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Injectable HIV drug less accessible to patients in B.C. than other provinces: doctor

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British Columbians with HIV have less access to an injectable drug compared to patients elsewhere in the country who can get a shot every two months instead of taking a daily pill, says an infectious diseases specialist.

Dr. Brian Conway questioned why the BC Centre for Excellence in HIV/AIDS, and not the prescribing health practitioner, decides who qualifies for the extended-release injectable drug called Cabenuva.

The centre procures, distributes and monitors HIV medications in B.C., and also reviews applications from prescribers, unlike in other provinces without such a centralized system.

Conway said the centre declined approval of Cabenuva for all 15 patients he has applied for since the spring. Six of the applicants were rejected simply because they were deemed to be responding well to the drug in a pill form, he added.

“It’s a long process to apply, which in my case has led to zero approvals,” Conway said of the drug that he believes should be prescribed based on discussions between care providers and patients, without “unnecessary” oversight.

“Instead of it just being a regular prescription as it is for all the other HIV medications we have, it’s a 25-question questionnaire and supporting documentation.”

A spokesman for the centre said it has received 39 applications for Cabenuva since last year and 15 of them have been approved while 11 are still pending and 13 were withdrawn or have not been processed for other reasons.

Patients could be denied the injectable for various reasons, including not being able to tolerate one or both of the drugs it contains or having adverse reactions to them, the centre said.

Dr. Julio Montaner, the centre’s executive director, was not available to provide details about the decision-making process.

Conway said 10 of his approximately 500 patients with HIV are taking Cabenuva because they got it in a clinical trial and continued taking it before Canada became the first country to approve the long-lasting treatment three years ago.

There are many benefits to the injectable versus a daily pill and patients should have the option without a third party making that decision, he said.

“Some people just don’t want to be reminded every day that they have HIV. They’re afraid people will find their pills,” he said.

Cabenuva is a combination of the drugs cabotegravir and rilpivirine for patients aged 12 and older. Studies have shown it is as effective as oral therapy in treating the virus that can be transmitted through sexual contact, by sharing drug-injection equipment and to children during pregnancy, delivery and breastfeeding.

The injectable HIV drug is considered a breakthrough in the evolution of medicines for patients with the virus who once had to take multiple daily pills, often with debilitating, visible side effects such as loss of fat and muscle and sunken cheeks.

The BC Centre for Excellence in HIV/AIDS spokesman said the organization has had an administrative role in dealing with HIV medications since the 1990s, based on a decision by the province, which provides funding.

He said in an email that “this is different from other jurisdictions across the country and elsewhere.”

Conway said the centre has cited lack of staff to provide the injection at a doctor’s office or clinic, which must also be equipped with a fridge to store the medication. However, many offices, including his own, have a fridge and administering the shot would not be different from many other types of injections, he added.

The B.C. Health Ministry did not respond to questions about why patients do not have direct access to Cabenuva with a prescription from their doctor. It said the centre establishes guidelines for health-care providers to be involved in prescribing and monitoring of all antiretroviral drugs.

Sarah Chown, executive director of AIDS Vancouver, said members whose applications for Cabenuva have been rejected do not understand why that decision was made by an organization whose decision makers had not met them.

She said applicants who would rather get a shot every couple of months are required to provide a letter describing why they are unable to take a pill every day.

“We don’t believe that patients should have to prove they are unable to continue oral medications in order to access the freedom and the privacy and the flexibility that comes with long-acting treatment,” she said.

“We’re curious and frustrated that here in B.C. people are still getting rejected, especially because we know that some of those folks would be approved in other provinces.”

The Ontario Ministry of Health said any HIV patient whose doctor has prescribed Cabenuva can get it at a pharmacy, the same as any other medication.

“There is no requirement to apply for case-by-case approval,” it said. “As such, there is also no application process or denial.”

Dr. Jonathan Angel, director of the HIV clinic at The Ottawa Hospital, said the prescribing of Cabenuva is an inexplicably “complex” issue for patients in B.C.

“They’re the ones that haven’t had a loud enough or strong enough voice to get these drugs in B.C.,” he said.

Angel, who has prescribed Cabenuva to 127 patients since 2020, said some patients would rather continue taking a daily pill because they don’t like injections but the choice should be theirs.

The cost of Cabenuva is believed to be similar to the most common daily HIV medication, called Biktarvy, so that should not be a factor in not approving it for patients in B.C., he said.

Individual provinces negotiate prices on some medications directly with drug companies, and those costs are confidential.

This report by The Canadian Press was first published Nov. 12, 2023.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

 

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What’s the greatest holiday gift: lips, hair, skin? Give the gift of great skin this holiday season

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Give the gift of great skin this holiday season

Skinstitut Holiday Gift Kits take the stress out of gifting

Toronto, October 31, 2024 – Beauty gifts are at the top of holiday wish lists this year, and Laser Clinics Canada, a leader in advanced beauty treatments and skincare, is taking the pressure out of seasonal shopping. Today, Laser Clincs Canada announces the arrival of its 2024 Holiday Gift Kits, courtesy of Skinstitut, the exclusive skincare line of Laser Clinics Group.

