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Politics, Not Science, May Be Behind Suspensions Of AstraZeneca’s Covid Vaccine – Forbes

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Multiple experts say that the drug company’s vaccine is being unfairly targeted by EU countries, hindering plans to roll it out worldwide at a critical time. 


On Monday, Germany, France, Italy and Spain became the latest countries to halt the administration of the Covid-19 vaccine developed by Oxford University and pharmaceutical giant AstraZeneca. These countries are following in the footsteps of Denmark, Norway, Ireland, the Netherlands and Thailand, who have also suspended use of the vaccine, which has yet to be authorized for use in the United States. 

Ostensibly, these suspensions are due to a cluster of cases in which the vaccine may have increased risk of blood clotting. But multiple experts say that the vaccine is safe and that suspensions hinder efforts to rollout vaccines worldwide. Others worry the vaccine is being put on hold for political, rather than scientific, reasons. This is especially a concern given that demand for vaccines currently outstrip supply as Covid-19 cases continue to spike across Europe

Several countries have reported a possible increase in blood clotting among patients who received AstraZeneca’s vaccine. There have been 37 such reports among the 17 million people vaccinated across the U.K. and EU, and preliminary reports suggest one person each in Italy, Austria and Denmark died due to blood clots after getting the AstraZeneca vaccine. The European Medicine Agency’s (EMA) safety committee cautions, however, that none of those deaths were actually linked to the vaccine. The committee further noted that several people who got blood clots were middle aged, when such clots are more common, and that blood clots aren’t particularly rare in the general population. AstraZeneca noted in a statement that the number of blood clots are actually “much lower than would be expected to occur naturally in a general population of this size.”

Davey Smith, an infectious disease specialist at the University of California San Diego, is baffled by governments’ decisions to suspend use of AstraZeneca’s vaccine. “I’ve seen no data to see why they are stopping,” he says, adding, “People are going to get blood clots, because they would have gotten them with or without the vaccine.”

Jennifer Nuzzo, an epidemiologist at the Johns Hopkins Center for Health Security, also expressed surprise at these governments’ moves. “Pausing to review data is fine,” she says. “But what pausing means is losing ground against protecting people against a deadly pandemic, so there is something lost with that.” 

Once considered to be the leader in the race for a Covid-19 vaccine, AstraZeneca has ended up facing more hurdles than its competitors. Problems started last September, when global trials of the vaccine were paused due to a patient experiencing a severe illness. The trial soon resumed, but two months later the company revealed a blunder: in the U.K. trials run by Oxford, participants had accidentally been given half-doses of the vaccine, a mistake that shook the faith of regulators in the U.S., who now expect final clinical trial data from AstraZeneca in April. 

Still, data in ongoing international trials proved more promising: the vaccine was 82% effective at preventing Covid-19 after two doses, and 100% effective at preventing hospitalizations and death. The strong showing led to emergency authorizations for the vaccine in the United Kingdom in December, with authorizations from the European Union and World Health Organization in early 2021. So far, doses of the vaccine have been administered to 17 million patients in Europe. 

The AstraZeneca vaccine uses a DNA component that instructs cells to produce the same proteins that are found on parts of the virus that causes Covid-19. These proteins train the body’s immune system to produce antibodies against it. It’s delivered into people’s systems using a modified version of a virus for the common cold that infects chimpanzees, but can’t make people sick. One advantage it has over vaccines produced by Pfizer and Moderna is that it can be refrigerated rather than frozen and is more durable for transportation. This makes it of particular importance in distributing the vaccine worldwide. “I think the stakes with AstraZeneca is particularly high,” says Nuzzo, “because this was anticipated to be a vaccine that much of the world will ultimately come to depend on for their vaccination efforts.” 

“In the end it could be very harmful for the whole vaccine rollout in general.”

So why are so many European countries taking the seemingly radical step of halting administration outright? In a report published earlier this month by Barclays, the investment firm looked at some of AstraZeneca’s previous regulatory issues and suggested that “most of the controversy that has been had a political genesis rather than a scientific one.” In noting some of the differences between what EMA had approved for the vaccine versus how some European countries had authorized use of the vaccine, the report goes on to speculate that “authorities in certain geographies may have been looking for someone to blame for an initially frustrating rollout.” Public health experts speculated to Forbes that similar reasons may have fueled the recent suspensions. An interesting contrast can be seen in Canada, which is reportedly preparing to expand its authorization of the vaccine to senior citizens, when it had previously not been recommended for adults over 65.

