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Description:
LJ100 ®Patented extract of Eurycoma Longifolia
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1.Tsutsui K., Ubuka T, et al. Gonadotropin-inhibitory hormone (GnIH): Discovery, progress and prospect, General and Comparative Endocrinology. Volume 177, Issue 3, 1 July 2012, Pages 305-314
2.Travison, T.G., Araujo, A.B., et al., A population-level decline in serum testosterone levels in American men. J Clin Endocrinol Metab. 2007 Jan;92(1):196-202. doi: 10.1210/jc.2006-1375. Epub 2006 Oct 24.
3.Leisegang K., Finelli R., et al. Eurycoma longifolia (Jack) Improves Serum Total Testosterone in Men: A Systematic Review and Meta-Analysis of Clinical Trials. Medicina (Kaunas). 2022 Aug; 58(8): 1047. Published online 2022 Aug 4. doi: 10.3390/medicina58081047
4.Simone Y. Loo, Laurent Azoulay, et al. Cardiovascular and Cerebrovascular Safety of Testosterone Replacement Therapy Among Aging Men with Low Testosterone Levels: A Cohort Study. The American Journal of Medicine, 2019; DOI: 10.1016/j.amjmed.2019.03.022
5.Mike Kocsis (Medically Review By Dr. George Touliatos), July 13, 2023, TRT is a lifetime commitment.
6.Amir Shahreza Patel, Joon Yau Leong, et al. Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility. World J Mens Health. 2019 Jan; 37(1): 45–54. Published online 2018 Oct 10. doi: 10.5534/wjmh.180036
7.Abbas Kanani MRPharmS, 09 September 2022, What to do if Viagra is giving you a headache
8.Sara Lindberg (Medically Reviewed By Matt Coward, MD, FACS), What Does It Mean When Viagra Is Not Working Anymore? October 29, 2020
9.George N. Nassar; Stephen W. Leslie. Physiology, Testosterone. Treasure Island (FL): StatPearls Publishing; 2023 Jan.
10.Cleveland Clinic, 02 September 2022, Low Testosterone – Symptoms And Causes
11.Cleveland Clinic, 16 March 2022, Hypothalamus
12.Bill Ganzel, The Ganzel Group Et Al., 2007, Shrinking Farm Numbers
13.Donald R Davis, Melvin D Epp, Hugh D Riordan, Changes in USDA food composition data for 43 garden crops, 1950 to 1999. J Am Coll Nutr. 2004 Dec;23(6):669-82. doi: 10.1080/07315724.2004.10719409
14.Scientific American, 27 April 2011, Dirt Poor: Have Fruits and Vegetables Become Less Nutritious?
15.Anne-Marie Berenice Mayer, Historical changes in the mineral content of fruits and vegetables. July 1997. British Food Journal 99(6):207-211 DOI:10.1108/00070709710181540
16.Thomas G Travison 1, Andre B Araujo, Amy B O’Donnell, Varant Kupelian, John B McKinlay, A population-level decline in serum testosterone levels in American men. J Clin Endocrinol Metab. 2007 Jan;92(1):196-202. doi: 10.1210/jc.2006-1375. Epub 2006 Oct 24.
17.Peter Celec, Daniela Ostatníková, Július Hodosy. On the effects of testosterone on brain behavioral functions. Front Neurosci. 2015; 9: 12. Published online 2015 Feb 17. doi: 10.3389/fnins.2015.00012
18.Shaheed Ur Rehman, Kevin Choe, and Hye Hyun Yoo*. Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules. 2016 Mar; 21(3): 331. Published online 2016 Mar 10. doi: 10.3390/molecules 21030331
19.M I B M Tambi 1, M K Imran, R R Henkel. Standardized water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia. 2012 May;44 Suppl 1:226-30. doi: 10.1111/j.1439-0272.2011.01168.x. Epub 2011 Jun 15.
20.Mohd Ismail Bin Mohd Tambi and M. Kamarul Imran. Eurycoma longifolia Jack in managing idiopathic male infertility. Asian J Androl. 2010 May; 12(3): 376–380. Published online 2010 Mar 29. doi: 10.1038/aja.2010.7
21.Anna Smith Haghighi (Medically Reviewed By Matt Coward, MD, FACS), What to know about estrogen in men. March 6, 2023
22.Dalin Chen, Hongliang Li, Wen Li, Shuo Feng, and Dingsen Deng. Kaempferia parviflora and Its Methoxyflavones: Chemistry and Biological Activities. Evid Based Complement Alternat Med. 2018; 2018: 4057456. Published online 2018 Dec 16. doi: 10.1155/2018/4057456
23.Kamla Kant Shukla 1, Abbas Ali Mahdi, Mohammad Kaleem Ahmad, Satya Narain Shankhwar, Singh Rajender, Shyam Pyari Jaiswar. Mucuna pruriens improves male fertility by its action on the hypothalamus-pituitary-gonadal axis. Fertil Steril. 2009 Dec;92(6):1934-40. doi: 10.1016/j.fertnstert.2008.09.045. Epub 2008 Oct 29.
