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Colossal bet aims to revive, unleash woolly mammoth in Canada’s Arctic – Global News

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A private company wants to resurrect a gigantic species that once roamed the Earth — and it’ll spare no expense to make its plan a reality.

Sound familiar?

A new startup says it’s prepared to spend US$15 million on the Jurassic Parkesque dream of reviving the long-dead woolly mammoth, in hopes of one day restoring it to the tundra regions that it once called home.

Those tundra regions now belong to countries like Russia and Canada, which might have something to say about releasing big hairy elephant hybrids into their respective wildernesses. Those areas are also rapidly warming due to climate change, meaning they will look different from what they were when the last mammoth died 4,000 years ago.

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Nevertheless, a company called Colossal says it’s got enough private funding to potentially make its woolly dream come true through cutting-edge gene-editing techniques.

“Our teams have collected viable DNA samples, and are editing the genes that will allow this wonderful megafauna to once again thunder through the Arctic,” Colossal says on its website.

Biotech entrepreneur Ben Lamm and George Church, a renowned Harvard geneticist, announced their startup on Monday.

“Our goal is to make a cold-resistant elephant, but it is going to look and behave like a mammoth,” Church told the Evening Standard. “Not because we are trying to trick anybody, but because we want something that is functionally equivalent to the mammoth, that will enjoy its time at -40 Celsius, and do all the things that elephants and mammoths do.”

They also want to establish a population that will interbreed and carry on without human guidance.


Colossal co-founders Ben Lamm, left, and George Church are shown in this handout photo.


Business Wire

The co-founders aim to produce mammoth-elephant calves within the next six years, with the goal of establishing wild populations in northern Eurasia and North America in the future.

They’re framing it as a de-extinction effort that could also help the environment, especially if the mammoth hybrids can transform the tundra into fertile carbon-capturing grassland. Their method could also potentially be used to revive other extinct species in the future, including ones that died out because of humans.

Colossal’s plan is to use CRISPR, a genetic copy-and-paste tool, to combine mammoth DNA with that of its living cousin, the Asian elephant. The mammoth DNA will come from specimens recovered from the melting permafrost in Siberia, and the elephant DNA will be extracted from elephant skin cells.


Click to play video: 'Are gene-edited babies the future? How CRISPR technology works'



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Are gene-edited babies the future? How CRISPR technology works


Are gene-edited babies the future? How CRISPR technology works – Nov 28, 2018

Church says he’ll create a hybrid set of DNA that includes the cold-weather traits of the mammoth. This DNA will then replace the DNA inside an Asian elephant egg, and the egg will be implanted into a female elephant to carry it to term.

If all goes well, the elephant mother would give birth to a very hairy hybrid resembling the mammoths of old.

If it doesn’t go well… well… at least they’re not planning an amusement park around it?

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“I’m not making a bold prediction this is going to be easy,” Church told the New York Times. “But everything up to this point has been relatively easy. Every tissue we’ve gone after, we’ve been able to get a recipe for.”

The actual pregnancy might prove to be difficult, as Colossal expects the elephant mother to carry a hefty mammoth fetus for 18 to 22 months.

Adult woolly mammoths stood about two feet taller and weighed about two tons more than today’s Asian elephants, so the hybrid fetus might prove a challenge for its mother.

The whole project also presents a raft of ethical issues, according to several outside scientists who have commented on the proposal.

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Victoria Herridge of Natural History Museum said the whole thing seems “implausible” and riddled with questions about what happens once the creature is brought to life.

“What is this creature? Is it a new species? How many do you need?” she asked in an interview with the Evening Standard. “If they succeed, what will the needs be of an intelligent social creature? And what are our obligations to it?”

Heather Bushman, a philosopher at the London School of Economics, said she’s worried about the lives that the potential hybrid calves might lead.

“You don’t have a mother for a species that — if they are anything like elephants — has extraordinarily strong mother-infant bonds that last for a very long time,” she told the New York Times. “Once there is a little mammoth or two on the ground, who is making sure that they’re being looked after?”

Church has been on the side of bleeding-edge genetic experiments before. In 2018, for instance, he supported a Chinese scientist who claimed to have made a designer baby with immunity to HIV.

“I think this is justifiable,” Church told The Associated Press at the time.

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Colossal has secured roughly $15 million in private funding from various investors, including the Winklevoss twins.

But that money didn’t come easy. Church spent years trying to drum up investments, and the project didn’t take off until he piqued Lamm’s interest during a meeting in 2019.

“We had about $100,000 over the last 15 years, which is way, way less than any other project in my lab, but not through lack of enthusiasm,” Church told CNBC. “Ben came out of the blue, I think inspired at a distance from what he was reading about this very charismatic project, which was very underfunded.”

Lamm suggests the mammoth would be a proof of concept for Colossal’s technology, and that the same techniques could later be used for “thoughtful, disruptive conservation.”

