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Pfizer/BioNTech COVID-19 vaccine could ship to Canada within 24 hours of approval, exec says – CBC.ca

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Canada is well-positioned to approve Pfizer and BioNTech’s COVID-19 vaccine soon — and it could be delivered to the country very quickly after that, a BioNTech executive says.

“If I use the U.K. as an example, we got approval at 1:00 am in the morning. We approved [the] release of the vaccine and shipped it within 24 hours,” said Sean Marett, the chief business and chief commercial officer of Germany’s BioNTech, which partnered with the U.S.-based Pfizer to develop one of the world’s most promising COVID-19 vaccine candidates.

“Certainly from the discussions that we’ve had, Canada is in a good position to approve the vaccine shortly,” Marett told CBC Chief Political Correspondent Rosemary Barton on Sunday.

The Pfizer/BioNTech product — which was recently greenlit in the U.K. for emergency use —  could receive approval from Health Canada as soon as this coming week. Health regulators are currently reviewing three other vaccines produced by Moderna, AstraZeneca and Jannsen.

“Upon approval, we then release the vaccine and then it is shipped. We’ve already produced the vaccine and reserved doses for Canada,” Marett said on Rosemary Barton Live.

Regulatory approval is a key step before the finer details of the federal government’s rollout plan can be set in motion.

“We are negotiating for more precise delivery dates pending Health Canada approval,” Procurement Minister Anita Anand told CBC’s Vassy Kapelos earlier this week. “It’s for that reason that we’re putting the logistics systems in place so that there is no time lost between approval and then distribution to the provinces and territories.”

Rollout the ‘biological equivalent of a moon landing’

Marett called the distribution plan for the vaccine the “biological equivalent of a moon landing.”

“You’ve got to get everything exactly right, and that, of course, includes timings,” Marett said, when asked about exact delivery dates. “These things tend to … move around [for] a few days. But so far, from our experience with one country, the United Kingdom, we’ve seen things move pretty smoothly.”

WATCH | Welsh health minister talks lessons for Canada as U.K. prepares to vaccinate:

Welsh Minister of Health Vaughan Gething talks about lessons for Canada as Wales prepares to start COVID-19 vaccinations in 48 hours. 7:18

On Friday, Anand announced a contract with FedEx Express Canada to support the shipment of most vaccines across the country. 

But the Pfizer/BioNTech candidate will be delivered by the pharmaceutical company directly because the product needs to be kept at approximately -70 C to remain stable. Ottawa says it’s already secured enough freezers to store up to 33.5 million units of the vaccine.

Marett said transporting and housing products in sub-zero temperatures is a process that’s been “well mapped out.”

“Together with Pfizer, we’ve designed a storage box … in which the vaccine arrives. You can use that as a -70 freezer. You can open the box twice a day and take vaccine out as long as you re-ice it for up to 15 days,” he explained.

Canada has signed a deal with Pfizer and BioNTech to pre-order 20 million doses of the vaccine, with an option to buy 56 million more in the months ahead. Pfizer says the shots are 95 per cent effective based on Phase 3 clinical trial results.

Marett said his company was “completely stunned” by those findings, considering the vaccine was developed in a matter of months as opposed to years. 

“Ninety-five per cent efficacy, as defined by do you get [COVID-19] symptoms or not … is, in our view, a startling result,” he said.

BioNtech executive Sean Marett says his company’s COVID-19 vaccine candidate will be shipped in special freezer boxes, straight to immunization centres around the world. (Dado Ruvic/Reuters)

PM to discuss rollout with premiers Thursday

Public health officials say that if all goes well, six million doses of the Pfizer/BioNTech and Moderna vaccines are slated to arrive in Canada within the first three months of 2021. Both vaccines must be administered twice, meaning three million Canadians from several priority groups will be among the first to get a jab.

Some provincial leaders, however, have conflicting views over whether vaccines should be doled out on a per-capita basis or whether they’ll be disseminated based on the coronavirus caseload in a given region.

Newfoundland and Labrador Premier Andrew Furey told Barton last week that the safest way to distribute vaccines would be based on population, once the country’s most vulnerable are inoculated. Manitoba’s Brian Pallister said Thursday that a per-capita plan could hurt his hard-hit province.  

