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Canada’s top doctor ‘optimistic’ after Canada-China vaccine partnership collapses – Global News

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In the aftermath of the collapse of a multimillion-dollar coronavirus vaccine collaboration between Canada and China, Canada’s chief public health officer says she is optimistic about advance purchase deals made recently with the American producers of two front-running vaccine candidates.

This week Canada’s National Research Council (NRC) announced it has abandoned its partnership with Chinese company CanSino Biologics because China’s government continues to block shipments of vaccine materials to Canada. If Canada had received CanSino’s vaccine this summer and confirmed its safety and effectiveness in testing, Canadians would have been front-of-line for a guaranteed supply of the vaccine, produced in NRC facilities.

But Canadian scientists and a former Canadian official responsible for vaccine collaborations with China told Global News it appears Chinese officials have blocked CanSino material because of Beijing’s geopolitical objectives.

Read more:
China blamed for Canada’s multimillion-dollar coronavirus vaccine deal collapse

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At a COVID-19 response briefing Friday, chief public health officer Teresa Tam said she is “optimistic” despite the CanSino collapse and Canada is “continuing to pursue all (potential vaccine supply) avenues internationally and domestically.”

Earlier this month, the Canadian government signed new deals with pharmaceutical firms Pfizer and Moderna to secure millions of doses in 2021 of the coronavirus vaccine candidates each company is currently developing.






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How close are we to developing a coronavirus vaccine?


How close are we to developing a coronavirus vaccine?

Tam said there are over 100 vaccine candidates in testing worldwide and Pfizer and Moderna are in the group of about 10 going through Phase 3 clinical testing.

“I was heartened with the results for older adults in the Moderna vaccine [testing],” Tam said. “But you might not expect this vaccine for quite a few months, and we may be looking at [obtaining supply of] more than one vaccine. We are keeping all of those options open.”

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Canadian vaccine researcher Gary Kobinger said the CanSino vaccine has fallen behind many candidates worldwide after its Phase 2 test results. In simple terms, the CanSino vaccine is designed to prepare immune systems to fight the coronavirus by introducing another virus — Ad5-nCoV — that encourages the production of coronavirus antibodies.

However, many elderly people have already been exposed to the virus used in the CanSino vaccine. And that means their bodies have already naturally developed defences, and won’t produce the needed coronavirus antibodies without boosted doses, Kobinger says.

“It’s a waste because it is not effective for the most important population,” Kobinger said. “There are many candidates that Canada should be betting on rather than this one.”

Meanwhile, CanSino responded Friday to reports that NRC has abandoned its partnership with China.

“Up to the date of this announcement, the collaboration between the National Research Council of Canada and the Company has not been terminated. None of the management of the Company has accepted any interview in relation to the clinical trails (sic) for Ad5-nCoV in Canada in the recent period,” a statement sent to Global News says. “The Company is currently driving the international multi-centre phase III clinical trial for Ad5-nCoV with several countries.”

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And according to the Wall Street Journal, a senior CanSino executive said the company is negotiating with several countries “to get emergency approval to use an experimental COVID-19 vaccine, developed with the Chinese military, before the completion of large-scale safety and effectiveness trials.”

“Pierre Morgon, senior vice-president for international business at CanSino, said getting the vaccine out to millions of people now, before its clinical trials are complete, would broaden the base of knowledge about the drug’s safety and effectiveness,” the Journal reported.

Morgon said several developed countries were in talks with CanSino, along with Pakistan and some Latin American countries, according to the report.

CanSino did not immediately respond to questions from Global News for this story.

And the NRC did not respond to a question from Global News on the information in the Wall Street Journal report.

Read more:
Canada-China COVID-19 vaccine trials abandoned: National Research Council

The NRC — which is part of the Ministry of Innovation, Science and Industry — has received about $44 million since late March to upgrade its production capacity in Montreal in preparation for materials expected from CanSino.

The NRC says it is working with two other COVID-19 vaccine collaborators including the United States company VBI Vaccines.

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“With the funding received from the Government of Canada on March 23 and April 23, much work is underway at NRC … to certify our facility … and expand production,” the NRC stated. “These enhancements to the facility will support a broad range of partners and clients with research, scale-up support, and the manufacturing of vaccines and therapeutics.”

© 2020 Global News, a division of Corus Entertainment Inc.

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Stop Asking Your Interviewer Cliché Questions

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Most job search advice is cookie-cutter. The advice you’re following is almost certainly the same advice other job seekers follow, making you just another candidate following the same script.

In today’s hyper-competitive job market, standing out is critical, a challenge most job seekers struggle with. Instead of relying on generic questions recommended by self-proclaimed career coaches, which often lead to a forgettable interview, ask unique, thought-provoking questions that’ll spark engaging conversations and leave a lasting impression.

English philosopher Francis Bacon once said, “A prudent question is one half of wisdom.”

The questions you ask convey the following:

  • Your level of interest in the company and the role.
  • Contributing to your employer’s success is essential.
  • You desire a cultural fit.

Here are the top four questions experts recommend candidates ask; hence, they’ve become cliché questions you should avoid asking:

  • “What are the key responsibilities of this position?”

Most likely, the job description answers this question. Therefore, asking this question indicates you didn’t read the job description. If you require clarification, ask, “How many outbound calls will I be required to make daily?” “What will be my monthly revenue target?”