In time for the busy shopping season, the limited-edition Holiday Gifts Kits are available in Laser Clinics locations in the GTA and Ottawa. Clinics are conveniently located in popular shopping centers, including Hillcrest Mall, Square One, CF Sherway Gardens, Scarborough Town Centre, Rideau Centre, Union Station and CF Markville. These limited-edition Kits are available on a first come, first served basis.

“These kits combine our best-selling products, bundled to address the most relevant skin concerns we’re seeing among our clients,” says Christina Ho, Senior Brand & LAM Manager at Laser Clinics Canada. “With several price points available, the kits offer excellent value and suit a variety of gift-giving needs, from those new to cosmeceuticals to those looking to level up their skincare routine. What’s more, these kits are priced with a savings of up to 33 per cent so gift givers can save during the holiday season.

There are two kits to select from, each designed to address key skin concerns and each with a unique theme — Brightening Basics and Hydration Heroes.

Brightening Basics is a mix of everyday essentials for glowing skin for all skin types. The bundle comes in a sleek pink, reusable case and includes three full-sized products: 200ml gentle cleanser, 50ml Moisture Defence (normal skin) and 30ml1% Hyaluronic Complex Serum. The Brightening Basics kit is available at $129, a saving of 33 per cent.

Hydration Heroes is a mix of hydration essentials and active heroes that cater to a wide variety of clients. A perfect stocking stuffer, this bundle includes four deluxe products: Moisture 15 15 ml Defence for normal skin, 10 ml 1% Hyaluronic Complex Serum, 10 ml Retinol Serum and 50 ml Expert Squalane Cleansing Oil. The kit retails at $59.

In addition to the 2024 Holiday Gifts Kits, gift givers can easily add a Laser Clinic Canada gift card to the mix. Offering flexibility, recipients can choose from a wide range of treatments offered by Laser Clinics Canada, or they can expand their collection of exclusive Skinstitut products.

 

Brightening Basics 2024 Holiday Gift Kit by Skinstitut, available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

Hydration Heroes 2024 Holiday Gift Kit by Skinstitut – available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

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Here is how to prepare your online accounts for when you die

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LONDON (AP) — Most people have accumulated a pile of data — selfies, emails, videos and more — on their social media and digital accounts over their lifetimes. What happens to it when we die?

It’s wise to draft a will spelling out who inherits your physical assets after you’re gone, but don’t forget to take care of your digital estate too. Friends and family might treasure files and posts you’ve left behind, but they could get lost in digital purgatory after you pass away unless you take some simple steps.

Here’s how you can prepare your digital life for your survivors:

Apple

The iPhone maker lets you nominate a “ legacy contact ” who can access your Apple account’s data after you die. The company says it’s a secure way to give trusted people access to photos, files and messages. To set it up you’ll need an Apple device with a fairly recent operating system — iPhones and iPads need iOS or iPadOS 15.2 and MacBooks needs macOS Monterey 12.1.

For iPhones, go to settings, tap Sign-in & Security and then Legacy Contact. You can name one or more people, and they don’t need an Apple ID or device.

You’ll have to share an access key with your contact. It can be a digital version sent electronically, or you can print a copy or save it as a screenshot or PDF.

Take note that there are some types of files you won’t be able to pass on — including digital rights-protected music, movies and passwords stored in Apple’s password manager. Legacy contacts can only access a deceased user’s account for three years before Apple deletes the account.

Google

Google takes a different approach with its Inactive Account Manager, which allows you to share your data with someone if it notices that you’ve stopped using your account.

When setting it up, you need to decide how long Google should wait — from three to 18 months — before considering your account inactive. Once that time is up, Google can notify up to 10 people.

You can write a message informing them you’ve stopped using the account, and, optionally, include a link to download your data. You can choose what types of data they can access — including emails, photos, calendar entries and YouTube videos.

There’s also an option to automatically delete your account after three months of inactivity, so your contacts will have to download any data before that deadline.

Facebook and Instagram

Some social media platforms can preserve accounts for people who have died so that friends and family can honor their memories.

When users of Facebook or Instagram die, parent company Meta says it can memorialize the account if it gets a “valid request” from a friend or family member. Requests can be submitted through an online form.

The social media company strongly recommends Facebook users add a legacy contact to look after their memorial accounts. Legacy contacts can do things like respond to new friend requests and update pinned posts, but they can’t read private messages or remove or alter previous posts. You can only choose one person, who also has to have a Facebook account.

