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Canada's COVAX program use draws criticism for unequal vaccine distribution – Yahoo News Canada

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The Canadian Press

‘New chance at life’: Man gets face, hands in rare surgery

NEW YORK — Almost six months after a rare face and hands transplant, Joe DiMeo is relearning how to smile, blink, pinch and squeeze. The 22-year-old New Jersey resident had the operation last August, two years after being badly burned in a car crash. “I knew it would be baby steps all the way,” DiMeo told The Associated Press recently. “You’ve got to have a lot of motivation, a lot of patience. And you’ve got to stay strong through everything.” Experts say it appears the surgery at NYU Langone Health was a success, but warn it’ll take some time to say for sure. Worldwide, surgeons have completed at least 18 face transplants and 35 hand transplants, according to the United Network for Organ Sharing, or UNOS, which oversees the U.S. transplant system. But simultaneous face and double hand transplants are extremely rare and have only been tried twice before. The first attempt was in 2009 on a patient in Paris who died about a month later from complications. Two years later, Boston doctors tried it again on a woman who was mauled by a chimpanzee, but ultimately had to remove the transplanted hands days later. “The fact they could pull it off is phenomenal,” said Dr. Bohdan Pomahac, a surgeon at Boston’s Brigham and Women’s Hospital who led the second such attempt. “I know firsthand it’s incredibly complicated. It’s a tremendous success.” DiMeo will be on lifelong medications to avoid rejecting the transplants, as well as continued rehabilitation to gain sensation and function in his new face and hands. In 2018, DiMeo fell asleep at the wheel, he said, after working a night shift as a product tester for a drug company. The car hit a curb and utility pole, flipped over, and burst into flames. Another driver who saw the accident pulled over to rescue DiMeo. Afterward, he spent months in a medically induced coma and underwent 20 reconstructive surgeries and multiple skin grafts to treat his extensive third-degree burns. Once it became clear conventional surgeries could not help him regain full vision or use of his hands, DiMeo’s medical team began preparing for the risky transplant in early 2019. “Within the world of transplantation, they’re probably the most unusual,” said Dr. David Klassen, UNOS chief medical officer. Almost immediately, the NYU team encountered challenges including finding a donor. Doctors estimated he only had a 6% chance of finding a match compatible with his immune system. They also wanted to find someone with the same gender, skin tone and hand dominance. Then during the search for a donor, the pandemic hit and organ donations plummeted. During New York City’s surge, members of the transplant unit were reassigned to work in COVID-19 wards. In early August, the team finally identified a donor in Delaware and completed the 23-hour procedure a few days later. They amputated both of DiMeo’s hands, replacing them mid-forearm and connecting nerves, blood vessels and 21 tendons with hair-thin sutures. They also transplanted a full face, including the forehead, eyebrows, nose, eyelids, lips, both ears and underlying facial bones. “The possibility of us being successful based on the track record looked slim,” said Dr. Eduardo Rodriguez, who led the medical team of more than 140 people. “It’s not that someone has done this many times before and we have a kind of a schedule, a recipe to follow.” So far, DiMeo has not shown any signs of rejecting his new face or hands, said Rodriguez. Since leaving the hospital in November, DiMeo has been in intensive rehabilitation, devoting hours daily to physical, occupational and speech therapy. “Rehab was pretty intense,” DiMeo said, and involves a lot of “retraining yourself to do stuff on your own again.” During a recent session, he practiced raising his eyebrows, opening and closing his eyes, puckering his mouth, giving a thumbs up and whistling. DiMeo can feel his new forehead and hands get cold, and often reaches up to push his long hair off of his face. DiMeo, who lives with his parents, can now dress and feed himself. He shoots pool and plays with his dog Buster. Once an avid gym-goer, DiMeo is also working out again — benching 50 pounds and practicing his golf swing. “You got a new chance at life. You really can’t give up,” he said. As with any transplant, the danger of rejection is highest early on, but lasts indefinitely. The medications he takes also leave him vulnerable, for the rest of his life, to infections. “You’re never free from that risk,” Klassen said. “Transplantation for any patient is a process that plays out over a long period of time.” Still, Rodriguez said he’s amazed to see that DiMeo has been able to master skills like zipping up his jacket and putting on his shoes. “It’s very gratifying to all of us,” Rodriguez said. “There’s a tremendous sense of pride.” ___ Follow Marion Renault on Twitter: @MarionRenault ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. Marion Renault And Marshall Ritzel, The Associated Press

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Roots sees room for expansion in activewear, reports $5.2M Q2 loss and sales drop

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TORONTO – Roots Corp. may have built its brand on all things comfy and cosy, but its CEO says activewear is now “really becoming a core part” of the brand.