  • “What does a typical day look like?”

Although it’s important to understand day-to-day expectations, this question tends to elicit vague responses and rarely leads to a deeper conversation. Don’t focus on what your day will look like; instead, focus on being clear on the results you need to deliver. Nobody I know has ever been fired for not following a “typical day.” However, I know several people who were fired for failing to meet expectations. Before accepting a job offer, ensure you’re capable of meeting the employer’s expectations.

  • “How would you describe the company culture?”

Asking this question screams, “I read somewhere to ask this question.” There are much better ways to research a company’s culture, such as speaking to current and former employees, reading online reviews and news articles. Furthermore, since your interviewer works for the company, they’re presumably comfortable with the culture. Do you expect your interviewer to give you the brutal truth? “Be careful of Craig; get on his bad side, and he’ll make your life miserable.” “Bob is close to retirement. I give him lots of slack, which the rest of the team needs to pick up.”

Truism: No matter how much due diligence you do, only when you start working for the employer will you experience and, therefore, know their culture firsthand.

  • “What opportunities are there for professional development?”

When asked this question, I immediately think the candidate cares more about gaining than contributing, a showstopper. Managing your career is your responsibility, not your employer’s.

Cliché questions don’t impress hiring managers, nor will they differentiate you from your competition. To transform your interaction with your interviewer from a Q&A session into a dynamic discussion, ask unique, insightful questions.

Here are my four go-to questions—I have many moreto accomplish this:

  • “Describe your management style. How will you manage me?”

This question gives your interviewer the opportunity to talk about themselves, which we all love doing. As well, being in sync with my boss is extremely important to me. The management style of who’ll be my boss is a determining factor in whether or not I’ll accept the job.

  • “What is the one thing I should never do that’ll piss you off and possibly damage our working relationship beyond repair?”

This question also allows me to determine whether I and my to-be boss would be in sync. Sometimes I ask, “What are your pet peeves?”

  • “When I join the team, what would be the most important contribution you’d want to see from me in the first six months?”

Setting myself up for failure is the last thing I want. As I mentioned, focus on the results you need to produce and timelines. How realistic are the expectations? It’s never about the question; it’s about what you want to know. It’s important to know whether you’ll be able to meet or even exceed your new boss’s expectations.

  • “If I wanted to sell you on an idea or suggestion, what do you need to know?”

Years ago, a candidate asked me this question. I was impressed he wasn’t looking just to put in time; he was looking for how he could be a contributing employee. Every time I ask this question, it leads to an in-depth discussion.

Other questions I’ve asked:

 

  • “What keeps you up at night?”
  • “If you were to leave this company, who would follow?”
  • “How do you handle an employee making a mistake?”
  • “If you were to give a Ted Talk, what topic would you talk about?”
  • “What are three highly valued skills at [company] that I should master to advance?”
  • “What are the informal expectations of the role?”
  • “What is one misconception people have about you [or the company]?”

 

Your questions reveal a great deal about your motivations, drive to make a meaningful impact on the business, and a chance to morph the questioning into a conversation. Cliché questions don’t lead to meaningful discussions, whereas unique, thought-provoking questions do and, in turn, make you memorable.

_____________________________________________________________________

 

Nick Kossovan, a well-seasoned veteran of the corporate landscape, offers “unsweetened” job search advice. You can send Nick your questions to artoffindingwork@gmail.com.

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Canadian Natural Resources reports $2.27-billion third-quarter profit

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CALGARY – Canadian Natural Resources Ltd. reported a third-quarter profit of $2.27 billion, down from $2.34 billion in the same quarter last year.

The company says the profit amounted to $1.06 per diluted share for the quarter that ended Sept. 30 compared with $1.06 per diluted share a year earlier.

Product sales totalled $10.40 billion, down from $11.76 billion in the same quarter last year.

Daily production for the quarter averaged 1,363,086 barrels of oil equivalent per day, down from 1,393,614 a year ago.

On an adjusted basis, Canadian Natural says it earned 97 cents per diluted share for the quarter, down from an adjusted profit of $1.30 per diluted share in the same quarter last year.

The average analyst estimate had been for a profit of 90 cents per share, according to LSEG Data & Analytics.

This report by The Canadian Press was first published Oct. 31, 2024.

Companies in this story: (TSX:CNQ)

The Canadian Press. All rights reserved.

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Cenovus Energy reports $820M Q3 profit, down from $1.86B a year ago

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CALGARY – Cenovus Energy Inc. reported its third-quarter profit fell compared with a year as its revenue edged lower.

The company says it earned $820 million or 42 cents per diluted share for the quarter ended Sept. 30, down from $1.86 billion or 97 cents per diluted share a year earlier.

Revenue for the quarter totalled $14.25 billion, down from $14.58 billion in the same quarter last year.

Total upstream production in the quarter amounted to 771,300 barrels of oil equivalent per day, down from 797,000 a year earlier.

Total downstream throughput was 642,900 barrels per day compared with 664,300 in the same quarter last year.

On an adjusted basis, Cenovus says its funds flow amounted to $1.05 per diluted share in its latest quarter, down from adjusted funds flow of $1.81 per diluted share a year earlier.

This report by The Canadian Press was first published Oct. 31, 2024.

Companies in this story: (TSX:CVE)

The Canadian Press. All rights reserved.

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