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The COVID-19 virus keeps evolving. These ‘disease detectives’ are on the case

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The Omicron variant of the virus that causes COVID-19 was last year’s unpleasant holiday surprise. More than a year later, a loosely knit group of “disease detectives” across Canada continues to keep watch for key mutations.

Officials with the World Health Organization (WHO) say Omicron is better able to pass from person to person than previous versions of the virus.

And so researchers have shifted their attention to Omicron’s offspring.

“Are we ready to take the hit of another wave of a new variant that might emerge? I don’t think so,” Mike Ryan, the WHO emergencies chief, said of China’s latest outbreak at the agency’s last scheduled news conference of the year on Dec. 21.

Researchers look for mutations in the genetic sequence of the virus that might offer a variant a growth advantage over previous versions, cause more severe illness or help it to get around our immune defences.

“Omicron, the latest variant of concern, is the most transmissible variant we have seen so far, including all the subvariants that are in circulation, more than 500 of them. So we will continue to see surges of infection around the world,” said Maria Van Kerkhove, WHO’s technical lead for COVID-19.

It’s critical to continue to monitor known variants, as well as being able to detect new ones, so that strategies can be adjusted if needed, she said.

Like a wolf in sheep’s clothing

To Canadian variant tracker Fiona Brinkman, mutations in genetic sequences of SARS-CoV-2 offer important clues to identify trends and detect new clusters of cases or outbreaks.

“These viral sequences tell a little story about what’s happening right now that give us a hint about what the story will be to come,” said Brinkman, a professor of molecular biology and biochemistry at Simon Fraser University.

“You’re taking this data and then trying to be a detective.”

Travellers are pictured at Vancouver International Airport after a heavy snowfall in British Columbia last week. Canadian doctors and scientists are expecting a bump in COVID-19 cases after the holidays. (Ben Nelms/CBC)

When the virus mutates to something that’s harder for our immune system to recognize, then it’s harder to fight an infection.

“It’s literally like a wolf putting on sheep’s clothing,” Brinkman said.

Brinkman and her team are currently tracking “a whole soup of variants,” in part to predict what might happen so health-care officials can plan staffing amid ongoing shortages, overrun emergency departments and a lack of primary care.

“How big is that impact going to be in January, after the holiday season?” Brinkman asked. “We wouldn’t be surprised if we see a bump in cases.”

On the lookout for major new variant

Elsewhere in the country, Art Poon calls himself a scientist who specializes in tracking viruses — how they evolve and how they spread. His day job focuses on HIV.

Scientists use “molecular bread crumbs” left by the virus to figure out where COVID has moved between countries, he said.

“We would be looking for a rapid increase in the number of infections,” said Poon, an associate professor of virus evolution and bioinformatics at Western University in London, Ont. “Is it spreading faster than we would expect?”

But the decline in testing and sequencing for the virus means we’re “driving blind” in trying to make accurate predictions, said Brinkman.

 

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Poon, Brinkman and dozens of other trackers across Canada meet weekly, virtually, applying their computational and modelling skills to COVID-19. They also share their sequencing findings with international counterparts.

It’s important to realize that there’s “no big new variant” that we’re seeing right now, Brinkman said.

“That doesn’t mean one won’t occur. One of the important components about this work is to really catch those new variants that are really significant as soon as possible.”

The COVID-19 picture in Canada is increasingly unique in the world, given differences in when Omicron hits and how hard, as well as varying degrees of immunity from vaccinations.

Woman seated wearing speckled glasses.
Fiona Brinkman advocates for surveillance of variants in Canada because it’s now harder to apply what’s happened elsewhere in the world to make predictions for here, she says. (CBC)

“Surveillance within Canada is going to become very important,” Brinkman said. She advocates for surveillance here, because it’s now harder to apply what’s happened elsewhere in order to make predictions for Canada.

National data from the federal government’s COVID-19 Immunity Task Force suggests more than 70 per cent of people across the country have been infected. While there was a large jump in infections during Omicron waves in 2022, fewer of those aged 60 and older show protection from antibodies following infection.

Beyond COVID-19, Brinkman hopes to apply the tools scientists have developed during the pandemic to study other troublesome infections, like influenza.

“We are definitely going to be seeing new variants,” Brinkman said. “Whether that’s going to be COVID or whether that’s going to be flu is another story.”

As multiple respiratory infections like COVID-19, influenza and respiratory syncytial virus (RSV) continue to sicken Canadians and further stretch our health-care system and medical staff, Brinkman shared preventative advice backed by public health data.

“One of the best masks you can wear is a recent vaccine shot,” she said.

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Don’t fall for fake dentists offering veneers and other dental work on social media

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WASHINGTON (AP) — If you have stained or chipped teeth, you might be considering veneers, customized teeth coverings that can restore a photogenic smile without more extensive dental work.

But dentists warn that these pricey cosmetic enhancements are at the center of a worrisome online trend: unlicensed practitioners without proper training or supervision offering low-cost veneers.

These self-described “veneer techs” often promote themselves on Instagram and TikTok, promising a full set of veneers for less than half of what dentists typically charge. Some also market their own training courses and certifications for people looking to get into the business.

It’s misleading, health professionals warn — and illegal. All states require dental work, including veneers, to be performed under the supervision of a licensed dentist.

