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Cancer survivors face dilemma over banned breast implants linked to rare lymphoma – CBC.ca

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Dona Murphy was finally feeling relieved. Eight years after being diagnosed with breast cancer and having a mastectomy, her oncologist declared her cancer-free.

Then in November, she received a couriered letter from the hospital where she had her surgery, delivering some shocking news: The breast implant used during her reconstruction was now banned by Health Canada.

Last May, Health Canada pulled a type of textured breast implant off the market, following a joint investigation by CBC News, Radio-Canada, the Toronto Star and the Washington-based International Consortium of Investigative Journalists.

The product — specifically macro-textured Biocell implants, made by Allergan — has been linked to a rare form of lymphoma known as breast-implant-associated anaplastic large cell lymphoma, or BIA-ALCL.

Health Canada says it’s a “serious but rare type of lymphoma,” with the agency pegging the risk of BIA-ALCL at one in 3,565 (0.03%) for the Biocell implants. In Canada, more than 30 women have been diagnosed with BIA-ALCL.

Dona Murphy reads a letter from the hospital where she underwent a mastectomy after being diagnosed with breast cancer; it informed her that the implant used in the surgery has since been banned by Health Canada. (CBC)

Regulators in both Canada and the U.S. don’t recommend that women with the implants have them removed because the cancer is so rare. But they say women should check with their doctor if they have any symptoms, which include pain and swelling.

Paying for peace of mind?

While Murphy has no symptoms from her textured implant, she wants the device removed from her body. But the Ontario government has said that if the implant doesn’t affect her health, it’s up to her to pay to have it taken out.

“I can’t imagine why any woman would want to have it in them if there’s a potential — no matter how small — of causing cancer,” she said.

Patricia Mailman has two textured implants, put in after undergoing a double mastectomy in Halifax as part of her cancer treatment. When she found out about the ban, she too immediately wanted her implants replaced with non-textured ones.

She doesn’t have $10,000 needed to pay a plastic surgeon to have the explant done, she said, so she’s on a waiting list to have the Nova Scotia government pay, because the implants are causing her pain.

“We didn’t ask for the cancer in the first place, so we didn’t really ask for this either,” Mailman said.

Patricia Mailman had textured implants put in years ago after a double mastectomy. (CBC)

Textured breast implants were used in thousands of procedures in Canada beginning in 2006, with the pebble-like surface intended to act as a kind of Velcro, preventing the implant from sliding on the chest well.

The medical community started linking some breast implants to cancer in 2011.

BIA-ALCL is not breast cancer, but rather lymphoma that grows in the scar tissue surrounding the breast. It grows slowly and can usually be successfully treated by surgically removing the implants.

Risks involved with removal

Dr. Michael Weinberg, a plastic surgeon in Toronto, estimates he’s implanted about 100 pairs of textured implants. Now because of the ban, he says some of his former patients are scared, worried and asking for his advice.

“They are very emotional and I completely understand how they feel really badly,” he said.

Weinberg cautions that removing implants is a significant operation, both in terms of medical risks, as well as cosmetically.

The risks of implant removal include:

  • Infection.
  • Bleeding.
  • Scarring.

“You can’t guarantee when the implant is under the muscle that you’ll be able to take the whole capsule out,” said Weinberg, or the surrounding scar tissue that can stick to the ribs.

Still, for some women, the thought of possibly developing cancer is a worse risk.

Murphy is scheduled to have her implant removed in March, paying for it out of her own pocket. But, she points out, that’s something a lot of women can’t afford to do.

Cancer survivors are faced with difficult decisions months after textured implants were banned because of a rare cancer risk. The women must decide if the risks and costs of having implants removed outweigh the risk of leaving them in. 2:19

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What is the Delta variant of coronavirus with K417N mutation?

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 India said on Wednesday it has found around 40 cases of the Delta coronavirus variant carrying a mutation that appears to make it more transmissible, and advised states to increase testing.

Below is what we know about the variant.

WHAT IS DELTA PLUS?

The variant, called “Delta Plus” in India, was first reported in a Public Health England bulletin on June 11.

