adplus-dvertising
Connect with us

Business

Trump says vaccine ready within weeks; Pfizer says some patients show side effects

Published

 on

President Donald Trump reiterated his belief that a coronavirus vaccine may arrive before Election Day, even as top administration health officials have rebuffed such a timeline — and vaccine makers have vowed to wait for safety and efficacy data.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”In an interview with Fox &amp; Friends, Trump said a vaccine could be ready to distribute in as little as four to eight weeks, a highly condensed timeline for approval and distribution that many experts have questioned.” data-reactid=”18″>In an interview with Fox & Friends, Trump said a vaccine could be ready to distribute in as little as four to eight weeks, a highly condensed timeline for approval and distribution that many experts have questioned.

“We’re going to have a vaccine in a matter of weeks, it could be four weeks it could be eight weeks…will it be before the Election, it could be…we’ll start delivering it immediately upon getting it,” he said.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”The aggressive timetable has heightened the debate surrounding the deployment of a potential COVID-19 cure, which is perceived as crucial to restarting public life and ending the threat of lockdowns.” data-reactid=”20″>The aggressive timetable has heightened the debate surrounding the deployment of a potential COVID-19 cure, which is perceived as crucial to restarting public life and ending the threat of lockdowns.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”While not referencing a specific date or timeline, Trump’s own health officials, including U.S. Food and Drug Commissioner Stephen Hahn, have reiterated a commitment to safety in approving any drug. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases has said a vaccine by Election Day was unlikely, but at least theoretically possible.” data-reactid=”21″>While not referencing a specific date or timeline, Trump’s own health officials, including U.S. Food and Drug Commissioner Stephen Hahn, have reiterated a commitment to safety in approving any drug. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases has said a vaccine by Election Day was unlikely, but at least theoretically possible.

Since the FDA exists under the executive branch, and therefore under the White House— as does the U.S. Department of Health and Human Services (HHS)— it is possible for the White House to exert pressure, and there are provisions that give HHS Sec. Alex Azar the authority to push for an emergency authorization.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”But in an article Tuesday in the New England Journal of Medicine, Operation Warp Speed officials, including director Moncef Slaoui, indicated a focus on January 2021 for vaccine distribution and approval.” data-reactid=”23″>But in an article Tuesday in the New England Journal of Medicine, Operation Warp Speed officials, including director Moncef Slaoui, indicated a focus on January 2021 for vaccine distribution and approval.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”Still, complications in human trials may emerge as a hurdle to rapidly deploying any inoculation— an expectation in the clinical trial process. On Tuesday, Pfizer (PFE) said some of its trial subjects displayed mild-to-moderate after-effects to either the company’s experimental coronavirus vaccine, or a placebo. The data showed that fatigue was the most common feeling, executives said on an investor call.” data-reactid=”24″>Still, complications in human trials may emerge as a hurdle to rapidly deploying any inoculation— an expectation in the clinical trial process. On Tuesday, Pfizer (PFE) said some of its trial subjects displayed mild-to-moderate after-effects to either the company’s experimental coronavirus vaccine, or a placebo. The data showed that fatigue was the most common feeling, executives said on an investor call.

Many southern states are seeing a week-over-week drop in cases. (Graphic: David Foster/Yahoo Finance)
Many southern states are seeing a week-over-week drop in cases. (Graphic: David Foster/Yahoo Finance)

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”The recent hiccup with AstraZeneca’s (AZN) clinical trials of Oxford University’s vaccine is another indicator of a possible delay — while U.K. Phase 3 trials have resumed, the U.S. remains on hold. The National Institutes of Health is concerned about the mysterious illness that put the U.K. trial on hold and says the company hasn’t been forthcoming with helpful information. The company has said it believes it can still have a vaccine approved by the end of the year.” data-reactid=”37″>The recent hiccup with AstraZeneca’s (AZN) clinical trials of Oxford University’s vaccine is another indicator of a possible delay — while U.K. Phase 3 trials have resumed, the U.S. remains on hold. The National Institutes of Health is concerned about the mysterious illness that put the U.K. trial on hold and says the company hasn’t been forthcoming with helpful information. The company has said it believes it can still have a vaccine approved by the end of the year.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”Moderna (MRNA), a key frontrunner heavily funded by federal reesearch dollars, has also committed to the end of the year. Meanwhile, collaborators Pfizer and BioNTech (BNTX) have said they are on track to at least have results by the end of October — but not in time for an October 22 FDA meeting that will hash out details of approval and distribution of vaccines.” data-reactid=”38″>Moderna (MRNA), a key frontrunner heavily funded by federal reesearch dollars, has also committed to the end of the year. Meanwhile, collaborators Pfizer and BioNTech (BNTX) have said they are on track to at least have results by the end of October — but not in time for an October 22 FDA meeting that will hash out details of approval and distribution of vaccines.

