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Ontario man’s cross-Canada cycling trip helps researchers understand how exercise impacts Parkinson’s disease

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After he was diagnosed with Parkinson’s disease, Steve Iseman set out on an 8,000-kilometre trip across Canada to raise money and awareness about the disorder.

But what he experienced when it came to his symptoms during that trip piqued the interest of researchers at the University of Guelph.

Iseman, 57, who lives in Toronto, said the diagnosis a decade ago was “devastating news and frankly, it changed everything.”

Parkinson’s is a neurodegenerative disease that can impact a person’s ability to move and speak. For Iseman, it causes muscle stiffness and brain fog. There is no cure and Parkinson Canada says more than 100,000 Canadians live with the disease.

Iseman said he tried to hide the diagnosis from his friends for about five years before he decided to be open about having Parkinson’s and what it was doing to him.

He worked to stay active because he found physical activity helped alleviate his symptoms.

“I came to recognize the benefits of cycling as a way to treat the symptoms of Parkinson’s disease.”

That led to his decision to do an 85-day cross-country trip, called Spinning Wheels Tour, to raise awareness about the disease.

“Specifically, we were trying to engage with other people who had Parkinson’s, three out of four of which are in hiding or otherwise disconnected from the Parkinson’s community, and sort of draw them in,” he said.

“I was trying to get our voices together.”

Unique research opportunity

At the same time Iseman was starting his cross-country tour in 2022, Philip Millar, a University of Guelph human health and nutritional science associate professor and researcher, was doing an exercise clinical trial that was funded by Parkinson Canada.

“We thought it was a really unique opportunity to be able to test him before and after such a really large kind of dose of exercise.”

The study into Iseman’s trip across Canada and the benefits he saw have been published in the journal Physiological Reports.

Philip Millar is an associate professor who researches cardiovascular physiology at the University of Guelph. (University of Guelph)

Millar said he was aware Iseman was already taking part in regular exercise and was physically fit, doing an average of about 300 minutes per week of cycling, “more than double what the average recommended guideline is.”

“We were unsure of how much more benefits he might see.”

It was thought that, given his physical abilities, Millar wouldn’t see any additional benefit from the cycling trip across Canada.

“That’s not really what we saw at all,” Millar said.

“We saw across almost all of our parameters, he got fitter, some of his motor symptoms decreased, he got stronger.”

Millar said while the really high-volume, high-intensity workout Iseman was doing “isn’t practical for recommending to patients … it is encouraging that it will tell us that there really isn’t an upper bounds to the benefits.”

Exercise is good, more is even be better

Iseman said he definitely felt the benefits on the bike ride — so much so that one day, he tried to go without taking any of his medications.

“It wasn’t great — the symptoms were still there — but it was a testament to the fact that it crossed my mind,” he said.

Millar said they tested Iseman using different scales and ratings, and noted:

  • On the Unified Parkinson Disease Rating Scale Part III, his motor score decreased 44 per cent, from 46 to 26.
  • Iseman’s ability to generate power through knee extensions increased 12 per cent over the trip.
  • His score on a standard test to measure Parkinson’s fatigue, the PFS‐16, decreased 32 per cent, from a 3.4 to 2.3.

Millar said the big takeaway isn’t that people with Parkinson’s should work their way up to being able to cycle across Canada.

Man on bike wearing a mask cycles in a lab. A technician watches results come up on computer screens.
Steven Iseman performs a cycling test in the Human Health and Performance Lab at the University of Guelph. (University of Guelph)

Instead, he said, the message is that exercise is good and more is even be better.

“We would have expected that [Iseman] would have already gained a lot of those benefits because he was already doing 300 minutes a week of exercise. So, you know, some might argue that there isn’t going to be room for anymore modification,” Millar said.

“After the trip, when we compare his aerobic fitness to healthy age and sex-matched controls, he was about 150 per cent of normal. So you know, here’s someone that has had Parkinson’s for, at the time, about eight years, and his fitness level is running 150 per cent of what the average Canadian for his age and sex is.”

Iseman’s story ‘an inspiration’

While it’s a review of the experience of one person, Karen Lee, president and CEO of Parkinson Canada, said Iseman’s story is “an inspiration and demonstrates the resilience of the Parkinson’s community.”

The Parkinson Canada National Research Program has invested $31 million in projects since 1981, including Millar’s work, and Lee said in an emailed statement that Iseman’s experience has been proven through other research.

“We have seen time and time again that exercise has positive benefits for people with Parkinson’s,” Lee said.

“The most important takeaway from this research is that it helps equip people with Parkinson’s with information to make informed decisions about the best approaches to manage the disease.”

Man on bicycle beside sign that says "Quebec"
Iseman kept a blog of his travels across the country and posted photos from the Spinning Wheels Tour to Facebook. (Spinning Wheels Tour/Facebook)

The research on the exercise trials Millar was working on in 2022 when Iseman was doing his ride across Canada are set to be published later this year.

As for Iseman, he has plans to go to northern Norway for a cycling event that “I can’t resist.”

