Connect with us

Health

Vaping-associated lung injuries can be attributed to vitamin E acetate, CDC says – The Verge

Published

 on


The outbreak of vaping-associated lung injuries this summer and fall can officially be attributed to vitamin E acetate in THC-containing vaping products, the Centers for Disease Control said today. The new confirmation of the link between the chemical and the injuries came after a new study found it in nearly all of the lung fluid samples from a new set of patients.

As of December 17, 2,506 people have been hospitalized with e-cigarette, or vaping, product use-associated lung injury (EVALI), according to the CDC. There have been 54 deaths. The injuries started increasing in June before peaking in September, new CDC data indicates, and the number of visits to emergency departments for vaping-associated injuries have been declining since.

“It is clear that the outbreak represented a new phenomenon,” said Anne Schuchat, principal deputy director of the CDC, during a press conference. “It’s not a recognition of a common syndrome that had evaded our attention.”

Vitamin E acetate was first identified as a key focus of a statewide investigation in New York in September. It was later described as a chemical of concern by the CDC in November, after it was found in every one of a set of 29 lung fluid samples tested by the agency. Investigators also found that most patients with EVALI reported using THC-containing vaping products before their injury. Product testing by the Food and Drug Administration has found many of those products are contaminated with the chemical. It hasn’t been found in nicotine-only vaping products.

In the new study, published today in the New England Journal of Medicine, clinicians collected lung fluid samples from 51 patients with either confirmed or probable EVALI. Vitamin E acetate was found in 48 of the samples — 94 percent. The majority of the patients also had THC in their lung fluid samples. Of the 11 patients who said they had not used THC products in the 90 days before their injury, nine had detectable levels of THC.

This set of patient samples was also compared to those from a group of 99 healthy people without EVALI, who were either e-cigarette smokers (with nicotine only), traditional cigarette smokers, or non-smokers. None of the samples from healthy people had vitamin E acetate, including those from the e-cigarette smokers.

The combination of this new data, along with previous reports and product analysis, allowed the CDC to conclude that the chemical was responsible for the outbreak. “The very large increase in cases is attributable to what was happening in this past year in the supply, with vitamin E acetate diluting or tainting THC products,” Schuchat said. In Minnesota, for example, THC-containing products from 2018 did not contain vitamin E acetate, but products from 2019 did.

Vitamin E acetate is a safe dietary supplement and ingredient in topical lotions and creams, but when it’s inhaled, it may interfere with proper lung function. Heating the chemical in a vaporizer can also cause it to break down into a compound called ketene, which can irritate the lungs. More studies are underway to figure out how vitamin E acetate might cause the type of damage seen in EVALI patients. “We don’t have to hold our breath for those results, but they’ll be helpful for us to go a little deeper in understanding the problem,” Schuchat said.

She stressed, though, that there may be more than one chemical causing these injuries. Not every patient with EVALI reported using THC-containing products, and not every tested product associated with an injury contained vitamin E acetate. “This does not mean there are not other substances in e-cigarettes or vaping products that have or are capable of causing lung injury,” she said.

Let’s block ads! (Why?)



Source link

Continue Reading

Health

Polio virus found in New York City wastewater, suggesting local transmission – CBC News

Published

 on


Health officials identified the virus that causes polio in New York City’s wastewater, suggesting local transmission of the virus, state authorities said on Friday, urging unvaccinated New Yorkers to get vaccinated.

“The NYC Heath Department and the New York State Department of Health have identified poliovirus in sewage in NYC, 
suggesting local transmission of the virus,” the city’s health department said in a statement on Friday.

“Polio can lead to paralysis and even death. We urge unvaccinated New Yorkers to get vaccinated now.”

The identification comes weeks after a case of polio in an adult was made public on July 21 in Rockland County, marking the nation’s first confirmed case in nearly 10 years.

Earlier this month, health officials said the virus was found in wastewater in the New York City suburb a month before health officials there announced the Rockland County case.

The U.S. Centers for Disease Control and Prevention (CDC) said at the time that it was not clear whether the virus was actively spreading in New York or elsewhere in the United States.

Evidence of virus in London

There is no cure for polio, which can cause irreversible paralysis in some cases, but it can be prevented by a vaccine made available in 1955.

New York officials have said they are opening vaccine clinics to help unvaccinated residents get their shots. 

Inactivated polio vaccine (IPV) is the only polio vaccine that has been given in the United States since 2000, according to the CDC. It is given by shot in the leg or arm, depending on the patient’s age.

On Wednesday, British health authorities announced they will offer a polio booster dose to children aged one to nine in London, after finding evidence the virus has been spreading in multiple regions of the capital. Britain’s Health Security Agency said polio virus samples were found in sewage water from eight boroughs of London, but there were no confirmed infections.

