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Being stressed out before you get COVID increases your chances of long COVID. Here’s why

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Stress is part and parcel of modern life. When we’re on the verge of a new challenge or a significant event, we can experience stress mixed with excitement and a sense of challenge. This form of “good” stress, or eustress, is important for growth, development, and achievement.

However, prolonged stress and overwhelming or traumatic events can negatively impact our health. These forms of “bad” stress—or distress—can make us sick, depressed, anxious and over the long term, increase our risk of heart disease, stroke, type 2 diabetes, dementia and even cancer.

Distress can also affect our ability to fully recover from COVID. Ongoing symptoms for a month or more is referred to as long COVID. Those affected can experience fatigue, brain fog, shortness of breath, loss of taste and smell, difficulty sleeping, anxiety and/or depression. For some, these symptoms can last for many months or even years, making it impossible to return to pre-COVID life.

In a Harvard University study published last month, people suffering in the lead up to their COVID infection had a greater chance of experiencing long COVID. The researchers found those with two types of distress (depression, probable anxiety, perceived stress, worry about COVID, and loneliness) had an almost 50% greater risk of long COVID than other participants.

So how might distress impact the body’s ability to fight infection?

First, we need to look at inflammation

Inflammation is the body’s way of responding to an infection or injury.

When the immune system encounters a virus, for example, it launches an attack to neutralize infected cells and store a memory of that virus so it can respond faster and more effectively the next time.

Many things can cause inflammation, including bacteria and viruses, injuries, toxins and .

The body has many different responses to inflammation, including redness, heat, swelling and pain. Some can occur silently within the body, without any of these typical symptoms. At other times, inflammation can mobilize energy resources to cause exhaustion and fever.

During inflammation, release substances known as inflammatory mediators. These chemical messengers cause to become wider (dilate), allowing more blood to reach injured or infected tissue to help with the healing process.

This process can also irritate nerves and cause pain signals to be sent to the brain.

What does distress have to do with inflammation?

In the short term, stress causes the release of hormones that suppress inflammation, ensuring the body has enough energy resources available to respond an immediate threat.

However, when experienced over an extended period of time, stress itself can cause low grade “silent” inflammation. Chronic distress and related mental health conditions such as anxiety and depression, are all associated with elevated levels of inflammatory mediators. In fact, the repeated exposure to mild, unpredictable stress is enough to elicit an inflammatory response.

Pre-clinical (lab-based) studies have shown chronic mild stress can cause depression-like behavior by promoting inflammation, including activating immune cells in the brain (microglia). When anti-inflammatories were given during the mild stress exposure they prevented depression-like behavior. However if given after the event, the anti-inflammatories were ineffective.

When inflammation is ongoing, such as with extended periods of distress, the changes the way it responds by reprogramming the immune cells. Effectively, it switches to “low surveillance mode.” In this way, it remains active throughout the body, but downgrades its responsiveness to new threats.

Because of this, the response may be slower and less effective. Consequently, the process of recovery can take longer. For a virus like COVID, it’s possible that prior exposure to distress may similarly impair the body’s ability to fight the infection and increase the risk of long COVID.

How might distress affect recovery from COVID?

There is still much to learn about how COVID infection affects the body and how psychological factors can impact clinical outcomes in the short and long term.

COVID has far-reaching effects across multiple body systems, affecting the lungs and heart to the greatest degree, and increasing the risk of blood clotting and stroke.

Because the virus resides within human cells, an immune system switched to “low surveillance mode” as a result of psychological distress may miss early opportunities to destroy infected tissues. The virus can then gain an advantage over the defense (immune) system.

Conversely, distress can suppress the early response, tipping the balance in favor of the invader.

So what can we do about it?

Vaccines work by helping to train the immune system to find the target sooner, giving the immune system the advantage.

Behavioral interventions that improve the ability to cope with stress decrease inflammation and may help to enhance the immune response to COVID.

It’s also important to be aware that exposure to COVID increases the risk of depression, anxiety or other mental health conditions. Knowledge of this two-directional link is the first critical step to improving clinical outcomes.

A lifestyle medicine approach that helps to reduce levels of distress and address mental health symptoms has important downstream benefits for physical health. This is likely to not only be the result of direct effects on the immune system itself, but also through related improvements in health behaviors such as diet, exercise and/or sleep.

Further research is needed to better understand the impact of on the immune system, mental health and COVID outcomes, and to highlight ways to intervene to prevent long COVID and support recovery.


 

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Being stressed out before you get COVID increases your chances of long COVID. Here’s why (2022, October 19)
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What’s the greatest holiday gift: lips, hair, skin? Give the gift of great skin this holiday season

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Give the gift of great skin this holiday season

Skinstitut Holiday Gift Kits take the stress out of gifting

Toronto, October 31, 2024 – Beauty gifts are at the top of holiday wish lists this year, and Laser Clinics Canada, a leader in advanced beauty treatments and skincare, is taking the pressure out of seasonal shopping. Today, Laser Clincs Canada announces the arrival of its 2024 Holiday Gift Kits, courtesy of Skinstitut, the exclusive skincare line of Laser Clinics Group.