24.Shukla KK, Mahdi AA, Ahmad MK, Shankhwar SN, Rajender S, Jaiswar SP Mucuna pruriens improves male fertility by its action on the hypothalamus-pituitary-gonadal axis. Fertil Steril.(2009 Dec)
25.Lucia Raffaella Lampariello,1 Alessio Cortelazzo,2 Roberto Guerranti,2 Claudia Sticozzi,3 and Giuseppe Valacchi3,4,* The Magic Velvet Bean of Mucuna pruriens. J Tradit Complement Med. 2012 Oct-Dec; 2(4): 331–339. doi: 10.1016/s2225-4110(16)30119-5
26.Prakash Seppan, et al. Therapeutic potential of Mucuna pruriens (Linn.) on ageing induced damage in dorsal nerve of the penis and its implication on erectile function: an experimental study using albino rats. The Aging Male Volume 23, 2020 – Issue 5: 15 Feb 2018
27.Waluga Plaingam, Siriporn Sangsuthum, Wannee Angkhasirisap, and Tewin Tencomnaob. Kaempferia parviflora rhizome extract and Myristica fragrans volatile oil increase the levels of monoamine neurotransmitters and impact the proteomic profiles in the rat hippocampus: Mechanistic insights into their neuroprotective effects. J Tradit Complement Med. 2017 Oct; 7(4): 538–552. Published online 2017 Jun 15. doi: 10.1016/j.jtcme.2017.01.002
28.K. Chandrasekhar, Jyoti Kapoor, and Sridhar Anishetty. A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. Indian J Psychol Med. 2012 Jul-Sep; 34(3): 255–262. doi: 10.4103/0253-7176.106022
29.Kaye K. Brownlee, Alex W. Moore, and Anthony C. Hackney. Relationship Between Circulating Cortisol and Testosterone: Influence of Physical Exercise. J Sports Sci Med. 2005 Mar; 4(1): 76–83. Published online 2005 Mar 1.
30.Dnyanraj Choudhary, MD, Sauvik Bhattacharyya, MPharm, PhD, and Kedar Joshi, MD. Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract. J Evid Based Complementary Altern Med. 2017 Jan; 22(1): 96–106. Published online 2016 Apr 6. doi: 10.1177/2156587216641830
31.Lopresti AL, Drummond PD, Smith SJ. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males . American Journal of Men’s Health. 2019;13(2):155798831983598.
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Please note that the information we provide is not intended to replace consultation with a qualified medical professional. We encourage you to inform your physician of changes you make to your lifestyle and discuss these with him or her. For questions or concerns about any medical conditions you may have, please contact your doctor.Statements on this website have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using our products.The website’s content and the product for sale is based upon the author’s opinion and is provided solely on an “AS IS” and “AS AVAILABLE” basis. You should do your own research and confirm the information with other sources when searching for information regarding health issues and always review the information carefully with your professional health care provider before using any of the protocols presented on this website and/or the product sold here.ClickBank is the retailer of products on this site. CLICKBANK® is a registered trademark of Click Sales, Inc., a Delaware corporation located at 1444 South Entertainment Ave, Suite 410, Boise, Idaho, 83709, USA and used by permission. ClickBank’s role as retailer does not constitute an endorsement, approval or review of these products or any claim, statement or opinion used in promotion of these products. * For international shipping (outside of the United States), shipping fees will apply.
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comp-cb is backed with a 60 Day No Questions Asked Money Back Guarantee. If within the first 60 days of receipt you are not satisfied with Wake Up Lean™, you can request a refund by sending an email to the address given inside the product and we will immediately refund your entire purchase price, with no questions asked.
Skinstitut Holiday Gift Kits take the stress out of gifting
Toronto, October 31, 2024 – Beauty gifts are at the top of holiday wish lists this year, and Laser Clinics Canada, a leader in advanced beauty treatments and skincare, is taking the pressure out of seasonal shopping. Today, Laser Clincs Canada announces the arrival of its 2024 Holiday Gift Kits, courtesy of Skinstitut, the exclusive skincare line of Laser Clinics Group.