But Pfizer also said that the FDA has indicated it will weigh an emergency use authorization based on a subset of the trial population. Though trials are upwards of 30,000 for Phase 3, and Pfizer has said it will expand to 44,000, the FDA is only requiring safety data for 6,000— 3,000 vaccinated and 3,000 placebo, executives said on the call.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”Trump also referenced Johnson &amp; Johnson (JNJ), which is using a similar technology to AstraZeneca, and has not even entered late-stage trials yet for its candidate, though the company has said they will this month. In the wake of the AstraZeneca scare, some participants in a Phase 2 study in Spain have backed out.” data-reactid=”40″>Trump also referenced Johnson & Johnson (JNJ), which is using a similar technology to AstraZeneca, and has not even entered late-stage trials yet for its candidate, though the company has said they will this month. In the wake of the AstraZeneca scare, some participants in a Phase 2 study in Spain have backed out.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”Meanwhile, other players are ramping up their output potential. Novavax (NVAX), which is in Phase 2 trials, announced Tuesday the company signed a deal with the Serum Institute of India for 1 billion doses. That pushes Novavax’s output to 2 billion doses by mid-2021.” data-reactid=”45″>Meanwhile, other players are ramping up their output potential. Novavax (NVAX), which is in Phase 2 trials, announced Tuesday the company signed a deal with the Serum Institute of India for 1 billion doses. That pushes Novavax’s output to 2 billion doses by mid-2021.

<p class=”canvas-atom canvas-text Mb(1.0em) Mb(0)–sm Mt(0.8em)–sm” type=”text” content=”The Serum Institute is the largest vaccine producer globally, and has been tapped by other companies, including AstraZeneca, to help with the global production of a Covid-19 vaccine. CEO Adar Poonawalla, recently told Financial Times that many vaccine companies have not ramped up quickly enough to meet the global demand, and it is likely the world won’t be fully supplied until 2024.” data-reactid=”46″>The Serum Institute is the largest vaccine producer globally, and has been tapped by other companies, including AstraZeneca, to help with the global production of a Covid-19 vaccine. CEO Adar Poonawalla, recently told Financial Times that many vaccine companies have not ramped up quickly enough to meet the global demand, and it is likely the world won’t be fully supplied until 2024.

 

S

Source link

Business

Telus prioritizing ‘most important customers,’ avoiding ‘unprofitable’ offers: CFO

Published

 on

 

Telus Corp. says it is avoiding offering “unprofitable” discounts as fierce competition in the Canadian telecommunications sector shows no sign of slowing down.

The company said Friday it had fewer net new customers during its third quarter compared with the same time last year, as it copes with increasingly “aggressive marketing and promotional pricing” that is prompting more customers to switch providers.

Telus said it added 347,000 net new customers, down around 14.5 per cent compared with last year. The figure includes 130,000 mobile phone subscribers and 34,000 internet customers, down 30,000 and 3,000, respectively, year-over-year.

The company reported its mobile phone churn rate — a metric measuring subscribers who cancelled their services — was 1.09 per cent in the third quarter, up from 1.03 per cent in the third quarter of 2023. That included a postpaid mobile phone churn rate of 0.90 per cent in its latest quarter.

Telus said its focus is on customer retention through its “industry-leading service and network quality, along with successful promotions and bundled offerings.”

“The customers we have are the most important customers we can get,” said chief financial officer Doug French in an interview.

“We’ve, again, just continued to focus on what matters most to our customers, from a product and customer service perspective, while not loading unprofitable customers.”

Meanwhile, Telus reported its net income attributable to common shares more than doubled during its third quarter.

The telecommunications company said it earned $280 million, up 105.9 per cent from the same three-month period in 2023. Earnings per diluted share for the quarter ended Sept. 30 was 19 cents compared with nine cents a year earlier.

It reported adjusted net income was $413 million, up 10.7 per cent year-over-year from $373 million in the same quarter last year. Operating revenue and other income for the quarter was $5.1 billion, up 1.8 per cent from the previous year.

Mobile phone average revenue per user was $58.85 in the third quarter, a decrease of $2.09 or 3.4 per cent from a year ago. Telus said the drop was attributable to customers signing up for base rate plans with lower prices, along with a decline in overage and roaming revenues.

It said customers are increasingly adopting unlimited data and Canada-U.S. plans which provide higher and more stable ARPU on a monthly basis.

“In a tough operating environment and relative to peers, we view Q3 results that were in line to slightly better than forecast as the best of the bunch,” said RBC analyst Drew McReynolds in a note.

Scotiabank analyst Maher Yaghi added that “the telecom industry in Canada remains very challenging for all players, however, Telus has been able to face these pressures” and still deliver growth.

The Big 3 telecom providers — which also include Rogers Communications Inc. and BCE Inc. — have frequently stressed that the market has grown more competitive in recent years, especially after the closing of Quebecor Inc.’s purchase of Freedom Mobile in April 2023.

Hailed as a fourth national carrier, Quebecor has invested in enhancements to Freedom’s network while offering more affordable plans as part of a set of commitments it was mandated by Ottawa to agree to.