“Many provinces have advocated for a per-capita sharing of the vaccines,” federal Intergovernmental Affairs Minister Dominic LeBlanc said in a separate interview on Sunday. “But [that] will be finalized, we hope, in the conversations that the prime minister will have with premiers this coming week.”

WATCH | Minister LeBlanc discusses upcoming first ministers’ meeting:

Health Canada has yet to approve a vaccine for COVID-19. But Minister of Intergovernmental Affairs Dominic LeBlanc, who also chairs the federal cabinet committee on COVID-19 response, says he expects those approvals to come shortly. 9:54

Prime Minister Justin Trudeau will meet with premiers on Thursday to discuss Canada’s shared efforts to fight the COVID-19 pandemic and co-ordinate the country’s inoculation response.

Maj.-Gen. Dany Fortin, the former NATO commander now leading vaccine logistics and operations for the Public Health Agency of Canada, said Friday that every province has now identified specific sites where shots will be received.

On Monday, dry runs are expected to be carried out in each province to ensure that those involved in the rollout process are prepared to handle the “very unique requirements” of an ultra-cold vaccine, Fortin said.

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Brian White scores second-half goal, earns Whitecaps 1-1 draw with Dynamo

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HOUSTON (AP) — Brian White scored in the second half to rally the Vancouver Whitecaps to a 1-1 draw with the Houston Dynamo on Wednesday night.

Houston (12-9-8) took a 1-0 lead into halftime after Ezequiel Ponce scored on a penalty kick in the seventh minute of stoppage time. Ponce’s third goal this season came after Amine Bassi drew a foul on Whitecaps midfielder Pedro Vite following a video review. It was Ponce’s sixth career appearance, all starts.

Vancouver (13-8-7) scored the equalizer in the 73rd minute when White, who entered in the 60th, used assists from Fafá Picault and Ryan Gauld to find the net for the 13th time this season. Picault’s assist was his fifth, matching his career high for a single season. Gauld’s assist gives him a career-best 13 on the season.

Yohei Takaoka, who had clean sheets in his last three starts, finished with one save in goal for the Whitecaps.

Steve Clark saved three shots for the Dynamo, who remain one point behind Vancouver in the Western Conference standings.

Houston, which was coming off a 4-1 victory over Real Salt Lake, has allowed just 33 goals this season.

Vancouver — 6-2-2 in its last 10 matches overall — leads the all-time series 10-9-6.

The Whitecaps remain on the road to play the Los Angeles Galaxy on Saturday. The Dynamo travel to play Austin FC on Saturday.

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AP MLS:

The Canadian Press. All rights reserved.



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First career goals by Tom Pearce, Nathan Saliba rally Montreal to 2-2 draw with Revolution

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FOXBOROUGH, Mass. (AP) — Tom Pearce and Nathan Saliba scored in the second half — the first goals of their careers — and CF Montreal rallied for a 2-2 draw with the New England Revolution on Wednesday night.

“In the second half, the guys came out a little more ambitious and above all, more connected,” Montreal head coach Laurent Courtois said. “It was a great second half of resilience and fighting spirit. Nathan and Sam were impressive.

“Impressive in covering the gaps and compensating for the teammates, and the individual defending – yes it’s true, it is a lot of weight on their shoulders, but that’s the job.”

New England (8-16-4) jumped out to a 1-0 lead in the 24th minute on Bobby Wood’s third goal of the season. Teenage defender Peyton Miller notched his first assist in his fourth career start and sixth appearance and Carles Gil picked up his ninth of the season. Peyton, at 16 years, 315 days old, is the eighth youngest player in league history to record his first assist.

The Revolution took a two-goal lead in the 35th minute and held it through halftime when 19-year-old Esmir Bajraktarevic took a pass from Gil and scored his third goal of the season and career in his first full season in the league. It was the 73rd regular-season assist in Gil’s career, tying him with Steve Ralston for the most in club history.

Montreal (7-12-10) pulled within a goal in the 54th minute when Pearce scored off a free kick after defender George Campbell drew a foul on New England’s Mark-Anthony Kaye. It was the first goal for Pearce in his third career start and fourth appearance.

