additional vaccines are still at least several weeks away.

Anand said Canada had already put a number of offers on the table to vaccine makers to get more deliveries faster, including upping the price per dose.

“We convey to the vaccine suppliers that we will do whatever it takes to get vaccines into this country and to do so as early as possible,” Anand said at a regular pandemic briefing to Canadians Friday.

Canada has approved two vaccines and is currently scheduled to receive four million doses from Pfizer-BioNTech and another two million from Moderna before the end of March. That is the same delivery plan that has existed since November.

Reports say Israel – which signed a contract with Pfizer in mid-November, more than three months after Canada did – paid twice as much per dose, and is getting that vaccine much faster. Israel has vaccinated more than 1.5 million people already, mostly with Pfizer-BioNTech’s vaccine.

Canada has given doses to fewer than 250,000 people.

Canada’s contracts with vaccine makers have not yet been made public but Anand said Friday Canada paid fair market value for the doses.

Reports have put the European price for Pfizer’s product somewhere between C$18 and C$24 and the United States’s at about C$25.

Moderna has previously said it is charging CDN $40 to $47 per dose.

Anand did not elaborate much on what else Canada is doing to urge faster deliveries of the hottest commodities in the world, other than to suggest Canada isn’t going to follow the United Kingdom and delay a second dose of the vaccines in a bid to get more people a first dose faster.

“It’s important from a procurement perspective to remember also, that as we press for additional deliveries on an accelerated basis, we need to be able to show to the vaccine companies that Canada is indeed following the instructions that a second dose be administered in a certain time frame,” said Anand.

Pfizer-BioNTech’s vaccine is to be given in two doses 21 days apart and Moderna’s in two doses 28 days apart.

Canada’s national advisory committee on immunization is looking at the evidence to determine if a first dose works well enough for long enough to allow the second dose to be delayed.

Neither Pfizer nor Moderna is on board with the idea, because their clinical trials are based on the dosing schedule as listed.

Dr. Supriya Sharma, the chief medical adviser at Health Canada overseeing the vaccine approvals, said there have been some calculations that suggest both vaccines are quite effective after one dose, but because almost all the trial patients who were vaccinated got a second dose on schedule, it’s impossible to know how long that single dose’s immunity would have lasted.

Sharma said early studies on animals that got single doses showed immunity waned.

She said the first report on adverse events from vaccines administered in Canada so far shows no evidence of any trouble. There have been no rare side-effects seen at all, and the mild and moderate side-effects, such as fevers, headache and fatigue, were in line, both in severity and frequency, as what was seen during the clinical trials.

That news was overshadowed by federal-provincial vaccine bickering, with Ottawa concerned doses aren’t being given by provinces fast enough and provinces arguing they’re running out of doses to give.

Several premiers say they can vaccinate people faster if more doses can be delivered and are potentially going to run out of doses.

But Anand said Ottawa has been clear to the provinces on the delivery schedules and they should base their vaccine efforts on that.

She said deliveries will double between January and February.

Moderna deliveries come every three weeks, and are to go from 170,000 per shipment to 250,000 in February and 1.24 million in March.

Pfizer deliveries happen weekly, and are to include 208,650 each week in January, and more than 366,000 each week in February. Pfizer’s March deliveries aren’t yet confirmed.

Canada expects to vaccinate three million people by the end of March, 15 million to 19 million people by the end of June, and all 38 million Canadians by the end of September.

That assumes every Canadian wishes to be immunized and that vaccines prove safe and effective for children as well as adults.

Anand acknowledged the schedule also depends on Canada approving more vaccines. Moderna and Pfizer are to send enough to vaccinate about 30 million Canadians by the end of September.

Health Canada is reviewing submissions from drugmakers AstraZeneca and Johnson & Johnson, but Sharma said a lot of information has to come in from them before decisions can be made on their vaccine candidates.

AstraZeneca’s has been approved in the United Kingdom but Canada is waiting for results from a big trial in the United States. Sharma said that review is complicated because AstraZeneca made a mistake in its earlier trials and some people only got half doses instead of full doses.