In time for the busy shopping season, the limited-edition Holiday Gifts Kits are available in Laser Clinics locations in the GTA and Ottawa. Clinics are conveniently located in popular shopping centers, including Hillcrest Mall, Square One, CF Sherway Gardens, Scarborough Town Centre, Rideau Centre, Union Station and CF Markville. These limited-edition Kits are available on a first come, first served basis.
“These kits combine our best-selling products, bundled to address the most relevant skin concerns we’re seeing among our clients,” says Christina Ho, Senior Brand & LAM Manager at Laser Clinics Canada. “With several price points available, the kits offer excellent value and suit a variety of gift-giving needs, from those new to cosmeceuticals to those looking to level up their skincare routine. What’s more, these kits are priced with a savings of up to 33 per cent so gift givers can save during the holiday season.
There are two kits to select from, each designed to address key skin concerns and each with a unique theme — Brightening Basics and Hydration Heroes.
Brightening Basics is a mix of everyday essentials for glowing skin for all skin types. The bundle comes in a sleek pink, reusable case and includes three full-sized products: 200ml gentle cleanser, 50ml Moisture Defence (normal skin) and 30ml1% Hyaluronic Complex Serum. The Brightening Basics kit is available at $129, a saving of 33 per cent.
Hydration Heroes is a mix of hydration essentials and active heroes that cater to a wide variety of clients. A perfect stocking stuffer, this bundle includes four deluxe products: Moisture 15 15 ml Defence for normal skin, 10 ml 1% Hyaluronic Complex Serum, 10 ml Retinol Serum and 50 ml Expert Squalane Cleansing Oil. The kit retails at $59.
In addition to the 2024 Holiday Gifts Kits, gift givers can easily add a Laser Clinic Canada gift card to the mix. Offering flexibility, recipients can choose from a wide range of treatments offered by Laser Clinics Canada, or they can expand their collection of exclusive Skinstitut products.
Brightening Basics 2024 Holiday Gift Kit by Skinstitut, available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.
Hydration Heroes 2024 Holiday Gift Kit by Skinstitut – available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.
LONDON (AP) — Most people have accumulated a pile of data — selfies, emails, videos and more — on their social media and digital accounts over their lifetimes. What happens to it when we die?
It’s wise to draft a will spelling out who inherits your physical assets after you’re gone, but don’t forget to take care of your digital estate too. Friends and family might treasure files and posts you’ve left behind, but they could get lost in digital purgatory after you pass away unless you take some simple steps.
Here’s how you can prepare your digital life for your survivors:
Apple
The iPhone maker lets you nominate a “ legacy contact ” who can access your Apple account’s data after you die. The company says it’s a secure way to give trusted people access to photos, files and messages. To set it up you’ll need an Apple device with a fairly recent operating system — iPhones and iPads need iOS or iPadOS 15.2 and MacBooks needs macOS Monterey 12.1.
For iPhones, go to settings, tap Sign-in & Security and then Legacy Contact. You can name one or more people, and they don’t need an Apple ID or device.
You’ll have to share an access key with your contact. It can be a digital version sent electronically, or you can print a copy or save it as a screenshot or PDF.
Take note that there are some types of files you won’t be able to pass on — including digital rights-protected music, movies and passwords stored in Apple’s password manager. Legacy contacts can only access a deceased user’s account for three years before Apple deletes the account.
Google
Google takes a different approach with its Inactive Account Manager, which allows you to share your data with someone if it notices that you’ve stopped using your account.
When setting it up, you need to decide how long Google should wait — from three to 18 months — before considering your account inactive. Once that time is up, Google can notify up to 10 people.
You can write a message informing them you’ve stopped using the account, and, optionally, include a link to download your data. You can choose what types of data they can access — including emails, photos, calendar entries and YouTube videos.
There’s also an option to automatically delete your account after three months of inactivity, so your contacts will have to download any data before that deadline.
Facebook and Instagram
Some social media platforms can preserve accounts for people who have died so that friends and family can honor their memories.
When users of Facebook or Instagram die, parent company Meta says it can memorialize the account if it gets a “valid request” from a friend or family member. Requests can be submitted through an online form.
The social media company strongly recommends Facebook users add a legacy contact to look after their memorial accounts. Legacy contacts can do things like respond to new friend requests and update pinned posts, but they can’t read private messages or remove or alter previous posts. You can only choose one person, who also has to have a Facebook account.
You can also ask Facebook or Instagram to delete a deceased user’s account if you’re a close family member or an executor. You’ll need to send in documents like a death certificate.