“Playoffs are the goal. Maybe it wasn’t in the best form, but in the end, we are picking up a point,” Pearce said. “We came into this game confident, ready to play our own game. Everyone tries their best, whenever the players are called on, we are always ready, and we are always giving it our best.”

Montreal scored the equalizer in the 68th minute on the first career goal by Saliba, a 20-year-old midfielder. Saliba has made 34 starts and 48 appearances with Montreal in his two seasons in the league. Campbell snagged his second assist of the season and the third of his career.

“It’s an incredible feeling, it’s a goal I’ve been waiting for a long time. I’m extremely happy that I was able to score it and that it can help the team take this important point on the road,” Saliba said. “Pearce’s first goal gave us really good momentum and we kept up the pressure to go for a second goal. We got more solid defensively, and we came back ready after halftime, to push for these 3 points.”

Aljaz Ivacic finished with four saves in goal for the Revolution.

Jonathan Sirois stopped four shots for Montreal.

New England beat Montreal 5-0 on the road on Aug. 24.

New England leads the all-time series 16-13-4. Montreal improves to 5-8-2 on the road against the Revs.

The Revolution travel to take on Charlotte FC on Saturday. Montreal returns home to host the Chicago Fire on Saturday.

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AP MLS:

The Canadian Press. All rights reserved.



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Adolis García’s home run backs Cody Bradford as Rangers beat Blue Jays 2-0

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ARLINGTON, Texas (AP) — Adolis García hit a two-run home run in the sixth inning, Cody Bradford pitched seven strong innings after the worst start of his career, and the Texas Rangers beat the Toronto Blue Jays 2-0 on Wednesday night.

The win kept the defending World Series-champion Rangers alive in the AL West race, trailing first-place Houston by 10 games with 10 to play.

García launched an inside sinker over the left-field wall off Toronto starter Bowden Francis (8-5) after Wyatt Langford singled.

“He swings hard, he swings a lot,” Francis said of García. “I guess the velo was dropping during that time.”

Bradford (6-3) allowed five hits and no walks while striking out six.

The seven shutout innings are the most in a game during his two-year career. He was knocked out of his previous start after allowing career highs in hits (nine), runs (eight) and homers (three) in 3 2/3 innings in a 14-4 loss at Arizona.

“Throughout the week, you’ve got to try and digest what happened, see where I can make adjustments, whether it was just game plan went wrong or just poor execution, or a little bit of both,” Bradford said. “Then you flush it.”

Bradford was perfect through four innings before Alejandro Kirk opened the fifth with a smash back to the mound that caromed off Bradford’s left foot and rolled into right field for a single. It extended Kirk’s hitting streak to a career-high 12 games.

Spencer Horwitz’s double to left-center put runners on second and third with no outs before Bradford retired the next three batters.

Blue Jays manager John Schneider credited Bradford’s “deceptive fastball.”

“When you’re throwing 89, 92, you’ve got to have pretty good deception with that at this level,” Schneider said. “Kept us off balance.”

Kirby Yates pitched a perfect ninth inning for his 31st save in 32 opportunities.

Francis, who took no-hitters into the ninth inning in two of his previous four starts, allowed a double to Marcus Semien, the Rangers’ first hitter of the game. He gave up five hits and one walk in six innings.

Francis has a 1.96 ERA in nine starts with 54 strikeouts and seven walks since being moved back into the starting rotation in late July.

“I don’t even want to get complacent, on cruise control,” Francis said. “Just keep attacking.”

TRAINER’S ROOM

Blue Jays: SS Bo Bichette was a late scratch with a right middle finger contusion suffered during infield practice. Schneider said the team will get back x-rays on Thursday. Bichette was activated Tuesday following a calf injury and played for the first time in two months, going 2 for 5 with one RBI at the plate. … INF Will Wagner (left knee inflammation) will have the knee scoped on Thursday. Schneider said Wagner should be ready to start spring training. Wagner, son of former major leaguer Billy Wagner, was acquired from Houston at the trade deadline.

UP NEXT

Rangers rookie RHP Kumar Rocker (0-0, 2.25 ERA) will make his home debut against Blue Jays RHP Kevin Gausman (12-11, 4.02) in the series finale. Rocker allowed one run in four innings at Seattle last Thursday in his major league debut.

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AP MLB:

The Canadian Press. All rights reserved.



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