In time for the busy shopping season, the limited-edition Holiday Gifts Kits are available in Laser Clinics locations in the GTA and Ottawa. Clinics are conveniently located in popular shopping centers, including Hillcrest Mall, Square One, CF Sherway Gardens, Scarborough Town Centre, Rideau Centre, Union Station and CF Markville. These limited-edition Kits are available on a first come, first served basis.

“These kits combine our best-selling products, bundled to address the most relevant skin concerns we’re seeing among our clients,” says Christina Ho, Senior Brand & LAM Manager at Laser Clinics Canada. “With several price points available, the kits offer excellent value and suit a variety of gift-giving needs, from those new to cosmeceuticals to those looking to level up their skincare routine. What’s more, these kits are priced with a savings of up to 33 per cent so gift givers can save during the holiday season.

There are two kits to select from, each designed to address key skin concerns and each with a unique theme — Brightening Basics and Hydration Heroes.

Brightening Basics is a mix of everyday essentials for glowing skin for all skin types. The bundle comes in a sleek pink, reusable case and includes three full-sized products: 200ml gentle cleanser, 50ml Moisture Defence (normal skin) and 30ml1% Hyaluronic Complex Serum. The Brightening Basics kit is available at $129, a saving of 33 per cent.

Hydration Heroes is a mix of hydration essentials and active heroes that cater to a wide variety of clients. A perfect stocking stuffer, this bundle includes four deluxe products: Moisture 15 15 ml Defence for normal skin, 10 ml 1% Hyaluronic Complex Serum, 10 ml Retinol Serum and 50 ml Expert Squalane Cleansing Oil. The kit retails at $59.

In addition to the 2024 Holiday Gifts Kits, gift givers can easily add a Laser Clinic Canada gift card to the mix. Offering flexibility, recipients can choose from a wide range of treatments offered by Laser Clinics Canada, or they can expand their collection of exclusive Skinstitut products.

 

Brightening Basics 2024 Holiday Gift Kit by Skinstitut, available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

Hydration Heroes 2024 Holiday Gift Kit by Skinstitut – available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

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Here is how to prepare your online accounts for when you die

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LONDON (AP) — Most people have accumulated a pile of data — selfies, emails, videos and more — on their social media and digital accounts over their lifetimes. What happens to it when we die?

It’s wise to draft a will spelling out who inherits your physical assets after you’re gone, but don’t forget to take care of your digital estate too. Friends and family might treasure files and posts you’ve left behind, but they could get lost in digital purgatory after you pass away unless you take some simple steps.

Here’s how you can prepare your digital life for your survivors:

Apple

The iPhone maker lets you nominate a “ legacy contact ” who can access your Apple account’s data after you die. The company says it’s a secure way to give trusted people access to photos, files and messages. To set it up you’ll need an Apple device with a fairly recent operating system — iPhones and iPads need iOS or iPadOS 15.2 and MacBooks needs macOS Monterey 12.1.

For iPhones, go to settings, tap Sign-in & Security and then Legacy Contact. You can name one or more people, and they don’t need an Apple ID or device.

You’ll have to share an access key with your contact. It can be a digital version sent electronically, or you can print a copy or save it as a screenshot or PDF.

Take note that there are some types of files you won’t be able to pass on — including digital rights-protected music, movies and passwords stored in Apple’s password manager. Legacy contacts can only access a deceased user’s account for three years before Apple deletes the account.

Google

Google takes a different approach with its Inactive Account Manager, which allows you to share your data with someone if it notices that you’ve stopped using your account.

When setting it up, you need to decide how long Google should wait — from three to 18 months — before considering your account inactive. Once that time is up, Google can notify up to 10 people.

You can write a message informing them you’ve stopped using the account, and, optionally, include a link to download your data. You can choose what types of data they can access — including emails, photos, calendar entries and YouTube videos.

There’s also an option to automatically delete your account after three months of inactivity, so your contacts will have to download any data before that deadline.

Facebook and Instagram

Some social media platforms can preserve accounts for people who have died so that friends and family can honor their memories.

When users of Facebook or Instagram die, parent company Meta says it can memorialize the account if it gets a “valid request” from a friend or family member. Requests can be submitted through an online form.

The social media company strongly recommends Facebook users add a legacy contact to look after their memorial accounts. Legacy contacts can do things like respond to new friend requests and update pinned posts, but they can’t read private messages or remove or alter previous posts. You can only choose one person, who also has to have a Facebook account.