Then, the Spinning Wheels Tour is coming back this summer. They plan to start this time from the Arctic Ocean, where there are “surprisingly few roads,” Iseman said.

“It’s going to be done as a relay and I’m only going to be doing a bit of it,” he said. “If all goes according to plan, we’ll start at the Arctic Ocean and come south.”

 

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What’s the greatest holiday gift: lips, hair, skin? Give the gift of great skin this holiday season

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Give the gift of great skin this holiday season

Skinstitut Holiday Gift Kits take the stress out of gifting

Toronto, October 31, 2024 – Beauty gifts are at the top of holiday wish lists this year, and Laser Clinics Canada, a leader in advanced beauty treatments and skincare, is taking the pressure out of seasonal shopping. Today, Laser Clincs Canada announces the arrival of its 2024 Holiday Gift Kits, courtesy of Skinstitut, the exclusive skincare line of Laser Clinics Group.

In time for the busy shopping season, the limited-edition Holiday Gifts Kits are available in Laser Clinics locations in the GTA and Ottawa. Clinics are conveniently located in popular shopping centers, including Hillcrest Mall, Square One, CF Sherway Gardens, Scarborough Town Centre, Rideau Centre, Union Station and CF Markville. These limited-edition Kits are available on a first come, first served basis.

“These kits combine our best-selling products, bundled to address the most relevant skin concerns we’re seeing among our clients,” says Christina Ho, Senior Brand & LAM Manager at Laser Clinics Canada. “With several price points available, the kits offer excellent value and suit a variety of gift-giving needs, from those new to cosmeceuticals to those looking to level up their skincare routine. What’s more, these kits are priced with a savings of up to 33 per cent so gift givers can save during the holiday season.

There are two kits to select from, each designed to address key skin concerns and each with a unique theme — Brightening Basics and Hydration Heroes.

Brightening Basics is a mix of everyday essentials for glowing skin for all skin types. The bundle comes in a sleek pink, reusable case and includes three full-sized products: 200ml gentle cleanser, 50ml Moisture Defence (normal skin) and 30ml1% Hyaluronic Complex Serum. The Brightening Basics kit is available at $129, a saving of 33 per cent.

Hydration Heroes is a mix of hydration essentials and active heroes that cater to a wide variety of clients. A perfect stocking stuffer, this bundle includes four deluxe products: Moisture 15 15 ml Defence for normal skin, 10 ml 1% Hyaluronic Complex Serum, 10 ml Retinol Serum and 50 ml Expert Squalane Cleansing Oil. The kit retails at $59.

In addition to the 2024 Holiday Gifts Kits, gift givers can easily add a Laser Clinic Canada gift card to the mix. Offering flexibility, recipients can choose from a wide range of treatments offered by Laser Clinics Canada, or they can expand their collection of exclusive Skinstitut products.

 

Brightening Basics 2024 Holiday Gift Kit by Skinstitut, available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

Hydration Heroes 2024 Holiday Gift Kit by Skinstitut – available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

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Here is how to prepare your online accounts for when you die

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LONDON (AP) — Most people have accumulated a pile of data — selfies, emails, videos and more — on their social media and digital accounts over their lifetimes. What happens to it when we die?

It’s wise to draft a will spelling out who inherits your physical assets after you’re gone, but don’t forget to take care of your digital estate too. Friends and family might treasure files and posts you’ve left behind, but they could get lost in digital purgatory after you pass away unless you take some simple steps.

Here’s how you can prepare your digital life for your survivors:

Apple

The iPhone maker lets you nominate a “ legacy contact ” who can access your Apple account’s data after you die. The company says it’s a secure way to give trusted people access to photos, files and messages. To set it up you’ll need an Apple device with a fairly recent operating system — iPhones and iPads need iOS or iPadOS 15.2 and MacBooks needs macOS Monterey 12.1.

For iPhones, go to settings, tap Sign-in & Security and then Legacy Contact. You can name one or more people, and they don’t need an Apple ID or device.

You’ll have to share an access key with your contact. It can be a digital version sent electronically, or you can print a copy or save it as a screenshot or PDF.

Take note that there are some types of files you won’t be able to pass on — including digital rights-protected music, movies and passwords stored in Apple’s password manager. Legacy contacts can only access a deceased user’s account for three years before Apple deletes the account.

Google

Google takes a different approach with its Inactive Account Manager, which allows you to share your data with someone if it notices that you’ve stopped using your account.

When setting it up, you need to decide how long Google should wait — from three to 18 months — before considering your account inactive. Once that time is up, Google can notify up to 10 people.

You can write a message informing them you’ve stopped using the account, and, optionally, include a link to download your data. You can choose what types of data they can access — including emails, photos, calendar entries and YouTube videos.

There’s also an option to automatically delete your account after three months of inactivity, so your contacts will have to download any data before that deadline.

Facebook and Instagram

Some social media platforms can preserve accounts for people who have died so that friends and family can honor their memories.

When users of Facebook or Instagram die, parent company Meta says it can memorialize the account if it gets a “valid request” from a friend or family member. Requests can be submitted through an online form.