Sharma said she expects results from the AstraZeneca U.S. trial in one to three months. Johnson & Johnson could report results before the end of January.

Health Canada can’t make a decision on either until those results come in.

This report by The Canadian Press was first published Jan. 8, 2021.

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Older patients, non-English speakers more likely to be harmed in hospital: report

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Patients who are older, don’t speak English, and don’t have a high school education are more likely to experience harm during a hospital stay in Canada, according to new research.

The Canadian Institute for Health Information measured preventableharmful events from 2023 to 2024, such as bed sores and medication errors,experienced by patients who received acute care in hospital.

The research published Thursday shows patients who don’t speak English or French are 30 per cent more likely to experience harm. Patients without a high school education are 20 per cent more likely to endure harm compared to those with higher education levels.

The report also found that patients 85 and older are five times more likely to experience harm during a hospital stay compared to those under 20.

“The goal of this report is to get folks thinking about equity as being a key dimension of the patient safety effort within a hospital,” says Dana Riley, an author of the report and a program lead on CIHI’s population health team.

When a health-care provider and a patient don’t speak the same language, that can result in the administration of a wrong test or procedure, research shows. Similarly, Riley says a lower level of education is associated with a lower level of health literacy, which can result in increased vulnerability to communication errors.

“It’s fairly costly to the patient and it’s costly to the system,” says Riley, noting the average hospital stay for a patient who experiences harm is four times more expensive than the cost of a hospital stay without a harmful event – $42,558 compared to $9,072.

“I think there are a variety of different reasons why we might start to think about patient safety, think about equity, as key interconnected dimensions of health-care quality,” says Riley.

The analysis doesn’t include data on racialized patients because Riley says pan-Canadian data was not available for their research. Data from Quebec and some mental health patients was also excluded due to differences in data collection.

Efforts to reduce patient injuries at one Ontario hospital network appears to have resulted in less harm. Patient falls at Mackenzie Health causing injury are down 40 per cent, pressure injuries have decreased 51 per cent, and central line-associated bloodstream infections, such as IV therapy, have been reduced 34 per cent.

The hospital created a “zero harm” plan in 2019 to reduce errors after a hospital survey revealed low safety scores. They integrated principles used in aviation and nuclear industries, which prioritize safety in complex high-risk environments.

“The premise is first driven by a cultural shift where people feel comfortable actually calling out these events,” says Mackenzie Health President and Chief Executive Officer Altaf Stationwala.

They introduced harm reduction training and daily meetings to discuss risks in the hospital. Mackenzie partnered with virtual interpreters that speak 240 languages and understand medical jargon. Geriatric care nurses serve the nearly 70 per cent of patients over the age of 75, and staff are encouraged to communicate as frequently as possible, and in plain language, says Stationwala.

“What we do in health care is we take control away from patients and families, and what we know is we need to empower patients and families and that ultimately results in better health care.”

This report by The Canadian Press was first published Oct. 17, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

The Canadian Press. All rights reserved.

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Alberta to launch new primary care agency by next month in health overhaul

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CALGARY – Alberta’s health minister says a new agency responsible for primary health care should be up and running by next month.

Adriana LaGrange says Primary Care Alberta will work to improve Albertans’ access to primary care providers like family doctors or nurse practitioners, create new models of primary care and increase access to after-hours care through virtual means.

Her announcement comes as the provincial government continues to divide Alberta Health Services into four new agencies.

LaGrange says Alberta Health Services hasn’t been able to focus on primary health care, and has been missing system oversight.

The Alberta government’s dismantling of the health agency is expected to include two more organizations responsible for hospital care and continuing care.

Another new agency, Recovery Alberta, recently took over the mental health and addictions portfolio of Alberta Health Services.

This report by The Canadian Press was first published Oct. 15, 2024.

The Canadian Press. All rights reserved.

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Experts urge streamlined, more compassionate miscarriage care in Canada

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Rana Van Tuyl was about 12 weeks pregnant when she got devastating news at her ultrasound appointment in December 2020.