Polio is often asymptomatic and people can transmit the virus even when they do not appear sick. But it can produce 
mild, flu-like symptoms that can take as long as 30 days to appear, officials said.

It can strike at any age but the majority of those affected are children aged three and younger. 

Adblock test (Why?)



Source link

Continue Reading

Health

Monkeypox: gov’t has no plans to call public health emergency – CTV News

Published

 on


OTTAWA –

Canada’s chief public health officer Dr. Theresa Tam says there are no plans at the moment to declare monkeypox a public health emergency.

While the World Health Organization and the United States have both recently done so, Tam said there is little benefit to declaring a federal public health emergency in Canada, because of the structure of regional and provincial public health authorities.

She said a federal emergency declaration would involve the Emergencies Act — which hasn’t even been invoked to address the nearly two-and-a-half-year COVID-19 pandemic in Canada. Tam said thus far, Canada has already been able to mobilize vaccines, therapeutics, and funding to tackle monkeypox.

Tam also said local and provincial authorities have more flexibility, and have been able to respond to the rise in monkeypox cases. Local and provincial authorities could also decide to declare the virus a public health emergency at those levels, as many did with COVID-19.

“To date our discussions have focused on testing, working with community organizations to raise awareness on ways to limit spread the virus, and deployment of the Imvamune vaccine and therapeutics,” Tam said. “As the global monkeypox outbreak continues to be a serious concern, focusing efforts on the impacted communities in Canada and worldwide, including with vaccinations, we have an opportunity to contain the spread.”

To day, approximately 99,000 doses of Imvamune have been deployed to the provinces and territories, and more than 50,000 people have been vaccinated, Tam said.

Canada’s Deputy Chief Public Health Officer Dr. Howard Njoo said the approach continues to be vaccinating higher risk communities first, and there are currently enough doses to do so.

Tam says there have been approximately 31,000 cases of monkeypox reported globally, with 1,059 in Canada, mostly in Ontario.

While cases of the virus first started popping up in Quebec, Ontario has since surpassed it in its number of infections.

To date, there have been 28 hospitalizations — two in intensive care — from monkeypox in Canada, and no deaths. Tam said it’s too soon to tell whether the number of cases has plateaued in Canada.

Adblock test (Why?)



Source link

Continue Reading

Health

COVID-19 vaccine side-effects less likely in pregnant people, says study – CP24

Published

 on


Pregnant people experienced lower rates of side-effects from the COVID-19 vaccine than their counterparts who weren’t pregnant, a new Canadian study suggests.

The Canadian National Vaccine Safety Network collected data from 191,360 vaccinated women aged 15 to 49 between December 2020 and November 2021. The researchers asked participants to report “significant health events” that were serious enough to make them miss school or work, seek medical attention or disrupt their routines.

Of 5,597 pregnant participants, four per cent reported a significant health event within seven days of receiving their first dose of an mRNA vaccine, and 7.3 per cent of 3,108 pregnant respondents said they had side-effects from their second shots.

Among those who weren’t pregnant, 6.3 per cent of 174,765 respondents reported a significant health event after dose one, and 11.3 per cent of 10,254 participants said they felt sick after dose two.

“One of the things that was really striking was that the rates of these events happening in pregnant people was lower than the rates happening in non-pregnant people at the same age,” said Manish Sadarangani, lead author of the paper published in the Lancet Infectious Diseases journal on Thursday. “It’s very reassuring around the safety of COVID vaccines and pregnancy.”

Studies on other vaccines have found that pregnant people experience side-effects at roughly the same rate as those who aren’t pregnant or even slightly higher, said Sadarangani, an investigator at BC Children’s Hospital.

More research is needed to understand why this might not be the case for mRNA COVID-19 vaccines, Sadarangani said, but he suspects the physical transformation of pregnancy could be a factor.

“There’s a lot of hormonal and immunological and physiological changes happening during pregnancy, and some of them we understand, some of them we don’t,” he said. “I’m presuming that some of these changes are leading to these lower rates.”

Thursday’s study found that rates of serious health events after getting a COVID-19 vaccine, such as hospitalization, were similarly rare across all groups.

There was no significant difference in the rates of miscarriage or stillbirth among participants who were vaccinated and those who weren’t.

Researchers are conducting a followup survey to see if participants experienced any side-effects six months after their COVID-19 shots, Sadarangani said.

Pregnant people are at increased risk of COVID-19 complications, he said, so it’s all the more important that researchers continue to study how vaccination affects them and their babies.

“All of the data we have really highlight the safety of all of these vaccines in pregnancy,” said Sadarangani. “Ultimately, this is the best way to protect this group of people in our population.”

This report by The Canadian Press was first published Aug. 12, 2022.

Adblock test (Why?)



Source link

Continue Reading

Trending