The social media company strongly recommends Facebook users add a legacy contact to look after their memorial accounts. Legacy contacts can do things like respond to new friend requests and update pinned posts, but they can’t read private messages or remove or alter previous posts. You can only choose one person, who also has to have a Facebook account.

You can also ask Facebook or Instagram to delete a deceased user’s account if you’re a close family member or an executor. You’ll need to send in documents like a death certificate.

TikTok

The video-sharing platform says that if a user has died, people can submit a request to memorialize the account through the settings menu. Go to the Report a Problem section, then Account and profile, then Manage account, where you can report a deceased user.

Once an account has been memorialized, it will be labeled “Remembering.” No one will be able to log into the account, which prevents anyone from editing the profile or using the account to post new content or send messages.

X

It’s not possible to nominate a legacy contact on Elon Musk’s social media site. But family members or an authorized person can submit a request to deactivate a deceased user’s account.

Passwords

Besides the major online services, you’ll probably have dozens if not hundreds of other digital accounts that your survivors might need to access. You could just write all your login credentials down in a notebook and put it somewhere safe. But making a physical copy presents its own vulnerabilities. What if you lose track of it? What if someone finds it?

Instead, consider a password manager that has an emergency access feature. Password managers are digital vaults that you can use to store all your credentials. Some, like Keeper,Bitwarden and NordPass, allow users to nominate one or more trusted contacts who can access their keys in case of an emergency such as a death.

But there are a few catches: Those contacts also need to use the same password manager and you might have to pay for the service.

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Is there a tech challenge you need help figuring out? Write to us at onetechtip@ap.org with your questions.

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Pediatric group says doctors should regularly screen kids for reading difficulties

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The Canadian Paediatric Society says doctors should regularly screen children for reading difficulties and dyslexia, calling low literacy a “serious public health concern” that can increase the risk of other problems including anxiety, low self-esteem and behavioural issues, with lifelong consequences.

New guidance issued Wednesday says family doctors, nurses, pediatricians and other medical professionals who care for school-aged kids are in a unique position to help struggling readers access educational and specialty supports, noting that identifying problems early couldhelp kids sooner — when it’s more effective — as well as reveal other possible learning or developmental issues.

The 10 recommendations include regular screening for kids aged four to seven, especially if they belong to groups at higher risk of low literacy, including newcomers to Canada, racialized Canadians and Indigenous Peoples. The society says this can be done in a two-to-three-minute office-based assessment.

Other tips encourage doctors to look for conditions often seen among poor readers such as attention-deficit hyperactivity disorder; to advocate for early literacy training for pediatric and family medicine residents; to liaise with schools on behalf of families seeking help; and to push provincial and territorial education ministries to integrate evidence-based phonics instruction into curriculums, starting in kindergarten.

Dr. Scott McLeod, one of the authors and chair of the society’s mental health and developmental disabilities committee, said a key goal is to catch kids who may be falling through the cracks and to better connect families to resources, including quicker targeted help from schools.

“Collaboration in this area is so key because we need to move away from the silos of: everything educational must exist within the educational portfolio,” McLeod said in an interview from Calgary, where he is a developmental pediatrician at Alberta Children’s Hospital.

“Reading, yes, it’s education, but it’s also health because we know that literacy impacts health. So I think that a statement like this opens the window to say: Yes, parents can come to their health-care provider to get advice, get recommendations, hopefully start a collaboration with school teachers.”

McLeod noted that pediatricians already look for signs of low literacy in young children by way of a commonly used tool known as the Rourke Baby Record, which offers a checklist of key topics, such as nutrition and developmental benchmarks, to cover in a well-child appointment.

But he said questions about reading could be “a standing item” in checkups and he hoped the society’s statement to medical professionals who care for children “enhances their confidence in being a strong advocate for the child” while spurring partnerships with others involved in a child’s life such as teachers and psychologists.

The guidance said pediatricians also play a key role in detecting and monitoring conditions that often coexist with difficulty reading such as attention-deficit hyperactivity disorder, but McLeod noted that getting such specific diagnoses typically involves a referral to a specialist, during which time a child continues to struggle.

He also acknowledged that some schools can be slow to act without a specific diagnosis from a specialist, and even then a child may end up on a wait list for school interventions.

“Evidence-based reading instruction shouldn’t have to wait for some of that access to specialized assessments to occur,” he said.

“My hope is that (by) having an existing statement or document written by the Canadian Paediatric Society … we’re able to skip a few steps or have some of the early interventions present,” he said.

McLeod added that obtaining specific assessments from medical specialists is “definitely beneficial and advantageous” to know where a child is at, “but having that sort of clear, thorough assessment shouldn’t be a barrier to intervention starting.”

McLeod said the society was partly spurred to act by 2022’s “Right to Read Inquiry Report” from the Ontario Human Rights Commission, which made 157 recommendations to address inequities related to reading instruction in that province.

He called the new guidelines “a big reminder” to pediatric providers, family doctors, school teachers and psychologists of the importance of literacy.

“Early identification of reading difficulty can truly change the trajectory of a child’s life.”

This report by The Canadian Press was first published Oct. 23, 2024.

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