You can also ask Facebook or Instagram to delete a deceased user’s account if you’re a close family member or an executor. You’ll need to send in documents like a death certificate.

TikTok

The video-sharing platform says that if a user has died, people can submit a request to memorialize the account through the settings menu. Go to the Report a Problem section, then Account and profile, then Manage account, where you can report a deceased user.

Once an account has been memorialized, it will be labeled “Remembering.” No one will be able to log into the account, which prevents anyone from editing the profile or using the account to post new content or send messages.

X

It’s not possible to nominate a legacy contact on Elon Musk’s social media site. But family members or an authorized person can submit a request to deactivate a deceased user’s account.

Passwords

Besides the major online services, you’ll probably have dozens if not hundreds of other digital accounts that your survivors might need to access. You could just write all your login credentials down in a notebook and put it somewhere safe. But making a physical copy presents its own vulnerabilities. What if you lose track of it? What if someone finds it?

Instead, consider a password manager that has an emergency access feature. Password managers are digital vaults that you can use to store all your credentials. Some, like Keeper,Bitwarden and NordPass, allow users to nominate one or more trusted contacts who can access their keys in case of an emergency such as a death.

But there are a few catches: Those contacts also need to use the same password manager and you might have to pay for the service.

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Is there a tech challenge you need help figuring out? Write to us at onetechtip@ap.org with your questions.

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Pediatric group says doctors should regularly screen kids for reading difficulties

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The Canadian Paediatric Society says doctors should regularly screen children for reading difficulties and dyslexia, calling low literacy a “serious public health concern” that can increase the risk of other problems including anxiety, low self-esteem and behavioural issues, with lifelong consequences.

New guidance issued Wednesday says family doctors, nurses, pediatricians and other medical professionals who care for school-aged kids are in a unique position to help struggling readers access educational and specialty supports, noting that identifying problems early couldhelp kids sooner — when it’s more effective — as well as reveal other possible learning or developmental issues.

The 10 recommendations include regular screening for kids aged four to seven, especially if they belong to groups at higher risk of low literacy, including newcomers to Canada, racialized Canadians and Indigenous Peoples. The society says this can be done in a two-to-three-minute office-based assessment.

Other tips encourage doctors to look for conditions often seen among poor readers such as attention-deficit hyperactivity disorder; to advocate for early literacy training for pediatric and family medicine residents; to liaise with schools on behalf of families seeking help; and to push provincial and territorial education ministries to integrate evidence-based phonics instruction into curriculums, starting in kindergarten.

Dr. Scott McLeod, one of the authors and chair of the society’s mental health and developmental disabilities committee, said a key goal is to catch kids who may be falling through the cracks and to better connect families to resources, including quicker targeted help from schools.

“Collaboration in this area is so key because we need to move away from the silos of: everything educational must exist within the educational portfolio,” McLeod said in an interview from Calgary, where he is a developmental pediatrician at Alberta Children’s Hospital.

“Reading, yes, it’s education, but it’s also health because we know that literacy impacts health. So I think that a statement like this opens the window to say: Yes, parents can come to their health-care provider to get advice, get recommendations, hopefully start a collaboration with school teachers.”

McLeod noted that pediatricians already look for signs of low literacy in young children by way of a commonly used tool known as the Rourke Baby Record, which offers a checklist of key topics, such as nutrition and developmental benchmarks, to cover in a well-child appointment.

But he said questions about reading could be “a standing item” in checkups and he hoped the society’s statement to medical professionals who care for children “enhances their confidence in being a strong advocate for the child” while spurring partnerships with others involved in a child’s life such as teachers and psychologists.

The guidance said pediatricians also play a key role in detecting and monitoring conditions that often coexist with difficulty reading such as attention-deficit hyperactivity disorder, but McLeod noted that getting such specific diagnoses typically involves a referral to a specialist, during which time a child continues to struggle.

He also acknowledged that some schools can be slow to act without a specific diagnosis from a specialist, and even then a child may end up on a wait list for school interventions.

“Evidence-based reading instruction shouldn’t have to wait for some of that access to specialized assessments to occur,” he said.

“My hope is that (by) having an existing statement or document written by the Canadian Paediatric Society … we’re able to skip a few steps or have some of the early interventions present,” he said.

McLeod added that obtaining specific assessments from medical specialists is “definitely beneficial and advantageous” to know where a child is at, “but having that sort of clear, thorough assessment shouldn’t be a barrier to intervention starting.”

McLeod said the society was partly spurred to act by 2022’s “Right to Read Inquiry Report” from the Ontario Human Rights Commission, which made 157 recommendations to address inequities related to reading instruction in that province.

He called the new guidelines “a big reminder” to pediatric providers, family doctors, school teachers and psychologists of the importance of literacy.

“Early identification of reading difficulty can truly change the trajectory of a child’s life.”

This report by The Canadian Press was first published Oct. 23, 2024.

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