You can also ask Facebook or Instagram to delete a deceased user’s account if you’re a close family member or an executor. You’ll need to send in documents like a death certificate.

TikTok

The video-sharing platform says that if a user has died, people can submit a request to memorialize the account through the settings menu. Go to the Report a Problem section, then Account and profile, then Manage account, where you can report a deceased user.

Once an account has been memorialized, it will be labeled “Remembering.” No one will be able to log into the account, which prevents anyone from editing the profile or using the account to post new content or send messages.

X

It’s not possible to nominate a legacy contact on Elon Musk’s social media site. But family members or an authorized person can submit a request to deactivate a deceased user’s account.

Passwords

Besides the major online services, you’ll probably have dozens if not hundreds of other digital accounts that your survivors might need to access. You could just write all your login credentials down in a notebook and put it somewhere safe. But making a physical copy presents its own vulnerabilities. What if you lose track of it? What if someone finds it?

Instead, consider a password manager that has an emergency access feature. Password managers are digital vaults that you can use to store all your credentials. Some, like Keeper,Bitwarden and NordPass, allow users to nominate one or more trusted contacts who can access their keys in case of an emergency such as a death.

But there are a few catches: Those contacts also need to use the same password manager and you might have to pay for the service.

___

Is there a tech challenge you need help figuring out? Write to us at onetechtip@ap.org with your questions.

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Pediatric group says doctors should regularly screen kids for reading difficulties

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The Canadian Paediatric Society says doctors should regularly screen children for reading difficulties and dyslexia, calling low literacy a “serious public health concern” that can increase the risk of other problems including anxiety, low self-esteem and behavioural issues, with lifelong consequences.

New guidance issued Wednesday says family doctors, nurses, pediatricians and other medical professionals who care for school-aged kids are in a unique position to help struggling readers access educational and specialty supports, noting that identifying problems early couldhelp kids sooner — when it’s more effective — as well as reveal other possible learning or developmental issues.

The 10 recommendations include regular screening for kids aged four to seven, especially if they belong to groups at higher risk of low literacy, including newcomers to Canada, racialized Canadians and Indigenous Peoples. The society says this can be done in a two-to-three-minute office-based assessment.

Other tips encourage doctors to look for conditions often seen among poor readers such as attention-deficit hyperactivity disorder; to advocate for early literacy training for pediatric and family medicine residents; to liaise with schools on behalf of families seeking help; and to push provincial and territorial education ministries to integrate evidence-based phonics instruction into curriculums, starting in kindergarten.

Dr. Scott McLeod, one of the authors and chair of the society’s mental health and developmental disabilities committee, said a key goal is to catch kids who may be falling through the cracks and to better connect families to resources, including quicker targeted help from schools.

“Collaboration in this area is so key because we need to move away from the silos of: everything educational must exist within the educational portfolio,” McLeod said in an interview from Calgary, where he is a developmental pediatrician at Alberta Children’s Hospital.

“Reading, yes, it’s education, but it’s also health because we know that literacy impacts health. So I think that a statement like this opens the window to say: Yes, parents can come to their health-care provider to get advice, get recommendations, hopefully start a collaboration with school teachers.”

McLeod noted that pediatricians already look for signs of low literacy in young children by way of a commonly used tool known as the Rourke Baby Record, which offers a checklist of key topics, such as nutrition and developmental benchmarks, to cover in a well-child appointment.

But he said questions about reading could be “a standing item” in checkups and he hoped the society’s statement to medical professionals who care for children “enhances their confidence in being a strong advocate for the child” while spurring partnerships with others involved in a child’s life such as teachers and psychologists.

The guidance said pediatricians also play a key role in detecting and monitoring conditions that often coexist with difficulty reading such as attention-deficit hyperactivity disorder, but McLeod noted that getting such specific diagnoses typically involves a referral to a specialist, during which time a child continues to struggle.

He also acknowledged that some schools can be slow to act without a specific diagnosis from a specialist, and even then a child may end up on a wait list for school interventions.

“Evidence-based reading instruction shouldn’t have to wait for some of that access to specialized assessments to occur,” he said.

“My hope is that (by) having an existing statement or document written by the Canadian Paediatric Society … we’re able to skip a few steps or have some of the early interventions present,” he said.

McLeod added that obtaining specific assessments from medical specialists is “definitely beneficial and advantageous” to know where a child is at, “but having that sort of clear, thorough assessment shouldn’t be a barrier to intervention starting.”

McLeod said the society was partly spurred to act by 2022’s “Right to Read Inquiry Report” from the Ontario Human Rights Commission, which made 157 recommendations to address inequities related to reading instruction in that province.

He called the new guidelines “a big reminder” to pediatric providers, family doctors, school teachers and psychologists of the importance of literacy.

“Early identification of reading difficulty can truly change the trajectory of a child’s life.”

This report by The Canadian Press was first published Oct. 23, 2024.

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