Health
Model With Lifestyle, Health Behavior Information Predicts CKD
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TUESDAY, Jan. 31, 2023 (HealthDay News) — Self-reported lifestyle and health behavior information can predict incident chronic kidney disease (CKD), according to a study published in the January issue of the Clinical Journal of the American Society of Nephrology.
Ariana J. Noel, M.D., from the University of Ottawa in Canada, and colleagues developed and validated a survey-based prediction equation to identify individuals at risk for incident CKD. Data were obtained from 22,200 adults with an estimated glomerular filtration rate (eGFR) ≥70 mL/min/1.73 m2 who completed a comprehensive general population health survey between 2000 and 2015. Demographics, comorbidities, lifestyle factors, diet, and mood were included in prediction equations. Models with and without baseline eGFR were derived and validated externally in 15,522 participants from the U.K. Biobank. The primary outcome was new-onset CKD.
The researchers found that during a median follow-up of 4.2 years, new-onset CKD occurred in 1,981 participants (9 percent). Lifestyle factors (smoking, alcohol, physical activity) and comorbid illnesses (diabetes, hypertension, cancer) were included in the final models. For individuals with and without a baseline eGFR measure, the model was discriminating (five-year C statistic, 83.5 and 81.0, respectively) and was well calibrated. The five-year C-statistic was 78.1 and 66.0 in external validation with and without baseline eGFR, respectively, and maintained calibration.
“Our equation demonstrated excellent discrimination and calibration, and may serve as a patient-facing tool to improve CKD awareness and education,” the authors write.
Several authors disclosed financial ties to the biopharmaceutical industry.
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Alberta Health Services (AHS) has confirmed a case of measles in Edmonton, and is advising the public that the individual was out in public while infectious.
Measles is an extremely contagious disease that is spread easily through the air, and can only be prevented through immunization.
AHS says individuals who were in the following locations during the specified dates and times, may have been exposed to measles.
- April 16
- Edmonton International Airport, international arrivals and baggage claim area — between 3:20 p.m. and 6 p.m.
- April 20
- Stollery Children’s Hospital Emergency Department — between 5 a.m. to 3 p.m.
- April 22
- 66th Medical Clinic (13635 66 St NW Edmonton) — between 12:15 p.m. to 3:30 p.m.
- Pharmacy 66 (13637 66 St NW Edmonton) — between 12:15 p.m. to 3:30 p.m.
- April 23
- Stollery Children’s Hospital Emergency Department — between 4:40 a.m. to 9:33 a.m.
AHS says anyone who attended those locations during those times is at risk of developing measles if they’ve not had two documented doses of measles-containing vaccine.
Those who have not had two doses, who are pregnant, under one year of age, or have a weakened immune system are at greatest risk of getting measles and should contact Health Link at 1-877-720-0707.
Symptoms
Symptoms of measles include a fever of 38.3° C or higher, cough, runny nose, and/or red eyes, a red blotchy rash that appears three to seven days after fever starts, beginning behind the ears and on the face and spreading down the body and then to the arms and legs.
If you have any of these symptoms stay home and call Health Link.
In Alberta, measles vaccine is offered, free of charge, through Alberta’s publicly funded immunization program. Children in Alberta typically receive their first dose of measles vaccine at 12 months of age, and their second dose at 18 months of age.
Health
U.S. tightens rules for dairy cows a day after bird flu virus fragments found in pasteurized milk samples – Toronto Star
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Infected cows were already prohibited from being transported out of state, but that was based on the physical characteristics of the milk, which looks curdled when a cow is infected, or a cow has decreased lactation or low appetite, both symptoms of infection.
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