The biggest test yet of an experimental COVID-19 vaccine got underway Monday with the first of some 30,000 Americans rolling up their sleeves to receive shots created by the U.S. government as part of the all-out global race to stop the outbreak.
Final-stage testing of the vaccine, developed by the National Institutes of Health and Moderna Inc., began with volunteers at various U.S. sites given either a real shot or a dummy without being told which.
It will be months before results trickle in, and there is no guarantee the vaccine will ultimately work against the scourge that has killed about 650,000 people around the world, including almost 150,000 in the U.S.
As if to underline how high the stakes are, there were more setbacks in efforts to contain the virus.
In Washington, the White House disclosed that national security adviser Robert O’Brien has the coronavirus — the highest-ranking U.S. official to test positive so far.
The move to restart the national pastime ran into trouble just five days into the long-delayed season: Two major league baseball games scheduled for Monday night were called off as the Miami Marlins coped with an outbreak — the Marlins’ home opener against the Baltimore Orioles, and the New York Yankees’ game in Philadelphia, where the Marlins used the clubhouse over the weekend.
On virus relief, Republicans on Capitol Hill planned to roll out a $1 trillion package that could include a new round of $,1200 stimulus checks but reduce the extra $600 a week in federal unemployment benefits that are expiring for millions of Americans this week.
In Europe, rising infections in Spain and other countries caused alarm only weeks after nations reopened their borders in hopes of reviving tourism. Over the weekend, Britain imposed a 14-day quarantine on travellers arriving from Spain, Norway ordered a 10-day quarantine for people returning from the entire Iberian peninsula, and France urged its citizens not to visit Spain’s Catalonia region.
In Binghamton, New York, nurse Melissa Harting received one of the first injections of the Moderna vaccine candidate. saying she was volunteering “to do my part to help out.”
“I’m excited,” Harting said. Especially with family members in front-line jobs that could expose them to the virus, she said, “doing our part to eradicate it is very important to me.”
After two doses, scientists will closely track which participants — those getting real shots, or a dummy — experience more infections as they go about their daily routines, especially in hard-hit areas where the virus still is spreading. Testing is planned at close to 90 sites, officials said.
“Unfortunately for the United States of America, we have plenty of infections right now” to get that answer, the government’s top infectious-disease expert, Dr. Anthony Fauci, said recently.
Several other vaccines made by China and by Britain’s Oxford University began smaller final-stage tests in Brazil and other hard-hit countries earlier this month. But the U.S. requires its own tests of any vaccine that might be used in the country.
Every month through the fall, the government-funded COVID-19 Prevention Network will roll out a new study of a leading candidate, each with 30,000 volunteers, to test not only whether the shots work but whether they are safe.
The final U.S. study of the Oxford shot is set to begin in August, followed by a candidate from Johnson & Johnson in September and one from Novavax in October. Pfizer Inc. plans its own 30,000-person study this summer.
It normally takes years to create a vaccine from scratch, but scientists are setting speed records this time, spurred by knowledge that vaccination is the world’s best hope against the pandemic.
Governments around the world are already trying to stockpile millions of doses of the leading candidates so that immunizations can begin immediately if the vaccines win approval. But the first available doses will most likely be reserved for people at highest risk.
“We’re optimistic, cautiously optimistic” that the vaccine will work and that “toward the end of the year” there will be data to prove it, Dr. Stephen Hoge, president of Massachusetts-based Moderna, told a House subcommittee last week.
TORONTO – Canada Goose Holdings Inc. says it has signed a deal that will result in the creation of its first eyewear collection.
The deal announced on Thursday by the Toronto-based luxury apparel company comes in the form of an exclusive, long-term global licensing agreement with Marchon Eyewear Inc.
The terms and value of the agreement were not disclosed, but Marchon produces eyewear for brands including Lacoste, Nike, Calvin Klein, Ferragamo, Longchamp and Zeiss.
Marchon plans to roll out both sunglasses and optical wear under the Canada Goose name next spring, starting in North America.
Canada Goose says the eyewear will be sold through optical retailers, department stores, Canada Goose shops and its website.
