Health
Regular Cannabis Use Linked to Structural Changes in Heart – MD Magazine
Results of a new study from the Queen Mary University of London is establishing a potential link between cannabis use and structural changes to the heart.
Using MRI images from more than 3000 people, including 152 current or former cannabis users, investigators found regular use of cannabis was linked to enlargement of the left ventricle and early signs of impaired heart function.
With the legalization and decriminalization of cannabis becoming increasingly common throughout the world, investigators sought to evaluate potential associates between cannabis use and cardiac function and structure through MRI images of 3407 UK Biobank participants. Most of the participants rarely or never used cannabis, while 47 were current regular users, and 105 had used it regularly but more than 5 years ago—regular use was defined as daily or weekly use.
The mean age of the study population was 62 years and 55% were female. Investigators pointed out participants who were current users were more likely to be younger, male, current tobacco smokers, and have greater levels of social deprivation but were less likely to be on antihypertensive medication, compared to the non-users or previous user groups.
In analyses adjusted for factors including age, sex, BMI, diabetes, smoking, and alcohol consumption, regular cannabis use was associated with larger indexed left ventricular end-diastolic (+5.31 ml/m2, 95% CI: 1.4 – 9.3 mls/m2, P=0.008), end-systolic volumes (+3.3 mls/m2, 95% CI: 0.78 – 5.83 mls/m2, P=0.010), and impaired myocardial global circumferential strain (-0.78, 95% CI: -1.47 – -0.09, P=0.026) compared to non-users. No differences were noted between left ventricular myocardial mass, ejection fraction and stroke volume, or right ventricular, left atrial and right atrial parameters. Additionally, previous users had parameters similar to those of participants classified as rare or non-users.
While investigators noted the study, which they suggest is the first to report alterations in cardiac structure and function associated with recreational cannabis use, indicates cannabis use was associated with potentially adverse changes to heart structure they also pointed out their study had multiple limitations. Limitations of the study included being restricted to mostly (96%) Caucasians and reliance on self-reported cannabis use.
“Our findings are not conclusive but the research took place against a backdrop of decriminalization and legalization of recreational cannabis use in many countries,” said lead investigator Mohammed Khanji, MBBCh, PhD, senior clinical lecturer at Queen Mary University of London. “We urgently need systematic research to identify the long-term implications of regular consumption of cannabis on the heart and blood vessels.”
This study, titled “Association between recreational cannabis use and cardiac structure and function,” was published in JACC Cardiovascular Imaging.
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Alberta Health Services (AHS) has confirmed a case of measles in Edmonton, and is advising the public that the individual was out in public while infectious.
Measles is an extremely contagious disease that is spread easily through the air, and can only be prevented through immunization.
AHS says individuals who were in the following locations during the specified dates and times, may have been exposed to measles.
- April 16
- Edmonton International Airport, international arrivals and baggage claim area — between 3:20 p.m. and 6 p.m.
- April 20
- Stollery Children’s Hospital Emergency Department — between 5 a.m. to 3 p.m.
- April 22
- 66th Medical Clinic (13635 66 St NW Edmonton) — between 12:15 p.m. to 3:30 p.m.
- Pharmacy 66 (13637 66 St NW Edmonton) — between 12:15 p.m. to 3:30 p.m.
- April 23
- Stollery Children’s Hospital Emergency Department — between 4:40 a.m. to 9:33 a.m.
AHS says anyone who attended those locations during those times is at risk of developing measles if they’ve not had two documented doses of measles-containing vaccine.
Those who have not had two doses, who are pregnant, under one year of age, or have a weakened immune system are at greatest risk of getting measles and should contact Health Link at 1-877-720-0707.
Symptoms
Symptoms of measles include a fever of 38.3° C or higher, cough, runny nose, and/or red eyes, a red blotchy rash that appears three to seven days after fever starts, beginning behind the ears and on the face and spreading down the body and then to the arms and legs.
If you have any of these symptoms stay home and call Health Link.
In Alberta, measles vaccine is offered, free of charge, through Alberta’s publicly funded immunization program. Children in Alberta typically receive their first dose of measles vaccine at 12 months of age, and their second dose at 18 months of age.
Health
U.S. tightens rules for dairy cows a day after bird flu virus fragments found in pasteurized milk samples – Toronto Star
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Infected cows were already prohibited from being transported out of state, but that was based on the physical characteristics of the milk, which looks curdled when a cow is infected, or a cow has decreased lactation or low appetite, both symptoms of infection.
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U.S. growth slowed sharply last quarter to 1.6% pace, reflecting an economy pressured by high rates – BNN Bloomberg
Plot twist: Kings steal home ice from Edmonton Oilers in OT stunner – Edmonton Journal
Giant prehistoric salmon had tusk-like teeth for defence, building nests: study – CP24
Silver investment demand jumped 12% in 2019
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