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Colossal is not the first group to take aim at resurrecting the mammoth through gene editing. The California-based Revive & Restore Project also wants to see the woolly mammoth brought back to life.

Scientists have toyed with the idea of resurrecting mammoths for years, in large part because there are so many well-preserved bodies left over in the Russian permafrost. Those bodies are rich with various tissues and DNA, unlike the remains of dinosaurs, which typically turn to stone through the fossilization process.

In other words, Jurassic Park is still a Hollywood pipe dream, but a Pleistocene World might be in reach — especially if Colossal can deliver on its mammoth promise.

© 2021 Global News, a division of Corus Entertainment Inc.

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Here’s how Helene and other storms dumped a whopping 40 trillion gallons of rain on the South

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More than 40 trillion gallons of rain drenched the Southeast United States in the last week from Hurricane Helene and a run-of-the-mill rainstorm that sloshed in ahead of it — an unheard of amount of water that has stunned experts.

That’s enough to fill the Dallas Cowboys’ stadium 51,000 times, or Lake Tahoe just once. If it was concentrated just on the state of North Carolina that much water would be 3.5 feet deep (more than 1 meter). It’s enough to fill more than 60 million Olympic-size swimming pools.

“That’s an astronomical amount of precipitation,” said Ed Clark, head of the National Oceanic and Atmospheric Administration’s National Water Center in Tuscaloosa, Alabama. “I have not seen something in my 25 years of working at the weather service that is this geographically large of an extent and the sheer volume of water that fell from the sky.”

The flood damage from the rain is apocalyptic, meteorologists said. More than 100 people are dead, according to officials.

Private meteorologist Ryan Maue, a former NOAA chief scientist, calculated the amount of rain, using precipitation measurements made in 2.5-mile-by-2.5 mile grids as measured by satellites and ground observations. He came up with 40 trillion gallons through Sunday for the eastern United States, with 20 trillion gallons of that hitting just Georgia, Tennessee, the Carolinas and Florida from Hurricane Helene.

Clark did the calculations independently and said the 40 trillion gallon figure (151 trillion liters) is about right and, if anything, conservative. Maue said maybe 1 to 2 trillion more gallons of rain had fallen, much if it in Virginia, since his calculations.

Clark, who spends much of his work on issues of shrinking western water supplies, said to put the amount of rain in perspective, it’s more than twice the combined amount of water stored by two key Colorado River basin reservoirs: Lake Powell and Lake Mead.

Several meteorologists said this was a combination of two, maybe three storm systems. Before Helene struck, rain had fallen heavily for days because a low pressure system had “cut off” from the jet stream — which moves weather systems along west to east — and stalled over the Southeast. That funneled plenty of warm water from the Gulf of Mexico. And a storm that fell just short of named status parked along North Carolina’s Atlantic coast, dumping as much as 20 inches of rain, said North Carolina state climatologist Kathie Dello.

Then add Helene, one of the largest storms in the last couple decades and one that held plenty of rain because it was young and moved fast before it hit the Appalachians, said University of Albany hurricane expert Kristen Corbosiero.

“It was not just a perfect storm, but it was a combination of multiple storms that that led to the enormous amount of rain,” Maue said. “That collected at high elevation, we’re talking 3,000 to 6000 feet. And when you drop trillions of gallons on a mountain, that has to go down.”

The fact that these storms hit the mountains made everything worse, and not just because of runoff. The interaction between the mountains and the storm systems wrings more moisture out of the air, Clark, Maue and Corbosiero said.

North Carolina weather officials said their top measurement total was 31.33 inches in the tiny town of Busick. Mount Mitchell also got more than 2 feet of rainfall.

Before 2017’s Hurricane Harvey, “I said to our colleagues, you know, I never thought in my career that we would measure rainfall in feet,” Clark said. “And after Harvey, Florence, the more isolated events in eastern Kentucky, portions of South Dakota. We’re seeing events year in and year out where we are measuring rainfall in feet.”

Storms are getting wetter as the climate change s, said Corbosiero and Dello. A basic law of physics says the air holds nearly 4% more moisture for every degree Fahrenheit warmer (7% for every degree Celsius) and the world has warmed more than 2 degrees (1.2 degrees Celsius) since pre-industrial times.

Corbosiero said meteorologists are vigorously debating how much of Helene is due to worsening climate change and how much is random.

For Dello, the “fingerprints of climate change” were clear.

“We’ve seen tropical storm impacts in western North Carolina. But these storms are wetter and these storms are warmer. And there would have been a time when a tropical storm would have been heading toward North Carolina and would have caused some rain and some damage, but not apocalyptic destruction. ”

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Follow AP’s climate coverage at https://apnews.com/hub/climate

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Follow Seth Borenstein on Twitter at @borenbears

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Associated Press climate and environmental coverage receives support from several private foundations. See more about AP’s climate initiative here. The AP is solely responsible for all content.