Canada Goose CEO Dani Reiss told The Canadian Press in August that he envisioned his company eventually expanding into eyewear and luggage.
This report by The Canadian Press was first published Sept. 19, 2024.
Almost seven years since news broke of an alleged conspiracy to fix the price of packaged bread across Canada, the saga isn’t over: the Competition Bureau continues to investigate the companies that may have been involved, and two class-action lawsuits continue to work their way through the courts.
Here’s a timeline of key events in the bread price-fixing case.
Oct. 31, 2017: The Competition Bureau says it’s investigating allegations of bread price-fixing and that it was granted search warrants in the case. Several grocers confirm they are co-operating in the probe.
Dec. 19, 2017: Loblaw and George Weston say they participated in an “industry-wide price-fixing arrangement” to raise the price of packaged bread. The companies say they have been co-operating in the Competition Bureau’s investigation since March 2015, when they self-reported to the bureau upon discovering anti-competitive behaviour, and are receiving immunity from prosecution. They announce they are offering $25 gift cards to customers amid the ongoing investigation into alleged bread price-fixing.
Jan. 31, 2018: In court documents, the Competition Bureau says at least $1.50 was added to the price of a loaf of bread between about 2001 and 2016.
Dec. 20, 2019: A class-action lawsuit in a Quebec court against multiple grocers and food companies is certified against a number of companies allegedly involved in bread price-fixing, including Loblaw, George Weston, Metro, Sobeys, Walmart Canada, Canada Bread and Giant Tiger (which have all denied involvement, except for Loblaw and George Weston, which later settled with the plaintiffs).
Dec. 31, 2021: A class-action lawsuit in an Ontario court covering all Canadian residents except those in Quebec who bought packaged bread from a company named in the suit is certified against roughly the same group of companies.
June 21, 2023: Bakery giant Canada Bread Co. is fined $50 million after pleading guilty to four counts of price-fixing under the Competition Act as part of the Competition Bureau’s ongoing investigation.
Oct. 25 2023: Canada Bread files a statement of defence in the Ontario class action denying participating in the alleged conspiracy and saying any anti-competitive behaviour it participated in was at the direction and to the benefit of its then-majority owner Maple Leaf Foods, which is not a defendant in the case (neither is its current owner Grupo Bimbo). Maple Leaf calls Canada Bread’s accusations “baseless.”
Dec. 20, 2023: Metro files new documents in the Ontario class action accusing Loblaw and its parent company George Weston of conspiring to implicate it in the alleged scheme, denying involvement. Sobeys has made a similar claim. The two companies deny the allegations.
July 25, 2024: Loblaw and George Weston say they agreed to pay a combined $500 million to settle both the Ontario and Quebec class-action lawsuits. Loblaw’s share of the settlement includes a $96-million credit for the gift cards it gave out years earlier.
Sept. 12, 2024: Canada Bread files new documents in Ontario court as part of the class action, claiming Maple Leaf used it as a “shield” to avoid liability in the alleged scheme. Maple Leaf was a majority shareholder of Canada Bread until 2014, and the company claims it’s liable for any price-fixing activity. Maple Leaf refutes the claims.
This report by The Canadian Press was first published Sept. 19, 2024.
Companies in this story: (TSX:L, TSX:MFI, TSX:MRU, TSX:EMP.A, TSX:WN)
TORONTO – TD Bank Group, which is mired in a money laundering scandal in the U.S., says chief executive Bharat Masrani will retire next year.
Masrani, who will retire officially on April 10, 2025, says the bank’s, “anti-money laundering challenges,” took place on his watch and he takes full responsibility.
The bank named Raymond Chun, TD’s group head, Canadian personal banking, as his successor.
As part of a transition plan, Chun will become chief operating officer on Nov. 1 before taking over the top job when Masrani steps down at the bank’s annual meeting next year.
TD also announced that Riaz Ahmed, group head, wholesale banking and president and CEO of TD Securities, will retire at the end of January 2025.
TD has taken billions in charges related to ongoing U.S. investigations into the failure of its anti-money laundering program.
This report by The Canadian Press was first published Sept. 19, 2024.