It is a sub-lineage of the Delta variant first detected in India and has acquired the spike protein mutation called K417N which is also found in the Beta variant first identified in South Africa.

Some scientists worry that the mutation, coupled with other existing features of the Delta variant, could make it more transmissible.

“The mutation K417N has been of interest as it is present in the Beta variant (B.1.351 lineage), which was reported to have immune evasion property,” India’s health ministry said in a statement.

Shahid Jameel, a top Indian virologist, said the K417N was known to reduce the effectiveness of a cocktail of therapeutic monoclonal antibodies.

WHERE ALL IT HAS BEEN FOUND?

As of June 16 https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/994839/Variants_of_Concern_VOC_Technical_Briefing_16.pdf, at least 197 cases has been found from 11 countries – Britain (36), Canada (1), India (8), Japan (15), Nepal (3), Poland (9), Portugal (22), Russia (1), Switzerland (18), Turkey (1), the United States (83).

India said on Wednesday around 40 cases of the variant have been observed in the states of Maharashtra, Kerala and Madhya Pradesh, with “no significant increase in prevalence”. The earliest case in India is from a sample taken on April 5.

Britain said its first 5 cases were sequenced on April 26 and they were contacts of individuals who had travelled from, or transited through, Nepal and Turkey.

No deaths were reported among the UK and Indian cases.

WHAT ARE THE WORRIES?

Studies are ongoing in India and globally to test the effectiveness of vaccines against this mutation.

“WHO is tracking this variant as part of the Delta variant, as we are doing for other Variants of Concern with additional mutations,” the World Health Organization (WHO) said in a statement sent to Reuters.

“For the moment, this variant does not seem to be common, currently accounting for only a small fraction of the Delta sequences … Delta and other circulating Variants of Concern remain a higher public health risk as they have demonstrated increases in transmission,” it said.

But India’s health ministry warned that regions where it has been found “may need to enhance their public health response by focusing on surveillance, enhanced testing, quick contact-tracing and priority vaccination.”

There are worries Delta Plus would inflict another wave of infections on India after it emerged from the world’s worst surge in cases only recently.

“The mutation itself may not lead to a third wave in India – that also depends on COVID-appropriate behaviour, but it could be one of the reasons,” said Tarun Bhatnagar, a scientist with the state-run Indian Council for Medical Research.

(Reporting by Shilpa Jamkhandikar in Pune, Bhargav Acharya and Ankur Banerjee in Bengaluru and Alistair Smout in London; Editing by Miyoung Kim and Giles Elgood)

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Colon Cancer Rates Have Increased: How Can You Improve Your Gut Health?

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The majority of colon cancer cases are more common among older citizens. However, research has found that colorectal cancer rates have been rising in healthy people under 50. The rate has increased over the ten years. Medical professionals recommend screening from age 45. A colorectal screening test is done to ensure that the individual does not have any signs of cancer.

A study found that there has been a surge in colorectal cancer in younger generations and could become the dominant cause of cancer-related deaths by 2030. Since the risk is alarming, everyone needs to take their gut health seriously. Here are some things that people can do to improve their well-being.

Consider Hydrotherapy

Hydrotherapy is a type of colon cleanse that treats digestive issues such as constipation and bloating. Chronic constipation can lead to colon cancer, so it is vital to deal with the issue before it worsens. Colon hydrotherapy is offered at a few places, including a wellness colonic clinic in Toronto where the staff is committed to providing solutions for their clients’ digestive health.

Cleansing your colon can help improve digestion, relieve constipation, reduce gas, rejuvenate skin, and increase energy. The process involves flushing the colon with a large volume of water. It can be beneficial to speak to the professionals at the clinic and discuss your concerns with them. They will educate you about the process and answer any concerns you may have. The treatment can seem overwhelming but can also be helpful for your gut health.

 

Consume Sensibly

Your food intake plays a significant role in your gut health. If you have gut problems, it may be worthwhile to speak to a doctor and change your diet. You should also consider finding out if you have any food intolerance. There may be trigger foods such as oil or dairy that could be causing discomfort.

Even if you do not have any problems with your food consumption, it is never wrong to watch what you eat. Foods with probiotics or high fibre content can be good for you. Eating the right foods can improve your overall health too.