The cost of telephone services in September was down eight per cent compared with a year earlier, according to Statistics Canada’s most recent inflation report last month.

“I think competition has been and continues to be, I’d say, quite intense in Canada, and we’ve obviously had to just manage our business the way we see fit,” said French.

Asked how long that environment could last, he said that’s out of Telus’ hands.

“What I can control, though, is how we go to market and how we lead with our products,” he said.

“I think the conditions within the market will have to adjust accordingly over time. We’ve continued to focus on digitization, continued to bring our cost structure down to compete, irrespective of the price and the current market conditions.”

Still, Canada’s telecom regulator continues to warn providers about customers facing more charges on their cellphone and internet bills.

On Tuesday, CRTC vice-president of consumer, analytics and strategy Scott Hutton called on providers to ensure they clearly inform their customers of charges such as early cancellation fees.

That followed statements from the regulator in recent weeks cautioning against rising international roaming fees and “surprise” price increases being found on their bills.

Hutton said the CRTC plans to launch public consultations in the coming weeks that will focus “on ensuring that information is clear and consistent, making it easier to compare offers and switch services or providers.”

“The CRTC is concerned with recent trends, which suggest that Canadians may not be benefiting from the full protections of our codes,” he said.

“We will continue to monitor developments and will take further action if our codes are not being followed.”

French said any initiative to boost transparency is a step in the right direction.

“I can’t say we are perfect across the board, but what I can say is we are absolutely taking it under consideration and trying to be the best at communicating with our customers,” he said.

“I think everyone looking in the mirror would say there’s room for improvement.”

This report by The Canadian Press was first published Nov. 8, 2024.

Companies in this story: (TSX:T)

Source link

Continue Reading

Business

TC Energy cuts cost estimate for Southeast Gateway pipeline project in Mexico

Published

 on

 

CALGARY – TC Energy Corp. has lowered the estimated cost of its Southeast Gateway pipeline project in Mexico.

It says it now expects the project to cost between US$3.9 billion and US$4.1 billion compared with its original estimate of US$4.5 billion.

The change came as the company reported a third-quarter profit attributable to common shareholders of C$1.46 billion or $1.40 per share compared with a loss of C$197 million or 19 cents per share in the same quarter last year.

Revenue for the quarter ended Sept. 30 totalled C$4.08 billion, up from C$3.94 billion in the third quarter of 2023.

TC Energy says its comparable earnings for its latest quarter amounted to C$1.03 per share compared with C$1.00 per share a year earlier.

The average analyst estimate had been for a profit of 95 cents per share, according to LSEG Data & Analytics.

This report by The Canadian Press was first published Nov. 7, 2024.

Companies in this story: (TSX:TRP)

The Canadian Press. All rights reserved.

Source link

Continue Reading

Business

BCE reports Q3 loss on asset impairment charge, cuts revenue guidance

Published

 on

 

BCE Inc. reported a loss in its latest quarter as it recorded $2.11 billion in asset impairment charges, mainly related to Bell Media’s TV and radio properties.

The company says its net loss attributable to common shareholders amounted to $1.24 billion or $1.36 per share for the quarter ended Sept. 30 compared with a profit of $640 million or 70 cents per share a year earlier.

On an adjusted basis, BCE says it earned 75 cents per share in its latest quarter compared with an adjusted profit of 81 cents per share in the same quarter last year.

“Bell’s results for the third quarter demonstrate that we are disciplined in our pursuit of profitable growth in an intensely competitive environment,” BCE chief executive Mirko Bibic said in a statement.

“Our focus this quarter, and throughout 2024, has been to attract higher-margin subscribers and reduce costs to help offset short-term revenue impacts from sustained competitive pricing pressures, slow economic growth and a media advertising market that is in transition.”

Operating revenue for the quarter totalled $5.97 billion, down from $6.08 billion in its third quarter of 2023.

BCE also said it now expects its revenue for 2024 to fall about 1.5 per cent compared with earlier guidance for an increase of zero to four per cent.

The company says the change comes as it faces lower-than-anticipated wireless product revenue and sustained pressure on wireless prices.

BCE added 33,111 net postpaid mobile phone subscribers, down 76.8 per cent from the same period last year, which was the company’s second-best performance on the metric since 2010.

It says the drop was driven by higher customer churn — a measure of subscribers who cancelled their service — amid greater competitive activity and promotional offer intensity. BCE’s monthly churn rate for the category was 1.28 per cent, up from 1.1 per cent during its previous third quarter.

The company also saw 11.6 per cent fewer gross subscriber activations “due to more targeted promotional offers and mobile device discounting compared to last year.”

Bell’s wireless mobile phone average revenue per user was $58.26, down 3.4 per cent from $60.28 in the third quarter of the prior year.

This report by The Canadian Press was first published Nov. 7, 2024.

Companies in this story: (TSX:BCE)

The Canadian Press. All rights reserved.

Source link

Continue Reading

Trending