Justified or not, halting administration of AstraZeneca’s vaccine risks exacerbating an already strong reluctance to get vaccinated. A recent policy brief from the European Centre for Disease Prevention and Control found that less than half of people in the E.U. believe that Covid-19 vaccines are safe. For this reason, Nuzzo urges public health agencies to be transparent throughout the process of evaluating the vaccine during its suspension. “Sometimes what happens is countries make this announcement, and then they’re kind of silent for weeks,” she says. “And really in that void, a lot of misinformation can rise to fill what is lack of communication.”

Smith agrees, and adds that suspending administration of the vaccine is a risk in the greater fight against the pandemic. “In the end it could be very harmful for the whole vaccine rollout in general,” he says. Based on the reported data, he says he doesn’t see a justification for governments suspending the vaccine, commenting that “if they do have data, and if they’re making decisions based on data that nobody has, then it’s a transparency problem.”

So far, suspensions among E.U. nations aren’t expected to halt distribution elsewhere. Earlier this month, the COVID-19 Vaccines Global Access (COVAX), a public-private vaccine initiative to distribute vaccines to emerging economies, began distributing doses of AstraZeneca’s vaccine to India, Ghana and Cote D’Ivorie. More are expected to follow, with 237 million doses allocated to over 130 countries this month. “Safety is our paramount concern: we know that national authorities and the WHO are monitoring the situation closely and the COVAX Facility will be following their guidance and recommendation,” a spokesperson for Gavi, the private-public partnership responsible for distributing vaccines for COVAX told Forbes. “Currently no causal link has been established between the vaccine and thromboembolic events in individuals, and the vaccine remains an important and effective public health tool in the fight against this pandemic.”

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‘Disgraceful:’ N.S. Tory leader slams school’s request that military remove uniform

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HALIFAX – Nova Scotia Premier Tim Houston says it’s “disgraceful and demeaning” that a Halifax-area school would request that service members not wear military uniforms to its Remembrance Day ceremony.

Houston’s comments were part of a chorus of criticism levelled at the school — Sackville Heights Elementary — whose administration decided to back away from the plan after the outcry.

A November newsletter from the school in Middle Sackville, N.S., invited Armed Forces members to attend its ceremony but asked that all attendees arrive in civilian attire to “maintain a welcoming environment for all.”

Houston, who is currently running for re-election, accused the school’s leaders of “disgracing themselves while demeaning the people who protect our country” in a post on the social media platform X Thursday night.

“If the people behind this decision had a shred of the courage that our veterans have, this cowardly and insulting idea would have been rejected immediately,” Houston’s post read. There were also several calls for resignations within the school’s administration attached to Houston’s post.

In an email to families Thursday night, the school’s principal, Rachael Webster, apologized and welcomed military family members to attend “in the attire that makes them most comfortable.”

“I recognize this request has caused harm and I am deeply sorry,” Webster’s email read, adding later that the school has the “utmost respect for what the uniform represents.”

Webster said the initial request was out of concern for some students who come from countries experiencing conflict and who she said expressed discomfort with images of war, including military uniforms.

Her email said any students who have concerns about seeing Armed Forces members in uniform can be accommodated in a way that makes them feel safe, but she provided no further details in the message.

Webster did not immediately respond to a request for comment.

At a news conference Friday, Houston said he’s glad the initial request was reversed but said he is still concerned.

“I can’t actually fathom how a decision like that was made,” Houston told reporters Friday, adding that he grew up moving between military bases around the country while his father was in the Armed Forces.

“My story of growing up in a military family is not unique in our province. The tradition of service is something so many of us share,” he said.

“Saying ‘lest we forget’ is a solemn promise to the fallen. It’s our commitment to those that continue to serve and our commitment that we will pass on our respects to the next generation.”

Liberal Leader Zach Churchill also said he’s happy with the school’s decision to allow uniformed Armed Forces members to attend the ceremony, but he said he didn’t think it was fair to question the intentions of those behind the original decision.

“We need to have them (uniforms) on display at Remembrance Day,” he said. “Not only are we celebrating (veterans) … we’re also commemorating our dead who gave the greatest sacrifice for our country and for the freedoms we have.”

NDP Leader Claudia Chender said that while Remembrance Day is an important occasion to honour veterans and current service members’ sacrifices, she said she hopes Houston wasn’t taking advantage of the decision to “play politics with this solemn occasion for his own political gain.”

“I hope Tim Houston reached out to the principal of the school before making a public statement,” she said in a statement.

This report by The Canadian Press was first published Nov. 8, 2024.

The Canadian Press. All rights reserved.

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Saskatchewan NDP’s Beck holds first caucus meeting after election, outlines plans

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REGINA – Saskatchewan Opposition NDP Leader Carla Beck says she wants to prove to residents her party is the government in waiting as she heads into the incoming legislative session.

Beck held her first caucus meeting with 27 members, nearly double than what she had before the Oct. 28 election but short of the 31 required to form a majority in the 61-seat legislature.