TikTok
The video-sharing platform says that if a user has died, people can submit a request to memorialize the account through the settings menu. Go to the Report a Problem section, then Account and profile, then Manage account, where you can report a deceased user.
Once an account has been memorialized, it will be labeled “Remembering.” No one will be able to log into the account, which prevents anyone from editing the profile or using the account to post new content or send messages.
X
It’s not possible to nominate a legacy contact on Elon Musk’s social media site. But family members or an authorized person can submit a request to deactivate a deceased user’s account.
Passwords
Besides the major online services, you’ll probably have dozens if not hundreds of other digital accounts that your survivors might need to access. You could just write all your login credentials down in a notebook and put it somewhere safe. But making a physical copy presents its own vulnerabilities. What if you lose track of it? What if someone finds it?
Instead, consider a password manager that has an emergency access feature. Password managers are digital vaults that you can use to store all your credentials. Some, like Keeper,Bitwarden and NordPass, allow users to nominate one or more trusted contacts who can access their keys in case of an emergency such as a death.
But there are a few catches: Those contacts also need to use the same password manager and you might have to pay for the service.
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Is there a tech challenge you need help figuring out? Write to us at onetechtip@ap.org with your questions.
The Canadian Paediatric Society says doctors should regularly screen children for reading difficulties and dyslexia, calling low literacy a “serious public health concern” that can increase the risk of other problems including anxiety, low self-esteem and behavioural issues, with lifelong consequences.
New guidance issued Wednesday says family doctors, nurses, pediatricians and other medical professionals who care for school-aged kids are in a unique position to help struggling readers access educational and specialty supports, noting that identifying problems early couldhelp kids sooner — when it’s more effective — as well as reveal other possible learning or developmental issues.
The 10 recommendations include regular screening for kids aged four to seven, especially if they belong to groups at higher risk of low literacy, including newcomers to Canada, racialized Canadians and Indigenous Peoples. The society says this can be done in a two-to-three-minute office-based assessment.
Other tips encourage doctors to look for conditions often seen among poor readers such as attention-deficit hyperactivity disorder; to advocate for early literacy training for pediatric and family medicine residents; to liaise with schools on behalf of families seeking help; and to push provincial and territorial education ministries to integrate evidence-based phonics instruction into curriculums, starting in kindergarten.
Dr. Scott McLeod, one of the authors and chair of the society’s mental health and developmental disabilities committee, said a key goal is to catch kids who may be falling through the cracks and to better connect families to resources, including quicker targeted help from schools.
“Collaboration in this area is so key because we need to move away from the silos of: everything educational must exist within the educational portfolio,” McLeod said in an interview from Calgary, where he is a developmental pediatrician at Alberta Children’s Hospital.
“Reading, yes, it’s education, but it’s also health because we know that literacy impacts health. So I think that a statement like this opens the window to say: Yes, parents can come to their health-care provider to get advice, get recommendations, hopefully start a collaboration with school teachers.”
McLeod noted that pediatricians already look for signs of low literacy in young children by way of a commonly used tool known as the Rourke Baby Record, which offers a checklist of key topics, such as nutrition and developmental benchmarks, to cover in a well-child appointment.
But he said questions about reading could be “a standing item” in checkups and he hoped the society’s statement to medical professionals who care for children “enhances their confidence in being a strong advocate for the child” while spurring partnerships with others involved in a child’s life such as teachers and psychologists.
The guidance said pediatricians also play a key role in detecting and monitoring conditions that often coexist with difficulty reading such as attention-deficit hyperactivity disorder, but McLeod noted that getting such specific diagnoses typically involves a referral to a specialist, during which time a child continues to struggle.
He also acknowledged that some schools can be slow to act without a specific diagnosis from a specialist, and even then a child may end up on a wait list for school interventions.
“Evidence-based reading instruction shouldn’t have to wait for some of that access to specialized assessments to occur,” he said.
“My hope is that (by) having an existing statement or document written by the Canadian Paediatric Society … we’re able to skip a few steps or have some of the early interventions present,” he said.
McLeod added that obtaining specific assessments from medical specialists is “definitely beneficial and advantageous” to know where a child is at, “but having that sort of clear, thorough assessment shouldn’t be a barrier to intervention starting.”
McLeod said the society was partly spurred to act by 2022’s “Right to Read Inquiry Report” from the Ontario Human Rights Commission, which made 157 recommendations to address inequities related to reading instruction in that province.
He called the new guidelines “a big reminder” to pediatric providers, family doctors, school teachers and psychologists of the importance of literacy.
“Early identification of reading difficulty can truly change the trajectory of a child’s life.”
This report by The Canadian Press was first published Oct. 23, 2024.