Her fetus’s heartbeat had stopped.

“We were both shattered,” says Van Tuyl, who lives in Nanaimo, B.C., with her partner. Her doctor said she could surgically or medically pass the pregnancy and she chose the medical option, a combination of two drugs taken at home.

“That was the last I heard from our maternity physician, with no further followup,” she says.

But complications followed. She bled for a month and required a surgical procedure to remove pregnancy tissue her body had retained.

Looking back, Van Tuyl says she wishes she had followup care and mental health support as the couple grieved.

Her story is not an anomaly. Miscarriages affect one in five pregnancies in Canada, yet there is often a disconnect between the medical view of early pregnancy loss as something that is easily managed and the reality of the patients’ own traumatizing experiences, according to a paper published Tuesday in the Canadian Medical Association Journal.

An accompanying editorial says it’s time to invest in early pregnancy assessment clinics that can provide proper care during and after a miscarriage, which can have devastating effects.

The editorial and a review of medical literature on early pregnancy loss say patients seeking help in emergency departments often receive “suboptimal” care. Non-critical miscarriage cases drop to the bottom of the triage list, resulting in longer wait times that make patients feel like they are “wasting” health-care providers’ time. Many of those patients are discharged without a followup plan, the editorial says.

But not all miscarriages need to be treated in the emergency room, says Dr. Modupe Tunde-Byass, one of the authors of the literature review and an obstetrician/gynecologist at Toronto’s North York General Hospital.

She says patients should be referred to early pregnancy assessment clinics, which provide compassionate care that accounts for the psychological impact of pregnancy loss – including grief, guilt, anxiety and post-traumatic stress.

But while North York General Hospital and a patchwork of other health-care providers in the country have clinics dedicated to miscarriage care, Tunde-Byass says that’s not widely adopted – and it should be.

She’s been thinking about this gap in the Canadian health-care system for a long time, ever since her medical training almost four decades ago in the United Kingdom, where she says early pregnancy assessment centres are common.

“One of the things that we did at North York was to have a clinic to provide care for our patients, and also to try to bridge that gap,” says Tunde-Byass.

Provincial agency Health Quality Ontario acknowledged in 2019 the need for these services in a list of ways to better manage early pregnancy complications and loss.

“Five years on, little if any progress has been made toward achieving this goal,” Dr. Catherine Varner, an emergency physician, wrote in the CMAJ editorial. “Early pregnancy assessment services remain a pipe dream for many, especially in rural Canada.”

The quality standard released in Ontario did, however, prompt a registered nurse to apply for funding to open an early pregnancy assessment clinic at St. Joseph’s Healthcare Hamilton in 2021.

Jessica Desjardins says that after taking patient referrals from the hospital’s emergency room, the team quickly realized that they would need a bigger space and more people to provide care. The clinic now operates five days a week.

“We’ve been often hearing from our patients that early pregnancy loss and experiencing early pregnancy complications is a really confusing, overwhelming, isolating time for them, and (it) often felt really difficult to know where to go for care and where to get comprehensive, well-rounded care,” she says.

At the Hamilton clinic, Desjardins says patients are brought into a quiet area to talk and make decisions with providers – “not only (from) a physical perspective, but also keeping in mind the psychosocial piece that comes along with loss and the grief that’s a piece of that.”

Ashley Hilliard says attending an early pregnancy assessment clinic at The Ottawa Hospital was the “best case scenario” after the worst case scenario.

In 2020, she was about eight weeks pregnant when her fetus died and she hemorrhaged after taking medication to pass the pregnancy at home.

Shortly after Hilliard was rushed to the emergency room, she was assigned an OB-GYN at an early pregnancy assessment clinic who directed and monitored her care, calling her with blood test results and sending her for ultrasounds when bleeding and cramping persisted.

“That was super helpful to have somebody to go through just that, somebody who does this all the time,” says Hilliard.

“It was really validating.”

This report by The Canadian Press was first published Oct. 15, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

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