The category, which at Roots spans leggings, tracksuits, sports bras and bike shorts, has seen such sustained double-digit growth that Meghan Roach plans to make it a key part of the business’ future.

“It’s an area … you will see us continue to expand upon,” she told analysts on a Friday call.

The Toronto-based retailer’s push into activewear has taken shape over many years and included several turns as the official designer and supplier of Team Canada’s Olympic uniform.

But consumers have had plenty of choice when it comes to workout gear and other apparel suited to their sporting needs. On top of the slew of athletic brands like Nike and Adidas, shoppers have also gravitated toward Lululemon Athletica Inc., Alo and Vuori, ramping up competition in the activewear category.

Roach feels Roots’ toehold in the category stems from the fit, feel and following its merchandise has cultivated.

“Our product really resonates with (shoppers) because you can wear it through multiple different use cases and occasions,” she said.

“We’ve been seeing customers come back again and again for some of these core products in our activewear collection.”

Her remarks came the same day as Roots revealed it lost $5.2 million in its latest quarter compared with a loss of $5.3 million in the same quarter last year.

The company said the second-quarter loss amounted to 13 cents per diluted share for the quarter ended Aug. 3, the same as a year earlier.

In presenting the results, Roach reminded analysts that the first half of the year is usually “seasonally small,” representing just 30 per cent of the company’s annual sales.

Sales for the second quarter totalled $47.7 million, down from $49.4 million in the same quarter last year.

The move lower came as direct-to-consumer sales amounted to $36.4 million, down from $37.1 million a year earlier, as comparable sales edged down 0.2 per cent.

The numbers reflect the fact that Roots continued to grapple with inventory challenges in the company’s Cooper fleece line that first cropped up in its previous quarter.

Roots recently began to use artificial intelligence to assist with daily inventory replenishments and said more tools helping with allocation will go live in the next quarter.

Beyond that time period, the company intends to keep exploring AI and renovate more of its stores.

It will also re-evaluate its design ranks.

Roots announced Friday that chief product officer Karuna Scheinfeld has stepped down.

Rather than fill the role, the company plans to hire senior level design talent with international experience in the outdoor and activewear sectors who will take on tasks previously done by the chief product officer.

This report by The Canadian Press was first published Sept. 13, 2024.

Companies in this story: (TSX:ROOT)

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Talks on today over HandyDART strike affecting vulnerable people in Metro Vancouver

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VANCOUVER – Mediated talks between the union representing HandyDART workers in Metro Vancouver and its employer, Transdev, are set to resume today as a strike that has stopped most services drags into a second week.

No timeline has been set for the length of the negotiations, but Joe McCann, president of the Amalgamated Transit Union Local 1724, says they are willing to stay there as long as it takes, even if talks drag on all night.

About 600 employees of the door-to-door transit service for people unable to navigate the conventional transit system have been on strike since last Tuesday, pausing service for all but essential medical trips.

Hundreds of drivers rallied outside TransLink’s head office earlier this week, calling for the transportation provider to intervene in the dispute with Transdev, which was contracted to oversee HandyDART service.

Transdev said earlier this week that it will provide a reply to the union’s latest proposal on Thursday.

A statement from the company said it “strongly believes” that their employees deserve fair wages, and that a fair contract “must balance the needs of their employees, clients and taxpayers.”

This report by The Canadian Press was first published Sept. 12, 2024.

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Transat AT reports $39.9M Q3 loss compared with $57.3M profit a year earlier

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MONTREAL – Travel company Transat AT Inc. reported a loss in its latest quarter compared with a profit a year earlier as its revenue edged lower.

The parent company of Air Transat says it lost $39.9 million or $1.03 per diluted share in its quarter ended July 31.

The result compared with a profit of $57.3 million or $1.49 per diluted share a year earlier.

Revenue in what was the company’s third quarter totalled $736.2 million, down from $746.3 million in the same quarter last year.

On an adjusted basis, Transat says it lost $1.10 per share in its latest quarter compared with an adjusted profit of $1.10 per share a year earlier.

Transat chief executive Annick Guérard says demand for leisure travel remains healthy, as evidenced by higher traffic, but consumers are increasingly price conscious given the current economic uncertainty.

This report by The Canadian Press was first published Sept. 12, 2024.

Companies in this story: (TSX:TRZ)

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