She says her priorities will be health care and cost-of-living issues.

Beck says people need affordability help right now and will press Premier Scott Moe’s Saskatchewan Party government to cut the gas tax and the provincial sales tax on children’s clothing and some grocery items.

Beck’s NDP is Saskatchewan’s largest Opposition in nearly two decades after sweeping Regina and winning all but one seat in Saskatoon.

The Saskatchewan Party won 34 seats, retaining its hold on all of the rural ridings and smaller cities.

This report by The Canadian Press was first published Nov. 8, 2024.

The Canadian Press. All rights reserved.

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Nova Scotia election: Liberals say province’s immigration levels are too high

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HALIFAX – Nova Scotia‘s growing population was the subject of debate on Day 12 of the provincial election campaign, with Liberal Leader Zach Churchill arguing immigration levels must be reduced until the province can provide enough housing and health-care services.

Churchill said Thursday a plan by the incumbent Progressive Conservatives to double the province’s population to two million people by the year 2060 is unrealistic and unsustainable.

“That’s a big leap and it’s making life harder for people who live here, (including ) young people looking for a place to live and seniors looking to downsize,” he told a news conference at his campaign headquarters in Halifax.

Anticipating that his call for less immigration might provoke protests from the immigrant community, Churchill was careful to note that he is among the third generation of a family that moved to Nova Scotia from Lebanon.

“I know the value of immigration, the importance of it to our province. We have been built on the backs of an immigrant population. But we just need to do it in a responsible way.”

The Liberal leader said Tim Houston’s Tories, who are seeking a second term in office, have made a mistake by exceeding immigration targets set by the province’s Department of Labour and Immigration. Churchill said a Liberal government would abide by the department’s targets.

In the most recent fiscal year, the government welcomed almost 12,000 immigrants through its nominee program, exceeding the department’s limit by more than 4,000, he said. The numbers aren’t huge, but the increase won’t help ease the province’s shortages in housing and doctors, and the increased strain on its infrastructure, including roads, schools and cellphone networks, Churchill said.

“(The Immigration Department) has done the hard work on this,” he said. “They know where the labour gaps are, and they know what growth is sustainable.”

In response, Houston said his commitment to double the population was a “stretch goal.” And he said the province had long struggled with a declining population before that trend was recently reversed.

“The only immigration that can come into this province at this time is if they are a skilled trade worker or a health-care worker,” Houston said. “The population has grown by two per cent a year, actually quite similar growth to what we experienced under the Liberal government before us.”

Still, Houston said he’s heard Nova Scotians’ concerns about population growth, and he then pivoted to criticize Prime Minister Justin Trudeau for trying to send 6,000 asylum seekers to Nova Scotia, an assertion the federal government has denied.

Churchill said Houston’s claim about asylum seekers was shameful.

“It’s smoke and mirrors,” the Liberal leader said. “He is overshooting his own department’s numbers for sustainable population growth and yet he is trying to blame this on asylum seekers … who aren’t even here.”

In September, federal Immigration Minister Marc Miller said there is no plan to send any asylum seekers to the province without compensation or the consent of the premier. He said the 6,000 number was an “aspirational” figure based on models that reflect each province’s population.

In Halifax, NDP Leader Claudia Chender said it’s clear Nova Scotia needs more doctors, nurses and skilled trades people.

“Immigration has been and always will be a part of the Nova Scotia story, but we need to build as we grow,” Chender said. “This is why we have been pushing the Houston government to build more affordable housing.”

Chender was in a Halifax cafe on Thursday when she promised her party would remove the province’s portion of the harmonized sales tax from all grocery, cellphone and internet bills if elected to govern on Nov. 26. The tax would also be removed from the sale and installation of heat pumps.

“Our focus is on helping people to afford their lives,” Chender told reporters. “We know there are certain things that you can’t live without: food, internet and a phone …. So we know this will have the single biggest impact.”

The party estimates the measure would save the average Nova Scotia family about $1,300 a year.

“That’s a lot more than a one or two per cent HST cut,” Chender said, referring to the Progressive Conservative pledge to reduce the tax by one percentage point and the Liberal promise to trim it by two percentage points.

Elsewhere on the campaign trail, Houston announced that a Progressive Conservative government would make parking free at all Nova Scotia hospitals and health-care centres. The promise was also made by the Liberals in their election platform released Monday.

“Free parking may not seem like a big deal to some, but … the parking, especially for people working at the facilities, can add up to hundreds of dollars,” the premier told a news conference at his campaign headquarters in Halifax.

This report by The Canadian Press was first published Nov. 7, 2024.

— With files from Keith Doucette in Halifax

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