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‘Big Sam’: Paleontologists unearth giant skull of Pachyrhinosaurus in Alberta

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It’s a dinosaur that roamed Alberta’s badlands more than 70 million years ago, sporting a big, bumpy, bony head the size of a baby elephant.

On Wednesday, paleontologists near Grande Prairie pulled its 272-kilogram skull from the ground.

They call it “Big Sam.”

The adult Pachyrhinosaurus is the second plant-eating dinosaur to be unearthed from a dense bonebed belonging to a herd that died together on the edge of a valley that now sits 450 kilometres northwest of Edmonton.

It didn’t die alone.

“We have hundreds of juvenile bones in the bonebed, so we know that there are many babies and some adults among all of the big adults,” Emily Bamforth, a paleontologist with the nearby Philip J. Currie Dinosaur Museum, said in an interview on the way to the dig site.

She described the horned Pachyrhinosaurus as “the smaller, older cousin of the triceratops.”

“This species of dinosaur is endemic to the Grand Prairie area, so it’s found here and nowhere else in the world. They are … kind of about the size of an Indian elephant and a rhino,” she added.

The head alone, she said, is about the size of a baby elephant.

The discovery was a long time coming.

The bonebed was first discovered by a high school teacher out for a walk about 50 years ago. It took the teacher a decade to get anyone from southern Alberta to come to take a look.

“At the time, sort of in the ’70s and ’80s, paleontology in northern Alberta was virtually unknown,” said Bamforth.

When paleontogists eventually got to the site, Bamforth said, they learned “it’s actually one of the densest dinosaur bonebeds in North America.”

“It contains about 100 to 300 bones per square metre,” she said.

Paleontologists have been at the site sporadically ever since, combing through bones belonging to turtles, dinosaurs and lizards. Sixteen years ago, they discovered a large skull of an approximately 30-year-old Pachyrhinosaurus, which is now at the museum.

About a year ago, they found the second adult: Big Sam.

Bamforth said both dinosaurs are believed to have been the elders in the herd.

“Their distinguishing feature is that, instead of having a horn on their nose like a triceratops, they had this big, bony bump called a boss. And they have big, bony bumps over their eyes as well,” she said.

“It makes them look a little strange. It’s the one dinosaur that if you find it, it’s the only possible thing it can be.”

The genders of the two adults are unknown.

Bamforth said the extraction was difficult because Big Sam was intertwined in a cluster of about 300 other bones.

The skull was found upside down, “as if the animal was lying on its back,” but was well preserved, she said.

She said the excavation process involved putting plaster on the skull and wooden planks around if for stability. From there, it was lifted out — very carefully — with a crane, and was to be shipped on a trolley to the museum for study.

“I have extracted skulls in the past. This is probably the biggest one I’ve ever done though,” said Bamforth.

“It’s pretty exciting.”

This report by The Canadian Press was first published Sept. 25, 2024.

The Canadian Press. All rights reserved.

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The ancient jar smashed by a 4-year-old is back on display at an Israeli museum after repair

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TEL AVIV, Israel (AP) — A rare Bronze-Era jar accidentally smashed by a 4-year-old visiting a museum was back on display Wednesday after restoration experts were able to carefully piece the artifact back together.

Last month, a family from northern Israel was visiting the museum when their youngest son tipped over the jar, which smashed into pieces.

Alex Geller, the boy’s father, said his son — the youngest of three — is exceptionally curious, and that the moment he heard the crash, “please let that not be my child” was the first thought that raced through his head.

The jar has been on display at the Hecht Museum in Haifa for 35 years. It was one of the only containers of its size and from that period still complete when it was discovered.

The Bronze Age jar is one of many artifacts exhibited out in the open, part of the Hecht Museum’s vision of letting visitors explore history without glass barriers, said Inbal Rivlin, the director of the museum, which is associated with Haifa University in northern Israel.

It was likely used to hold wine or oil, and dates back to between 2200 and 1500 B.C.

Rivlin and the museum decided to turn the moment, which captured international attention, into a teaching moment, inviting the Geller family back for a special visit and hands-on activity to illustrate the restoration process.

Rivlin added that the incident provided a welcome distraction from the ongoing war in Gaza. “Well, he’s just a kid. So I think that somehow it touches the heart of the people in Israel and around the world,“ said Rivlin.

Roee Shafir, a restoration expert at the museum, said the repairs would be fairly simple, as the pieces were from a single, complete jar. Archaeologists often face the more daunting task of sifting through piles of shards from multiple objects and trying to piece them together.

Experts used 3D technology, hi-resolution videos, and special glue to painstakingly reconstruct the large jar.

Less than two weeks after it broke, the jar went back on display at the museum. The gluing process left small hairline cracks, and a few pieces are missing, but the jar’s impressive size remains.

The only noticeable difference in the exhibit was a new sign reading “please don’t touch.”

The Canadian Press. All rights reserved.

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