Stay Hydrated

Water almost seems like a magical drink sometimes. From skin problems to digestive issues, it can improve many situations. Consuming a good amount of water every day can balance good bacteria in the gut and promote your health. Hydration can also help your organs function properly and improve cognitive function.

Say Goodbye to Extreme Stress

It can be challenging to bid farewell to stress forever. However, chronic high levels of stress can impact your abdomen and your overall health. There is a connection between the brain and gut, and stress can cause your stomach to become anxious.

Long-term stress can trigger several gut problems such as indigestion, constipation, or diarrhea. Look for ways to reduce stress levels so that your gut can remain healthy.

Some health problems are inevitable with age, but you can do your best to stay healthy and deal with any issues you face. Prepare yourself to fight any disease beforehand, and your body will thank you.

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Biden’s vaccine pledge ups pressure on rich countries to give more

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The United States on Thursday raised the pressure on other Group of Seven leaders to share their vaccine hoards to bring an end to the pandemic by pledging to donate 500 million doses of the Pfizer coronavirus vaccine to the world’s poorest countries.

The largest ever vaccine donation by a single country will cost the United States $3.5 billion but Washington expects no quid pro quo or favours for the gift, a senior Biden administration official told reporters.

U.S. President Joe Biden‘s move, on the eve of a summit of the world’s richest democracies, is likely to prompt other leaders to stump up more vaccines, though even vast numbers of vaccines would still not be enough to inoculate all of the world’s poor.

G7 leaders want to vaccinate the world by the end of 2022 to try to halt the COVID-19 pandemic that has killed more than 3.9 million people and devastated the global economy.

A senior Biden administration official described the gesture as a “major step forward that will supercharge the global effort” with the aim of “bringing hope to every corner of the world.” “We really want to underscore that this is fundamentally about a singular objective of saving lives,” the official said, adding that Washington was not seeking favours in exchange for the doses.

Vaccination efforts so far are heavily correlated with wealth: the United States, Europe, Israel and Bahrain are far ahead of other countries. A total of 2.2 billion people have been vaccinated so far out of a world population of nearly 8 billion, based on Johns Hopkins University data.

U.S. drugmaker Pfizer and its German partner BioNTech have agreed to supply the U.S. with the vaccines, delivering 200 million doses in 2021 and 300 million doses in the first half of 2022.

The shots, which will be produced at Pfizer’s U.S. sites, will be supplied at a not-for-profit price.

“Our partnership with the U.S. government will help bring hundreds of millions of doses of our vaccine to the poorest countries around the world as quickly as possible,” said Pfizer Chief Executive Albert Bourla.

‘DROP IN THE BUCKET’

Anti-poverty campaign group Oxfam called for more to be done to increase global production of vaccines.

“Surely, these 500 million vaccine doses are welcome as they will help more than 250 million people, but that’s still a drop in the bucket compared to the need across the world,” said Niko Lusiani, Oxfam America’s vaccine lead.

“We need a transformation toward more distributed vaccine manufacturing so that qualified producers worldwide can produce billions more low-cost doses on their own terms, without intellectual property constraints,” he said in a statement.

Another issue, especially in some poor countries, is the infrastructure for transporting the vaccines which often have to be stored at very cold temperatures.

Biden has also backed calls for a waiver of some vaccine intellectual property rights but there is no international consensus yet on how to proceed.

The new vaccine donations come on top of 80 million doses Washington has already pledged to donate by the end of June. There is also $2 billion in funding earmarked for the COVAX programme led by the World Health Organization (WHO) and the Global Alliance for Vaccines and Immunization (GAVI), the White House said.

GAVI and the WHO welcomed the initiative.

Washington is also taking steps to support local production of COVID-19 vaccines in other countries, including through its Quad initiative with Japan, India and Australia.

(Reporting by Steve Holland in St. Ives, England, Andrea Shalal in Washington and Caroline Copley in Berlin; Writing by Guy Faulconbridge and Keith Weir;Editing by Leslie Adler, David Evans, Emelia Sithole-Matarise, Giles Elgood and Jane Merriman)

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