On Thursday, Georgia law enforcement officials arrested Brandon Diller, who promoted himself to 158,000 Instagram followers as “Atlanta’s top veneer specialist and trainer.” Diller practiced dentistry without a license and sold “training and certificates, which were worthless” and “provided no legitimate or legal credentials,” according to an arrest warrant from Fulton County’s District Attorney’s office.

Here’s what to know about veneers and how to avoid bogus providers and services:

What are dental veneers?

Veneers are thin, custom-made dental coverings used to hide minor imperfections or to fill in gaps between teeth. Unlike crowns or more invasive dental implants, veneers are almost always considered cosmetic dentistry and generally aren’t covered by insurance.

Dentists usually charge between $1,000 and $2,000 per tooth for veneers, with higher prices for those made from porcelain compared with lower-grade materials.

Placing veneers involves stripping some of the natural enamel from the tooth and bonding the new covering into place. Because of that process, getting veneers is considered an irreversible procedure, according to the American Dental Association. They are not permanent, and can be expected to last between 5 to 15 years before they degrade and need to be replaced.

In recent months the ADA has been stepping up warnings about the risks of veneer procedures done by unlicensed individuals.

“Quality control is lost without the involvement of a licensed dentist,” said Dr. Ada Cooper, a New York-based dentist and ADA spokesperson. “We undergo years of education and training and need to be licensed by various regulatory bodies before we can practice.”

What are the risks of getting veneers from someone who isn’t licensed?

Improper veneer procedures can cause a range of health problems, including severe pain, nerve damage and tooth loss.

Patients need to be anesthetized before the enamel is removed from their teeth.

“It could be incredibly painful if they’re not anesthetized correctly,” said Dr. Zach Truman, who runs an orthodontics practice in Las Vegas. “You can also go too deep into the tooth and penetrate what’s called the pulp chamber, which contains blood vessels and nerves.”

One of the biggest problems Truman sees with unregulated veneer work is that customers aren’t getting screened for existing dental problems, such as gum disease and cavities.

“If you put a veneer on a tooth that has an active cavity, you’re just going to seal it in there and eventually it’s going to progress to tooth loss,” Truman said.

Dental veneers aren’t the only option for improving the appearance of teeth. Over-the-counter whitening kits can help with minor stains and discoloration. And dentists can sometimes use composite materials to reshape chipped or uneven teeth. But Truman says those fillings are prone to crack and won’t last as long as veneers.

How can I spot bogus veneer providers online?

One clue: Many individuals performing unlicensed dental work promote themselves on social media as “veneer technicians.”

Instead of working out of a dental office they often perform treatments at beauty salons, hotel rooms or private homes. Some advertise multi-city tours and encourage clients to message them to book an appointment in advance.

Much of the appeal of the services is in their pricing, with some offering a full set of veneers for a flat fee of $4,000 or $5,000. That’s less than half of what patients can generally expect to pay at a dental office.

Performing dental work without an appropriate license is illegal, the ADA notes.

Dentists and hygienists are licensed by state governments, who also define the work dental assistants can perform. But in all cases, veneers and other dental procedures must be supervised by a licensed dentist.

Earlier this year, Illinois law enforcement officials arrested a woman running a business called the Veneer Experts after she posted videos of herself fitting braces, veneers and other dental products without a license. She was previously arrested in Nevada on similar allegations of practicing dentistry without a license.

What are the best ways to find legitimate dental providers?

The ADA maintains a website detailing the training and licensing requirements for dentists across the U.S. Most states also maintain websites where you can lookup and verify licensure information and find any past disciplinary actions for dentists and other health professionals.

“It’s really critical to understand that dentistry is a regulated health care profession that requires formal educations and licensure,” Cooper said.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

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Strike vote looms for Alberta nurses union as informal mediation talks unsuccessful

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EDMONTON – Alberta’s nurses could soon find themselves on the picket line as recent talks with the provincial government failed to secure a new agreement.

David Harrigan, with the United Nurses of Alberta, says last month’s informal mediation meetings were productive, but says the gap between the two sides seems too big to bridge.

The union is seeking 30 per cent pay raises spread over two years while the Alberta government’s offer is 7.5 per cent over four years.

Harrigan says the two sides also find themselves far apart on operational issues.

He says while both sides accept that there are serious problems in terms of staffing levels, they can’t agree on what to do about it.

The province says its hopeful an agreement can still be reached.

This report by The Canadian Press was first published Oct. 3, 2024.

The Canadian Press. All rights reserved.

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New Democrats hit Saskatchewan Party on health care

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Saskatchewan’s New Democrats are criticizing the Saskatchewan Party’s health-care record as the provincial election campaign enters its third day.

The NDP says the emergency room at Saskatoon’s Royal University Hospital reached 350 per cent capacity on Tuesday night, a situation it blames on the Saskatchewan Party and its leader, Scott Moe.

Nurses are set to rally at noon today at the provincial legislature in Regina, with the Saskatchewan Union of Nurses saying the health system is beset by issues including ER overcrowding, hallway beds and staffing shortages.

NDP Leader Carla Beck is set to hold a media availability at the legislature shortly after.

Moe is scheduled to make an announcement in Prince Albert this morning before visiting small businesses and the local campaign office in Warman.

Election day is Oct. 28.

This report by The Canadian Press was first published Oct. 3, 2024.

The Canadian Press. All rights reserved.

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